Abstract:
:Interleukin-10 (IL-10) is a potent immunomodulatory cytokine, whose cellular targets have not yet been precisely identified. Dendritic cell (DC)-specific IL-10 receptor knockout mice exhibit exaggerated T-cell reactivation in the skin, highlighting a key role of DCs in the maintenance of local immune homeostasis, beyond their classical function as regulators of T-cell priming in lymph nodes.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Clausen BE,Girard-Madoux MJdoi
10.4161/onci.23186subject
Has Abstractpub_date
2013-03-01 00:00:00pages
e23186issue
3eissn
2162-4011issn
2162-402Xpii
2012ONCOIMM0393journal_volume
2pub_type
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