Restoring Sinus Rhythm Improves Baroreflex Function in Patients With Persistent Atrial Fibrillation.

abstract：BACKGROUND:Intravascular imaging can facilitate chronic total occlusion (CTO) percutaneous coronary intervention. METHODS AND RESULTS:We examined the frequency of use and outcomes of intravascular imaging among 619 CTO percutaneous coronary interventions performed between 2012 and 2015 at 7 US centers. Mean age was 65...

journal_title：Journal of the American Heart Association

authors： Karacsonyi J,Alaswad K,Jaffer FA,Yeh RW,Patel M,Bahadorani J,Karatasakis A,Danek BA,Doing A,Grantham JA,Karmpaliotis D,Moses JW,Kirtane A,Parikh M,Ali Z,Lombardi WL,Kandzari DE,Lembo N,Garcia S,Wyman MR,Alame A,

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:The p.Gln554X mutation in desmocollin-2 (DSC2) is prevalent in ≈10% of the Hutterite population. While the homozygous mutation causes severe biventricular arrhythmogenic right ventricular cardiomyopathy, the phenotypic features and prognosis of heterozygotes remain incompletely understood. METHODS AND RESUL...

journal_title：Journal of the American Heart Association

authors： Wong JA,Duff HJ,Yuen T,Kolman L,Exner DV,Weeks SG,Gerull B

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Pulse pressure (PP) is related to cardiac function, arterial stiffness, fluid status, and vascular events. This study aimed to explore the prognostic role of PP upon admission in patients with acute ischemic stroke (AIS) based on a nation-wide stroke registry. METHODS AND RESULTS:We evaluated the associatio...

journal_title：Journal of the American Heart Association

authors： Tang SC,Yin JH,Liu CH,Sun MH,Lee JT,Sun Y,Hsu CS,Sun MC,Lin CH,Chen CH,Lien LM,Muo CH,Jeng JS,Hsu CY,Taiwan Stroke Registry Investigators.

更新日期：2017-06-22 00:00:00

abstract：BACKGROUND:Medication adherence improves outcomes for patients with heart failure, but adherence rates remain low. We examined the association between earlier postdischarge follow-up and medication adherence. METHODS AND RESULTS:We performed a retrospective cohort study of patients ≥65 years who were hospitalized for ...

journal_title：Journal of the American Heart Association

authors： Chang LL,Xu H,DeVore AD,Matsouaka RA,Yancy CW,Fonarow GC,Allen LA,Hernandez AF

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Intracerebral hemorrhage (ICH) carries high risk for short-term mortality. We sought to identify race-specific predictors of mortality in ICH patients. METHODS AND RESULTS:We used 2 databases, the Johns Hopkins clinical stroke database and the Nationwide Inpatient Sample (NIS). We included 226 patients with...

journal_title：Journal of the American Heart Association

authors： Faigle R,Marsh EB,Llinas RH,Urrutia VC,Gottesman RF

更新日期：2016-08-16 00:00:00

abstract：:Background Soluble urokinase plasminogen activator receptor (su PAR ) is a proinflammatory biomarker associated with immune activation and fibrinolysis inhibition. Plasminogen activator inhibitor ( PAI -1) is associated with excessive fibrin accumulation, thrombus formation, and atherosclerosis. The relationship betwe...

journal_title：Journal of the American Heart Association

authors： Corban MT,Prasad A,Nesbitt L,Loeffler D,Herrmann J,Lerman LO,Lerman A

更新日期：2018-08-07 00:00:00

abstract：BACKGROUND:To address the lack of knowledge regarding the long-term risk of intracranial hemorrhage (ICH) after acute myocardial infarction (AMI), the aims of this study were to: (1) investigate the incidence, time trends, and predictors of ICH in a large population within 1 year of discharge after AMI; (2) investigate...

journal_title：Journal of the American Heart Association

authors： Graipe A,Binsell-Gerdin E,Söderström L,Mooe T

更新日期：2015-12-11 00:00:00

abstract：BACKGROUND:Transcatheter pulmonary valve implantation is approved for the treatment of dysfunctional right ventricle to pulmonary artery conduits. However, the literature is limited because of a small patient population, and it does not reflect changing procedural practice patterns over the last decade. METHODS AND RE...

