Abstract:
:Although invariant natural killer T (iNKT) cells influence antitumor responses indirectly by secreting cytokines and promoting the cytolytic functions of T and NK cells, we find that iNKT cells mediate direct tumoricidal activity in vitro and significantly inhibit tumor growth in vivo, even in the absence of other cytotoxic lymphocytes.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Bassiri H,Das R,Nichols KEdoi
10.4161/onci.27440subject
Has Abstractpub_date
2013-12-01 00:00:00pages
e27440issue
12eissn
2162-4011issn
2162-402Xpii
2013ONCOIMM0350journal_volume
2pub_type
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