Abstract：
OBJECTIVE:To compare 14 patients with gastric ulcer and Helicobacter heilmannii with other patients with gastric ulcer: age and sex matched patients, patients colonized by Helicobacter pylori and patients on nonsteroidal anti-inflammatory drugs (NSAIDs). SETTING:The endoscopy unit of a university-affiliated hospital. PATIENTS AND METHODS:All patients underwent endoscopy with two antral biopsies and smears from biopsies (touch cytology) in addition to biopsies of ulcers. Most patients had fundic biopsies (n = 10), antral biopsies for culture (n = 7) and/or a urease test (n = 9). Serologic determination of antibodies against H. pylori was obtained in nine patients. RESULTS:Patients with H. heilmannii diagnosed on smears from biopsies (touch cytology) had multiple and antral ulcers in 11 samples, and nodular or irregular lesions in five samples. No patient had a history of peptic ulcer disease. Biopsy revealed mild chronic gastritis in all patients, with features of reactive gastritis in nine. No patient had coexistent infection with H. pylori. Only two of ten patients with follow-up endoscopies had persistent H. heilmannii infection on smear or biopsy. No patient had symptomatic recurrence. Patients with H. pylori infection were older and often had recurrent ulceration. The majority of ulcers associated with NSAIDs occurred in elderly women. CONCLUSIONS:Newly diagnosed gastric ulcers are associated with H. heilmannii infection. Healing is associated with the disappearance of H. heilmannii and the regression of reactive gastritis. Ulcers differ from those associated with H. pylori infection or with the use of NSAIDs, suggesting that H. heilmannii is a possible cause of gastric ulcers.
journal_name
Eur J Gastroenterol Hepatoljournal_title
European journal of gastroenterology & hepatologyauthors
Debongnie JC,Donnay M,Mairesse J,Lamy V,Dekoninck X,Ramdani Bdoi
10.1097/00042737-199803000-00011subject
Has Abstractpub_date
1998-03-01 00:00:00pages
251-4issue
3eissn
0954-691Xissn
1473-5687journal_volume
10pub_type
杂志文章abstract：OBJECTIVE:Health expenditure is a marker associated with an advanced healthcare system, which contributes toward the good prognosis of patients. Mortality-to-incidence ratios (MIRs) are one of the predictors that reflect the prognosis of cancer patients. There remains some uncertainty on the correlation of MIRs of live...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000969
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:The quality of Barrett's surveillance relies on an adequate endoscopic inspection, obtaining a sufficient number of biopsy specimens, good communication of the endoscopic findings to the pathologist, and an accurate description of the histological findings by the pathologist. The aim of this study was to asse...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,多中心研究
doi：10.1097/MEG.0b013e3282f8295d
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVES:Liver transplant recipients are often screened for spontaneous bacterial peritonitis during the immediate preoperative evaluation to determine medical fitness to proceed. However, it is unknown whether subclinical spontaneous bacterial peritonitis impacts on post-transplant outcomes. Our aim was to determine...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000473
更新日期：2016-01-01 00:00:00
abstract：:The Maastricht 2 Consensus Report features evidence-based recommendations for the management of Helicobacter pylori infection. Strongly recommended indications for H. pylori eradication include duodenal and gastric ulcer, mucosa-associated lymphoid tissue lymphoma, atrophic gastritis, post gastric cancer resection, fi...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:The number of procedures utilized in the general management of gastrointestinal bleeding (GIB) has not been investigated previously. We used the National Endoscopic Database of the Clinical Outcomes Research Initiative for an observational study to analyze the average length of workup in GIB. METHODS:The el...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000693
更新日期：2016-10-01 00:00:00
abstract：AIM:Many researchers consider portal thrombosis (PT) as a contraindication to transjugular intrahepatic portosystemic shunt (TIPS). The aim of this retrospective study was to compare the feasibility and long-term prognosis of TIPS in cirrhotic patients, with and without, complete PT. PATIENTS AND METHODS:Four hundred ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e328338d995
更新日期：2010-09-01 00:00:00
abstract：:Primary malignant lymphoma of the bowel is a rare complication of inflammatory bowel disease. The association of gastrointestinal lymphoma, inflammatory bowel disease and prior immunosuppression remains unclear. We report the first case of azathioprine-treated ulcerative colitis developing rectal lymphoma. ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200108000-00022
