Abstract：
BACKGROUND:Dicistroviridae is a new family of small, non-enveloped, +ssRNA viruses pathogenic to both beneficial arthropods and insect pests. Little is known about the dicistrovirus replication mechanism or gene function, and any knowledge on these subjects comes mainly from comparisons with mammalian viruses from the Picornaviridae family. Due to its peculiar genome organization and characteristics of the per os viral transmission route, dicistroviruses make good candidates for use as biopesticides. Triatoma virus (TrV) is a pathogen of Triatoma infestans (Hemiptera: Reduviidae), one of the main vectors of the human trypanosomiasis disease called Chagas disease. TrV was postulated as a potential control agent against Chagas' vectors. Although there is no evidence that TrV nor other dicistroviruses replicate in species outside the Insecta class, the innocuousness of these viruses in humans and animals needs to be ascertained. METHODS:In this study, RT-PCR and ELISA were used to detect the infectivity of this virus in Mus musculus BALB/c mice. RESULTS:In this study we have observed that there is no significant difference in the ratio IgG2a/IgG1 in sera from animals inoculated with TrV when compared with non-inoculated animals or mice inoculated only with non-infective TrV protein capsids. CONCLUSIONS:We conclude that, under our experimental conditions, TrV is unable to replicate in mice. This study constitutes the first test to evaluate the infectivity of a dicistrovirus in a vertebrate animal model.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Querido JF,Agirre J,Marti GA,Guérin DM,Silva MSdoi
10.1186/1756-3305-6-66subject
Has Abstractpub_date
2013-03-15 00:00:00pages
66issn
1756-3305pii
1756-3305-6-66journal_volume
6pub_type
杂志文章abstract：BACKGROUND:The spread of vector-borne diseases to new regions has become a global threat due to climate change, increasing traffic, and movement of people and animals. Dirofilaria repens, the canine subcutaneous filarioid nematode, has expanded its distribution range northward during the last decades. The northernmost ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2499-4
更新日期：2017-11-10 00:00:00
abstract：BACKGROUND:To reveal the spatio-temporal distribution of malaria vectors in the national malaria surveillance sites from 2005 to 2010 and provide reference for the current National Malaria Elimination Programme (NMEP) in China. METHODS:A 6-year longitudinal surveillance on density of malaria vectors was carried out in...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0741-5
更新日期：2015-03-07 00:00:00
abstract：BACKGROUND:More effective mosquito control strategies are urgently required due to the increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the release of insects carrying a dominant lethal allele (RIDL) are two proposed methods for environmentally-friendly, species-targeted populatio...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1331-x
更新日期：2016-01-28 00:00:00
abstract：BACKGROUND:Dirofilaria immitis is a mosquito-borne pathogen that is spreading worldwide, and the associated infection (i.e. dirofilariosis) is becoming a threat to animals and humans living in endemic areas. Little is known about the occurrence and risk of infection of D. immitis in pinnipeds. Here we report dirofilari...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2073-0
更新日期：2017-03-13 00:00:00
abstract：BACKGROUND:The strongylid nematode Haemonchus contortus is a parasite of major concern for modern livestock husbandry because hostile environmental conditions may induce diapause in the early fourth-stage larvae. METHODS:A new gene Hc-daf-22 was identified which is the homologue of Ce-daf-22 and human SCPx. Genome wal...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1704-1
更新日期：2016-07-29 00:00:00
abstract：BACKGROUND:Pyrenean chamois (Rupicapra pyrenaica pyrenaica) is a nearly monomorphic mountain ungulate with an unbiased sex-specific overwinter adult survival. Few differences in gastrointestinal parasitism have been reported by coprology as yet. This study aims to assess diversity, prevalence, intensity of infection an...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0774-9
更新日期：2015-03-18 00:00:00
abstract：BACKGROUND:Genetic information for Toxoplasma gondii isolates from pigs in eastern, south, and southwestern regions of China has been reported previously. However, there are no data from pigs in the northeastern area of the country. To better understand the epidemiology of T. gondii, we determined the seroprevalence an...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1525-2
更新日期：2016-04-29 00:00:00
