Cholecystokinin receptor-1 mediates the inhibitory effects of exogenous cholecystokinin octapeptide on cellular morphine dependence.

abstract：BACKGROUND:As development proceeds the human embryo attains an ever more complex three dimensional (3D) structure. Analyzing the gene expression patterns that underlie these changes and interpreting their significance depends on identifying the anatomical structures to which they map and following these patterns in dev...

journal_title：BMC neuroscience

authors： Kerwin J,Scott M,Sharpe J,Puelles L,Robson SC,Martínez-de-la-Torre M,Ferran JL,Feng G,Baldock R,Strachan T,Davidson D,Lindsay S

更新日期：2004-08-06 00:00:00

abstract：BACKGROUND:Functional magnetic resonance imaging (fMRI) in white matter has long been considered controversial. Recently, this viewpoint has been challenged by an emerging body of evidence demonstrating white matter activation in the corpus callosum. The current study aimed to determine whether white matter activation ...

journal_title：BMC neuroscience

authors： Gawryluk JR,Mazerolle EL,Brewer KD,Beyea SD,D'Arcy RC

更新日期：2011-06-14 00:00:00

abstract：BACKGROUND:Histone deacetylases (HDACs) are enzymes that modulate gene expression and cellular processes by deacetylating histones and non-histone proteins. While small molecule inhibitors of HDAC activity (HDACi) are used clinically in the treatment of cancer, pre-clinical treatment models suggest they also exert neur...

journal_title：BMC neuroscience

authors： Zhou Q,Dalgard CL,Wynder C,Doughty ML

更新日期：2011-05-26 00:00:00

abstract：BACKGROUND:Human brain microvascular endothelial cells (hBMVECs) are integral part of the blood brain barrier. Post-translational modifications of adherens junction proteins regulate the permeability of human brain microvascular endothelial cells. Pro-inflammatory signals can induce tyrosine phosphorylation of adherens...

journal_title：BMC neuroscience

authors： Mishra R,Singh SK

更新日期：2014-06-26 00:00:00

abstract：BACKGROUND:Traumatic brain injury (TBI) initiates a complex sequence of destructive and neuroprotective cellular responses. The initial mechanical injury is followed by an extended time period of secondary brain damage. Due to the complicated pathological picture a better understanding of the molecular events occurring...

journal_title：BMC neuroscience

authors： von Gertten C,Flores Morales A,Holmin S,Mathiesen T,Nordqvist AC

更新日期：2005-11-30 00:00:00

abstract：BACKGROUND:In rodents, dietary Na+ deprivation reduces gustatory responses of primary taste fibers and central taste neurons to lingual Na+ stimulation. However, in the rat taste bud cells Na+ deprivation increases the number of amiloride sensitive epithelial Na+ channels (ENaC), which are considered as the "receptor" ...

journal_title：BMC neuroscience

authors： Huang T,Stähler F

更新日期：2009-03-12 00:00:00

abstract：BACKGROUND:This study examined the relationship of the arithmetic mismatch negativity (AMN) and the semantic evaluation of numerical magnitude. The first question was whether the AMN was sensitive to the incongruity in numerical information per se, or rather, to the violation of strategic expectations. The second quest...

journal_title：BMC neuroscience

authors： Hsu YF,Szücs D

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:Low-intensity pulsed ultrasound stimulation (LIPUS) has been proven to be a noninvasive method with high spatial resolution and deep penetration. Previous studies have qualitatively demonstrated that the electromyographic response caused by LIPUS in the mouse motor cortex is affected by the anesthetic state ...

journal_title：BMC neuroscience

authors： Yuan Y,Wang X,Yan J,Li X

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:Alzheimer's Disease (AD) is the most common of the conformational neurodegenerative disorders characterized by the conversion of a normal biological protein into a β-sheet-rich pathological isoform. In AD the normal soluble Aβ (sAβ) forms oligomers and fibrils which assemble into neuritic plaques. The most t...

journal_title：BMC neuroscience

authors： Chung E,Ji Y,Sun Y,Kascsak RJ,Kascsak RB,Mehta PD,Strittmatter SM,Wisniewski T

更新日期：2010-10-14 00:00:00

abstract：BACKGROUND:The integration of EEG and fMRI is attractive because of their complementary precision regarding time and space. But the relationship between the indirect hemodynamic fMRI signal and the more direct EEG signal is uncertain. Event-related EEG responses can be analyzed in two different ways, reflecting two dif...

