Maternal calcium supplementation during pregnancy and dental caries of children at 12 years of age: follow-up of a randomized controlled trial.

Abstract:

OBJECTIVES:To evaluate if calcium supplementation during pregnancy could have any influence on primary dentition measured as the reduction of dental caries of the child. DESIGN:Individual randomized controlled trial. SETTING:One hospital in Rosario, Argentina. POPULATION:Random sample of 195 12-year-old children from a follow-up study of 614 women who were randomized during pregnancy to calcium supplementation or placebo. METHODS:An independent researcher blinded to the group where the mothers were assigned performed a dental examination of the children. MAIN OUTCOME MEASURES:Proportion of children with at least one decayed, missing or filled teeth (DMFT/dmft) and mean number of decayed, missing or filled surfaces (DMFS/dmfs) per children. RESULTS:Ninety-eight children were assessed in the calcium supplementation group and 97 in the placebo group. 63.3% of the children whose mother took calcium supplementation had at least one DMFT/dmft compared to 86.6% in the placebo group (<0.001). The children whose mother received the intervention had a 27% reduction in the risk of developing at least one DMFT/dmft (RR: 0.73, CI 95%: [0.62; 0.87]). CONCLUSIONS:This study shows a modeling effect of calcium intake during pregnancy on dental caries of the offspring. At around 12 years of age children whose mothers received calcium supplementation when pregnant showed a significant reduction in dental caries.

authors

Bergel E,Gibbons L,Rasines MG,Luetich A,Belizán JM

doi

10.3109/00016349.2010.518228

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1396-402

issue

11

eissn

0001-6349

issn

1600-0412

journal_volume

89

pub_type

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