Equity and Noncommunicable Disease Reduction under the Sustainable Development Goals.

abstract：:Martin Gerdin and colleagues argue that disaster health interventions and decision-making can benefit from an evidence-based approach Please see later in the article for the Editors' Summary. ...

journal_title：PLoS medicine

authors： Gerdin M,Clarke M,Allen C,Kayabu B,Summerskill W,Devane D,MacLachlan M,Spiegel P,Ghosh A,Zachariah R,Gupta S,Barbour V,Murray V,von Schreeb J

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:In many European countries, medicines promotion is governed by voluntary codes of practice administered by the pharmaceutical industry under its own system of self-regulation. Involvement of industry organizations in policing promotion has been proposed to deter illicit conduct, but few detailed studies on s...

journal_title：PLoS medicine

authors： Zetterqvist AV,Merlo J,Mulinari S

更新日期：2015-02-17 00:00:00

abstract：BACKGROUND:Postpartum hemorrhage (PPH) is a leading cause of maternal death in sub-Saharan Africa. Although the World Health Organization recommends use of oxytocin for prevention of PPH, misoprostol use is increasingly common owing to advantages in shelf life and potential for sublingual administration. There is a lac...

journal_title：PLoS medicine

authors： Atukunda EC,Siedner MJ,Obua C,Mugyenyi GR,Twagirumukiza M,Agaba AG

更新日期：2014-11-04 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) released revised guidelines in 2015 recommending that all people living with HIV, regardless of CD4 count, initiate antiretroviral therapy (ART) upon diagnosis. However, few studies have projected the global resources needed for rapid scale-up of ART. Under the Health Poli...

journal_title：PLoS medicine

authors： Dutta A,Barker C,Kallarakal A

更新日期：2015-11-24 00:00:00

abstract：BACKGROUND:The "fitness" of an infectious pathogen is defined as the ability of the pathogen to survive, reproduce, be transmitted, and cause disease. The fitness of multidrug-resistant tuberculosis (MDRTB) relative to drug-susceptible tuberculosis is cited as one of the most important determinants of MDRTB spread and ...

journal_title：PLoS medicine

authors： Grandjean L,Gilman RH,Martin L,Soto E,Castro B,Lopez S,Coronel J,Castillo E,Alarcon V,Lopez V,San Miguel A,Quispe N,Asencios L,Dye C,Moore DA

更新日期：2015-06-23 00:00:00

abstract：:[This corrects the article DOI: 10.1371/journal.pmed.1002718.]. ...

journal_title：PLoS medicine

authors： Liu Z,Kuo PL,Horvath S,Crimmins E,Ferrucci L,Levine M

更新日期：2019-02-25 00:00:00

abstract：BACKGROUND:Through major efforts to reduce costs and expand access to antiretroviral therapy worldwide, widespread delivery of effective treatment to people living with HIV/AIDS is now conceivable even in severely resource-constrained settings. However, the potential epidemiologic impact of treatment in the context of ...

journal_title：PLoS medicine

authors： Salomon JA,Hogan DR,Stover J,Stanecki KA,Walker N,Ghys PD,Schwartländer B

更新日期：2005-01-01 00:00:00

abstract：:Prognostic models are abundant in the medical literature yet their use in practice seems limited. In this article, the third in the PROGRESS series, the authors review how such models are developed and validated, and then address how prognostic models are assessed for their impact on practice and patient outcomes, ill...

journal_title：PLoS medicine

authors： Steyerberg EW,Moons KG,van der Windt DA,Hayden JA,Perel P,Schroter S,Riley RD,Hemingway H,Altman DG,PROGRESS Group.

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab improves outcomes in patients with node-positive HER2+ early breast cancer. Given trastuzumab's high cost, we aimed to estimate its cost-effectiveness by heterogeneity in age and estrogen receptor (ER) and progesterone r...

journal_title：PLoS medicine

authors： Leung W,Kvizhinadze G,Nair N,Blakely T

更新日期：2016-08-09 00:00:00

abstract：BACKGROUND:The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas in past decades, a handful of tumor suppressors have been slowly identified using techniques such as link...

journal_title：PLoS medicine

authors： Chan TA,Glockner S,Yi JM,Chen W,Van Neste L,Cope L,Herman JG,Velculescu V,Schuebel KE,Ahuja N,Baylin SB

更新日期：2008-05-27 00:00:00

abstract：:In an Editorial, Guest Editors Nicola Low and Nathalie Broutet discuss the Collection on sexually transmitted infections in the context of research priorities in the field. ...

