Hospital Factors Associated With Interhospital Transfer Destination for Stroke in the Northeast United States.

abstract：BACKGROUND:Transseptal puncture is a critical step in achieving left atrial (LA) access for a variety of cardiac procedures. Although the mechanical Brockenbrough needle has historically been used for this procedure, a needle employing radiofrequency (RF) energy has more recently been approved for clinical use. We soug...

journal_title：Journal of the American Heart Association

authors： Hsu JC,Badhwar N,Gerstenfeld EP,Lee RJ,Mandyam MC,Dewland TA,Imburgia KE,Hoffmayer KS,Vedantham V,Lee BK,Tseng ZH,Scheinman MM,Olgin JE,Marcus GM

更新日期：2013-09-17 00:00:00

abstract：BACKGROUND:Short-term exposures to fine (<2.5 μm aerodynamic diameter) ambient particulate-matter (PM) have been related with increased blood pressure (BP) in controlled-human exposure and community-based studies. However, whether coarse (2.5 to 10 μm) PM exposure increases BP is uncertain. Recent observational studies...

journal_title：Journal of the American Heart Association

authors： Bellavia A,Urch B,Speck M,Brook RD,Scott JA,Albetti B,Behbod B,North M,Valeri L,Bertazzi PA,Silverman F,Gold D,Baccarelli AA

更新日期：2013-06-19 00:00:00

abstract：:Background Ankle-brachial indexes (ABI) are a noninvasive diagnostic tool for peripheral arterial disease and a marker of increased cardiovascular risk. ABI is calculated using the highest systolic blood pressure of the 4 ankle arteries (bilateral dorsalis pedis and posterior tibial). Accordingly, patients may be assi...

journal_title：Journal of the American Heart Association

authors： Firth C,Tseng AS,Abdelmalek M,Girardo M,Atwal D,Cooper L,McBane R,Pollak A,Liedl D,Wennberg P,Shamoun FE

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:Insulin resistance, characterized by hyperinsulinemia and normal or elevated serum glucose, is an established precursor to diabetes and cardiovascular disease. Despite fasting serum C-peptide levels being an accurate and stable marker of endogenous insulin production used in patients with diabetes, it is unk...

journal_title：Journal of the American Heart Association

authors： Patel N,Taveira TH,Choudhary G,Whitlatch H,Wu WC

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:There is paucity of knowledge concerning the specific age in youth when the associations of metabolic syndrome (MetS) begin to be operative. Thus, we investigated the relation of age to the associations of childhood MetS with adult MetS, type 2 diabetes mellitus and high carotid intima-media thickness. METH...

journal_title：Journal of the American Heart Association

authors： Koskinen J,Magnussen CG,Sinaiko A,Woo J,Urbina E,Jacobs DR Jr,Steinberger J,Prineas R,Sabin MA,Burns T,Berenson G,Bazzano L,Venn A,Viikari JSA,Hutri-Kähönen N,Raitakari O,Dwyer T,Juonala M

更新日期：2017-08-16 00:00:00

abstract：:Background Monocular vision loss, attributed to either central retinal artery occlusion ( CRAO ), branch retinal artery occlusion ( BRAO ), or ocular ischemic syndrome ( OIS ), is thought to be associated with an increased prevalence of cerebral infarcts. However, there is a paucity of data substantiating this. We aim...

journal_title：Journal of the American Heart Association

authors： Avery MB,Magal I,Kherani A,Mitha AP

更新日期：2019-02-05 00:00:00

abstract：:Background The majority of studies evaluating cardiorespiratory fitness ( CRF ) as a cardiovascular risk factor use cardiovascular mortality and not cardiovascular disease events as the primary end point, and generally do not include women. The aim of this study was to investigate the association of estimated CRF ( eC...

journal_title：Journal of the American Heart Association

authors： Shigdel R,Dalen H,Sui X,Lavie CJ,Wisløff U,Ernstsen L

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:CSL112 is a new formulation of human apolipoprotein A-I (apoA-I) being developed to reduce cardiovascular events following acute coronary syndrome. This phase 2a, randomized, double-blind, multicenter, dose-ranging trial represents the first clinical investigation to assess the safety and pharmacokinetics/ph...

