The prognostic significance of the postoperative prognostic nutritional index in patients with colorectal cancer.

abstract：BACKGROUND:We analyzed the changes in permeability of endothelial cell layers after photon irradiation, with a focus on the metalloproteases ADAM10 and ADAM17, and on VE-cadherin, components crucial for the integrity of endothelial intercellular junctions, and their roles in the transmigration of cancer cells through e...

journal_title：BMC cancer

authors： Kouam PN,Rezniczek GA,Adamietz IA,Bühler H

更新日期：2019-10-16 00:00:00

abstract：BACKGROUND:Increased mammographic breast density is a moderate risk factor for breast cancer. Different scales have been proposed for classifying mammographic density. This study sought to assess intra-rater agreement for the most widely used scales (Wolfe, Tabár, BI-RADS and Boyd) and compare them in terms of classify...

journal_title：BMC cancer

authors： Garrido-Estepa M,Ruiz-Perales F,Miranda J,Ascunce N,González-Román I,Sánchez-Contador C,Santamariña C,Moreo P,Vidal C,Peris M,Moreno MP,Váquez-Carrete JA,Collado-García F,Casanova F,Ederra M,Salas D,Pollán M,DDM-Spain.

更新日期：2010-09-13 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) is associated with poorer outcomes in some cancers. Its effect on ovarian cancer is less clear. We consider the effect of DM on overall survival (OS) and progression free survival (PFS) in patients with epithelial ovarian cancer (EOC). METHODS:A retrospective cohort study of 215 patie...

journal_title：BMC cancer

authors： Akhavan S,Ghahghaei-Nezamabadi A,Modaresgilani M,Mousavi AS,Sepidarkish M,Tehranian A,Rezayof E

更新日期：2018-12-12 00:00:00

abstract：BACKGROUND:Breast cancer can impact survivors in many aspects of their life. Scarce information is currently available on the quality of life of cancer survivors in Bahrain. The objective of this study is to describe the quality of life of Bahraini women with breast cancer and its association with their sociodemographi...

journal_title：BMC cancer

authors： Jassim GA,Whitford DL

更新日期：2013-04-28 00:00:00

abstract：BACKGROUND:Myopericytoma is a rare and usually benign tumor, which is even rarer if it occurs in the liver and stomach space. Previous reports of myopericytoma were mostly related to its pathological manifestations, while imaging reports were rare. Here, we report the computed tomography (CT), computed tomography angio...

journal_title：BMC cancer

authors： Chen Z,Liang W

更新日期：2017-02-20 00:00:00

abstract：BACKGOUND:Oropharyngeal cancer (OPC) associated with human papilloma virus (HPV OPC) shows better treatment outcomes than non-HPV OPC. We investigated the expression of p53, β-tubulin, bcl-2 and ERCC 1, which are well-known biomarkers to predict the chemotherapy response, according to HPV status in OPC patients. METHO...

journal_title：BMC cancer

authors： Kim MJ,Ki MS,Kim K,Shim HJ,Hwang JE,Bae WK,Chung IJ,Lee DH,Lee JK,Yoon TM,Lim SC,Chung WK,Jeong JU,Lim HS,Choi YD,Cho SH

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:Annonaceous acetogenins are a family of natural products with antitumor activities. Annonaceous acetogenin mimic AA005 reportedly inhibits mammalian mitochondrial NADH-ubiquinone reductase (Complex I) and induces gastric cancer cell death. However, the mechanisms underlying its cell-death-inducing activity a...

journal_title：BMC cancer

authors： Han B,Wang TD,Shen SM,Yu Y,Mao C,Yao ZJ,Wang LS

更新日期：2015-03-18 00:00:00

abstract：BACKGROUND:Metastatic progression due to development or enrichment of therapy-resistant tumor cells is eventually lethal. Molecular characterization of such chemotherapy resistant tumor cell clones may identify markers responsible for malignant progression and potential targets for new treatment. Here, in a case of sta...

journal_title：BMC cancer

authors： Hjortland GO,Meza-Zepeda LA,Beiske K,Ree AH,Tveito S,Hoifodt H,Bohler PJ,Hole KH,Myklebost O,Fodstad O,Smeland S,Hovig E

更新日期：2011-10-20 00:00:00

abstract：BACKGROUND:Clinical studies implying the sunitinib multi-kinase inhibitor have led to disappointing results for breast cancer care but mostly focused on HER2-negative subtypes. Preclinical researches involving this drug mostly concern Triple Negative Breast Cancer (TNBC) murine models. Here, we explored the therapeutic...

journal_title：BMC cancer

authors： Thézé B,Bernards N,Beynel A,Bouet S,Kuhnast B,Buvat I,Tavitian B,Boisgard R

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS:To test the importance of TGFβ signaling to...