journal_title：Journal of the American Heart Association

authors： Chatterjee A,Bajaj NS,McMahon WS,Cribbs MG,White JS,Mukherjee A,Law MA

更新日期：2017-08-04 00:00:00

abstract：BACKGROUND:Right ventricular (RV) diastolic function is impaired in patients with pulmonary arterial hypertension (PAH). Our previous study showed that elevated cardiomyocyte stiffness and myofilament Ca(2+) sensitivity underlie diastolic dysfunction in PAH. This study investigates protein modifications contributing to...

journal_title：Journal of the American Heart Association

authors： Rain S,Bos Dda S,Handoko ML,Westerhof N,Stienen G,Ottenheijm C,Goebel M,Dorfmüller P,Guignabert C,Humbert M,Bogaard HJ,Remedios CD,Saripalli C,Hidalgo CG,Granzier HL,Vonk-Noordegraaf A,van der Velden J,de Man FS

更新日期：2014-06-03 00:00:00

abstract：BACKGROUND:Bypass grafting remains the standard of care for coronary artery disease and severe lower extremity ischemia. Efficacy is limited by poor long-term venous graft patency secondary to intimal hyperplasia (IH) caused by venous injury upon exposure to arterial pressure. We investigate whether photochemical tissu...

journal_title：Journal of the American Heart Association

authors： Goldstone RN,McCormack MC,Khan SI,Salinas HM,Meppelink A,Randolph MA,Watkins MT,Redmond RW,Austen WG Jr

更新日期：2016-07-27 00:00:00

abstract：:Background Aerobic exercise capacity is inversely associated with cardiovascular and all-cause mortality in men and women without coronary artery disease (CAD); however, a higher amount of vigorous exercise is associated with a J-shaped relationship in CAD patients. Therefore, the optimal type and amount of exercise f...

journal_title：Journal of the American Heart Association

authors： Malik A,Kanduri JS,Asbeutah AAA,Khraishah H,Shen C,Welty FK

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:There are few data relating novel measures of left ventricular (LV) mechanical function to cardiovascular disease (CVD) outcomes in the community. Whether distinct components of LV mechanical function provide information regarding risk for different CVD outcomes is unclear. METHODS AND RESULTS:We used speck...

journal_title：Journal of the American Heart Association

authors： Cheng S,McCabe EL,Larson MG,Merz AA,Osypiuk E,Lehman BT,Stantchev P,Aragam J,Solomon SD,Benjamin EJ,Vasan RS

更新日期：2015-10-27 00:00:00

abstract：BACKGROUND:Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from murine atherosclerosis models, evidence of B-cell involvement in human atherosclerotic disease is limited. We therefore investigated the association of circulating ...

journal_title：Journal of the American Heart Association

authors： Meeuwsen JAL,van Duijvenvoorde A,Gohar A,Kozma MO,van de Weg SM,Gijsberts CM,Haitjema S,Björkbacka H,Fredrikson GN,de Borst GJ,den Ruijter HM,Pasterkamp G,Binder CJ,Hoefer IE,de Jager SCA

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:Epidemiological evidence suggests a cardioprotective role of α-linolenic acid (ALA), a plant-derived ω-3 fatty acid. It is unclear whether ALA is beneficial in a background of high marine ω-3 fatty acids (long-chain n-3 polyunsaturated fatty acids) intake. In persons at high cardiovascular risk from Spain, a...

journal_title：Journal of the American Heart Association

authors： Sala-Vila A,Guasch-Ferré M,Hu FB,Sánchez-Tainta A,Bulló M,Serra-Mir M,López-Sabater C,Sorlí JV,Arós F,Fiol M,Muñoz MA,Serra-Majem L,Martínez JA,Corella D,Fitó M,Salas-Salvadó J,Martínez-González MA,Estruch R,Ros E,P

更新日期：2016-01-26 00:00:00

abstract：BACKGROUND:Several studies have shown an inverse relationship between ideal cardiovascular health (CVH) and mortality. However, there are no studies that pool these data to show the shape of the relationship and quantify the mortality benefit from ideal CVH. METHODS AND RESULTS:We conducted a systematic internet liter...

