Abstract：
BACKGROUND:Maternal serum anti-D is actively transported across the placenta into the fetal blood where it adheres to D-positive erythrocytes. The anti-D coated red cells attach to Fc-receptors on fetal reticuloendothelial cells and are subsequently phagocytosed and hemolysed. It is not known if anti-D is consumed or recirculated in this process. MAIN QUESTION: Is anti-D in the fetus consumed in the hemolytic process in the erythroblastotic fetus and can the consumption be modulated by high-dose immunoglobulins (i.v.IG) given to the mother? METHODS:Fetal/maternal serum anti-D concentration ratios were calculated for simultaneously taken blood samples from three groups of Rh(D) immunized pregnant women; six women with fetuses who were of Rh(D) negative phenotype, 19 women with fetuses who were Rh(D) positive and received no treatment and, seven women who were treated with i.v.IG because they bore anemic, Rh(D) positive fetuses. RESULTS:Fetuses with a Rh(D) negative phenotype expressed an increase in fetal/maternal anti-D concentration ratios from 10 to 55% between 25 and 31 gestational weeks, while Rh(D) positive fetuses without i.v.IG treatment had stable values at the 10% level between 24 and 35 gestational weeks. During i.v.IG-treatment of the mothers, Rh(D) positive fetuses showed an increase in ratio from 10 to 30% between 26 and 34 gestational weeks. There was a statistically significant (p<0.001) difference between regression results of the three groups. CONCLUSIONS:Fetal anti-D is consumed in the hemolytic process and the consumption can be modulated by i.v.IG given to the mother.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Gottvall T,Selbing Asubject
Has Abstractpub_date
1998-05-01 00:00:00pages
500-3issue
5eissn
0001-6349issn
1600-0412journal_volume
77pub_type
杂志文章abstract：BACKGROUND:GnRH agonists constitute a well-documented treatment for premenstrual syndrome (PMS). However, the hypo-estrogenic state induced by the treatment renders it less suitable for long-term clinical use. The aim of the current study was to investigate the efficacy of a low dose GnRH agonist with respect to its ab...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:As the patterns and frequency of maternal and clinical conditions and outcomes and gross and histological placental features and lesions vary with gestational age at delivery, we aimed to study the impact of these changes on the placental diagnosis, hoping to uncover potential novel clusters of gestational ag...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12350
更新日期：2014-04-01 00:00:00
abstract：:Zinc and alkaline phosphatase were examined in 41 pregnant women (gestational weeks 35-41) and in 12 women within 24 h of delivery. The serum-zinc level was reduced in all the women, though to a lesser degree in women giving birth to small for gestational age (SGA) babies than in the control mothers. The difference be...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348709022042
更新日期：1987-01-01 00:00:00
abstract：:Three cases with metastasized choriocarcinoma are reported. The basic chemotherapeutic regimen was methotrexate and actinomycin D, combined with cyclophosphamide or vinblastine. Surgery was used in the treatment of both primary and metastatic lesions. The chief indications for hysterectomy arise when chemotherapy has ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348409155520
更新日期：1984-01-01 00:00:00
abstract：OBJECTIVE:To assess the extent to which the Enzian classification correlates with the revised American Society for Reproductive Medicine (rASRM) score and clinical symptoms in women with deeply infiltrating endometriosis. DESIGN:Retrospective cohort study (Canadian Task Force classification II-2). SETTING:Endometrios...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12118
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:To determine the risk of endometrial cancer when endometrial thickness is not visualized using ultrasonography. DESIGN:Cross-sectional study. SETTING:Gynecological oncology center in the United Kingdom. POPULATION:All postmenopausal women referred with vaginal bleeding. METHODS:All women were investigated...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2012.01407.x
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Ectopic pregnancy is still a major health problem among women of childbearing age in our community. The majority of the patients with ectopic pregnancy are nulliparous in their mid twenties, with previous induced abortion(s) and or pelvic inflammatory disease. It remains a major challenge to the reproductive...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0412.2002.811207.x
更新日期：2002-12-01 00:00:00
abstract：BACKGROUND:To study factors influencing delivery method in breech presentation. METHODS:Population based cohort study from The Medical Birth Registry of Norway, comprising all singleton deliveries in Norway, 1967-1994, 1,592,064 deliveries of which 45,921 (2.9%) were in breech presentation. RESULTS:The proportion of ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:During the last years, the incidence of obstetric anal sphincter rupture (OASR) has increased markedly in Sweden, and significantly less frequently in Italy. Our objective was to explore if different delivery management may explain the variation in OASR incidences. METHODS:In a retrospective study, data fro...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章,多中心研究
doi：10.1080/00016340701832661
更新日期：2008-01-01 00:00:00
abstract：:The anatomy of the thrombus in acute deep vein thrombosis (DVT) in women using oral contraceptives was studied in 277 reports on DVT received by the Swedish Adverse Drug Reaction Advisory Committee (SADRAC). The study revealed a similarity between the anatomy of DVT in women on oral contraceptives and that of DVT in p...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348509155155
更新日期：1985-01-01 00:00:00
abstract：OBJECTIVE:To revise, validate and test for reliability an anal sphincter rupture questionnaire in relation to construct, content and face validity. SETTING AND BACKGROUND: Since 1996 women with anal sphincter rupture (ASR) at one of the public university hospitals in Copenhagen, Denmark have been offered pelvic floor m...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1080/00016340802443814
更新日期：2009-01-01 00:00:00
abstract：:Minor degrees of endometriosis have often been regarded as being of no import and hence remain untreated, but a study of the natural history of endometriosis has demonstrated that 47% (95% confidence limits, 23-71%) of patients (n=35) given placebo in a double-blind, randomized controlled trial showed progression of t...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.1989.68.s150.27
