Menstrual bleeding patterns in pre- and perimenopausal women: a population-based prospective diary study.

Abstract:

BACKGROUND:To investigate natural menstrual bleeding patterns in pre- and perimenopausal women, a prospective observational population study was carried out. METHODS:A total of 1616 (80.8%) of a population-based sample of 2000 Danish women aged 45-54 years answered an initial questionnaire. Of 1059 women with natural gynecological functions, 951 (89.8%) completed 1 year of daily recording of bleeding. Of these women, 592 were pre- or perimenopausal and were included in this study. MAIN OUTCOME MEASURES:Length and heaviness of bleeding episodes, including frequency of spotting, flooding and prolonged bleeding, according to regularity of cycles. RESULTS:The proportion of women with irregular cycles increased from 58.3% at age 45-46 years to 100% at age 53-54 years (P < 0.001). Irregularity of cycles was accompanied by increased variation in both length and subjective assessment of heaviness of bleeding episodes in the individual woman and between women (P < 0.001). Episodes of spotting (P < 0.001) and prolonged bleeding (10 days or more) (P < 0.001) were more common in women with irregular cycles. Subjective assessment of heaviness of bleeding episodes, however, was higher in women with regular cycles (P < 0.001). One or more episodes of flooding were recorded by 24.0% of all women irrespective of regularity of cycles (P = 0.40) but more frequently in younger women (P < 0.001). CONCLUSIONS:Irregularity of cycle lengths at the end of the fertile period is common, and is accompanied by an increased inter- and intraindividual variation in the length and heaviness of bleeding episodes, including increased frequency of prolonged bleeding and spotting.

authors

Astrup K,Olivarius Nde F,Møller S,Gottschau A,Karlslund W

doi

10.1111/j.0001-6349.2004.00401.x

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

197-202

issue

2

eissn

0001-6349

issn

1600-0412

pii

401

journal_volume

83

pub_type

杂志文章
  • Prognosis, recurrences and metastases correlated to histologic cell type in carcinoma of the uterine cervix.

    abstract::An analysis of 230 patients treated with radiotherapy for cervical cancer stages I and II is presented. No positive correlation to cell type was found as regards the number of failures, recurrence rate or the frequency of regional or distant metastases. Although different biological behavior might be shown by cancers ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347609156923

    authors: Johansson O,Johnsson JE,Lindberg JG,Sydsjö A

    更新日期:1976-01-01 00:00:00

  • Allo-immunization during pregnancy. Clinical results from 1983 to 1989 in a Scandinavian university hospital.

    abstract::From 1983 to 1989, 147,068 pregnancies were analyzed for allo-immunization against erythrocyte antigens. Approximately half of the cases were due to immunization against factor D and the others were due to allo-immunization against other antigens (K, c, E, etc.). In 61 cases exchange transfusion of the newborn was nee...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349209021051

    authors: Belfrage P,Thomassen P,Floberg J,Akerblom O,Broberger U

    更新日期:1992-05-01 00:00:00

  • Sex-linked values of E-rosette forming lymphocytes in mother and newborn.

    abstract::The T-cell marker of spontaneous rosettes with sheep erythrocytes was determined in 34 normal term-deliveries on the peripheral lymphocytes of the mother and the corresponding cord-blood lymphocytes of the newborn, immediately after delivery. A consistently lower level of E-rosette forming lymphocytes was observed in ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Halbrecht I,Komlos L,Goldman J

    更新日期:1977-01-01 00:00:00

  • Sonographic dating of pregnancies among women with menstrual irregularities.

    abstract::In order to study the benefit of sonographic dating, 277 women with irregular periods and 264 women with a scanty last bleeding had gestational age and estimated day of delivery (EDD) estimated from both last menstrual period (LMP) and measurement of fetal Biparietal Diameter (BPD) in the second trimester. For the wom...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.3109/00016349109006171

    authors: Waldenström U,Axelsson O,Nilsson S

    更新日期:1991-01-01 00:00:00

  • Cause of and factors associated with stillbirth: a systematic review of classification systems.

    abstract:INTRODUCTION:An estimated 2.6 million stillbirths occur worldwide each year. A standardized classification system setting out possible cause of death and contributing factors is useful to help obtain comparative data across different settings. We undertook a systematic review of stillbirth classification systems to hig...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/aogs.13126

    authors: Aminu M,Bar-Zeev S,van den Broek N

    更新日期:2017-05-01 00:00:00

  • The plasma concentration of medroxyprogesterone acetate and ovarian function during treatment with medroxyprogesterone acetate in 5 and 10 mg doses.

