Abstract:
STUDY OBJECTIVES:To define the clinical characteristics of the patients showing bronchoscopic findings of bronchial narrowing or obliteration with black pigmentation on overlying mucosa (we named this finding as "anthracofibrosis"), and to determine the association of anthracofibrosis with tuberculosis. PATIENTS AND METHODS:The subjects of this study consisted of 28 patients; 8 men and 20 women, ranging in age from 42 to 86 years. The distinctive clinical features, natures of bronchoscopic lesions, and radiologic findings were analyzed retrospectively and summarized. Bacteriologic studies and results of pathologic examinations were also assessed. RESULTS:Chief complaints were cough (20/28) and dyspnea on exertion (17/28). The abnormal bronchoscopic findings were identified most frequently in the right middle lobe bronchus (n=21/28) while more than one part of the bronchial tree was narrowed in 22 patients. Abnormalities of bronchial airways on CT were associated with peribronchial cuffs of soft tissue or surrounding lymph nodes. In 17 patients, active tuberculous infection was confirmed either bacteriologically (n=15) and/or histologically (n=8). Pathologic study of the lesion obtained by bronchoscopic biopsy or thoracotomy showed dense bronchial and/or peribronchial fibrosis with interspersed black pigments. CONCLUSIONS:These findings strongly suggest that bronchial stenosis or obliteration with anthracotic pigmentation in the mucosa was caused by a fibrotic response to active or old tuberculous infection. To prevent the spread of tuberculosis and avoid unnecessary invasive procedures, detailed examinations for the presence of active tuberculosis should be performed in patients with this unique bronchoscopic finding.
journal_name
Chestjournal_title
Chestauthors
Chung MP,Lee KS,Han J,Kim H,Rhee CH,Han YC,Kwon OJdoi
10.1378/chest.113.2.344subject
Has Abstractpub_date
1998-02-01 00:00:00pages
344-50issue
2eissn
0012-3692issn
1931-3543pii
S0012-3692(16)32413-8journal_volume
113pub_type
杂志文章相关文献
CHEST文献大全abstract::The purpose of this study was to determine the number of procedures necessary to become proficient in flexible fiberoptic bronchoscopic examination. I performed 99 bronchoscopic procedures during a formal training program under the direct supervision of instructors with varying experience. There were no statistical di...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.77.1.65
更新日期:1980-01-01 00:00:00
abstract::A patient complained of angina pectoris nine months after surgical repair of an aortic right atrial fistula and mitral valve replacement. Subsequently, he was shown to have a new obstruction of the ostium of the left main coronary artery. This case illustrates the need to consider this syndrome in the differential dia...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.88.3.471
更新日期:1985-09-01 00:00:00
abstract:BACKGROUND:Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung fu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-0954
更新日期:2013-03-01 00:00:00
abstract::Point-of-care ultrasonography is a key skill for the critical care clinician and is gaining widespread acceptance by clinicians in all areas of medicine. In addition to mastery of image acquisition, image interpretation, and clinical application, intensivists need to be adept with billing for their scanning activity. ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2019.06.006
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of repeated thoracenteses on the fluid characteristics and the levels of various cytokines, including tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-5, IL-6, and IL-8, and of plasminogen activator inhibitor type 1 (PAI-1) and tissue type plasminogen activator in malignant...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.123.4.1188
更新日期:2003-04-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the efficacy of standard medical therapy (ST) and noninvasive mechanical ventilation additional to standard medical therapy in hypercapnic acute respiratory failure (HARF). DESIGN:Single center, prospective, randomized, controlled study. SETTING:Pulmonary medicine directed critical care uni...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.114.6.1636
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Urine output (UO) is a vital sign for critically ill patients, but standards for monitoring and reporting vary widely between ICUs. Careful monitoring of UO could lead to earlier recognition of acute kidney injury (AKI) and better fluid management. We sought to determine if the intensity of UO monitoring is ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2017.05.011
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Glutathione S-transferase (GST) genes are involved in the management of oxidative stress in the lungs. We aimed to determine whether they modify the associations between early life smoke exposure and adverse lung health outcomes. METHODS:The Melbourne Atopy Cohort study (a high-risk birth cohort) enrolled 6...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.chest.2018.08.1079
更新日期:2019-01-01 00:00:00
abstract::Seventy-two healthy young individuals were subjected to controlled, moderate hyperventilation with room air and with 4.9 percent CO2 in air, and monitored electrocardiographically. Significant summed frontal T-wave changes with hyperventilation (sigmaT1,2,3 larger than or equal to 1.5 mm) were observed in 12 patients....