abstract：BACKGROUND:Culex quinquefasciatus is a hematophagous insect from the Culicidae family that feeds on the blood of humans, dogs, birds and livestock. This species transmits a wide variety of pathogens between humans and animals. The midgut environment is the first location of pathogen-vector interactions for blood-feedin...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0985-0
更新日期：2015-07-16 00:00:00
abstract：BACKGROUND:Canine vector-borne diseases (CVBDs) are caused by a wide range of pathogens transmitted to dogs by arthropods including ticks and insects. Many CVBD-agents are of zoonotic concern, with dogs potentially serving as reservoirs and sentinels for human infections. The present study aimed at assessing the seropr...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-62
更新日期：2012-03-27 00:00:00
abstract：BACKGROUND:Understanding the biology of malaria vector mosquitoes is crucial to understanding many aspects of the disease, including control and future outcomes. The development rates and survival of two Afrotropical malaria vectors, Anopheles arabiensis and Anopheles funestus, are investigated here under conditions of...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-104
更新日期：2013-04-16 00:00:00
abstract：BACKGROUND:Insect-borne diseases could induce severe symptoms in human and clinical signs in animals, such as febrility, erythra, arthralgia and hemorrhagic fever, and cause significant economic losses and pose public health threat all over the world. The significant advantages of Luminex xMAP technology are high-throu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2996-0
更新日期：2018-07-31 00:00:00
abstract：BACKGROUND:Canine dirofilariasis due to Dirofilaria immitis is known to be endemic in continental Portugal. However, information about the transmitting mosquito species is still scarce, with only Culex theileri identified to date, albeit with L1-2, through dissection. This study was carried out to investigate the poten...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0760-2
更新日期：2015-03-03 00:00:00
abstract：BACKGROUND:Aedes mosquito-transmitted outbreaks of dengue and yellow fever have been reported from rural and urban parts of Côte d'Ivoire. The present study aimed at assessing Aedes spp. oviposition ecology in variously urbanized settings within arbovirus foci in southeastern Côte d'Ivoire. METHODS:Aedes spp. eggs wer...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1778-9
更新日期：2016-09-29 00:00:00
abstract：BACKGROUND:Canine monocytic ehrlichiosis (CME) is a tick-borne disease with a global distribution, caused by Ehrlichia canis. The inflammatory response to E. canis infection includes changes in certain acute phase proteins (APP) and in biomarkers of the oxidative status. APP responses are considered part of the innate ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0798-1
更新日期：2015-03-23 00:00:00
abstract：BACKGROUND:Plague, a zoonosis caused by Yersinia pestis, is found in Asia, the Americas but mainly in Africa, with the island of Madagascar reporting almost one third of human cases worldwide. In the highlands of Madagascar, plague is transmitted predominantly by two flea species which coexist on the island, but differ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1366-z
更新日期：2016-02-11 00:00:00
abstract：BACKGROUND:The invasive temperate mosquito Aedes japonicus japonicus is a potential vector for various infectious diseases and therefore a target of vector control measures. Even though established in Germany, it is unclear whether the species has already reached its full distribution potential. The possible range of t...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3366-2
更新日期：2019-03-25 00:00:00
abstract：BACKGROUND:The Anopheles gambiae Giles complex is the most widely studied and the most important insect vector group. We explored the use of the palp ratio method as a field tool to identify A. melas and A. gambiae in Ghana. METHODS:Human landing catches were conducted to collect mosquitoes in the coastal area of West...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0913-3
更新日期：2015-05-28 00:00:00
abstract：BACKGROUND:Alternative splicing (AS) of mRNA is a vital mechanism for enhancing genomic complexity in eukaryotes. Spliced isoforms of the same gene can have diverse molecular and biological functions and are often differentially expressed across various tissues, times, and conditions. Thus, AS has important implication...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-151
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Rhipicephalus microplus is a hard tick that has a major impact on cattle health in tropical and subtropical regions because it feeds on cattle and is implicated in the transmission of pathogens that cause diseases such as bovine anaplasmosis and babesiosis. Presently, acaricides are used to control tick infe...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2081-0
