Abstract:
BACKGROUND:Procalcitonin (PCT) has become a commonly used serum inflammatory marker. Our aim was to describe the kinetics and usefulness of serial post-operative PCT measurements to detect bacterial infection in a cohort of children immediately after pediatric liver transplantation (pLT). METHODS:We performed a retrospective chart review of a cohort of pLT recipients with serial serum PCT measurements in the first week following pLT. The presence of infection was determined on clinical and biological parameters. Normal PCT was defined as < 0.5 (ng/ml). RESULTS:Thirty-nine patients underwent 41 pLT. PCT was measured daily during the first week post pLT. Values first increased following surgery and then decreased, nearing 0.5 ng/ml at day seven. Peak PCT reached a median of 5.61 ng/ml (IQR 3.83-10.8). Seventeen patients were considered to have an infection. There was no significant difference in daily PCT or peak PCT between infected and non infected patients during the first post-operative week. AUC of ROC curve for PCT during first week was never higher than 0.6. CONCLUSIONS:We conclude that serial PCT measurements during the first week after pLT is not useful to identify patients with bacterial infections. Rather, we propose that serum PCT may be useful after the first week post pLT.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Cousin VL,Lambert K,Trabelsi S,Galetto-Lacour A,Posfay-Barbe KM,Wildhaber BE,McLin VAdoi
10.1186/s12879-017-2234-ysubject
Has Abstractpub_date
2017-02-15 00:00:00pages
149issue
1issn
1471-2334pii
10.1186/s12879-017-2234-yjournal_volume
17pub_type
杂志文章abstract:BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) represent an important global threat. The aim of this study is to describe the clinical course and outcomes of patients with CRE infections treated with ceftazidime-avibactam (CAZ-AVI) compared to patients treated with other agents. METHODS:A retrospective cohor...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4409-1
更新日期:2019-09-04 00:00:00
abstract:BACKGROUND:Microascus cirrosus, the teleomorph of Scopulariopsis spp., is a saprobic species with a worldwide distribution and rarely causes human infection. In the present paper, we present the first case of primary cutaneous M. cirrosus infection in a Chinese female. CASE PRESENTATION:A 17-year-old female presented ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3535-5
更新日期:2018-12-03 00:00:00
abstract:BACKGROUND:The ocular manifestations of HIV may lead to visual impairment or blindness. In India, patients typically initiate antiretroviral treatment (ART) with low CD4 cell counts when the risk of ocular complications may be high. The objective of this study was to determine the prevalence and types of HIV-associated...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-158
更新日期:2009-09-23 00:00:00
abstract:BACKGROUND:The risk of life-threatening complications, such as visceral disseminated varicella zoster virus (VZV) infection, is greater in immunosuppressed individuals, such as systemic lupus erythematosus (SLE) patients. CASE PRESENTATION:Here, a case is reported of a Caucasian woman diagnosed with lupus nephritis an...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05254-6
更新日期:2020-07-23 00:00:00
abstract:BACKGROUND:Screening for benign or malignant process of pelvis in young females is a challenge for a physician in a limited resource country. Tuberculosis should be always considered in the differential diagnosis of a pelvic mass in countries with high prevalence of tuberculosis. Negative results of analysis of periton...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-017-2237-8
更新日期:2017-02-07 00:00:00
abstract:BACKGROUND:In the pre-vaccine era, invasive disease with Haemophilus influenzae, type b (Hib) commonly presented with osteoarticular involvement. Haemophilus influenzae, type a (Hia) sepsis is a rare but emerging problem in recent years. Here, we report a case of sepsis with concomitant osteoarthritis due to Hia that w...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4572-4
更新日期:2019-11-08 00:00:00
abstract:BACKGROUND:Asplenic individuals are susceptible for overwhelming infection with Streptococcus pneumoniae, carrying a high mortality. Although Toll-like receptor (TLR)-2 is considered the major receptor for Gram-positive bacteria in innate immunity, it does not play a major role in host defense against pneumococcal pneu...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-12-139
更新日期:2012-06-21 00:00:00
abstract:BACKGROUND:To probe seroepidemiology of the 2009 pandemic influenza A (H1N1) among health care workers (HCWs) in a children's hospital. METHODS:From August 2009 to March 2010, serum samples were drawn from 150 HCWs in a children's hospital in Taipei before the 2009 influenza A (H1N1) pandemic, before H1N1 vaccination,...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-12-89
更新日期:2012-04-13 00:00:00
abstract:BACKGROUND:The spread of multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M. tuberculosis) strains has been a big challenge to the TB control and prevention in China. Knowledge about patterns of drug resistance in TB high-burden areas of China is crucial to develop appropriate control strategies. W...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1848-9
更新日期:2016-09-27 00:00:00
abstract:BACKGROUND:The most optimal antifungal agent for empiric treatment of invasive fungal diseases (IFDs) in febrile neutropenia is controversial. Our objective was evaluate the relative efficacy of antifungals for all-cause mortality, fungal infection-related mortality and treatment response in this population. METHODS:P...
journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12879-017-2263-6
更新日期:2017-02-20 00:00:00
abstract:BACKGROUND:Pneumonia has traditionally been classified into two subtypes: community-acquired pneumonia (CAP) and nosocomial pneumonia (NP). Recently, a new entity has been defined, called healthcare-associated pneumonia (HCAP). Few studies have investigated the potential of population-based, electronic, healthcare data...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-559
更新日期:2013-11-25 00:00:00
abstract:BACKGROUND:Undernutrition is one of the most common problems among people living with HIV, contributing to premature death and the development of comorbidities within this population. In Sub-Saharan Africa (SSA), the impacts of these often inter-related conditions appear in a series of fragmented and inconclusive studi...
journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析
doi:10.1186/s12879-020-05706-z
更新日期:2021-01-04 00:00:00
abstract:BACKGROUND:Haemophilus influenzae type b (Hib) vaccination led to a significant decrease in invasive bacterial infections in children. The aim of this study was to assess a potential shift to more non-type b invasive infections in a population with high Hib vaccination coverage and to compare the burden of suffering be...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-45
更新日期:2009-04-20 00:00:00
abstract:BACKGROUND:Arthropod-borne viral encephalitis of diverse origins shows similar clinical symptoms, histopathology and magnetic resonance imaging, indicating that the patho mechanisms may be similar. There is no specific therapy to date. However, vaccination remains the best prophylaxis against a selected few. Regardless...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-306
更新日期:2013-07-03 00:00:00
abstract:BACKGROUND:Cutaneous leishmaniasis (CL) is an important public health problem in Brazil and in several tropical regions of the world. In the Americas, Brazil is the country with the highest number of registered cases. In Brazil, the state of Minas Gerais has the highest number of cases in the southeastern region. In th...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3940-4
更新日期:2019-04-11 00:00:00
abstract:BACKGROUND:Acute myopericarditis and exertional rhabdomyolysis, two uncommon but well-described diseases with potentially life-threatening effects, are generally considered as independent clinical entities. However, they may in fact be pathophysiologically related under certain circumstances. This is the first ever rep...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-283
更新日期:2013-06-21 00:00:00
abstract:BACKGROUND:Implant-related infections, including those of peri-prosthetic joint (PJIs), osteosynthesis and other biomaterials, are biofilm-related. Pathogen identification is considered the diagnostic benchmark; however, the presence of bacterial biofilms makes pathogen detection with traditional microbiological techni...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3050-8
更新日期:2018-04-02 00:00:00
abstract:BACKGROUND:Long-term outcome of DAAs therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort of HCV-infected kidney transplant recipients. METHODS:Single-center and retrospective study of HCV-infected kidney transplant recipients initiating an DAAs regimen between January...