    abstract::Peripheral plasma levels of medroxyprogesterone acetate (MPA) were determined by radioimmunoassay in 5 women after oral administration of 5 and 10 mg medroxyprogesterone acetate daily. Peak levels of MPA in plasma were recorded within 1 - 3 hours of taking the tablet, which indicates a rapid absorption from the gastro...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348409154654

    authors: Wikström A,Green B,Johansson ED

    更新日期:1984-01-01 00:00:00

  • Transvaginal ultrasound, endometrial cytology sampled by Gynoscann and histology obtained by Uterine Explora Curette compared to the histology of the uterine specimen. A prospective study in pre- and postmenopausal women undergoing elective hysterectomy.

    abstract:BACKGROUND:The purpose of this study was to evaluate the diagnostic value of transvaginal ultrasound measurement of endometrial thickness, cytology obtained by Gynoscann, and histology of the endometrium sampled by Uterine Explora Curette compared with histology of the uterine specimen as the gold standard. METHODS:Co...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349709024349

    authors: Kufahl J,Pedersen I,Sindberg Eriksen P,Helkjaer PE,Larsen LG,Jensen KL,de Nully P,Philipsen T,Wåhlin A

    更新日期:1997-09-01 00:00:00

  • Cytogenetic studies in patients with reproductive failure.

    abstract:BACKGROUND:Cytogenetic studies in patients with reproductive failure AIM:To investigate the contribution of chromosomal abnormalities in sub fertility and in couples with repeated abortions. METHODS:Hundred and 13 couples who had at least two or more spontaneous abortions and 65 women and 63 men with infertility were...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2003.820109.x

    authors: Düzcan F,Atmaca M,Cetin GO,Bagci H

    更新日期:2003-01-01 00:00:00

  • The cervical mucus plug: structured review of the literature.

    abstract::The cervical mucus plug is a large, complex structure within the cervical canal that is shed shortly before or during labor. We propose that the cervical mucus plug fulfills critical 'gate-keeper' functions based on its physical and immunologic properties, which help prevent ascending infection and preterm labor. The ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1080/00016340902852898

    authors: Becher N,Adams Waldorf K,Hein M,Uldbjerg N

    更新日期:2009-01-01 00:00:00

  • Rupture of the spleen during delivery.

    abstract::A case of traumatic rupture of a normal spleen in a complicated delivery is presented. The etiology of splenic rupture and therapeutic aspects of this unusual occurrence are discussed. It is pointed out that a violent expression of the fetus might be dangerous for the mother. ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347809155903

    authors: Christau S,Klebe JG

    更新日期:1978-01-01 00:00:00

  • Prenatal course and outcome in 103 cases of fetal spina bifida: a single center experience.

    abstract:OBJECTIVE:To investigate the prenatal course and functional outcome for fetuses with spina bifida according to the level of the spinal lesion at prenatal ultrasound examination. DESIGN:Retrospective, descriptive study. SETTING:Tertiary referral center, Germany. POPULATION:A total of 103 fetuses with spina bifida ide...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349.2010.512062

    authors: Amari F,Junkers W,Hartge D,Beyer DA,Axt-Fliedner R,Weichert J

    更新日期:2010-10-01 00:00:00

  • The #Enzian classification: A comprehensive non-invasive and surgical description system for endometriosis.

    abstract::Advances in preoperative diagnostic as well as surgical techniques for the treatment of endometriosis, especially deep endometriosis call for a classification system that includes all aspects of the disease such as peritoneal, ovarian endometriosis and deep endometriosis and secondary adhesions. The widely accepted r-...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.14099

    authors: Keckstein J,Saridogan E,Ulrich UA,Sillem M,Oppelt P,Schweppe KW,Krentel H,Janschek E,Exacoustos C,Malzoni M,Mueller M,Roman H,Condous G,Forman A,Jansen FW,Bokor A,Simedrea V,Hudelist G

    更新日期:2021-01-23 00:00:00

  • Continuous epidural anaesthesia with a low frequency of instrumental deliveries.

    abstract::The results of 204 cases of regional analgesia by means of continuous epidural block during labour and delivery are reported. The frequency of instrummental intervention using forceps or the vacuum extractor is low, less than 15% for primi- and multi-gravidas combined, although pathological conditions were recognized ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016347509157101

    authors: Maltau JM,Andersen HT

    更新日期:1975-01-01 00:00:00

  • Preferences for involvement in treatment decision-making among Norwegian women with urinary incontinence.