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.67.1.123
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:Morbid obesity produces a variety of ECG alterations, including leftward shifts of the P-wave, QRS, and T-wave axes; disproportionately high frequencies of low QRS voltage; left ventricular hypertrophy and left atrial abnormality; and a high frequency of T-wave flattening in the inferior and lateral leads. T...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.119.2.507
更新日期:2001-02-01 00:00:00
abstract::The treatment of asthma relies on the use of the following two major drug classes: beta(2)-agonists, both short acting and long acting; and corticosteroids (CSs). Although the properties of each drug class are well described, their use in combination delivered either separately or through one device has provided some ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-0354
更新日期:2009-10-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the performance of continuous fiberoptic blood gas monitoring with standard, intermittent blood gas sampling in the measurement of arterial and central venous blood gases during marked hemodynamic changes. DESIGN:Prospective, consecutive, enrollment, experimental study. SETTING:Research lab...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.109.4.1049
更新日期:1996-04-01 00:00:00
abstract:STUDY OBJECTIVES:To compare the oxygen pulse curve (O(2)P-C) as measured during cardiopulmonary exercise testing (CPET) with left ventricular (LV) ejection fraction (LVEF) rest-exercise response as measured by multigated equilibrium (99m)Tc radionuclide cineangiography (MUGA) in patients with different degrees of ische...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.121.3.841
更新日期:2002-03-01 00:00:00
abstract::Nineteen consecutive patients with clinically suspected sarcoidosis underwent 67Ga-scintigraphy prior to transbronchial lung biopsy (TBLB) to determine if 67Ga uptake in lung parenchyma would increase the diagnostic yield of the biopsy procedure. Biopsies were obtained from the areas showing parenchymal uptake on the ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.82.1.7
更新日期:1982-07-01 00:00:00
abstract:BACKGROUND:Failure to reliably diagnose ARDS may be a major driver of negative clinical trials and underrecognition and treatment in clinical practice. We sought to examine the interobserver reliability of the Berlin ARDS definition and examine strategies for improving the reliability of ARDS diagnosis. METHODS:Two hu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2017.11.037
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Inaccurate symptom perception contributes to asthma morbidity and mortality in children and adults. Various methods have been used to quantify perceptual accuracy, including psychophysical (resistive loading) approaches, ratings of dyspnea during induced bronchoconstriction, and in vivo monitoring, but it is...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.06-2140
更新日期:2007-09-01 00:00:00
abstract::The management of congestive heart failure remains an issue of great interest. Encouraging data emerged over the last 2 years supporting the use of multisite pacing in patients with severe congestive heart failure and intraventricular conduction delay. We present a case of acute biventricular pacing in a 81-year old m...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.6.1798
更新日期:2000-06-01 00:00:00
abstract::We reviewed results of 78 diagnostic thoracoscopic examinations of patients with lung cancer and homolateral pleural effusion. The study stresses the main locations of pleural metastasis in cases of lung cancer and correlates these data with the pleural spread from extrathoracic primary neoplasms. Also pointed out is ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.5.649
更新日期:1985-05-01 00:00:00
abstract::A protocol was originally designed to study breathing control during and following cardiac arrest in humans, taking advantage of the period of pulseless ventricular fibrillation (PVF) produced while testing a newly implanted cardioverter-defibrillator device. A patient aged in his 60s with New York Heart Association c...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-2950
更新日期:2013-10-01 00:00:00
