Abstract:
BACKGROUND:Most women with psychotic disorders and bipolar disorders have children but their pregnancies are at risk of adverse psychiatric and fetal outcome. The extent of modifiable risk factors - both clinical and socio-demographic - is unclear as most studies have used administrative data or recruited from specialist tertiary referral clinics. We therefore aimed to investigate the socio-demographic and clinical characteristics of an epidemiologically representative cohort of pregnant women with affective and non-affective severe mental illness. METHODS:Women with severe mental illness were identified from a large electronic mental health case register in south London, and a data linkage with national maternity Hospital Episode Statistics identified pregnancies in 2007-2011. Data were extracted using structured fields, text searching and natural language processing applications. RESULTS:Of 456 pregnant women identified, 236 (51.7%) had schizophrenia and related disorders, 220 (48.3%) had affective psychosis or bipolar disorder. Women with schizophrenia and related disorders were younger, less likely to have a partner in pregnancy, more likely to be black, to smoke or misuse substances and had significantly more time in the two years before pregnancy in acute care (inpatient or intensive home treatment) compared with women with affective disorders. Both groups had high levels of domestic abuse in pregnancy (recorded in 18.9%), were from relatively deprived backgrounds and had impaired functioning measured by the Health of the Nation Outcome Scale. Women in the affective group were more likely to stop medication in the first trimester (39% versus 25%) whereas women with non-affective psychoses were more likely to switch medication. CONCLUSIONS:A significant proportion of women, particularly those with non-affective psychoses, have modifiable risk factors requiring tailored care to optimize pregnancy outcomes. Mental health professionals need to be mindful of the possibility of pregnancy in women of childbearing age and prescribe and address modifiable risk factors accordingly.
journal_name
BMC Psychiatryjournal_title
BMC psychiatryauthors
Taylor CL,Stewart R,Ogden J,Broadbent M,Pasupathy D,Howard LMdoi
10.1186/s12888-015-0451-8subject
Has Abstractpub_date
2015-04-17 00:00:00pages
88issn
1471-244Xpii
10.1186/s12888-015-0451-8journal_volume
15pub_type
杂志文章相关文献
BMC Psychiatry文献大全abstract:BACKGROUND:While considerable progress has been made in exploring the psychological, the neural, and the neurochemical dimensions of OCD separately, their interplay is still an open question, especially their changes during psychotherapy. METHODS:Seventeen patients were assessed at these three levels by psychological ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-02913-5
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:Individuals with major depressive disorder (MDD) and bipolar disorder (BD) have particularly high rates of chronic non-cancer pain (CNCP) and are also more likely to receive prescription opioids for their pain. However, there have been no known studies published to date that have examined opioid treatment pa...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-2456-1
更新日期:2020-01-31 00:00:00
abstract:BACKGROUND:Mood and anxiety disorders are leading causes of disability and mortality, due largely to their onset during adolescence and young adulthood and broader impact on functioning. Key factors that are associated with disability and these disorders in young people are social and economic participation (e.g. educa...
journal_title:BMC psychiatry
pub_type: 杂志文章,评审
doi:10.1186/s12888-016-0852-3
更新日期:2016-05-23 00:00:00
abstract:BACKGROUND:Despite the effectiveness of methylphenidate for treating ADHD, up to 30% of individuals with ADHD show poor responses to methylphenidate. Neuroimaging biomarkers to predict medication responses remain elusive. This study characterized neuroanatomical features that differentiated between clinically good and ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-021-03040-5
更新日期:2021-01-11 00:00:00
abstract:BACKGROUND:Increased mortality rates among previous child and adolescent psychiatry (CAP) patients have been found in Scandinavian studies up to the 1980s. The suicide risk in this group has been estimated to be almost five times higher than expected. This article addresses two questions: Do Swedish CAP patients contin...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-6-51
更新日期:2006-11-02 00:00:00
abstract:BACKGROUND:Despite increased interest in workplace mental health interventions, the evidence for beneficial effects is mixed. Furthermore, many existing studies lack methodological rigor. We report results from a group randomized control trial to test the efficacy of a vastly popular intervention in Canada, the Road to...