    abstract:BACKGROUND:Current health policies advocate patient participation in treatment decision-making. Objective. To explore whether role preferences among women with urinary incontinence (UI) change depending on the treatment decision-making context. We also explore what factors are associated with role preferences and chang...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016340701622310

    authors: O'Donnell M,Hunskaar S

    更新日期:2007-01-01 00:00:00

  • Effects of thyroxine therapy on bone metabolism in postmenopausal women with hypothyroidism.

    abstract:OBJECTIVE:To evaluate whether thyroid stimulating hormone-suppressive thyroxine replacement therapy increases bone loss in postmenopausal women. MATERIALS AND METHOD:The study had a cross-sectional design. Fifty-four postmenopausal women on long-term treatment with thyroxine for primary hypothyroidism, who showed supp...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349609054714

    authors: Affinito P,Sorrentino C,Farace MJ,di Carlo C,Moccia G,Canciello P,Palomba S,Nappi C

    更新日期:1996-10-01 00:00:00

  • Effect of urinary trypsin inhibitor on potassium currents: fetus modulates membrane excitability by production of UTI.

    abstract:BACKGROUND:Amniotic fluid contains a significant level of urinary trypsin inhibitor (UTI). Previously, we reported that UTI inhibits calcium influx of myometrium and it is effective in preventing uterine contraction. This study examined the effects of UTI upon potassium channels, which is important for membrane excitab...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2004.00268.x

    authors: Takeuchi K,Fukuda A,Kanayama N

    更新日期:2004-01-01 00:00:00

  • Subtle perturbations of genital microflora alter mucosal immunity among low-risk pregnant women.

    abstract:OBJECTIVE:Alteration in the vaginal flora has been associated with adverse pregnancy outcomes. The objective of this study was to examine the impact of changes in individual microflora on genital immunity among low-risk pregnant women in early pregnancy. DESIGN:Cross-sectional study. SETTING:Large, tertiary care, aca...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2011.01082.x

    authors: Anderson BL,Cu-Uvin S,Raker CA,Fitzsimmons C,Hillier SL

    更新日期:2011-05-01 00:00:00

  • Vacuum extraction: is there any need to improve the current training in the UK?

    abstract:OBJECTIVE:The objective of this study was to assess the use and efficacy of delivery by vacuum extraction or ventouse in routine clinical practice and to assess some aspects of the procedure that may reflect the quality of training in this technique. MATERIALS AND METHODS:Women's demographic profiles and delivery deta...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2004.0399.x

    authors: Sau A,Sau M,Ahmed H,Brown R

    更新日期:2004-05-01 00:00:00

  • Serum folate levels in normal full-term pregnant Chinese women.

    abstract::Serum folate levels were determined by a radio-isotopic assay method and then analysed in 253 normal full-term pregnant women. None of them had received any hematonic during their whole pregnancy period. Their mean age was 27.72 years and the mean pregnancy duration was 39.50 weeks. Mean hemoglobin concentration in th...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348809004252

    authors: Ho CH,Yuan CC,Yeh SH

    更新日期:1988-01-01 00:00:00

  • The prognostic value of the miR-200 family in ovarian cancer: a meta-analysis.

    abstract:INTRODUCTION:To assess the association between miR-200 family expression and overall survival/progression-free survival in women with ovarian cancer. MATERIAL AND METHODS:A systematic literature search, up to September 2015, in PubMed, EMBASE and Cochrane Library was performed to identify articles that assessed the as...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/aogs.12883

    authors: Shi C,Zhang Z

    更新日期:2016-05-01 00:00:00

  • Labor induction by vaginal misoprostol in grand multiparous women.

    abstract:BACKGROUND:Grand multiparous women in poor and under-privileged settings run a high risk of uterine rupture at labor induction. The purpose was to elucidate whether vaginal misoprostol medication is a safe and cost-effective alternative induction method in grand multiparous women, in whom, under prevailing circumstance...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Bique C,Bugalho A,Bergström S

    更新日期:1999-03-01 00:00:00

  • Mothering problems and child morbidity amongst "mothers with emotional disturbances".

    abstract::In a study of 1,955 primigravidae who gave birth to a live singleton baby, 227 (11.6%) scored 'positive' (7+) in an antenatal Health Questionnaire enquiring into pre-pregnancy emotional disturbances. This group of mothers had more frequent depression, and this was of longer duration after their delivery compared with ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348809004190

    authors: Nordström UL,Dallas JH,Morton HG,Patel NB

    更新日期:1988-01-01 00:00:00

  • Adiponectin is reduced in gestational diabetes mellitus in normal weight women.

