Cesarean section and rate of subsequent stillbirth, miscarriage, and ectopic pregnancy: a Danish register-based cohort study.

abstract：BACKGROUND:Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic antiretrovirals to a treatment ...

journal_title：PLoS medicine

authors： Mocroft A,Lundgren JD,Ross M,Law M,Reiss P,Kirk O,Smith C,Wentworth D,Neuhaus J,Fux CA,Moranne O,Morlat P,Johnson MA,Ryom L,D:A:D study group.,Royal Free Hospital Clinic Cohort.,INSIGHT study group.,SMART study group.,

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:There is growing concern that racial and ethnic minority communities around the world are experiencing a disproportionate burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19). We investigated racial and ethnic disparities in patterns of COVI...

journal_title：PLoS medicine

authors： Rentsch CT,Kidwai-Khan F,Tate JP,Park LS,King JT Jr,Skanderson M,Hauser RG,Schultze A,Jarvis CI,Holodniy M,Lo Re V 3rd,Akgün KM,Crothers K,Taddei TH,Freiberg MS,Justice AC

更新日期：2020-09-22 00:00:00

abstract：BACKGROUND:Clinical trials of interventions designed to prevent severe falciparum malaria in children require a clear endpoint. The internationally accepted definition of severe malaria is sensitive, and appropriate for clinical purposes. However, this definition includes individuals with severe nonmalarial disease and...

journal_title：PLoS medicine

authors： Bejon P,Berkley JA,Mwangi T,Ogada E,Mwangi I,Maitland K,Williams T,Scott JA,English M,Lowe BS,Peshu N,Newton CR,Marsh K

更新日期：2007-08-01 00:00:00

abstract：:Chris Beyrer and colleagues reflect on an underappreciated trend in multiple African, Asian, and Caribbean settings, in which the provision of HIV and other essential health services for sexual and gender minorities is expanding despite challenging legal and social environments. ...

journal_title：PLoS medicine

authors： Beyrer C,Makofane K,Orazulike I,Diouf D,Baral SD

更新日期：2016-10-25 00:00:00

abstract：:In this month's editorial, PLOS Medicine's Chief Editor Larry Peiperl discusses the relevance of patient care to a journal editor's work. ...

journal_title：PLoS medicine

authors： Peiperl L,PLOS Medicine Editors.

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and excessive accumulation of extracellular matrix in the lung. METHODS AND FINDINGS:Using oligonucleotide arrays, we identified osteopontin as one of the genes that significantly distinguishes IPF f...

journal_title：PLoS medicine

authors： Pardo A,Gibson K,Cisneros J,Richards TJ,Yang Y,Becerril C,Yousem S,Herrera I,Ruiz V,Selman M,Kaminski N

更新日期：2005-09-01 00:00:00

abstract：:Andrew Seale and colleagues discuss the development of a global strategy to counter sexually transmitted infections. ...

journal_title：PLoS medicine

authors： Seale A,Broutet N,Narasimhan M

更新日期：2017-06-27 00:00:00

abstract：BACKGROUND:There is evidence that a young child's risk of dying increases following the mother's death, but little is known about the risk when the mother becomes very ill prior to her death. We hypothesized that children would be more likely to die during the period several months before their mother's death, as well ...

journal_title：PLoS medicine

authors： Clark SJ,Kahn K,Houle B,Arteche A,Collinson MA,Tollman SM,Stein A

更新日期：2013-01-01 00:00:00

abstract：:Drawing upon interviews with experts and a review of the literature, Gavin Yamey proposes a new framework for scaling up global health interventions. ...

journal_title：PLoS medicine

authors： Yamey G

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Malaysia's stable health care system is facing challenges with increasing medicine costs. To investigate these issues a survey was carried out to evaluate medicine prices, availability, affordability, and the structure of price components. METHODS AND FINDINGS:The methodology developed by the World Health O...

journal_title：PLoS medicine

authors： Babar ZU,Ibrahim MI,Singh H,Bukahri NI,Creese A

更新日期：2007-03-27 00:00:00

abstract：BACKGROUND:This paper examines the efforts of consultants affiliated with Philip Morris (PM), the world's leading transnational tobacco corporation, to influence scientific research and training in Thailand via the Chulabhorn Research Institute (CRI). A leading Southeast Asian institute for environmental health science...

journal_title：PLoS medicine

authors： Mackenzie R,Collin J

更新日期：2008-12-23 00:00:00

abstract：BACKGROUND:agricultural pesticide poisoning is a major public health problem in the developing world, killing at least 250,000-370,000 people each year. Targeted pesticide restrictions in Sri Lanka over the last 20 years have reduced pesticide deaths by 50% without decreasing agricultural output. However, regulatory de...

