Abstract:
BACKGROUND:Pregnancy and puerperium are associated with an increased risk of venous thromboembolism. Low-molecular-weight heparin is the anticoagulant of choice in pregnant women because, unlike warfarin, it does not cross the placenta. However, there are limited data on the risk of adverse birth outcomes following use of low-molecular-weight heparin in pregnancy. PATIENTS AND METHODS:We performed a population-based cohort study to examine the safety of low-molecular-weight heparin use in pregnancy using data from the Pharmacoepidemiological Prescription Database, The Danish Medical Birth Registry and the Regional Hospital Discharge Registry in North Jutland County, Denmark. The birth outcomes in a cohort of 66 pregnant women treated with low-molecular-weight heparin between 1991-98 were compared with the birth outcomes of 17,259 pregnant women who did not receive any prescriptive drugs during pregnancy. RESULTS:No increased risk of malformations, low birth weight or stillbirth was found. However, an increased risk of pre-term delivery was found (odds ratio: 2.11, 95%, confidence interval: 0.96-4.65), which could reflect inherited thrombophilia as an indication of low-molecular-weight heparin. CONCLUSION:We have provided additional evidence of the safety of low-molecular-weight heparin use in pregnancy.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Sørensen HT,Johnsen SP,Larsen H,Pedersen L,Nielsen GL,Møller Msubject
Has Abstractpub_date
2000-08-01 00:00:00pages
655-9issue
8eissn
0001-6349issn
1600-0412journal_volume
79pub_type
杂志文章abstract::The use of gonadotropin-releasing hormone (GnRH) agonists in a long protocol appears to enhance the probability of conception in the presence of endometriosis. In addition, there is evidence to suggest that the use of prolonged downregulation with GnRH agonists prior to ovarian stimulation for in vitro fertilization (...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.0001-6349.2004.00543.x
更新日期:2004-07-01 00:00:00
abstract::The objective of this study was to assess the cost-effectiveness of hysterectomy performed for benign indications. Hysterectomy remains the most common major gynecological operation in the Western world. Rates of hysterectomy have not declined as expected with the introduction of new treatment options. Furthermore, us...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/aogs.12299
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:To study the effect of single-dose prophylactic Augmentin on patients undergoing cesarean section. METHODS AND MATERIAL:Three hundred and twenty women undergoing cesarean section were randomized into two groups in a prospective, double-blind, placebo-controlled study. One hundred and sixty women were alloca...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016349709024581
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:To assess the contribution of non-medical factors to actual mode of delivery in a setting with high cesarean rates. DESIGN:Follow-up survey. SETTING:University department of obstetrics and gynecology. SAMPLE:Women with singleton pregnancies (n = 453) where there was no awareness of medical contradictions t...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12466
更新日期:2014-10-01 00:00:00
abstract:INTRODUCTION:Some pregnant women develop significant proteinuria in the absence of hypertension. However, clinical significance of isolated gestational proteinuria (IGP) is not well understood. This study aimed to determine the prevalence of IGP in singleton pregnancies and the proportion of women with IGP who subseque...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,多中心研究
doi:10.1111/aogs.12915
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:At present, no proven recommendations can be made for the surveillance of tamoxifen-treated women. The aim of the present study was to evaluate ultrasonography and hysteroscopy in this setting. METHODS:Three hundred and ten postmenopausal patients using tamoxifen underwent vaginal ultrasonography, hysterosc...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0412.2002.811013.x
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To determine the contribution of maternal lipids in predicting large-for-gestational age (LGA) newborns born to women with gestational diabetes mellitus (GDM). DESIGN:Retrospective study. SETTING:Yonsei University Health System, Korea. POPULATION:A total of 104 women diagnosed with GDM between January 2000...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016341003605677
更新日期:2010-05-01 00:00:00
abstract::A fetal tibia was removed from the uterus of a woman who had had a legal abortion 8 years earlier, followed by tubal sterilization. Because of irregular vaginal bleeding she was hysterectomized and no sign of recanalization of the Fallopian tubes was seen peroperatively. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348609157363
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:In this cross-sectional study, we analyze whether foreign-born women in Sweden had more non-normal childbirths than Swedish-born women during 1996-1998, adjusting for age, parity, level of education, number of antenatal care visits, and complications in pregnancy. METHODS:The study includes 215 497 singleto...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00686.x
更新日期:2005-09-01 00:00:00
abstract::In a nationally representative sample (the Health 2000 Survey) comprising 3,937 Finnish women aged 30-99 years, we examined the association of miscarriage (assessed by questionnaire) with risk of cardiovascular disease (assessed by physician's examination and linkages to hospital discharge and drug reimbursement regis...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016340903380758
更新日期:2010-01-01 00:00:00
abstract::Forty infants delivered by vacuum extraction have been studied in the neonatal period--neurological examination, neonatal CSF-examinations, skull X-ray examination, transillumination and sonoencephalography --and at 14 months of age--developmental and behavioural evaluation, neurological examination, skull X-ray exami...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347709162119
更新日期:1977-01-01 00:00:00
abstract::Identification of poor fetal growth is an important objective of antenatal care. We evaluated the validity of the Wennergren score to predict small for gestational age and/or underweight for length infants (low ponderal index). To 405 randomly chosen pregnant women from our university hospital population, this numeric...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348909006141
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Adult granulosa cell tumor of the ovary is an uncommon neoplasm. The overall prognosis is favorable. The prognostic factors that are related to survival have not been well defined and are discussed in the literature amidst controversy. METHODS:Thirty-five patients diagnosed with adult granulosa cell tumor o...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340500324233