journal_title：BMC neuroscience

authors： Foucher JR,Otzenberger H,Gounot D

更新日期：2003-09-19 00:00:00

abstract：BACKGROUND:Bone morphogenic proteins (BMPs) promote the survival of neurons, suggesting a therapeutic application of BMPs in the treatment of acute and chronic neurodegenerative disorders. However, the application of recombinant BMPs in vivo is limited by their short half-life. To provide a continuous supply for functi...

journal_title：BMC neuroscience

authors： Heinonen AM,Rahman M,Dogbevia G,Jakobi H,Wölfl S,Sprengel R,Schwaninger M

更新日期：2014-03-11 00:00:00

abstract：BACKGROUND:Adult neurogenesis continuously adds new neurons to the dentate gyrus and the olfactory bulb. It involves the proliferation and subsequent differentiation of neuronal progenitors, and is thus closely linked to the cell cycle machinery. Cell cycle progression is governed by the successive expression, activati...

journal_title：BMC neuroscience

authors： Ansorg A,Witte OW,Urbach A

更新日期：2012-05-07 00:00:00

abstract：BACKGROUND:This work examines the central nervous system distribution of virus-labeled neurons from the rat urinary bladder and the prostate simultaneously within the same tissue sections. Two immunohistochemically distinct pseudorabies virus strains were simultaneously injected into male Sprague Dawley rats (approxima...

journal_title：BMC neuroscience

authors： Nadelhaft I,Miranda-Sousa AJ,Vera PL

更新日期：2002-07-12 00:00:00

abstract：BACKGROUND:To reach and grasp an object in space on the basis of its image cast on the retina requires different coordinate transformations that take into account gaze and limb positioning. Eye position in the orbit influences the image's conversion from retinotopic (eye-centered) coordinates to an egocentric frame nec...

journal_title：BMC neuroscience

authors： Andersson F,Etard O,Denise P,Petit L

更新日期：2004-09-19 00:00:00

abstract：BACKGROUND:Granulocyte-macrophage colony stimulating factor (GM-CSF) is a hematopoietic growth factor involved in the generation of granulocytes, macrophages, and dendritic cells from hematopoietic progenitor cells. We have recently demonstrated that GM-CSF has anti-apoptotic functions on neurons, and is neuroprotectiv...

journal_title：BMC neuroscience

authors： Krüger C,Laage R,Pitzer C,Schäbitz WR,Schneider A

更新日期：2007-10-22 00:00:00

abstract：BACKGROUND:The effects induced by administering the anticonvulsant lamotrigine, the preferential inhibitor of neuronal nitric oxide synthase 7-nitroindazole and the precursor of NO synthesis L-arginine, alone or in combination, on an experimental model of partial complex seizures (maximal dentate gyrus activation) were...

journal_title：BMC neuroscience

authors： Sardo P,Ferraro G

更新日期：2007-07-03 00:00:00

abstract：BACKGROUND:Recovery following stroke depends on cellular plasticity in the perilesional zone (PZ). Doublecortin (DCX), a protein mainly labeling immature neurons in neurogenic niches is also highly expressed in the vicinity of focal cortical infarcts. Notably, the number of DCX+ cells positively correlates with the rec...

journal_title：BMC neuroscience

authors： Kunze A,Achilles A,Keiner S,Witte OW,Redecker C

更新日期：2015-04-15 00:00:00

abstract：BACKGROUND:Evoked potentials have been proposed to result from phase-locking of electroencephalographic (EEG) activities within specific frequency bands. However, the respective contribution of phasic activity and phase resetting of ongoing EEG oscillation remains largely debated. We here applied the EEGlab procedure i...

journal_title：BMC neuroscience

authors： Cheron G,Cebolla AM,De Saedeleer C,Bengoetxea A,Leurs F,Leroy A,Dan B

更新日期：2007-09-18 00:00:00

abstract：BACKGROUND:Glutamate, a major excitatory amino acid neurotransmitter, causes apoptotic neuronal cell death at high concentrations. Our previous studies have shown that depending on the neuronal cell type, glutamate-induced apoptotic cell death was associated with regulation of genes such as Bcl-2, Bax, and/or caspase-3...

journal_title：BMC neuroscience

authors： Zhang Y,Bhavnani BR

更新日期：2006-06-15 00:00:00

abstract：BACKGROUND:Lateralized processing of speech is a well studied phenomenon in humans. Both anatomical and neurophysiological studies support the view that nonhuman primates and other animal species also reveal hemispheric differences in areas involved in sound processing. In recent years, an increasing number of studies ...

journal_title：BMC neuroscience

authors： Fischer J,Teufel C,Drolet M,Patzelt A,Rübsamen R,von Cramon DY,Schubotz RI

