Abstract:
:Prentice and Sheppard (1995, Biometrika 82, 113-125) proposed a method for estimating relative risks associated with poorly measured exposures using disease rates from multiple populations and exposure and confounding factor data from sample surveys of persons in each population. The method involved an assumption of independence of disease rates across populations, conditional on exposures and confounding factors. Here, this assumption is relaxed by allowing dependencies among the disease rates within a partition of the populations, perhaps defined on the basis of geographic proximity or cultural similarity. Such dependencies could, for example, derive from unmeasured risk factors that are shared among neighboring populations. Dependencies within an element of the partition are modeled by allowing a common correlation between the disease rates of contiguous populations and by inducing correlations between the rates for noncontiguous populations using a multivariate lognormal assumption. Estimating equations are proposed for relative risk parameter estimation, and robustness and efficiency properties are assessed through simulations. The relaxed estimation procedure is shown to yield useful efficiency gains when moderate or strong disease rate dependencies are present, especially when disease rate variances are large relative to binomial variance.
journal_name
Biometricsjournal_title
Biometricsauthors
Anderson AB,Prentice RLsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
1527-40issue
4eissn
0006-341Xissn
1541-0420journal_volume
54pub_type
杂志文章相关文献
BIOMETRICS文献大全abstract::A procedure is given for estimating the ratio of the means of two populations using the data from two independent random samples when the observations are normally distributed with population variances that are related to the population means. ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Multilist capture-recapture methods are commonly used to estimate the size of elusive populations. In many situations, lists are stratified by distinguishing features, such as age or sex. Stratification has often been used to reduce biases caused by heterogeneity in the probability of list membership among members of ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2007.00767.x
更新日期:2007-09-01 00:00:00
abstract::This article proposes a two-stage simultaneous confidence procedure for the comparisons of k pairs of population means, without using multiplicity adjustment of more than two populations. The proposed procedure can be broadly applied to parametric or nonparametric models. It is robust and versatile because its derivat...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2007.00902.x
更新日期:2008-06-01 00:00:00
abstract::Pharmacovigilance systems aim at early detection of adverse effects of marketed drugs. They maintain large spontaneous reporting databases for which several automatic signaling methods have been developed. One limit of those methods is that the decision rules for the signal generation are based on arbitrary thresholds...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2009.01262.x
更新日期:2010-03-01 00:00:00
abstract::Moment methods for analyzing repeated binary responses have been proposed by Liang and Zeger (1986, Biometrika 73, 13-22), and extended by Prentice (1988, Biometrics 44, 1033-1048). In their generalized estimating equations (GEE), both Liang and Zeger (1986) and Prentice (1988) estimate the parameters associated with ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Experimental designs that include repeated measures of binary response variables over time and under different conditions are common in biology. In such settings, it is often desirable to characterize the response pattern over time. When response variables are continuous, this characterization can be made in terms of ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::Experiments that longitudinally collect RNA sequencing (RNA-seq) data can provide transformative insights in biology research by revealing the dynamic patterns of genes. Such experiments create a great demand for new analytic approaches to identify differentially expressed (DE) genes based on large-scale time-course c...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13144
更新日期:2020-03-01 00:00:00
abstract::The first part of the article reviews the Data Augmentation algorithm and presents two approximations to the Data Augmentation algorithm for the analysis of missing-data problems: the Poor Man's Data Augmentation algorithm and the Asymptotic Data Augmentation algorithm. These two algorithms are then implemented in the...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::Many problems that appear in biomedical decision-making, such as diagnosing disease and predicting response to treatment, can be expressed as binary classification problems. The support vector machine (SVM) is a popular classification technique that is robust to model misspecification and effectively handles high-dime...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13365
更新日期:2020-08-31 00:00:00
abstract::We consider a fully model-based approach for the analysis of distance sampling data. Distance sampling has been widely used to estimate abundance (or density) of animals or plants in a spatially explicit study area. There is, however, no readily available method of making statistical inference on the relationships bet...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2009.01265.x
更新日期:2010-03-01 00:00:00
abstract::Detecting changes in longitudinal data is important in medical research. However, the existence of measurement outliers can cause an unexpected increase in the false alarm rate in claiming changes. To reduce the outliers, a new method has been developed. In this scheme, two measures are initially taken and, if they ar...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow-up period, and a standard survival analysis would not always be appropriate. In such situation...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2000.00227.x
更新日期:2000-03-01 00:00:00
abstract::We propose a new criterion for confounder selection when the underlying causal structure is unknown and only limited knowledge is available. We assume all covariates being considered are pretreatment variables and that for each covariate it is known (i) whether the covariate is a cause of treatment, and (ii) whether t...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2011.01619.x
更新日期:2011-12-01 00:00:00