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:With the exception of fungi, microbial infections are rare in the oesophagus. Herein, we aimed to systematically assess the distribution and quantity of different antimicrobial host factors as well as, for the first time, functional mucosal antimicrobial activity in the upper gastrointestinal tract. METHODS...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e3283052ddb
更新日期：2008-12-01 00:00:00
abstract：:A 27-year-old woman with chronic renal failure, who had been treated with chronic ambulatory peritoneal dialysis and had developed sclerosing peritonitis, was admitted to the hospital with intra-abdominal sepsis. In spite of antibiotic therapy, sepsis recurred and was associated with intrahepatic cholestasis. In addit...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199801000-00017
更新日期：1998-01-01 00:00:00
abstract：:The prevalence of food allergy reaches 3% in the adult population. Chronic gastrointestinal allergy is a rare entity: 4.2% of food allergies in adults, and represents 3.2% of all intestinal disorders. Non-specific symptoms are the rule but eosinophilic gastrointestinal disorders are the subject of much interest. Endos...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,评审
doi：10.1097/00042737-200512000-00005
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Hepatitis C virus (HCV) infection places a huge burden on healthcare systems. There is no study assessing the impact of HCV infection on premature deaths in Spain. The aim of this study was to estimate productivity losses because of premature deaths attributable to hepatitis C occurring in Spain dur...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000336
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVE:We assessed the impact of direct-acting antiviral (DAA) therapy on liver fibrosis regression measured by transient elastography (TE) in patients with chronic hepatitis C virus (HCV) infection. PATIENTS AND METHODS:A prospective cohort study was carried out in HCV monoinfected patients with advanced liver fib...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000964
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:Time trend studies in the USA have shown that the incidences of adenocarcinomas of the oesophagus and gastric cardia have risen strongly since the 1970s, whereas the incidence of squamous cell carcinomas of the oesophagus has declined. Earlier, we found that the incidence of these adenocarcinomas also rose in...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e32832ca091
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:PillCam patency capsule (PC) is a novel and radiofrequency identification tag-free device that remains intact in the gastrointestinal tract for 30-33 h after ingestion and then disintegrates. The aim of this study was to determine the clinical relevance of PC combined with abdominal ultrasonography as a reli...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000225
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVE:Spontaneous bacterial peritonitis (SBP) is one of the potentially life-threatening complications in ascitic cirrhotic patients with a mortality rate ranging between 30 and 50%. The improved survival might be explained by a more rapid diagnosis and treatment. The aim of our study was to assess the utility of t...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200406000-00011
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVES:To characterize the antigen specificity of circulating anti-neutrophil cytoplasmic antibodies (ANCAs) in inflammatory bowel disease (IBD). DESIGN:Analysis of the prevalence of circulating ANCAs in patients with ulcerative colitis and Crohn's disease, by both non-specific methods (immunofluorescence against ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：BACKGROUND:Data from studies in patients with nonalcoholic steatohepatitis (NASH) suggest an increased hepatic fatty acid oxidation. We have previously shown higher fasting plasma bile acid concentrations in patients with NASH. In-vivo and in-vitro studies suggest that bile acids by binding to peroxisome proliferator-a...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e328345c8c7
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To investigate the subclinical cardiac morphological and functional modifications in cirrhotic patients according to the stage of liver disease. PATIENTS AND METHODS:One hundred and thirteen cirrhotic patients underwent standard Doppler echocardiography and were compared with healthy individuals. Left ventri...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000340
更新日期：2015-06-01 00:00:00
abstract：:We report the case of a 66-year-old man with chronic hepatitis C and a slowly growing left chest wall mass. Two years after the patient first noticed the mass, it was resected. A diagnosis of hepatocellular carcinoma (HCC) was established. The liver was studied by ultrasound, computed tomography (CT), magnetic resonan...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200107000-00018