journal_title：Journal of the American Heart Association

authors： Tricoci P,D'Andrea DM,Gurbel PA,Yao Z,Cuchel M,Winston B,Schott R,Weiss R,Blazing MA,Cannon L,Bailey A,Angiolillo DJ,Gille A,Shear CL,Wright SD,Alexander JH

更新日期：2015-08-25 00:00:00

abstract：:Background Patients undergoing lead extraction for infected devices have worse outcomes compared with those with noninfected devices. We assessed predictors of in-hospital mortality and procedure-related major adverse events (MAEs) in a large cohort undergoing lead extraction. Methods and Results Deidentified hospital...

journal_title：Journal of the American Heart Association

authors： Aleong RG,Zipse MM,Tompkins C,Aftab M,Varosy P,Sauer W,Kao D

更新日期：2020-04-07 00:00:00

abstract：:Background Normal-flow, low-gradient severe aortic stenosis (NF-LG-SAS), defined by aortic valve area <1 cm2, mean gradient <40 mm Hg, and indexed stroke volume >35 mL/m2, is the most prevalent form of low-gradient aortic stenosis (AS). However, the true severity of AS and the management of NF-LG-SAS are controversial...

journal_title：Journal of the American Heart Association

authors： Chadha G,Bohbot Y,Rusinaru D,Maréchaux S,Tribouilloy C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Although clinical trials have proved that statin can be used prophylactically against cardiovascular events, the direct effects of statin on plaque development are not well understood. We generated low-density lipoprotein receptor knockout (LDLR(-/-)) pigs to study the effects of early statin administration ...

journal_title：Journal of the American Heart Association

authors： Li Y,Fuchimoto D,Sudo M,Haruta H,Lin QF,Takayama T,Morita S,Nochi T,Suzuki S,Sembon S,Nakai M,Kojima M,Iwamoto M,Hashimoto M,Yoda S,Kunimoto S,Hiro T,Matsumoto T,Mitsumata M,Sugitani M,Saito S,Hirayama A,Onish

更新日期：2016-04-18 00:00:00

abstract：BACKGROUND:Low high-density lipoprotein (HDL) levels are major predictors of cardiovascular (CV) events, even in patients on statin treatment with low-density lipoprotein (LDL) at target. In animal models HDLs protect LDL from oxidation and blunt platelet activation. Our study aimed to examine whether HDL levels are re...

journal_title：Journal of the American Heart Association

authors： Vazzana N,Ganci A,Cefalù AB,Lattanzio S,Noto D,Santoro N,Saggini R,Puccetti L,Averna M,Davì G

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:Perioperative antiplatelet agents potentially increase bleeding after non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The protease-activated receptor 1 antagonist vorapaxar reduced cardiovascular events and was associated with increased bleeding versus placebo in NSTE ACS, but its efficacy an...

journal_title：Journal of the American Heart Association

authors： van Diepen S,Tricoci P,Podder M,Westerhout CM,Aylward PE,Held C,Van de Werf F,Strony J,Wallentin L,Moliterno DJ,White HD,Mahaffey KW,Harrington RA,Armstrong PW

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Left ventricular noncompaction (LVNC) has since been classified as a primary genetic cardiomyopathy, but the genetic basis is not fully evaluated. The aim of the present study was to identify the genetic spectrum using next-generation sequencing and to evaluate genotype-phenotype correlations in LVNC patient...

journal_title：Journal of the American Heart Association

authors： Wang C,Hata Y,Hirono K,Takasaki A,Ozawa SW,Nakaoka H,Saito K,Miyao N,Okabe M,Ibuki K,Nishida N,Origasa H,Yu X,Bowles NE,Ichida F,for LVNC Study Collaborators.