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:To investigate the role of interleukin-1 related substances in amniotic fluid in normal term labor without intrauterine infection. METHODS:Amniotic fluid samples were collected from forty-one patients with various backgrounds. A novel pre-assay treatment using Frigen II was introduced to improve the recover...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:In 136 patients, who underwent induced abortion by the vacuum curettage method under local anaesthesia (paracervical block), the effect of 10 mg diazepam intravenously as preoperative sedative was investigated for its ability to abolish the subjective experience of pain. The trial was carried out as a paired sample, r...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.3109/00016347509157768
更新日期：1975-01-01 00:00:00
abstract：:Persistently elevated levels of serum human chorionic gonadotropin (hCG) in women call for a tumor investigation, if pregnancy can be ruled out. We present a case of increased hCG concentrations for 1 1/2 years. Radiolabelled antibody directed against the hCG molecule indicated the source of production to be a chorioc...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348909020999
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Excellent metabolic control before conception and during diabetic pregnancies is the aim in order to avoid malformations and perinatal morbidity. Since an inverse correlation between median blood glucose concentration (BG) and hypoglycemia as well as a high prevalence of nocturnal hypoglycemia have been desc...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:To understand the mechanism of biological action of gestrinone (R2323), which has a therapeutic effect against endometriosis, the binding of gestrinone to numerous classes of intracellular steroid binding proteins was studied in the human uterine endometrium. Gestrinone bound to endometrial receptors for estrogen, pro...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016348609157380
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND:Patients after treatment for cervical cancer have increased risk of developing second squamous cell malignancy of the lower genital tract. MATERIAL AND METHODS:A retrospective study of 46 patients with second lower genital tract epidermoid cancers following previous treatment for invasive cervical carcinoma...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:The cause of transient stress urinary incontinence during pregnancy remains uncertain. Anatomical change, such as a pressure effect of the enlarged uterus, changes in renal function, and alterations in bladder and urethral function have been proposed. There is little information about the role of reproductiv...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1034/j.1600-0412.2001.801209.x
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Pregnancy and puerperium are associated with an increased risk of venous thromboembolism. Low-molecular-weight heparin is the anticoagulant of choice in pregnant women because, unlike warfarin, it does not cross the placenta. However, there are limited data on the risk of adverse birth outcomes following use...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:Elevated serum lipids in normal pregnancy have been confirmed by the present study. In normal pregnancy the relative fatty acid composition of serum lecithin was characteristically high in palmitic acid (15:0). From the present knowledge of lipid metabolism in pregnancy there is no obvious explanation for this finding...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347509157774
更新日期：1975-01-01 00:00:00
abstract：INTRODUCTION:Emergency contraception must be followed by the use of an effective method of contraception in order to reduce future risk of unintended pregnancies. Provision of long-acting reversible contraception (LARC) is highly effective in this regard. The aim of our study was to compare use of an effective method o...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.12916
更新日期：2016-08-01 00:00:00
abstract：INTRODUCTION:Our aim was to investigate the rate of vascular dementia and dementia in women with previous hypertensive disorders in pregnancy, since white matter lesions of the brain and cardiovascular disease are linked both to dementia and hypertensive disorders in pregnancy. MATERIAL AND METHODS:Prospective populat...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/aogs.13096
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To study the association between maternal weight gain in pregnancy and fetal abdominal circumference in the second trimester. DESIGN:Prospective cross-sectional study. SETTING:Low-risk antenatal clinic. POPULATION:Six hundred and fifty women with low-risk pregnancy. METHODS:Women with a regular menstrual ...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.1111/j.1600-0412.2011.01129.x
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of three different doses of Nestorone progestin administered by implants for relief of pain, as well as bleeding patterns and symptoms in women with endometriosis. DESIGN:An open clinical study without a control group. PATIENTS:Twenty-one women in whom endometriosis was diagnosed an...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-02-01 00:00:00
abstract：:In this paper we present a patient with an initially questionable history of neonatal alloimmune thrombocytopenia (NAT) due to materno-fetal HPA-1a (PLA1) incompatibility. No circulating antibodies were detectable in untreated maternal serum, but an adsorption/elution technique enabled the demonstration of the platele...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349309058169
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVES:to evaluate the additional information of second trimester magnetic resonance imaging (MRI) compared to ultrasound in fetuses with identified or suspected central nervous system (CNS) anomalies and to study the clinical impact of the information on pregnancy management. DESIGN:prospective study during 2004-...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349.2010.526184
更新日期：2010-12-01 00:00:00
abstract：:Ovarian cancer often presents at an advanced stage, but tends to be an intra-peritoneal disease that respects peritoneal planes. Thus, colo-rectal perforation of the tumor is an extremely rare presentation. The surgical treatment of malignant colo-ovarian fistula should include complete cyto-reduction at the same time...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016349.2010.501857
更新日期：2010-10-01 00:00:00
abstract：:Dehydroepiandrosterone sulfate (DHAS) is now used for a dynamic test of placental function by many obstetricians. While practicing this test, the authors found that DHAS markedly promoted so-called "cervical ripening". To study this problem, DHAS of 50 or 100 mg in multiple doses were injected into 132 Japanese pregna...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：10.3109/00016347809156518
更新日期：1978-01-01 00:00:00
abstract：BACKGROUND:To investigate Swedish county council members knowledge of the laws regulating infertility treatment, their understanding of the suggestions put forward in the report 'Priorities in Health Care' and their attitudes towards infertility. METHODS:All members (n=182) of the 1998 county councils of Linköping and...
journal_title：Acta obstetricia et gynecologica Scandinavica
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
