Implication of human endogenous retrovirus envelope proteins in placental functions.

abstract：:Research on human enteroviruses has resulted in the identification of more than 100 enterovirus types, which use more than 10 protein receptors and/or attachment factors required in cell binding and initiation of the replication cycle. Many of these "viral" receptors are overexpressed in cancer cells. Receptor binding...

journal_title：Viruses

authors： Ylä-Pelto J,Tripathi L,Susi P

更新日期：2016-02-23 00:00:00

abstract：:Avian influenza virus (AIV) is a highly diverse and widespread poultry pathogen. Itsevolution and adaptation may be affected by multiple host and ecological factors, which are stillpoorly understood. In the present study, a turkey-origin H9N2 AIV was used as a model toinvestigate the within-host diversity of the virus...

journal_title：Viruses

authors： Świętoń E,Tarasiuk K,Olszewska-Tomczyk M,Iwan E,Śmietanka K

更新日期：2020-03-16 00:00:00

abstract：:The first discovered human retrovirus, Human T-Lymphotropic Virus type 1 (HTLV-1), is responsible for an aggressive form of T cell leukemia/lymphoma. Mouse models recapitulating the leukemogenesis process have been helpful for understanding the mechanisms underlying the pathogenesis of this retroviral-induced disease....

journal_title：Viruses

authors： Pérès E,Bagdassarian E,This S,Villaudy J,Rigal D,Gazzolo L,Duc Dodon M

更新日期：2015-12-07 00:00:00

abstract：:Non-human primates (NHP) are the only animal model suitable to evaluate the protection efficacy of HIV-1 vaccines. It is important to understand how and when neutralizing antibodies (nAbs) with specificities similar to those of human broadly neutralizing antibodies (bnAbs) develop in NHPs. To address these questions, ...

journal_title：Viruses

authors： Gao N,Gai Y,Meng L,Wang C,Zhang X,Wang W,Qin C,Yu X,Gao F

更新日期：2020-01-31 00:00:00

abstract：:Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance arises from mutation fixation in the viral genome during antiretroviral therapy. Primary mutations directly confer antiviral drug resistance, while secondary mutations arise that do not confer drug resistance. The A62V amino acid substitution in ...

journal_title：Viruses

authors： Maldonado JO,Mansky LM

更新日期：2018-07-19 00:00:00

abstract：:Begomoviruses are one of the major groups of plant viruses with an important economic impact on crop production in tropical and subtropical regions. The global spread of its polyphagous vector, the whitefly Bemisia tabaci, has contributed to the emergence and diversification of species within this genus. In this study...

journal_title：Viruses

authors： Romay G,Geraud-Pouey F,Chirinos DT,Mahillon M,Gillis A,Mahillon J,Bragard C

更新日期：2019-04-04 00:00:00

abstract：:Porcine endogenous retroviruses (PERVs) are integrated in the genome of pigs and are transmitted like cellular genes from parents to the offspring. Whereas PERV-A and PERV-B are present in all pigs, PERV-C was found to be in many, but not all pigs. When PERV-C is present, recombination with PERV-A may happen and the P...

journal_title：Viruses

authors： Krüger L,Stillfried M,Prinz C,Schröder V,Neubert LK,Denner J

更新日期：2020-04-08 00:00:00

abstract：:Human cytomegalovirus (HCMV) encodes a number of viral proteins with homology to cellular G protein-coupled receptors (GPCRs). These viral GPCRs, including US27, US28, UL33, and UL78, have been ascribed numerous functions during infection, including activating diverse cellular pathways, binding to immunomodulatory che...

journal_title：Viruses

authors： Noriega VM,Gardner TJ,Redmann V,Bongers G,Lira SA,Tortorella D

更新日期：2014-03-12 00:00:00

abstract：:Hematopoietic stem cell transplantation from anti-cytomegalovirus immunoglobulin G (anti-CMV-IgG) positive donors facilitated immunological recovery post-transplant, which may indicate that chronic CMV infection has an effect on the immune system. This can be seen in the recipients after reconstitution with donor lymp...

journal_title：Viruses

authors： Jaskula E,Dlubek D,Tarnowska A,Lange J,Mordak-Domagala M,Suchnicki K,Sedzimirska M,Borowik A,Mizia S,Lange A

更新日期：2015-03-23 00:00:00

abstract：:The human cytomegalovirus (HCMV)-encoded cyclin-dependent kinase (CDK) ortholog pUL97 associates with human cyclin B1 and other types of cyclins. Here, the question was addressed whether cyclin interaction of pUL97 and additional viral proteins is detectable by mass spectrometry-based approaches. Proteomic data were v...

journal_title：Viruses

authors： Steingruber M,Kraut A,Socher E,Sticht H,Reichel A,Stamminger T,Amin B,Couté Y,Hutterer C,Marschall M