更新日期：2017-08-30 00:00:00

abstract：:Background Gait speed is a reliable measure of physical function and frailty in patients with aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Slow gait speed pre-TAVR predicts worse clinical outcomes post-TAVR. The consequences of improved versus worsened physical function post-TAVR are unkno...

journal_title：Journal of the American Heart Association

authors： Goel K,O'Leary JM,Barker CM,Levack M,Rajagopal V,Makkar RR,Bajwa T,Kleiman N,Linke A,Kereiakes DJ,Waksman R,Allocco DJ,Rizik DG,Reardon MJ,Lindman BR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Postural tachycardia syndrome (POTS) is a disorder of chronic orthostatic intolerance accompanied by excessive orthostatic tachycardia. Patients with POTS commonly have comorbid conditions such as attention deficit hyperactivity disorder, depression, or fibromyalgia that are treated with medications that inh...

journal_title：Journal of the American Heart Association

authors： Green EA,Raj V,Shibao CA,Biaggioni I,Black BK,Dupont WD,Robertson D,Raj SR

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:We previously identified peritoneal B1a cells that secrete natural IgM as a key atheroprotective B cell subset. However, the molecules that activate atheroprotective B1a cells are unknown. Here, we investigated whether Toll-like receptors (TLRs) TLR2, TLR4, and TLR9 expressed by B1a cells are required for Ig...

journal_title：Journal of the American Heart Association

authors： Hosseini H,Li Y,Kanellakis P,Tay C,Cao A,Liu E,Peter K,Tipping P,Toh BH,Bobik A,Kyaw T

更新日期：2016-11-14 00:00:00

abstract：:Background Apolipoprotein CIII (apo CIII ) is a crucial player in triglyceride-rich lipoprotein metabolism, but may also act pleiotropically, provoking inflammatory responses and stimulating coagulation. Elevated apo CIII plasma levels have been associated with increased activity of coagulation factors. Since these fe...

journal_title：Journal of the American Heart Association

authors： Olivieri O,Turcato G,Moruzzi S,Castagna A,Girelli D,Pizzolo F,Friso S,Sandri M,Bassi A,Martinelli N

更新日期：2019-01-22 00:00:00

abstract：:Background Muscular dystrophy (MD) causes a progressive cardiomyopathy characterized by diffuse fibrosis, arrhythmia, heart failure, and early death. Activation of the thromboxane-prostanoid receptor (TPr) increases calcium transients in cardiomyocytes and is proarrhythmic and profibrotic. We hypothesized that TPr act...

journal_title：Journal of the American Heart Association

authors： West JD,Galindo CL,Kim K,Shin JJ,Atkinson JB,Macias-Perez I,Pavliv L,Knollmann BC,Soslow JH,Markham LW,Carrier EJ

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:Long chain acyl-CoA synthetases (ACSL) catalyze long-chain fatty acids (FA) conversion to acyl-CoAs. Temporal ACSL1 inactivation in mouse hearts (Acsl1(H-/-)) impaired FA oxidation and dramatically increased glucose uptake, glucose oxidation, and mTOR activation, resulting in cardiac hypertrophy. We used unb...

journal_title：Journal of the American Heart Association

authors： Schisler JC,Grevengoed TJ,Pascual F,Cooper DE,Ellis JM,Paul DS,Willis MS,Patterson C,Jia W,Coleman RA

更新日期：2015-02-24 00:00:00

abstract：BACKGROUND:Current American Heart Association/American College of Cardiology guidelines recommend the GRACE (Global Registry of Acute Coronary Events) and TIMI (Thrombolysis in Myocardial Infarction) scores to assess myocardial infarction (MI) prognosis. Changes in the epidemiological characteristics of MI and the avai...

journal_title：Journal of the American Heart Association

authors： Gerber Y,Weston SA,Enriquez-Sarano M,Jaffe AS,Manemann SM,Jiang R,Roger VL

更新日期：2017-10-20 00:00:00

abstract：:Background Postpericardiotomy syndrome ( PPS ) is a common complication after cardiac surgery. However, large-scale epidemiological studies about the effect of procedure type on the occurrence of PPS and mortality of patients with PPS have not yet been performed. Methods and Results We studied the association of PPS o...

journal_title：Journal of the American Heart Association

authors： Lehto J,Kiviniemi T,Gunn J,Airaksinen J,Rautava P,Kytö V

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Orthostatic hypotension causes ≈80 000 hospitalizations per year in the United States. Treatments for orthostatic hypotension include fludrocortisone, a mineralocorticoid analog that promotes sodium reabsorption; and midodrine, an α-1 adrenergic agonist that is a direct vasoconstrictor. Although both medicat...