journal_title：PLoS medicine

authors： Dawson AH,Eddleston M,Senarathna L,Mohamed F,Gawarammana I,Bowe SJ,Manuweera G,Buckley NA

更新日期：2010-10-26 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are essential in host defense against pathogens by virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as the most important receptor for gram-positive bacteria, while TLR4 is regarded as the gram-negative TLR. Melioidosis is a severe infectio...

journal_title：PLoS medicine

authors： Wiersinga WJ,Wieland CW,Dessing MC,Chantratita N,Cheng AC,Limmathurotsakul D,Chierakul W,Leendertse M,Florquin S,de Vos AF,White N,Dondorp AM,Day NP,Peacock SJ,van der Poll T

更新日期：2007-07-31 00:00:00

abstract：BACKGROUND:Violence against women by intimate partners remains unacceptably common worldwide. The evidence base for the assumed psychological impacts of intimate partner violence (IPV) is derived primarily from studies conducted in high-income countries. A recently published systematic review identified 13 studies link...

journal_title：PLoS medicine

authors： Tsai AC,Tomlinson M,Comulada WS,Rotheram-Borus MJ

更新日期：2016-01-19 00:00:00

abstract：BACKGROUND:Outbreaks of emerging infectious diseases, especially those of a global nature, require rapid epidemiological analysis and information dissemination. The final products of those activities usually comprise internal memoranda and briefs within public health authorities and original research published in peer-...

journal_title：PLoS medicine

authors： Xing W,Hejblum G,Leung GM,Valleron AJ

更新日期：2010-05-04 00:00:00

abstract：:Financial risk protection is a key component of universal health coverage (UHC), which is defined as access to all needed quality health services without financial hardship. As part of the PLOS Medicine Collection on measurement of UHC, the aim of this paper is to examine and to compare and contrast existing measures ...

journal_title：PLoS medicine

authors： Saksena P,Hsu J,Evans DB

更新日期：2014-09-22 00:00:00

abstract：BACKGROUND:Identifying stage II patients with colorectal cancer (CRC) at higher risk of progression is a clinical priority in order to optimize the advantages of adjuvant chemotherapy while avoiding unnecessary toxicity. Recently, the intensity and the quality of the host immune response in the tumor microenvironment h...

journal_title：PLoS medicine

authors： Sanz-Pamplona R,Melas M,Maoz A,Schmit SL,Rennert H,Lejbkowicz F,Greenson JK,Sanjuan X,Lopez-Zambrano M,Alonso MH,Qu C,McDonnell KJ,Idos GE,Vignali M,Emerson R,Fields P,Guinó E,Santos C,Salazar R,Robins HS,Rennert

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:Meta-analyses of antidepressant medications have reported only modest benefits over placebo treatment, and when unpublished trial data are included, the benefit falls below accepted criteria for clinical significance. Yet, the efficacy of the antidepressants may also depend on the severity of initial depress...

journal_title：PLoS medicine

authors： Kirsch I,Deacon BJ,Huedo-Medina TB,Scoboria A,Moore TJ,Johnson BT

更新日期：2008-02-01 00:00:00

abstract：:This month in PLOS Medicine we launched a Special Issue on New Tools and Strategies for Tuberculosis Diagnosis, Care, and Elimination. In this issue's Editorial, the Guest Editors Claudia Denkinger, Richard Chaisson, and Mark Hatherill highlight some of the research that will publish and how these studies focusing on ...

journal_title：PLoS medicine

authors： Hatherill M,Chaisson RE,Denkinger CM

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND:Annual influenza vaccination of institutional health care workers (HCWs) is advised in most Western countries, but adherence to this recommendation is generally low. Although protective effects of this intervention for nursing home patients have been demonstrated in some clinical trials, the exact relationsh...

journal_title：PLoS medicine

authors： van den Dool C,Bonten MJ,Hak E,Heijne JC,Wallinga J

更新日期：2008-10-28 00:00:00

abstract：BACKGROUND:Introduction of pneumococcal conjugate vaccines (PCVs) of limited valency is justified in Africa by the high burden of pneumococcal disease. Long-term beneficial effects of PCVs may be countered by serotype replacement. We aimed to determine the impact of PCV-7 vaccination on pneumococcal carriage in rural G...