journal_title：Journal of the American Heart Association

authors： Aneni EC,Crippa A,Osondu CU,Valero-Elizondo J,Younus A,Nasir K,Veledar E

更新日期：2017-12-21 00:00:00

abstract：BACKGROUND:Clinical symptoms are part of the risk stratification approaches used in the emergency department (ED) to evaluate patients with suspected acute coronary syndromes (ACS). The objective of this study was to determine the sensitivity, specificity, and predictive value of 13 symptoms for a discharge diagnosis o...

journal_title：Journal of the American Heart Association

authors： Devon HA,Rosenfeld A,Steffen AD,Daya M

更新日期：2014-04-02 00:00:00

abstract：BACKGROUND:Increased platelet aggregation during antiplatelet therapy may predict cardiovascular events in patients with coronary artery disease. The majority of these patients receive aspirin monotherapy. We aimed to investigate whether high platelet-aggregation levels predict cardiovascular events in stable coronary ...

journal_title：Journal of the American Heart Association

authors： Larsen SB,Grove EL,Neergaard-Petersen S,Würtz M,Hvas AM,Kristensen SD

更新日期：2017-08-05 00:00:00

abstract：BACKGROUND:Clinical guidelines recommend using predicted atherosclerotic cardiovascular disease (ASCVD) risk to inform treatment decisions. The objective was to compare the contribution of changes in modifiable risk factors versus aging to the development of high 10-year predicted ASCVD risk. METHODS AND RESULTS:A pro...

journal_title：Journal of the American Heart Association

authors： Bress AP,Colantonio LD,Booth JN 3rd,Spruill TM,Ravenell J,Butler M,Shallcross AJ,Seals SR,Reynolds K,Ogedegbe G,Shimbo D,Muntner P

更新日期：2017-02-08 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a major risk factor for the development of chronic kidney disease. Nuclear factor-κB is a nuclear transcription factor activated post-ischemia, responsible for the transcription of proinflammatory proteins. The role of nuclear factor-κB in the renal fibrosis post-AKI is unknown. ...

journal_title：Journal of the American Heart Association

authors： Johnson FL,Patel NSA,Purvis GSD,Chiazza F,Chen J,Sordi R,Hache G,Merezhko VV,Collino M,Yaqoob MM,Thiemermann C

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Psychosocial characteristics have a strong effect on risk of depression, and their direct treatment with behavioral interventions reduces rates of depression. Because new-onset poststroke depression (NPSD) is frequent, devastating, and often treatment-resistant, novel preventive efforts are needed. As a firs...

journal_title：Journal of the American Heart Association

authors： Salinas J,Ray RM,Nassir R,Lakshminarayan K,Dording C,Smoller J,Wassertheil-Smoller S,Rosand J,Dunn EC

更新日期：2017-02-01 00:00:00

abstract：:Background There are spatial disparities in cardiovascular disease (CVD) mortality related to area-level socioeconomic status (SES) disadvantage, but little is known about the spatial distribution of CVD mortality according to built environment factors. We examined joint associations of neighborhood walkability attrib...

journal_title：Journal of the American Heart Association

authors： Koohsari MJ,Nakaya T,Hanibuchi T,Shibata A,Ishii K,Sugiyama T,Owen N,Oka K

更新日期：2020-06-16 00:00:00

abstract：:Background Cardiovascular disease incidence, prevalence, morbidity, and mortality have declined in the past several decades; however, disparities persist among subsets of the population. Notably, blacks have not experienced the same improvements on the whole as whites. Furthermore, frequent reports of relatively poore...

journal_title：Journal of the American Heart Association

authors： Islam SJ,Kim JH,Topel M,Liu C,Ko YA,Mujahid MS,Sims M,Mubasher M,Ejaz K,Morgan-Billingslea J,Jones K,Waller EK,Jones D,Uppal K,Dunbar SB,Pemu P,Vaccarino V,Searles CD,Baltrus P,Lewis TT,Quyyumi AA,Taylor H

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Serum bicarbonate varies over time in chronic kidney disease (CKD) patients, and this variability may portend poor cardiovascular outcomes. The aim of this study was to conduct a time-updated longitudinal analysis to evaluate the association of serum bicarbonate with long-term clinical outcomes: heart failur...

journal_title：Journal of the American Heart Association

authors： Dobre M,Yang W,Pan Q,Appel L,Bellovich K,Chen J,Feldman H,Fischer MJ,Ham LL,Hostetter T,Jaar BG,Kallem RR,Rosas SE,Scialla JJ,Wolf M,Rahman M,CRIC Study Investigators.