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:To investigate natural menstrual bleeding patterns in pre- and perimenopausal women, a prospective observational population study was carried out. METHODS:A total of 1616 (80.8%) of a population-based sample of 2000 Danish women aged 45-54 years answered an initial questionnaire. Of 1059 women with natural ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2004.00401.x
更新日期:2004-02-01 00:00:00
abstract::Diagnoses of complications in women who underwent pelvic floor surgery using meshes and the multidisciplinary management of these cases at two national referral urogynecological centers between January and June 2011 are presented in a series of cases of mesh complications, which provide an indication of the wide range...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0412.2012.01423.x
更新日期:2012-07-01 00:00:00
abstract::First catch urine (FCU) from 751 asymptomatic adolescent female high school students, with sexual debut, were screened for the presence of Chlamydia trachomatis (Group A). The prevalence of C. trachomatis infection in Group A was 2.1% (16/751). In Group B, 619 asymptomatic adolescent females attending a youth and a fa...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349409013397
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to compare the efficacy and maternal-neonatal morbidity between balloon catheter and oxytocin for induction of labor in women with a previous cesarean section and an unfavorable cervix. MATERIAL AND METHODS:This open-label randomized controlled trial took place in seven French ho...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/aogs.13712
更新日期:2020-02-01 00:00:00
abstract::Oxytocin concentrations increased during pregnancy and during medication with low-dose oral contraceptives (o.c.). Postprandial somatostatin concentrations were lower during medication with o.c. Insulin concentrations were elevated during pregnancy with the same tendency during medication with o.c. Gastrin levels were...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349109007873
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:To investigate the diagnostic efficacy of preoperative lymphoscintigraphy (LS), Ga-67 scintigraphy (GS) and computed tomography (CT) for detection of lymph node metastasis in patients with endometrial or ovarian carcinoma. METHODS:The results of preoperative LS, GS and CT used to detect lymph node metastasi...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract::Acute polyhydramnios in monozygotic twin pregnancy causes severe maternal discomfort and carries a high risk of premature labor. During the years 1980 to 1987, 36 patients with this complication were delivered in Sweden, giving an incidence of 1/20,000 births, or 1/200 twin births. In 18 patients (group A) who were tr...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349009036150
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:Early mother-infant relationships in preterm populations were evaluated in the context of a systematic review of the literature. DESIGN AND SETTING:A systematic search of three electronic databases (PsychINFO, PubMed and Cochrane Library) was undertaken. Three studies of maternal attachment, 18 studies of mo...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1600-0412.2011.01304.x
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Few studies have examined smoking prior to pregnancy and the occurrence of spontaneous abortion, as most studies have addressed the risk of spontaneous abortion in relation to smoking during pregnancy. However, results are not entirely consistent. The aim of the present study was to assess the risk of sponta...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340600589560
更新日期:2006-01-01 00:00:00
abstract::Ovulation-inducing drugs have been widely used for various types of infertility since the beginning of 1960s and their use increases day by day parallel to the success achieved in fertility treatment. However, the researches performed in the last two decades have begun to discuss about the safety of these drugs and th...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.0001-6349.2004.00669.x
更新日期:2004-12-01 00:00:00
abstract::Blood samples from pregnant women and from mothers before and after delivery were tested for the occurrence of feto-maternal bleeding (f.m.b.) using Kleihauers acid-elution technique and a counting technique described by Schneider. It was assumed that f.m.b. had occurred, when there was a clinically significant differ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347709155017
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:To determine whether adequate trophoblastic migration and maternal placental perfusion occurs in cases of early pregnancy loss, we compared vessels in elective abortion decidua with those in spontaneous abortion decidua. METHODS:Elective abortion decidua at 5-11 weeks (n = 40) were compared with spontaneous...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340500501731
更新日期:2006-01-01 00:00:00
abstract:AIMS:To examine per- and postoperative complication rates and efficacy of laser conization in the treatment of cervical intraepithelial neoplasia (CIN) grade II-III. MATERIAL AND METHODS:Eligible for analyses were all women treated with their first laser conization because of CIN II-III during the time-period January ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract::Four patients with endometrial foam cells are described. In one the endometrium was obtained after parturition. It showed decidua and endometritis, whereas in the second patient, who had received birth control medication in the past, the endometrium was proliferative. In both cases there was a considerable amount of e...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348309155791
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVES:To evaluate if calcium supplementation during pregnancy could have any influence on primary dentition measured as the reduction of dental caries of the child. DESIGN:Individual randomized controlled trial. SETTING:One hospital in Rosario, Argentina. POPULATION:Random sample of 195 12-year-old children fro...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016349.2010.518228
更新日期:2010-11-01 00:00:00
abstract::A uterine leiomyoma with a focus of fatty and cartilaginous differentiation in a 58-year-old female is reported. The leiomyoma was located in the posterior uterine wall and had a maximum diameter of about 15 cm. A yellow hard nodule, about 5 cm in diameter, was found in the periphery of the leiomyoma and histologicall...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349309068043
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND AND METHODS:The cesarean section rate for term singleton breech babies in the Netherlands rose from 57 to 81% after the Term Breech Trial in 2000. The Dutch Maternal Mortality Committee registered and evaluated maternal mortality due to elective cesarean section for breech. RESULTS:Four maternal deaths afte...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340601104054
更新日期:2007-01-01 00:00:00