journal_title：PLoS medicine

authors： Roca A,Hill PC,Townend J,Egere U,Antonio M,Bojang A,Akisanya A,Litchfield T,Nsekpong DE,Oluwalana C,Howie SR,Greenwood B,Adegbola RA

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Electronic medical records provide large-scale real-world clinical data for use in developing clinical decision systems. However, sophisticated methodology and analytical skills are required to handle the large-scale datasets necessary for the optimisation of prediction accuracy. Myopia is a common cause of ...

journal_title：PLoS medicine

authors： Lin H,Long E,Ding X,Diao H,Chen Z,Liu R,Huang J,Cai J,Xu S,Zhang X,Wang D,Chen K,Yu T,Wu D,Zhao X,Liu Z,Wu X,Jiang Y,Yang X,Cui D,Liu W,Zheng Y,Luo L,Wang H,Chan CC,Morgan IG,He M,Liu Y

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Although it has long been appreciated that ovarian carcinoma subtypes (serous, clear cell, endometrioid, and mucinous) are associated with different natural histories, most ovarian carcinoma biomarker studies and current treatment protocols for women with this disease are not subtype specific. With the emerg...

journal_title：PLoS medicine

authors： Köbel M,Kalloger SE,Boyd N,McKinney S,Mehl E,Palmer C,Leung S,Bowen NJ,Ionescu DN,Rajput A,Prentice LM,Miller D,Santos J,Swenerton K,Gilks CB,Huntsman D

更新日期：2008-12-02 00:00:00

abstract：BACKGROUND:The disease burden attributable to mental health problems and to excess or harmful alcohol use is considerable. Despite a strong relationship between these 2 important factors in population health, there are few studies quantifying the mortality risk associated with their co-occurrence in the general populat...

journal_title：PLoS medicine

authors： Degerud E,Høiseth G,Mørland J,Ariansen I,Graff-Iversen S,Ystrom E,Zuccolo L,Næss Ø

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Ovarian cancer kills approximately 15,000 women in the United States every year, and more than 140,000 women worldwide. Most deaths from ovarian cancer are caused by tumors of the serous histological type, which are rarely diagnosed before the cancer has spread. Rational design of a potentially life-saving e...

journal_title：PLoS medicine

authors： Brown PO,Palmer C

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Animal studies suggest vital roles of sphingolipids, especially ceramides, in the pathogenesis of type 2 diabetes (T2D) via pathways involved in insulin resistance, β-cell dysfunction, and inflammation, but human studies are limited. We aimed to evaluate the associations of circulating sphingolipids with inc...

journal_title：PLoS medicine

authors： Yun H,Sun L,Wu Q,Zong G,Qi Q,Li H,Zheng H,Zeng R,Liang L,Lin X

更新日期：2020-12-09 00:00:00

abstract：:Martin Gerdin and colleagues argue that disaster health interventions and decision-making can benefit from an evidence-based approach Please see later in the article for the Editors' Summary. ...

journal_title：PLoS medicine

authors： Gerdin M,Clarke M,Allen C,Kayabu B,Summerskill W,Devane D,MacLachlan M,Spiegel P,Ghosh A,Zachariah R,Gupta S,Barbour V,Murray V,von Schreeb J

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:Epidemiological studies have provided compelling evidence of associations between ambient temperature and cardiovascular disease. However, evidence of effects of daily temperature variability on cardiovascular disease is scarce and mixed. We aimed to examine short-term associations between temperature variab...

journal_title：PLoS medicine

authors： Tian Y,Liu H,Si Y,Cao Y,Song J,Li M,Wu Y,Wang X,Xiang X,Juan J,Chen L,Wei C,Gao P,Hu Y

更新日期：2019-01-28 00:00:00

abstract：BACKGROUND:Intimate partner violence (IPV) against women is a major global health issue, particularly in low- and middle-income countries (LMICs), that is associated with poor physical and mental health, but its association with breastfeeding practices is understudied. Both the World Health Organization (WHO) and the U...

journal_title：PLoS medicine

authors： Caleyachetty R,Uthman OA,Bekele HN,Martín-Cañavate R,Marais D,Coles J,Steele B,Uauy R,Koniz-Booher P

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) is estimated to affect 130-180 million people worldwide. Although its origin is unknown, patterns of viral diversity suggest that HCV genotype 1 probably originated from West Africa. Previous attempts to estimate the spatiotemporal parameters of the virus, both globally and regionally...

journal_title：PLoS medicine

authors： Magiorkinis G,Magiorkinis E,Paraskevis D,Ho SY,Shapiro B,Pybus OG,Allain JP,Hatzakis A

更新日期：2009-12-01 00:00:00