更新日期：2015-04-20 00:00:00

abstract：:Background Exposure to chronic psychosocial stress is a risk factor for atherosclerosis-based cardiovascular disease. We previously demonstrated the increased expressions of cathepsin S (CatS) in atherosclerotic lesions. Whether CatS participates directly in stress-related neointimal hyperplasia has been unknown. Meth...

journal_title：Journal of the American Heart Association

authors： Wang H,Meng X,Piao L,Inoue A,Xu W,Yu C,Nakamura K,Hu L,Sasaki T,Wu H,Unno K,Umegaki H,Murohara T,Shi GP,Kuzuya M,Cheng XW

更新日期：2019-07-16 00:00:00

abstract：:Background Antazoline mesylate represents an antihistamine capable of rapid and safe cardioversion of atrial fibrillation, yet evidence concerning its efficacy in comparison to other medications is insufficient. The study aimed to evaluate the success rate and safety of pharmacological cardioversion of atrial fibrilla...

journal_title：Journal of the American Heart Association

authors： Wybraniec MT,Wróbel W,Wilkosz K,Wrona K,Bula K,Mizia-Stec K

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Longer QRS duration (QRSd) improves, but increased left ventricular (LV) end-diastolic volume (LVEDV) reduces, efficacy of cardiac resynchronization therapy (CRT). QRSd/LVEDV ratios differ between sexes. We hypothesized that in the EchoCRT (Echocardiography Guided Cardiac Resynchronization Therapy) trial enr...

journal_title：Journal of the American Heart Association

authors： Varma N,Sogaard P,Bax JJ,Abraham WT,Borer JS,Dickstein K,Singh JP,Gras D,Holzmeister J,Brugada J,Ruschitzka F

更新日期：2018-05-27 00:00:00

abstract：BACKGROUND:Although several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure patients remains a challenge. The aim of this study was to develop and validate a risk score for early prediction of AKI in acute decompensated heart failure patients....

journal_title：Journal of the American Heart Association

authors： Zhou LZ,Yang XB,Guan Y,Xu X,Tan MT,Hou FF,Chen PY

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Recent studies using stress-rest perfusion cardiovascular magnetic resonance (CMR) demonstrated a close correlation between myocardial ischemia and reduced fractional flow reserve (FFR). However, its diagnostic concordance may be reduced in patients with multivessel disease. We sought to evaluate the concord...

journal_title：Journal of the American Heart Association

authors： Nakamori S,Sakuma H,Dohi K,Ishida M,Tanigawa T,Yamada A,Takase S,Nakajima H,Sawai T,Masuda J,Nagata M,Ichikawa Y,Kitagawa K,Fujii E,Yamada N,Ito M

更新日期：2018-01-26 00:00:00

abstract：:Background We aimed to determine if there is an association between hospital quality and the likelihood of a given hospital being a preferred transfer destination for stroke patients. Methods and Results Data from Medicare claims identified acute ischemic stroke transferred between 394 northeast US hospitals from 2007...

journal_title：Journal of the American Heart Association

authors： Zachrison KS,Onnela JP,Reeves MJ,Hernandez A,Camargo CA Jr,Zhao X,Matsouaka RA,Goldstein JN,Metlay JP,Schwamm LH

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:Sleep disordered breathing in children is associated with increased blood flow velocity and sympathetic overactivity. Sympathetic overactivity results in peripheral vasoconstriction and reduced systemic vascular compliance, which increases blood flow velocity during systole. Augmented blood flow velocity is ...

journal_title：Journal of the American Heart Association

authors： Kontos A,Lushington K,Martin J,Schwarz Q,Green R,Wabnitz D,Xu X,M Sokoya E,Willoughby S,Baumert M,Ferrante A,La Forgia M,Kennedy D

更新日期：2017-07-17 00:00:00