更新日期：2016-08-18 00:00:00

abstract：:Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer than 5% of HBV-infected adults (but up to 90% of HBV-infected infants and children) develop chronic HBV infection as indicated by contin...

journal_title：Viruses

authors： Megahed FAK,Zhou X,Sun P

更新日期：2020-03-05 00:00:00

abstract：:Hepatitis A virus (HAV) infection is one of the major causes of acute hepatitis, and this infection occasionally causes acute liver failure. HAV infection is associated with HAV-contaminated food and water as well as sexual transmission among men who have sex with men. Although an HAV vaccine has been developed, outbr...

journal_title：Viruses

authors： Kanda T,Sasaki R,Masuzaki R,Matsumoto N,Ogawa M,Moriyama M

更新日期：2020-05-12 00:00:00

abstract：:The cell response to virus infection and virus perturbation of that response is dynamic and is reflected by changes in cell susceptibility to infection. In this study, we evaluated the response of human epithelial cells to sequential infections with human respiratory syncytial virus strains A2 and B to determine if a ...

journal_title：Viruses

authors： Simeonov I,Gong X,Kim O,Poss M,Chiaromonte F,Fricks J

更新日期：2010-12-01 00:00:00

abstract：:Peste des petits ruminants virus (PPRV) causes a contagious disease of high morbidity and mortality in global sheep and goat populations. To better control this disease and inform eradication strategies, an improved understanding of how PPRV transmission risk varies by age is needed. Our study used a piece-wise cataly...

journal_title：Viruses

authors： Herzog CM,de Glanville WA,Willett BJ,Cattadori IM,Kapur V,Hudson PJ,Buza J,Swai ES,Cleaveland S,Bjørnstad ON

更新日期：2020-02-07 00:00:00

abstract：:Extensive surveillance in bat populations in response to recent emerging diseases has revealed that this group of mammals acts as a reservoir for a large range of viruses. However, the oldest known association between a zoonotic virus and a bat is that between rabies virus and the vampire bat. Vampire bats are only fo...

journal_title：Viruses

authors： Johnson N,Aréchiga-Ceballos N,Aguilar-Setien A

更新日期：2014-04-29 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. The 3' untranslated region (UTR) of this β-CoV contains essential cis-acting RNA elements for the viral genome transcription and replication. These elements include an equilibrium between an extended bulged s...

journal_title：Viruses

authors： Zhao J,Qiu J,Aryal S,Hackett JL,Wang J

更新日期：2020-12-21 00:00:00

abstract：:Hepatitis C is a major global health burden with an estimated 160 million infected individuals worldwide. This long-term disease evolves slowly, often leading to chronicity and potentially to liver failure. There is no anti-HCV vaccine, and, until recently, the only treatment available, based on pegylated interferon a...

journal_title：Viruses

authors： Calland N,Dubuisson J,Rouillé Y,Séron K

更新日期：2012-10-17 00:00:00

abstract：:Two sister orders of the brown macroalgae (class Phaeophyceae), the morphologically complex Laminariales (commonly referred to as kelp) and the morphologically simple Ectocarpales are natural hosts for the dsDNA phaeoviruses (family Phycodnaviridae) that persist as proviruses in the genomes of their hosts. We have pre...

journal_title：Viruses

authors： McKeown DA,Schroeder JL,Stevens K,Peters AF,Sáez CA,Park J,Rothman MD,Bolton JJ,Brown MT,Schroeder DC

更新日期：2018-08-05 00:00:00

abstract：:Cucurbit yellow stunting disorder virus (CYSDV), a bipartite whitefly-transmitted virus, constitutes a major threat to commercial cucurbit production worldwide. Here, construction of full-length CYSDV RNA1 and RNA2 cDNA clones allowed the in vitro synthesis of RNA transcripts able to replicate in cucumber protoplasts....

journal_title：Viruses

authors： Owen CA,Moukarzel R,Huang X,Kassem MA,Eliasco E,Aranda MA,Coutts RH,Livieratos IC

更新日期：2016-06-14 00:00:00

abstract：:Interferon-inducible transmembrane proteins (IFITM1/2/3) have been reported to suppress the entry of a wide range of viruses. However, their antiviral functional residues and specific mechanisms are still unclear. Here, we firstly resolved the topology of IFITM1 on the plasma membrane where N-terminus points into the ...

journal_title：Viruses

authors： Sun F,Xia Z,Han Y,Gao M,Wang L,Wu Y,Sabatier JM,Miao L,Cao Z

更新日期：2020-03-08 00:00:00

abstract：:During infection, Citrus tristeza virus (CTV) produces a non-coding subgenomic RNA referred to as low-molecular-weight tristeza 1 (LMT1), which for a long time has been considered as a by-product of the complex CTV replication machinery. In this study, we investigated the role of LMT1 in the virus infection cycle usin...

