当前位置： SCI文献检索 > Health and Quality of Life Outcomes期刊下所有文献 > Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study.

Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study.

Abstract：

BACKGROUND:Restless legs syndrome (RLS) is a chronic disorder with substantial impact on quality of life similar to that seen in diabetes mellitus or osteoarthritis. Little is known about the psychological characteristics of RLS patients although psychological factors may contribute to unfavourable treatment outcome. METHODS:In an observational cross-sectional design, we evaluated the psychological features of 166 consecutive RLS patients from three outpatient clinics, by means of the Symptom Checklist 90-R (SCL-90-R) questionnaire. Additionally, the Beck Depression Inventory-II (BDI-II) and the International RLS Severity Scale (IRLS) were measured. Both treated and untreated patients were included, all patients sought treatment. RESULTS:Untreated patients (n = 69) had elevated but normal scores on the SCL-90-R Global Severity Index (GSI; p = 0.002) and on the sub-scales somatisation (p < 0.001), compulsivity (p = 0.003), depression (p = 0.02), and anxiety (p = 0.004) compared with a German representative sample. In the treated group, particularly in those patients who were dissatisfied with their actual treatment (n = 62), psychological distress was higher than in the untreated group with elevated scores for the GSI (p = 0.03) and the sub-scales compulsivity (p = 0.006), depression (p = 0.012), anxiety (p = 0.031), hostility (p = 0.013), phobic anxiety (p = 0.024), and paranoid ideation (p = 0.012). Augmentation, the most serious side effect of dopaminergic, i.e. first-line treatment of RLS, and loss of efficacy were accompanied with the highest psychological distress, as seen particularly in the normative values of the sub-scales compulsivity and anxiety. Generally, higher RLS severity was correlated with higher psychological impairment (p < 0.001). CONCLUSION:Severely affected RLS patients show psychological impairment in multiple psychological domains which has to be taken into account in the treatment regimen.

journal_name

Health Qual Life Outcomes

journal_title

Health and quality of life outcomes

authors

Scholz H,Benes H,Happe S,Bengel J,Kohnen R,Hornyak M

doi

10.1186/1477-7525-9-73

subject

Has Abstract

pub_date

2011-09-20 00:00:00

pages

issn

1477-7525

pii

1477-7525-9-73

journal_volume

pub_type

杂志文章,多中心研究

在线工具

Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study.