journal_title:BMC infectious diseases
pub_type: 临床试验,杂志文章
doi:10.1186/s12879-019-4217-7
更新日期:2019-07-19 00:00:00
abstract:BACKGROUND:People successfully completing treatment for tuberculosis remain at elevated risk for recurrent disease, either from relapse or reinfection. Identifying risk factors for recurrent tuberculosis may help target post-tuberculosis screening and care. METHODS:We enrolled 500 patients with smear-positive pulmonar...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05515-4
更新日期:2020-10-23 00:00:00
abstract:BACKGROUND:Brucella abortus is a highly pathogenic zoonotic agent, tempting for the development of a rapid diagnostic method to enable adequate treatment and prevent further spread. Enrichment of the bacteria is often used as a first step in diagnostics to increase the bacterial number above the detection limit of the ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3134-5
更新日期:2018-06-05 00:00:00
abstract:INTRODUCTION:The World Health Organization recommends that countries conduct two phase evaluations of HIV rapid tests (RTs) in order to come up with the best algorithms. In this report, we present the first ever such evaluation in Uganda, involving both blood and oral based RTs. The role of weak positive (WP) bands on ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3001-4
更新日期:2018-02-27 00:00:00
abstract:BACKGROUND:Risk of pneumocystosis after discontinuation of primary or secondary prophylaxis among HIV-infected patients before CD4 counts increase to >==200 cells/microL (early discontinuation) after receiving highly active antiretroviral therapy (HAART) is rarely investigated. METHODS:Medical records of 660 HIV-infec...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-126
更新日期:2010-05-21 00:00:00
abstract:BACKGROUND:It is estimated that Lao People's Democratic Republic (Lao PDR) ranks fifth among the seven countries most affected by TB in the WHO Western Pacific Region. However, because of late implementation of mycobacterial culture, no study on resistance to anti-TB drugs had been performed yet. The objective of this ...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2334-13-275
更新日期:2013-06-19 00:00:00
abstract:BACKGROUND:Enterovirus 71 (EV-A71) shows a potential of rapid death, but the natural history of the infection is poorly known. This study aimed to examine the natural history of EV-A71 infection. METHODS:This was a prospective longitudinal observational study performed between January 1st and October 31st, 2012, at th...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/s12879-017-2228-9
更新日期:2017-02-17 00:00:00
abstract:BACKGROUND:Drug resistant organisms pose an increasing threat to the successful treatment of common infections. Understanding colonization patterns of these bacteria is important for effective antibiotic treatment and infection control guidelines. METHODS:A prospective observational study was performed to determine th...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-14-298
更新日期:2014-06-02 00:00:00
abstract:BACKGROUND:A more stringent QuantiFERON-TB Gold In-Tube (QFT) conversion (from negative to positive) definition has been proposed to allow more definite detection of recent tuberculosis (TB) infection. We explored alternative conversion definitions to assist the interpretation of serial QFT results and estimate inciden...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12879-020-05483-9
更新日期:2020-10-15 00:00:00
abstract:BACKGROUND:Drug susceptibility testing (DST) remains an important concern for implementing treatment of MDR tuberculosis patients. Implementation of molecular tests for drug resistance identification would facilitate DST particularly in developing countries where culturing is difficult to perform. We have characterized...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-11-255
更新日期:2011-09-28 00:00:00
abstract:BACKGROUND:Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION:We report the first case of CHIKV infec...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-200
更新日期:2009-12-10 00:00:00
abstract:BACKGROUND:Febrile jaundice results clinically in generalized yellow coloration of the teguments and mucous membranes due to excess plasma bilirubin, accompanied by fever. Two types are found: conjugated and unconjugated bilirubin jaundice. Jaundice is a sign in several diseases due to viruses (viral hepatitis and arbo...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-017-2840-8
更新日期:2017-11-29 00:00:00
abstract:BACKGROUND:Data on sexually transmitted infections (STIs) in Saudi Arabia (SA) and other Islamic countries are limited. This study describes the results of a five-year surveillance for STIs in SA. METHODS:This is a case series descriptive study of all confirmed STIs diagnosed in SA from January, 1995 through December,...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-6-3
更新日期:2006-01-10 00:00:00