journal_title：BMC cancer

authors： Simms NA,Rajput A,Sharratt EA,Ongchin M,Teggart CA,Wang J,Brattain MG

更新日期：2012-06-06 00:00:00

abstract：BACKGROUND:Whether chronic inflammation increases prostate cancer risk remains unclear. This study investigated whether chronic inflammatory diseases (CID) or anti-inflammatory medication use (AIM) were associated with prostate cancer risk. METHODS:Fifty-five thousand nine hundred thirty-seven cases (all prostate canc...

journal_title：BMC cancer

authors： Beckmann K,Russell B,Josephs D,Garmo H,Haggstrom C,Holmberg L,Stattin P,Van Hemelrijck M,Adolfsson J

更新日期：2019-06-21 00:00:00

abstract：BACKGROUND:Malignant melanoma is an aggressive type of skin cancer, and despite recent advances in treatment, the survival rate of the metastatic form remains low. Nifuroxazide analogues are drugs based on the substitution of the nitrofuran group by benzofuroxan, in view of the pharmacophore similarity of the nitro gro...

journal_title：BMC cancer

authors： Farias CF,Massaoka MH,Girola N,Azevedo RA,Ferreira AK,Jorge SD,Tavares LC,Figueiredo CR,Travassos LR

更新日期：2015-10-27 00:00:00

abstract：BACKGROUND:The numerous side effects of chemotherapy in patients with breast cancer are well known. However, the precise effects of chemotherapy on ovarian function in premenopausal women are poorly investigated. The patients are at risk of developing sexual hormone deficiency and impaired fertility. This prospective c...

journal_title：BMC cancer

authors： Wenners A,Grambach J,Koss J,Maass N,Jonat W,Schmutzler A,Mundhenke C

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:The incidence of breast cancer among young women (aged ≤40 years) has increased in North America and Europe. Fewer than 10% of cases among young women are attributable to inherited BRCA1 or BRCA2 mutations, suggesting an important role for somatic mutations. This study investigated genomic differences betwee...

journal_title：BMC cancer

authors： Mealey NE,O'Sullivan DE,Pader J,Ruan Y,Wang E,Quan ML,Brenner DR

更新日期：2020-03-12 00:00:00

abstract：BACKGROUND:The Michigan Prevention Research Center, the University of Michigan Schools of Nursing, Public Health, and Medicine, and the Michigan Department of Community Health propose a multidisciplinary academic-clinical practice three-year project to increase breast cancer screening among young breast cancer survivor...

journal_title：BMC cancer

authors： Katapodi MC,Northouse LL,Schafenacker AM,Duquette D,Duffy SA,Ronis DL,Anderson B,Janz NK,McLosky J,Milliron KJ,Merajver SD,Duong LM,Copeland G

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:We sought to determine the comparative diagnostic performance of standard b-value (800-1000 s/mm2) versus low b-value (400-500 s/mm2) diffusion-weighted magnetic resonance imaging (DW-MRI) in the detection of renal cell carcinoma (RCC). METHOD:After a systematic review of the available literature, studies w...

journal_title：BMC cancer

authors： Tang Y,Zhou Y,Du W,Liu N,Zhang C,Ouyang T,Hu J

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:A disintegrin and metalloprotease 8 (ADAM8) has been reported to be associated with various malignancies. However, no studies have examined ADAM8 association in colorectal cancer (CRC). The aim of this study was to investigate the expression and function of ADAM8 in CRC. METHODS:Expression level of ADAM8 in...

journal_title：BMC cancer

authors： Yang Z,Bai Y,Huo L,Chen H,Huang J,Li J,Fan X,Yang Z,Wang L,Wang J

更新日期：2014-08-07 00:00:00

abstract：BACKGROUND:The incidence and survival rates for colorectal cancer in Australia are among the highest in the world. With population growth and ageing there are increasing numbers of colorectal cancer survivors in the community, yet little is known of their ongoing follow up and survivorship care experiences. This study ...

journal_title：BMC cancer

authors： Young JM,Durcinoska I,DeLoyde K,Solomon MJ

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Clinical characterization of bladder carcinomas is still inadequate using the standard clinico-pathological prognostic markers. We assessed the correlation between nm23-H1, Rb, EGFR and p53 in relation to the clinical outcome of patients with muscle invasive bilharzial bladder cancer (MI-BBC). METHODS:nm23-...

journal_title：BMC cancer

authors： Khaled HM,Bahnassy AA,Raafat AA,Zekri AR,Madboul MS,Mokhtar NM

更新日期：2009-01-26 00:00:00

abstract：BACKGROUND:Adding bevacizumab to chemotherapy improves response rates and progression-free survival (PFS) in metastatic breast cancer (mBC). We aimed to demonstrate decreased toxicity with metronomic chemotherapy/bevacizumab compared with paclitaxel/bevacizumab. METHODS:This multicenter, randomized phase III trial com...