更新日期：2001-07-01 00:00:00
abstract：:The case of a patient with Crohn's disease and who presented 4 days after a percutaneous liver biopsy with haematochezia suggestive of an exacerbation of his inflammatory bowel disease is described. Subsequent abdominal ultrasonography revealed free fluid in the peritoneal cavity and around the gallbladder. Haemobilia...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200402000-00018
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:Few studies have been carried out on the trace element status in patients with ulcerative colitis (UC). Many trace elements are critical for the normal development and function of the immune system. This study was conducted in order to assess the serum levels of zinc and copper and the possible interrelation(...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199804000-00010
更新日期：1998-04-01 00:00:00
abstract：:Idiopathic fibrosing pancreatitis is an uncommon condition in children and adolescents of unknown aetiology. This syndrome has been reported in 36 cases so far. To our knowledge none of these cases was definitively associated with Crohn's disease. In this report we describe a young female patient who developed Crohn's...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200012090-00010
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:It is important to stratify patients according to the magnitude of risk for gastric cancer development; the OLGA (Operative Link for Gastritis Assessment) and OLGIM (Operative Link on Gastric Intestinal Metaplasia) staging systems of lesions in the stomach mucosa have been proposed for this purpose. There ar...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000000082
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:COX-2, the inducible isoenzyme, was found to be overexpressed in approximately 85% of colorectal adenocarcinomas, contributing to key steps in tumor development. COX-2 polymorphisms that might modify the levels of protein expression would be anticipated to have a substantial influence on disease phenotype. Th...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e3283352cbb
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Little is known on gallbladder emptying and gallstone composition in the elderly. AIMS AND SUBJECTS: Cross-sectional survey on the prevalence of gallstone disease and associated factors, gallstone characteristics and gallbladder emptying in a population aged > or = 60 years. METHODS:Gallstone number and siz...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-199905000-00004
更新日期：1999-05-01 00:00:00
abstract：:Syndecan expression, or the lack thereof by tumor cells, has been associated with poor prognosis in several types of cancer, including colorectal cancer. Syndecan is a heparan sulfate proteoglycan involved in tumor adhesion, invasion, and metastasis. In addition, the expression of the enzyme heparanase by cancer cells...
journal_title：European journal of gastroenterology & hepatology
pub_type： 评论,杂志文章,评审
doi：10.1097/MEG.0b013e3282fc2660
更新日期：2008-08-01 00:00:00
abstract：AIM:To review the evidence that Helicobacter pylori promotes gastric carcinogenesis, with particular reference to gastric epithelial proliferation. MATERIALS AND METHODS:Gastric epithelial kinetics were reviewed and a series of studies of gastric mucosal proliferation in H. pylori-associated gastritis were performed i...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：OBJECTIVES:Because bacteria represent the sole source of gut hydrogen (H2) and methane (CH4), fasting breath H2 and CH4 gases have been used as markers of colonic fermentation. The presence of carbohydrates in the colonic lumen inhibits gastric and pancreatic secretions, and also influences lower oesophageal sphincter ...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/00042737-200605000-00013
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVES:The hybrid allele of the carboxyl ester lipase gene (CEL-HYB1) is a genetic risk factor for chronic pancreatitis (CP) although the mechanism promoting disease development is largely unknown. Here, we aimed to clinically describe subjects carrying the CEL-HYB1 allele and to elucidate why the protein product i...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0000000000001963
更新日期：2020-10-16 00:00:00
abstract：:Endoscopic ultrasonography-guided fine-needle aspiration cytology (EUS-FNA) may provide full-thickness biopsies, adequate for cytology and histology. In the present case report, we describe the first cases of a rare well-differentiated squamous esophageal carcinoma (verrucous esophageal cancer), finally diagnosed by E...
journal_title：European journal of gastroenterology & hepatology
pub_type： 杂志文章
doi：10.1097/MEG.0b013e3283643dfb
更新日期：2013-12-01 00:00:00