journal_title：PLoS medicine

authors： Low N,Broutet NJ

更新日期：2017-12-27 00:00:00

abstract：BACKGROUND:Childhood obstructive sleep apnea (OSA) is associated with neuropsychological deficits of memory, learning, and executive function. There is no evidence of neuronal brain injury in children with OSA. We hypothesized that childhood OSA is associated with neuropsychological performance dysfunction, and with ne...

journal_title：PLoS medicine

authors： Halbower AC,Degaonkar M,Barker PB,Earley CJ,Marcus CL,Smith PL,Prahme MC,Mahone EM

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:This paper examines the efforts of consultants affiliated with Philip Morris (PM), the world's leading transnational tobacco corporation, to influence scientific research and training in Thailand via the Chulabhorn Research Institute (CRI). A leading Southeast Asian institute for environmental health science...

journal_title：PLoS medicine

authors： Mackenzie R,Collin J

更新日期：2008-12-23 00:00:00

abstract：BACKGROUND:There have been increasing concerns regarding the safety and efficacy of neuroleptics in people with dementia, but there are very few long-term trials to inform clinical practice. The aim of this study was to determine the impact of long-term treatment with neuroleptic agents upon global cognitive decline an...

journal_title：PLoS medicine

authors： Ballard C,Lana MM,Theodoulou M,Douglas S,McShane R,Jacoby R,Kossakowski K,Yu LM,Juszczak E,Investigators DART AD.

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The relationship between population trends in delaying childbirth and rising rates of primary cesarean delivery is unclear. The aims of the present study were (1) to characterize the association between maternal age and the outcome of labor, (2) to determine the proportion of the increase in primary cesarean...

journal_title：PLoS medicine

authors： Smith GC,Cordeaux Y,White IR,Pasupathy D,Missfelder-Lobos H,Pell JP,Charnock-Jones DS,Fleming M

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is estimated to affect 130-180 million people worldwide. Although its origin is unknown, patterns of viral diversity suggest that HCV genotype 1 probably originated from West Africa. Previous attempts to estimate the spatiotemporal parameters of the virus, both globally and regionally...

journal_title：PLoS medicine

authors： Magiorkinis G,Magiorkinis E,Paraskevis D,Ho SY,Shapiro B,Pybus OG,Allain JP,Hatzakis A

更新日期：2009-12-01 00:00:00

abstract：:In this month's editorial, PLOS Medicine Editorial Board member Rachel Jewkes identifies challenges that the violence prevention research community faces in substantially reducing violence against women and girls over the next 30 years. Please see later in the article for the Editors' Summary. ...

journal_title：PLoS medicine

authors： Jewkes R

更新日期：2014-11-25 00:00:00

abstract：BACKGROUND:Helminth and protozoan infections affect more than 1 billion children globally. Improving water quality, sanitation, handwashing, and nutrition could be more sustainable control strategies for parasite infections than mass drug administration, while providing other quality of life benefits. METHODS AND FIND...

journal_title：PLoS medicine

authors： Pickering AJ,Njenga SM,Steinbaum L,Swarthout J,Lin A,Arnold BF,Stewart CP,Dentz HN,Mureithi M,Chieng B,Wolfe M,Mahoney R,Kihara J,Byrd K,Rao G,Meerkerk T,Cheruiyot P,Papaiakovou M,Pilotte N,Williams SA,Colford JM

更新日期：2019-06-26 00:00:00

abstract：BACKGROUND:Assessing the mortality impact of the 2009 influenza A H1N1 virus (H1N1pdm09) is essential for optimizing public health responses to future pandemics. The World Health Organization reported 18,631 laboratory-confirmed pandemic deaths, but the total pandemic mortality burden was substantially higher. We estim...

journal_title：PLoS medicine

authors： Simonsen L,Spreeuwenberg P,Lustig R,Taylor RJ,Fleming DM,Kroneman M,Van Kerkhove MD,Mounts AW,Paget WJ,GLaMOR Collaborating Teams.

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The cesarean section (CS) rate has risen globally during the last two decades. Effective and feasible strategies are needed to reduce it. The aim of this study was to assess the CS rate change after a two-stage intervention package that was designed to reduce the overall CS rate in Guangzhou, China. METHODS...

journal_title：PLoS medicine

authors： Xia X,Zhou Z,Shen S,Lu J,Zhang L,Huang P,Yu J,Yang L,Wang P,Lam KH,Jacobsson B,Mol BW,Xia H,Qiu X

更新日期：2019-07-08 00:00:00

abstract：BACKGROUND:The global tuberculosis epidemic results in nearly 2 million deaths and 9 million new cases of the disease a year. The vast majority of tuberculosis patients live in developing countries, where the diagnosis of tuberculosis relies on the identification of acid-fast bacilli on unprocessed sputum smears using ...