abstract:STUDY OBJECTIVE:Low-grade systemic inflammation may cause a chronic catabolic state that may affect trainability in patients with COPD as has been seen previously in healthy elderly. Therefore, the aim of the present study was to study the relationship between baseline circulating levels of inflammatory markers and the...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.5.3183
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Patients with sarcoidosis frequently complain of fatigue, even when sarcoidosis has come into clinical remission. The primary aim of this study was to assess the severity of fatigue in patients with sarcoidosis in clinical remission and to characterize it according to the international criteria for chronic f...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2629
更新日期:2011-08-01 00:00:00
abstract::A 60-year-old laboratory technician developed pulmonary infiltrates consistent with chemical pneumonitis following accidental exposure to a mixture of hydrogen bromide and phosphorus tribromide. A protracted clinical course ensued consistent with bronchiolitis obliterans. These problems may have been avoided if the po...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.1.208
更新日期:1988-07-01 00:00:00
abstract::Eighteen asymptomatic postmenopausal women volunteered to ingest 2 ml of 100-proof vodka per kg of body weight in orange juice on one night and a placebo on another. Overnight sleep monitoring was performed immediately thereafter. Alcohol ingestion caused reduction in total sleep time from 329 to 281 minutes and a dec...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.88.2.181
更新日期:1985-08-01 00:00:00
abstract::Natural killer-cell activity of fresh interstitial pulmonary cell populations from patients with squamous cell and adenocarcinoma of the lung and carcinoma metastatic to the lung was assessed and compared to that of apparently normal lung. No increase in the percentage of lymphoid cell populations was noted in the int...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.91.1.26
更新日期:1987-01-01 00:00:00
abstract:STUDY OBJECTIVES:Community-acquired pneumonia (CAP) is a widespread disease with important implications for health-care systems worldwide. This study investigated direct costs, treatment patterns, and outcomes associated with two patient cohorts hospitalized with CAP. DESIGN:The study design was naturalistic, prospect...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.128.4.2238
更新日期:2005-10-01 00:00:00
abstract::A 40-year-old woman with lymphangiomatosis also had an intrathoracic lymphangioma infection. Since the age of 8 years, the patient had undergone repeated abdominal and mediastinal cyst surgeries and had received a diagnosis of lymphangiomatosis. At this time, she showed a high fever of 38.5°C. Cultures of both blood a...
journal_title:Chest
pub_type:
doi:10.1016/j.chest.2020.06.048
更新日期:2020-11-01 00:00:00
abstract::Malignant mesothelioma is an uncommon and usually fatal cancer, for which there is no standard treatment. However, surgical resection remains the mainstay of treatment because of the inability to treat the entire hemithorax effectively with radiation and the lack of effective chemotherapy drugs. Extrapleural pneumonec...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.4_supplement.382s
更新日期:1993-04-01 00:00:00
abstract::Cardiovascular complications from cocaine use have been recognized in increasing frequency in recent years. We report the case of a young man with a history of intranasal cocaine use presenting with acute congestive heart failure who, on postmortem examination, was found to have idiopathic hemochromatosis. It is specu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.92.2.374
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND:In daily clinical work, we often face delayed or recurrent pneumothorax after radiofrequency (RF) ablation for lung tumors, but a large study on this theme has not been done. Thus, we examined the rate of delayed or recurrent pneumothorax after RF ablation for lung tumors and the risk factors associated with...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.08-1499
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Mepolizumab was the first licensed anti-IL5 monoclonal antibody for severe eosinophilic asthma (SEA). To date there are few data to confirm its efficacy in the real-world setting or assessment of baseline characteristics associated with response. RESEARCH QUESTION:How do patients with severe eosinophilic as...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.03.042
更新日期:2020-08-01 00:00:00