abstract::This article presents a new approach for exploring the distribution of interindividual random effects in nonlinear mixed effect models. The approach introduces a spline function, which transforms an assumed normally distributed interindividual random effect to an arbitrary distribution approximating that of the data. ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::With increasing frequency, epidemiologic studies are addressing hypotheses regarding gene-environment interaction. In many well-studied candidate genes and for standard dietary and behavioral epidemiologic exposures, there is often substantial prior information available that may be used to analyze current data as wel...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2009.01357.x
更新日期:2010-09-01 00:00:00
abstract::Tang, Gnecco, and Geller (1989, Biometrika 76, 577-583) proposed an approximate likelihood ratio (ALR) test of the null hypothesis that a normal mean vector equals a null vector against the alternative that all of its components are nonnegative with at least one strictly positive. This test is useful for comparing a t...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2002.00650.x
更新日期:2002-09-01 00:00:00
abstract::Large amounts of longitudinal health records are now available for dynamic monitoring of the underlying processes governing the observations. However, the health status progression across time is not typically observed directly: records are observed only when a subject interacts with the system, yielding irregular and...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13261
更新日期:2020-03-11 00:00:00
abstract::Estimates of waterfowl demographic parameters often come from resighting studies where birds fit with individually identifiable neck collars are resighted at a distance. Concerns have been raised about the effects of collar loss on parameter estimates, and the reliability of extrapolating from collared individuals to ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341X.2004.00245.x
更新日期:2004-12-01 00:00:00
abstract::Brownie, Boos, and Hughes-Oliver (1990, Biometrics 46, 259-266) suggested a modification to the fixed-effects analysis of variance (ANOVA) F test for use in situations where treatments are likely to affect mean response while simultaneously increasing between-subject variability. These authors suggest that the modifie...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::In the area of ecological research the study of species diversity of a community or population seems to have been fully developed. However, the problem of how the distributions and expectations of the sample diversity indices are affected by the population diversity has received little attention. In this paper we show...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::Computer simulation has been used to compare four methods for calculating confidence intervals for simple rate ratios estimated from cohort studies. The method proposed by Cornfield (1956. In Proceedings of the Third Berkeley Symposium on Mathematical Statistics and Probability. Vol. IV, 135-148) for interval estimati...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract::Because the number of patients waiting for organ transplants exceeds the number of organs available, a better understanding of how transplantation affects the distribution of residual lifetime is needed to improve organ allocation. However, there has been little work to assess the survival benefit of transplantation f...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12084
更新日期:2013-12-01 00:00:00
abstract::Interference occurs when the treatment of one person affects the outcome of another. For example, in infectious diseases, whether one individual is vaccinated may affect whether another individual becomes infected or develops disease. Quantifying such indirect (or spillover) effects of vaccination could have important...
journal_title:Biometrics
pub_type: 杂志文章,随机对照试验
doi:10.1111/biom.12184
更新日期:2014-09-01 00:00:00
abstract::A method is developed for obtaining tree-structured relative risk estimates for censored survival data. The first step of a full likelihood estimation procedure is used in a recursive partitioning algorithm that adopts most aspects of the widely used Classification and Regression Tree (CART) algorithm of Breiman et al...
journal_title:Biometrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-06-01 00:00:00
abstract::Serial dilution assays are widely employed for estimating substance concentrations and minimum inhibitory concentrations. The Poisson-Bernoulli model for such assays is appropriate for count data but not for continuous measurements that are encountered in applications involving substance concentrations. This paper pre...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.1999.01215.x
更新日期:1999-12-01 00:00:00
abstract::Bayesian experimental design for a clinical trial involves specifying a utility function that models the purpose of the trial, in this case the selection of patients for a diagnostic test. The best sample of patients is selected by maximizing expected utility. This optimization task poses difficulties due to a high-di...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.01156.x
更新日期:2009-09-01 00:00:00
abstract::Spatial replication is a common theme in count surveys of animals. Such surveys often generate sparse count data from which it is difficult to estimate population size while formally accounting for detection probability. In this article, I describe a class of models (N-mixture models) which allow for estimation of pop...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341X.2004.00142.x
更新日期:2004-03-01 00:00:00
abstract::We consider a semiparametric inference procedure for data from epidemiologic studies conducted with a two-component sampling scheme where both a simple random sample and multiple outcome- or outcome-/auxiliary-dependent samples are observed. This sampling scheme allows the investigators to oversample certain subpopula...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2006.00612.x
更新日期:2006-12-01 00:00:00
abstract::Jolliffe and Jolliffe (1997, Biometrics 53, 1136-1142) proposed various models for data from an experiment on memory in coal tits. This article describes an alternative model, which fits equally well and which may be simpler to interpret. ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.1999.00660.x
更新日期:1999-06-01 00:00:00
abstract::We consider a semiparametric regression model that relates a normal outcome to covariates and a genetic pathway, where the covariate effects are modeled parametrically and the pathway effect of multiple gene expressions is modeled parametrically or nonparametrically using least-squares kernel machines (LSKMs). This un...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2007.00799.x
更新日期:2007-12-01 00:00:00