journal_title：PLoS medicine

authors： Steingart KR,Henry M,Laal S,Hopewell PC,Ramsay A,Menzies D,Cunningham J,Weldingh K,Pai M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Suboptimal weight gain during pregnancy is a potentially modifiable risk factor. We aimed to investigate the association between suboptimal gestational weight gain and severe adverse birth outcomes by pre-pregnancy body mass index (BMI) categories, including obesity class I to III. METHODS AND FINDINGS:We c...

journal_title：PLoS medicine

authors： Ukah UV,Bayrampour H,Sabr Y,Razaz N,Chan WS,Lim KI,Lisonkova S

更新日期：2019-12-30 00:00:00

abstract：:In an essay, Paul Bloem and Ikechukwu Ogbuanu discuss the public health implications of HPV vaccination. ...

journal_title：PLoS medicine

authors： Bloem P,Ogbuanu I

更新日期：2017-06-27 00:00:00

abstract：:Gordon C. Smith discusses the study by Katy Kozhimannil and colleagues that examines variations in cesarean section rates in the US and argues for the need for high-quality routine data collection to better understand the reasons for these variations. Please see later in the article for the Editors' Summary. ...

journal_title：PLoS medicine

authors： Smith GC

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:It remains unclear when standard systematic reviews and meta-analyses that rely on published aggregate data (AD) can provide robust clinical conclusions. We aimed to compare the results from a large cohort of systematic reviews and meta-analyses based on individual participant data (IPD) with meta-analyses o...

journal_title：PLoS medicine

authors： Tierney JF,Fisher DJ,Burdett S,Stewart LA,Parmar MKB

更新日期：2020-01-31 00:00:00

abstract：BACKGROUND:Artemisinin-based combination therapy (ACT) is recommended for uncomplicated Plasmodium vivax malaria in areas of emerging chloroquine resistance. We undertook a systematic review and individual patient data meta-analysis to compare the efficacies of dihydroartemisinin-piperaquine (DP) and artemether-lumefan...

journal_title：PLoS medicine

authors： Commons RJ,Simpson JA,Thriemer K,Abreha T,Adam I,Anstey NM,Assefa A,Awab GR,Baird JK,Barber BE,Chu CS,Dahal P,Daher A,Davis TME,Dondorp AM,Grigg MJ,Humphreys GS,Hwang J,Karunajeewa H,Laman M,Lidia K,Moore BR,M

更新日期：2019-10-04 00:00:00

abstract：BACKGROUND:Multidisciplinary care (MDC) programs have been proposed as a way to alleviate the cost and morbidity associated with chronic kidney disease (CKD) in the US. METHODS AND FINDINGS:We assessed the cost-effectiveness of a theoretical Medicare-based MDC program for CKD compared to usual CKD care in Medicare ben...

journal_title：PLoS medicine

authors： Lin E,Chertow GM,Yan B,Malcolm E,Goldhaber-Fiebert JD

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Identifying stage II patients with colorectal cancer (CRC) at higher risk of progression is a clinical priority in order to optimize the advantages of adjuvant chemotherapy while avoiding unnecessary toxicity. Recently, the intensity and the quality of the host immune response in the tumor microenvironment h...

journal_title：PLoS medicine

authors： Sanz-Pamplona R,Melas M,Maoz A,Schmit SL,Rennert H,Lejbkowicz F,Greenson JK,Sanjuan X,Lopez-Zambrano M,Alonso MH,Qu C,McDonnell KJ,Idos GE,Vignali M,Emerson R,Fields P,Guinó E,Santos C,Salazar R,Robins HS,Rennert

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:Previous epidemiological studies suggest that working-aged persons with a history of moderate-to-severe traumatic brain injury (TBI) may have an increased risk for developing neurodegenerative disease (NDD) while persons with a history of mild TBI do not. In this comprehensive nationwide study in Finland, we...

journal_title：PLoS medicine

authors： Raj R,Kaprio J,Korja M,Mikkonen ED,Jousilahti P,Siironen J

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:Trachoma is the world's leading cause of infectious blindness. The World Health Organization (WHO) has endorsed the SAFE strategy in order to eliminate blindness due to trachoma by 2020 through "surgery," "antibiotics," "facial cleanliness," and "environmental improvement." While the S and A components have ...

journal_title：PLoS medicine

authors： Stocks ME,Ogden S,Haddad D,Addiss DG,McGuire C,Freeman MC

更新日期：2014-02-25 00:00:00