更新日期：2009-02-24 00:00:00

abstract：BACKGROUND:Numerous electrophysiological, ultrastructural, and immunocytochemical studies on rodent taste buds have been carried out on rat taste buds. In recent years, however, the mouse has become the species of choice for molecular and other studies on sensory transduction in taste buds. Do rat and mouse taste buds ...

journal_title：BMC neuroscience

authors： Ma H,Yang R,Thomas SM,Kinnamon JC

更新日期：2007-01-05 00:00:00

abstract：BACKGROUND:Recent alleged attacks with nerve agent sarin on civilians in Syria indicate their potential threat to both civilian and military population. Acute nerve agent exposure can cause rapid death or leads to multiple and long term neurological effects. The biochemical changes that occur following nerve agent expo...

journal_title：BMC neuroscience

authors： RamaRao G,Afley P,Acharya J,Bhattacharya BK

更新日期：2014-04-04 00:00:00

abstract：BACKGROUND:An individual's ability to recognise and pay attention to others is crucial in order to behave appropriately in various social situations. Studies in humans have shown a sex bias in sociability as well as social memory, indicating that females have better face memory and gaze more at the eyes of others, but ...

journal_title：BMC neuroscience

authors： Karlsson SA,Haziri K,Hansson E,Kettunen P,Westberg L

更新日期：2015-11-25 00:00:00

abstract：BACKGROUND:A recent study of lateral septum (LS) suggested a large number of autism-related genes with altered expression in the postpartum state. However, formally testing the findings for enrichment of autism-associated genes proved to be problematic with existing software. Many gene-disease association databases hav...

journal_title：BMC neuroscience

authors： Eisinger BE,Saul MC,Driessen TM,Gammie SC

更新日期：2013-11-19 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is the most prevalent form of dementia and represents one of the highest unmet requirements in medicine today. There is shortage of novel molecules entering into market because of poor pharmacokinetic properties and safety issues. Drug repurposing offers an opportunity to reinvigorat...

journal_title：BMC neuroscience

authors： Kumar S,Chowdhury S,Kumar S

更新日期：2017-10-27 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the distribution of key SNARE proteins in glutamatergic and GABAergic synapses of the adult rat cerebellar cortex using light microscopy immunohistochemical techniques. Analysis was made of co-localizations of vGluT-1 and vGluT-2, vesicular transporters of glutamate and ma...

journal_title：BMC neuroscience

authors： Benagiano V,Lorusso L,Flace P,Girolamo F,Rizzi A,Bosco L,Cagiano R,Nico B,Ribatti D,Ambrosi G

更新日期：2011-11-17 00:00:00

abstract：BACKGROUND:Hyperbaric oxygen therapy (HBOT) is a known adjuvant for treating ischemia-related inner ear diseases. Controversies still exist in the role of HBOT in cochlear diseases. Few studies to date have investigated the cellular changes that occur in inner ears after HBOT. Nitric oxide, which is synthesized by nitr...

journal_title：BMC neuroscience

authors： Lin CD,Wei IH,Lai CH,Hsia TC,Kao MC,Tsai MH,Wu CH,Tsai MH

更新日期：2011-02-22 00:00:00

abstract：BACKGROUND:Magnetoencephalography (MEG) has become an increasingly popular technique for non-invasively characterizing neuromagnetic field changes in the brain at a high temporal resolution. To examine the reliability of the MEG signal, we compared magnetic and electrophysiological responses to complex natural stimuli ...

journal_title：BMC neuroscience

authors： Zhu Z,Zumer JM,Lowenthal ME,Padberg J,Recanzone GH,Krubitzer LA,Nagarajan SS,Disbrow EA

更新日期：2009-01-15 00:00:00

abstract：BACKGROUND:Ample evidence suggests a substantial contribution of cellular and molecular changes in the spinal cord to the induction and persistence of chronic neuropathic pain conditions. While for a long time, proteases were mainly considered as protein degrading enzymes, they are now receiving growing interest as sig...

journal_title：BMC neuroscience

authors： Leichsenring A,Bäcker I,Wendt W,Andriske M,Schmitz B,Stichel CC,Lübbert H

更新日期：2008-08-12 00:00:00

abstract：BACKGROUND:Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities of daily living (ADL). It is not known if relatively s...

journal_title：BMC neuroscience

authors： Hummel FC,Voller B,Celnik P,Floel A,Giraux P,Gerloff C,Cohen LG

更新日期：2006-11-03 00:00:00