journal_title:BMC psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12888-019-2287-0
更新日期:2019-10-29 00:00:00
abstract:BACKGROUND:Koro is a culture bound syndrome, which has been reported usually from Asian countries. It has been described as an acute, brief lasting illness, which often occurs in epidemics. There is no description in literature of a chronic form of this syndrome. CASE PRESENTATION:Two sporadic cases with koro-like sym...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-5-34
更新日期:2005-10-12 00:00:00
abstract:BACKGROUND:Depressive and anxiety disorders are common in primary care setting but often remain undiagnosed. Metabolic syndrome (MetS) is also prevalent in the general population and can impair recognition of common mental disorders due to significant co-morbidity and overlap with psychiatric symptoms included in self-...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-017-1576-8
更新日期:2018-01-08 00:00:00
abstract:BACKGROUND:Ensuring equitable and timely access to Cognitive Behaviour Therapy (CBT) is challenging within Canada's service delivery model. The current study aims to determine acceptability and effectiveness of 4-session, large, Cognitive Behaviour Therapy with Mindfulness (CBTm) classes. METHODS:A retrospective chart...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-019-2124-5
更新日期:2019-05-03 00:00:00
abstract:BACKGROUND:The prevalence of smoking in patients with schizophrenia is higher than that in the general population and is an important medical issue. Short-term smoking cessation tends to worsen psychiatric symptoms in patients with schizophrenia but decreases sympathetic nervous system activity and improves plasma chol...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-017-1250-1
更新日期:2017-03-07 00:00:00
abstract:BACKGROUND:The suffering people experience following a first episode of psychosis is great, and has been well-investigated. Conversely, potential positive outcomes following a first episode of psychosis have been under-investigated. One such outcome that may result from a first episode of psychosis is posttraumatic gro...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-016-0977-4
更新日期:2016-07-25 00:00:00
abstract:BACKGROUND:Anxiety and related disorders are among the most common mental disorders, with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are under-diagnosed and under-treated. METHODS:These guidelines were developed by Canadian experts in anxiety and related disorders through a consens...
journal_title:BMC psychiatry
pub_type: 杂志文章,评审
doi:10.1186/1471-244X-14-S1-S1
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The polymorphism rs6313 (T102C) has been associated with suicidal behavior in case-control and meta-analysis studies, but results and conclusions remain controversial. The aim of the present study was to examine the association between T102C with suicidal behavior in a case-control study and, to assess the c...
journal_title:BMC psychiatry
pub_type: 杂志文章,meta分析
doi:10.1186/1471-244X-13-25
更新日期:2013-01-12 00:00:00
abstract:BACKGROUND:Child maltreatment poses a risk to children and adolescents' mental health and may also affect cognitive functioning. Also harsh discipline has been frequently associated with mental health problems. However, within societies in which harsh disciplinary methods are culturally normed and highly prevalent less...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-016-0828-3
更新日期:2016-04-29 00:00:00
abstract:BACKGROUND:No clear recommendations exist regarding which antipsychotic drug should be prescribed first for a patient suffering from psychosis. The primary aims of this naturalistic study were to assess the head-to-head effectiveness of first-line second-generation antipsychotics with regards to time until drug discont...
journal_title:BMC psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-244X-10-26
更新日期:2010-03-24 00:00:00
abstract:BACKGROUND:Past research on the association between insomnia and suicidal ideation (SI) has produced mixed findings. The current study explored the relationship between insomnia, SI, and past-year mental health status among a large Canadian Forces (CF) sample. METHOD:Data was obtained from the 2013 Canadian Forces Men...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-017-1372-5
更新日期:2017-06-06 00:00:00
abstract:BACKGROUND:In recent years, Voluntary Assisted Return Programmes (VARPs) have received increasing funding as a potential way of reducing the number of refugees in EU member states. A number of factors may affect the mental well-being of returnees. These include adjustment to the home country following return, difficult...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/1471-244X-8-88
更新日期:2008-11-10 00:00:00
abstract:BACKGROUND:There is a physical inactivity pandemic around the world despite the known benefits of engaging in physical activity. This is true for individuals who would receive notable benefits from physical activity, in particular those with mood disorders. In this study, we explored the factors that facilitate and imp...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-017-1476-y
更新日期:2017-08-31 00:00:00
abstract:BACKGROUND:Depression is an important public health problem and is closely associated with suicidal behavior in the population. Although the Center for Epidemiologic Studies Depression Scale (CES-D) is widely used for assessment of depression, the psychometric characteristics of this scale have not been explored in stu...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-015-0458-1
更新日期:2015-04-09 00:00:00
abstract:BACKGROUND:"Behaviour that Challenges" is common in people living with dementia, resident in care homes and historically has been treated with anti-psychotics. However, such usage is associated with 1800 potentially avoidable deaths annually in the UK. This study investigated the feasibility of a full clinical trial of...