journal_title：Viruses

authors： Kang SH,Sun YD,Atallah OO,Huguet-Tapia JC,Noble JD,Folimonova SY

更新日期：2019-05-14 00:00:00

abstract：:Samples of two Ageratum conyzoides, one Sonchus oleraceus and one turnip (Brassica rapa var. rapa) exhibiting virus-like symptoms were collected from Pakistan and Nepal. Full-length begomovirus clones were obtained from the four plant samples and betasatellite clones from three of these. The begomovirus sequences were...

journal_title：Viruses

authors： Tahir M,Amin I,Haider MS,Mansoor S,Briddon RW

更新日期：2015-02-10 00:00:00

abstract：:Feline immunodeficiency virus (FIV) is widespread in feline populations and causes an AIDS-like illness in domestic cats. It is highly prevalent in several endangered feline species. In domestic cats FIV infection is a valuable small animal model for HIV infection. In recent years there has been sa significant increas...

journal_title：Viruses

authors： Kenyon JC,Lever AM

更新日期：2011-11-01 00:00:00

abstract：:Flaviviruses, most of which are emerging and re-emerging human pathogens and significant public health concerns worldwide, are positive-sense RNA viruses. Flavivirus replication occurs on the ER and is regulated by many mechanisms and factors. NS5, which consists of a C-terminal RdRp domain and an N-terminal methyltra...

journal_title：Viruses

authors： Duan Y,Zeng M,Jiang B,Zhang W,Wang M,Jia R,Zhu D,Liu M,Zhao X,Yang Q,Wu Y,Zhang S,Liu Y,Zhang L,Yu Y,Pan L,Chen S,Cheng A

更新日期：2019-10-10 00:00:00

abstract：:Cotton leaf curl disease (CLCuD) is one of the most economically important diseases and is a constraint to cotton production in major producers, Pakistan and India. CLCuD is caused by monopartite plant viruses belonging to the family Geminiviridae (genus Begomovirus), in association with an essential, disease-specific...

journal_title：Viruses

authors： Zubair M,Zaidi SS,Shakir S,Amin I,Mansoor S

更新日期：2017-09-29 00:00:00

abstract：:We previously characterized a carbohydrate binding protein, Gp047, derived from lytic Campylobacter phage NCTC 12673, as a promising diagnostic tool for the identification of Campylobacter jejuni and Campylobacter coli. We also demonstrated that this protein binds specifically to acetamidino-modified pseudaminic acid ...

journal_title：Viruses

authors： Javed MA,Sacher JC,van Alphen LB,Patry RT,Szymanski CM

更新日期：2015-12-16 00:00:00

abstract：:Peste des Petits Ruminants (PPR) is a highly infectious disease caused by a virus of the Morbillivirus genus. The current PPR eradication effort relies mainly on the implementation of massive vaccination campaigns. One of the most widely used PPR vaccines is the Nigeria 75/1 strain obtained after attenuation by 75 ser...

journal_title：Viruses

authors： Eloiflin RJ,Boyer M,Kwiatek O,Guendouz S,Loire E,Servan de Almeida R,Libeau G,Bataille A

更新日期：2019-08-07 00:00:00

abstract：:Mycoviruses appear to be widespread in Fusarium species worldwide. The aim of this work was to identify mycoviral infections in Fusarium spp., isolated from maize and sorghum grown in Argentina, and to estimate their potential effects on the pathogenicity and toxigenesis of the host fungus towards maize. Mycoviruses w...

journal_title：Viruses

authors： Jacquat AG,Theumer MG,Cañizares MC,Debat HJ,Iglesias J,García Pedrajas MD,Dambolena JS

更新日期：2020-10-14 00:00:00

abstract：:Streptococcus thermophilus is considered one of the most important species for the dairy industry. Due to their diffusion in dairy environments, bacteriophages can represent a threat to this widely used bacterial species. Despite the presence of a CRISPR-Cas system in the S. thermophilus genome, some lysogenic strains...

journal_title：Viruses

authors： da Silva Duarte V,Giaretta S,Campanaro S,Treu L,Armani A,Tarrah A,Oliveira de Paula S,Giacomini A,Corich V

更新日期：2018-12-22 00:00:00

abstract：:Many blood-feeding arthropods are known vectors of viruses that are a source of unprecedented global health concern. Mosquitoes are an integral part of these arthropod vectors. Advancements in next-generation sequencing and bioinformatics has expanded our knowledge on the richness of viruses harbored by arthropods. In...

journal_title：Viruses

authors： Atoni E,Wang Y,Karungu S,Waruhiu C,Zohaib A,Obanda V,Agwanda B,Mutua M,Xia H,Yuan Z

更新日期：2018-01-12 00:00:00