journal_title：BMC cancer

authors： Rochlitz C,Bigler M,von Moos R,Bernhard J,Matter-Walstra K,Wicki A,Zaman K,Anchisi S,Küng M,Na KJ,Bärtschi D,Borner M,Rordorf T,Rauch D,Müller A,Ruhstaller T,Vetter M,Trojan A,Hasler-Strub U,Cathomas R,Winterhalde

更新日期：2016-10-10 00:00:00

abstract：BACKGROUND:The prognostic significance of FOXP3+ tumor-infiltrating lymphocytes (TILs) in patients with breast cancer remains controversial. The aims of our meta-analysis are to evaluate its association with clinicopathological characteristics and prognostic significance in patients with breast cancer. METHODS:PubMed,...

journal_title：BMC cancer

authors： Jiang D,Gao Z,Cai Z,Wang M,He J

更新日期：2015-10-17 00:00:00

abstract：BACKGROUND:Computational intelligence methods, including non-linear classification algorithms, can be used in medical research and practice as a decision making tool. This study aimed to evaluate the usefulness of artificial intelligence models for 5-year overall survival prediction in patients with cervical cancer tre...

journal_title：BMC cancer

authors： Obrzut B,Kusy M,Semczuk A,Obrzut M,Kluska J

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:The phase 3 MPACT trial in patients with metastatic pancreatic cancer demonstrated superior efficacy of nab-paclitaxel (nab-P) + gemcitabine (Gem) vs Gem monotherapy for all endpoints examined including overall survival, the primary endpoint. In the MPACT trial, patients were treated until progressive diseas...

journal_title：BMC cancer

authors： Vogel A,Römmler-Zehrer J,Li JS,McGovern D,Romano A,Stahl M

更新日期：2016-10-21 00:00:00

abstract：BACKGROUND:BRCA1 and BRCA2 mutations explain approximately one-fifth of the inherited susceptibility in high-risk Finnish hereditary breast and ovarian cancer (HBOC) families. EMSY is located in the breast cancer-associated chromosomal region 11q13. The EMSY gene encodes a BRCA2-interacting protein that has been implic...

journal_title：BMC cancer

authors： Määttä KM,Nurminen R,Kankuri-Tammilehto M,Kallioniemi A,Laasanen SL,Schleutker J

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:The mixture of volatile organic compounds in the headspace gas of urine may be able to distinguish lung cancer patients from relevant control populations. METHODS:Subjects with biopsy confirmed untreated lung cancer, and others at risk for developing lung cancer, provided a urine sample. A colorimetric sens...

journal_title：BMC cancer

authors： Mazzone PJ,Wang XF,Lim S,Choi H,Jett J,Vachani A,Zhang Q,Beukemann M,Seeley M,Martino R,Rhodes P

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:As one of the malignant tumors most often affecting children and young adults, Ewing sarcoma (ES) is characterized by early metastasis contributing to unfavorable prognosis. However, the molecular mechanisms responsible for ES metastasis remain poorly understood. In this study, we aimed to explore whether Wn...

journal_title：BMC cancer

authors： Jin Z,Zhao C,Han X,Han Y

更新日期：2012-10-18 00:00:00

abstract：BACKGROUND:18F-FDG PET/CT could satisfactorily show pancreatic and extra-pancreatic lesions in AIP, which can be mistaken for pancreatic cancer (PC). This study aimed to identify 18F-FDG PET/CT findings that might differentiate AIP from PC. METHODS:FDG-PET/CT findings of 26 AIP and 40 PC patients were reviewed. Pancre...

journal_title：BMC cancer

authors： Zhang J,Jia G,Zuo C,Jia N,Wang H

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Acrokeratosis paraneoplastica is a rare paraneoplastic phenomenon associated with upper aerodigestive tract carcinomas, usually manifesting as psoriasiform keratosis over the acral sites. It is primarily seen in white males above the age of 40 years. Here we report a case of paraneoplastic acrokeratosis in a...

journal_title：BMC cancer

authors： Hempen A,Samartzis EP,Kamarachev J,Fink D,Dedes KJ

更新日期：2015-07-08 00:00:00

abstract：BACKGROUND:Breast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer. Golgi related genes GOLPH3 has been reported to regulate many kinds of cancers proliferation. However, its u...

journal_title：BMC cancer

authors： Song Q,Chen Q,Wang Q,Yang L,Lv D,Jin G,Liu J,Li B,Fei X

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:Novel biomarkers are required to discern between breast tumors that should be targeted for treatment from those that would never become clinically apparent and/or life threatening for patients. Moreover, therapeutics that specifically target breast cancer (BC) cells with tumor-initiating capacity to prevent ...

journal_title：BMC cancer

authors： Hagerling C,Owyong M,Sitarama V,Wang CY,Lin C,van den Bijgaart RJE,Koopman CD,Brenot A,Nanjaraj A,Wärnberg F,Jirström K,Klein OD,Werb Z,Plaks V

更新日期：2020-06-10 00:00:00