journal_title:BMC psychiatry
pub_type: 临床试验,杂志文章
doi:10.1186/s12888-018-1907-4
更新日期:2018-10-19 00:00:00
abstract:BACKGROUND:Little is known regarding the association between adverse events (AEs) and psychiatric medications administered to pregnant women in clinical trials during the pre-marketing period. This study analyzes reports of AE association with psychiatric medication administrated during pregnancy using post-marketing s...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-02525-z
更新日期:2020-03-12 00:00:00
abstract:BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) have become the most frequently used antidepressants in China in recent decades. This systematic review and meta-analysis examined the efficacy and tolerability of SSRIs in Chinese studies and the quality of Chinese randomized controlled trials. METHODS:Major ...
journal_title:BMC psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12888-014-0245-4
更新日期:2014-08-27 00:00:00
abstract:BACKGROUND:The majority of people experiencing mental-health problems do not seek help, and the stigma of mental illness is considered a major barrier to seeking appropriate treatment. More targeted interventions (e.g. at the workplace) seem to be a promising and necessary supplement to public campaigns, but little is ...
journal_title:BMC psychiatry
pub_type: 杂志文章,评审
doi:10.1186/s12888-015-0706-4
更新日期:2016-01-06 00:00:00
abstract:BACKGROUND:Agitation is a common manifestation of bipolar disorder and schizophrenia which includes symptoms ranging from inner tension and unease to violence and aggression. Much of the existing literature has focused on agitation in the acute setting, with the patient experience poorly defined. Thus, the aim of this ...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-018-1673-3
更新日期:2018-04-16 00:00:00
abstract:BACKGROUND:Although the individual and economic disease burden of depression is particularly high for long-term symptoms, little is known of the lifetime course of chronic depression. Most evidence derives from clinical samples, and the diagnostic distinction between persistent depressive disorder (PDD) and non-chronic...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-2460-5
更新日期:2020-02-10 00:00:00
abstract:BACKGROUND:Exploration of the information and participation needs of psychiatric inpatients is an important step for the implementation of recovery-oriented mental health service. The objective of this study was to explore the information and participation needs of Chinese psychiatric inpatients in the largest psychiat...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-016-0959-6
更新日期:2016-07-12 00:00:00
abstract:BACKGROUND:To review the prevalence and impact of generalized anxiety disorder (GAD) below the diagnostic threshold and explore its treatment needs in times of scarce healthcare resources. METHODS:A systematic literature search was conducted until January 2013 using PUBMED/MEDLINE, PSYCINFO, EMBASE and reference lists...
journal_title:BMC psychiatry
pub_type: 杂志文章,评审
doi:10.1186/1471-244X-14-128
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Posttraumatic stress disorder (PTSD) can have long-term and far-reaching impacts on health and social and occupational functioning. This study examined factors associated with persistent PTSD among U.S. service members and veterans. METHODS:Using baseline and follow-up (2001-2013) questionnaire data collect...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-018-1590-5
更新日期:2018-02-17 00:00:00
abstract:BACKGROUND:Increasing numbers of programs are addressing the specific needs of homeless people with schizophrenia in terms of access to housing, healthcare, basic human rights and other domains. Although quality of life scales are being used to evaluate such programs, few instruments have been validated for people with...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-017-1227-0
更新日期:2017-02-17 00:00:00
abstract:BACKGROUND:Asverin® (tipepidine hibenzate) has been used as an antitussive for > 50 years in Japan. Studies revealed that tipepidine modulates monoamine levels, by inhibiting G-protein-activated inwardly rectifying potassium (GIRK) channels, expecting the potential therapeutic effects of tipepidine for attention-defici...
journal_title:BMC psychiatry
pub_type: 杂志文章
doi:10.1186/s12888-020-02932-2
更新日期:2020-11-10 00:00:00