Abstract：
BACKGROUND:Pertussis is a reported vaccine-preventable respiratory disease in China. Because the routine laboratory methods for diagnosis are not in use, the reported cases are mainly in infants with classical paroxysmal cough and the true incidence related to pertussis is most likely under estimated. In China, however, few studies have attempted to address this issue. The purpose of this cross sectional study was to estimate the incidence rates using the method of sero-epidemiology of immunoglobulin (Ig) G antibodies against pertussis toxin (PT) among healthy populations in China. METHODS:Blood samples were obtained from 1313 healthy individuals aged 0 to 95 years in Guangdong province of China throughout September 2010. Serum IgG antibodies against PT were determined by commercial ELISA kits. Subjects with concentration of anti-PT IgG higher than 30 IU/mL were indicated to have recent Bordetella pertussis infection, if they have not received a booster dose of pertussis vaccine within one year. RESULTS:Of the 1313 study subjects, 117 (8.91%) were found to have anti-PT antibodies higher than 30 IU/mL. The estimated incidence of recent infection was thus 9395 per 100,000 for individuals older than 7 years. Peaks of the estimated incidence rate of recent infection were found to be 11561 per 100,000 in age group of 41-50 years and 11428 per 100,000 in the group aged 13-19 years. CONCLUSIONS:Our study indicated that B.pertussis infections are considerablely common, particularly in adolescents and adults in China. The study also stresses the importance of laboratory diagnosis for pertussis and employment of booster dose of pertussis vaccine in adolescents and adults in this country.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Zhang Q,Zheng H,Liu M,Han K,Shu J,Wu C,Xu N,He Q,Luo Hdoi
10.1186/1471-2334-12-138subject
Has Abstractpub_date
2012-06-20 00:00:00pages
138issn
1471-2334pii
1471-2334-12-138journal_volume
12pub_type
杂志文章abstract：BACKGROUND:Nosocomial infection diagnosis in the intensive care unit (ICU) remains a challenge. We compared routine measurements of procalcitonin (PCT), C-reactive protein (CRP), white blood cell count (WBC) and temperature in the detection of ICU-acquired infections. METHOD:Prospective observational cohort study in a...
journal_title：BMC infectious diseases
pub_type： 杂志文章
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更新日期：2013-04-02 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-015-1287-z
更新日期：2015-12-02 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章,评审
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更新日期：2020-02-04 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
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更新日期：2017-07-26 00:00:00
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journal_title：BMC infectious diseases
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更新日期：2006-12-29 00:00:00
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journal_title：BMC infectious diseases
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doi：10.1186/s12879-015-1049-y
更新日期：2015-07-30 00:00:00
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更新日期：2018-11-07 00:00:00
abstract：BACKGROUND:Relapse of tuberculosis (TB) may develop as the result of reactivation of the endogenous primary infection, or as a result of a exogenous reinfection. This survey evaluated the rate of reactivation versus recent transmission among Iranian and Afghan relapse cases. METHODS:The sputum specimens were digested,...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-8-109
更新日期：2008-08-06 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章,随机对照试验
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更新日期：2009-01-17 00:00:00
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journal_title：BMC infectious diseases
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doi：10.1186/1471-2334-10-282
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-016-1909-0
更新日期：2016-10-19 00:00:00
abstract：BACKGROUND:Acute respiratory tract infections (ARTI) are an important public health problem. Improved identification of risk factors might enable targeted intervention. Therefore we carried out a case-control study with the aim of identifying environmental risk factors for ARTI consultations in the Dutch general popula...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-7-35
更新日期：2007-04-27 00:00:00
abstract：BACKGROUND:Men who have sex with men (MSM) bear a high burden of syphilis infection. Expanding syphilis testing to improve timely diagnosis and treatment is critical to improve syphilis control. However, syphilis testing rates remain low among MSM, particularly in low- and middle-income countries. We describe the proto...
journal_title：BMC infectious diseases
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12879-020-05188-z
更新日期：2020-06-29 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-05090-8
更新日期：2020-05-29 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-8-15
更新日期：2008-02-07 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4633-8
更新日期：2019-11-27 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-7-96
更新日期：2007-08-16 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-6-115
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-9-14
更新日期：2009-02-09 00:00:00
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journal_title：BMC infectious diseases
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doi：10.1186/1471-2334-13-432
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更新日期：2017-02-17 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-017-2234-y
更新日期：2017-02-15 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-8-77
更新日期：2008-06-06 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
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更新日期：2019-04-25 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章,评审
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更新日期：2018-07-11 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4229-3
更新日期：2019-07-05 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4696-6
更新日期：2019-12-19 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-017-2456-z
更新日期：2017-05-16 00:00:00
abstract：BACKGROUND:While several studies have assessed the associations between biological factors and tuberculosis (TB) transmission, our understanding of the associations between TB transmission and social and economic factors remains incomplete. We aimed to explore associations between community TB transmission and socio-ec...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-020-4828-z
更新日期：2020-02-10 00:00:00
abstract：BACKGROUND:Adjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce. Here, we investigated BKPyV-specific T cell immunity in KT recipients diagnosed with BKPyVAN. METHO...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-019-4615-x
更新日期：2019-11-19 00:00:00