更新日期：2017-03-23 00:00:00
abstract：BACKGROUND:Lymphatic filariasis (LF) is a mosquito-borne parasitic disease and a major cause of disability worldwide. It is one of the neglected tropical diseases identified by the World Health Organization for elimination as a public health problem by 2020. Maps displaying disease distribution are helpful tools to ide...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3097-9
更新日期：2018-09-17 00:00:00
abstract：BACKGROUND:Leishmaniasis is a major parasitic disease worldwide, except in Australia and Antarctica, and it poses a significant public health problem. Due to the absence of safe and effective vaccines and drugs, researchers have begun an extensive search for new drugs. The aim of the current study was to investigate th...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04543-y
更新日期：2021-01-11 00:00:00
abstract：BACKGROUND:Co-infections of multiple parasite species in hosts may lead to interspecific associations and subsequently shape the structure of a parasite community. However, few studies have focused on these associations in highly abundant parasite species or, in particular, investigated how the associations develop wit...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-85
更新日期：2011-05-20 00:00:00
abstract：BACKGROUND:Dengue virus (DENV) is the arbovirus with the highest incidence in New Caledonia and in the South Pacific region. In 2012-2014, a major DENV-1 outbreak occurred in New Caledonia. The only known vector of DENV in New Caledonia is Aedes aegypti but no study has yet evaluated the competence of New Caledonia Ae....
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2319-x
更新日期：2017-08-09 00:00:00
abstract：BACKGROUND:Ixodes ricinus constitutes the main European vector tick for the Lyme borreliosis pathogen Borrelia burgdorferi (sensu lato), the relapsing fever borrelia Borrelia miyamotoi, as well as Anaplasma phagocytophilum and several Rickettsia species. Under laboratory conditions, a transovarial transmission to the n...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04049-7
更新日期：2020-04-07 00:00:00
abstract：BACKGROUND:The protistan pathogens Cryptosporidium and Giardia can cause significant intestinal diseases in animals and humans. Cattle, particularly calves, carrying these protists can be significant reservoirs for human infections and disease. However, little is known about the genetic make-up of Cryptosporidium and G...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2463-3
更新日期：2017-10-25 00:00:00
abstract：BACKGROUND:Air-borne introduction of exotic mosquitoes to Schiphol airport in the Netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011. Beginning in 2013, surveillance efforts at Schiphol had focused on promptly detecting accidental introductions at t...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2555-0
更新日期：2017-12-08 00:00:00
abstract：BACKGROUND:Accurate diagnosis of urogenital schistosomiasis is vital for surveillance/control programs. Amplification of schistosome DNA in urine by PCR is sensitive and specific but requires infrastructure, financial resources and skilled personnel, often not available in endemic areas. Recombinase Polymerase Amplific...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1055-3
更新日期：2015-09-04 00:00:00
abstract：BACKGROUND:Emerging resistance of heartworms (Dirofilaria immitis) to macrocyclic lactone (ML) preventives is an increasing concern for veterinarians, pet owners and animal health companies that supply heartworm preventives, with recent reports of resistant isolates identified from the Mississippi Delta region of the U...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2430-z
更新日期：2017-11-09 00:00:00
abstract：BACKGROUND:The ability of blood-feeding arthropods to successfully acquire and transmit pathogens of medical and veterinary importance has been shown to be interfered with, or enhanced by, the arthropod's native microbiome. Mosquitoes transmit viruses, protozoan and filarial nematodes, the majority of which contribute ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04218-8
更新日期：2020-07-13 00:00:00
abstract：BACKGROUND:Hepatocellular carcinoma-associated antigen 59 (HCA59), which is one of the most important excretory/secretory products of Haemonchus contortus (HcESPs), is known to have antigenic functions. However, its immunomodulatory effects on host cells are poorly understood. METHODS:Here, we cloned the HCA59 gene an...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3375-1
更新日期：2019-03-14 00:00:00