journal_title：Journal of the American Heart Association

authors： Grijalva CG,Biaggioni I,Griffin MR,Shibao CA

更新日期：2017-10-12 00:00:00

abstract：:Background Hyperkalemia has been associated with increased mortality in patients with myocardial infarction, but few data exist regarding hyperkalemia in cardiac intensive care unit ( CICU ) patients. We hypothesize that hyperkalemia is associated with increased mortality in unselected CICU patients. Methods and Resul...

journal_title：Journal of the American Heart Association

authors： Brueske B,Sidhu MS,Schulman-Marcus J,Kashani KB,Barsness GW,Jentzer JC

更新日期：2019-04-02 00:00:00

abstract：:Background We examined temporal trends, timing, and frequency, as well as adverse neonatal and maternal outcomes occurring in the first year postpartum among women experiencing syncope during pregnancy. Methods and Results This was a retrospective study of pregnancies between January 1, 2005, and December 31, 2014, in...

journal_title：Journal of the American Heart Association

authors： Chatur S,Islam S,Moore LE,Sandhu RK,Sheldon RS,Kaul P

更新日期：2019-05-21 00:00:00

abstract：:Background Sex-specific differences may influence prognosis after deferred revascularization following fractional flow reserve (FFR) measurement. This study sought to investigate the sex differences in long-term prognosis of patients with deferred revascularization following FFR assessment. Methods and Results A total...

journal_title：Journal of the American Heart Association

authors： Hoshino M,Hamaya R,Kanaji Y,Kanno Y,Hada M,Yamaguchi M,Sumino Y,Hirano H,Horie T,Usui E,Sugiyama T,Murai T,Lee T,Yonetsu T,Lee JM,Choi KH,Hwang D,Park J,Jung JH,Kim HY,Jung HW,Cho YK,Yoon HJ,Song YB,Hahn J

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Little is known about the hemodynamic response to exercise in heart failure patients at various ages before and after heart transplantation (HT). This information is important because postoperative hemodynamics may be a predictor of survival. To investigate the hemodynamic response to HT and exercise, we gro...

journal_title：Journal of the American Heart Association

authors： Lundgren J,Rådegran G

更新日期：2015-07-21 00:00:00

abstract：BACKGROUND:The optimal timing to administer non-vitamin K oral anticoagulants (NOACs) in patients with acute ischemic stroke and atrial fibrillation is unclear. This prospective observational multicenter study evaluated the rates of early recurrence and major bleeding (within 90 days) and their timing in patients with ...

journal_title：Journal of the American Heart Association

authors： Paciaroni M,Agnelli G,Falocci N,Tsivgoulis G,Vadikolias K,Liantinioti C,Chondrogianni M,Bovi P,Carletti M,Cappellari M,Zedde M,Ntaios G,Karagkiozi E,Athanasakis G,Makaritsis K,Silvestrelli G,Lanari A,Ciccone A,Putaala

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:Epinephrine administered during cardiopulmonary resuscitation (CPR) is associated with severe post-resuscitation myocardial dysfunction. We previously demonstrated that therapeutic hypothermia reduced the severity of post-resuscitation myocardial dysfunction caused by epinephrine; however, the relationship b...

journal_title：Journal of the American Heart Association

authors： Wang W,Hua T,Li H,Wu X,Bradley J,Peberdy MA,Ornato JP,Tang W

更新日期：2018-03-23 00:00:00

abstract：BACKGROUND:Morphine is commonly used to treat chest pain during myocardial infarction, but its effect on cardiovascular outcome has never been directly evaluated. The aim of this study was to examine the effect and safety of morphine in patients with acute anterior ST-segment elevation myocardial infarction followed up...

journal_title：Journal of the American Heart Association

authors： Bonin M,Mewton N,Roubille F,Morel O,Cayla G,Angoulvant D,Elbaz M,Claeys MJ,Garcia-Dorado D,Giraud C,Rioufol G,Jossan C,Ovize M,Guerin P,CIRCUS Study Investigators.

更新日期：2018-02-10 00:00:00