    abstract:BACKGROUND:Adiponectin is an adipose tissue-derived protein counteracting insulin resistance and inflammation. We have compared women with gestational diabetes mellitus (GDM; n = 22) and normal pregnancies (controls; n = 29) to evaluate whether adiponectin represents a link between endocrine function of adipose tissue ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2004.00413.x

    authors: Ranheim T,Haugen F,Staff AC,Braekke K,Harsem NK,Drevon CA

    更新日期:2004-04-01 00:00:00

  • Zinc in Danish women during late normal pregnancy and pregnancies with intra-uterine growth retardation.

    abstract::Zinc and alkaline phosphatase were examined in 41 pregnant women (gestational weeks 35-41) and in 12 women within 24 h of delivery. The serum-zinc level was reduced in all the women, though to a lesser degree in women giving birth to small for gestational age (SGA) babies than in the control mothers. The difference be...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348709022042

    authors: Voss Jepsen L,Clemmensen K

    更新日期:1987-01-01 00:00:00

  • Factors influencing delivery method in breech presentation.

    abstract:BACKGROUND:To study factors influencing delivery method in breech presentation. METHODS:Population based cohort study from The Medical Birth Registry of Norway, comprising all singleton deliveries in Norway, 1967-1994, 1,592,064 deliveries of which 45,921 (2.9%) were in breech presentation. RESULTS:The proportion of ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Albrechtsen S,Rasmussen S,Dalaker K,Irgens LM

    更新日期:1998-04-01 00:00:00

  • Does group training during pregnancy prevent lumbopelvic pain? A randomized clinical trial.

    abstract:BACKGROUND:Prevention of lumbopelvic pain in pregnancy has been sparsely studied. One aim of this study was to assess if a 12-week training program during pregnancy can prevent and/or treat lumbopelvic pain. A randomized controlled trial was conducted at Trondheim University Hospital and three outpatient physiotherapy ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00016340601089651

    authors: Mørkved S,Salvesen KA,Schei B,Lydersen S,Bø K

    更新日期:2007-01-01 00:00:00

  • Hypertensive disorders in pregnancy and later dementia: a Swedish National Register Study.

    abstract:INTRODUCTION:Our aim was to investigate the rate of vascular dementia and dementia in women with previous hypertensive disorders in pregnancy, since white matter lesions of the brain and cardiovascular disease are linked both to dementia and hypertensive disorders in pregnancy. MATERIAL AND METHODS:Prospective populat...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13096

    authors: Andolf EG,Sydsjö GC,Bladh MK,Berg G,Sharma S

    更新日期:2017-04-01 00:00:00

  • Does mode of hysterectomy influence micturition and defecation?

    abstract:OBJECTIVE:Hysterectomy may affect bladder and bowel function. A retrospective study was performed to compare the prevalence of micturition and defecation symptoms between different modes of hysterectomy. METHODS:All pre-operatively asymptomatic patients, with uteral size < or =10 cm, who underwent hysterectomy between...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2001.801012.x

    authors: Roovers JP,van der Bom JG,Huub van der Vaart C,Fousert DM,Heintz AP

    更新日期:2001-10-01 00:00:00

  • Risk of torsion and malignancy by adnexal mass size in pregnant women.

    abstract:OBJECTIVE:To investigate risks of torsion and malignancy by adnexal mass size during pregnancy. DESIGN:Retrospective review of medical records. SETTING:General university hospital and healthcare center. POPULATION:Four hundred and seventy women who underwent surgery for adnexal masses during pregnancy between 2002 a...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1600-0412.2011.01070.x

    authors: Koo YJ,Kim TJ,Lee JE,Kwon YS,Kim HJ,Lee IH,Lim KT,Lee KH,Shim JU,Mok JE

    更新日期:2011-04-01 00:00:00

  • The diagnostic value of amniotic fluid Gram stain examination and limulus amebocyte lysate assay in patients with preterm birth.

    abstract::The purpose of this study was to determine the value of Gram stain examination and Limulus amebocyte lysate (LAL) test in the detection of intraamniotic infection. Ninety women with preterm labor and intact membranes (n = 55) or preterm premature rupture of membranes (PROM) (n = 35) who delivered prematurely were incl...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016349509024449

    authors: Hazan Y,Mazor M,Horowitz S,Leiberman JR,Glezerman M

    更新日期:1995-04-01 00:00:00