Abstract:
:We localized the neuroanatomical correlates for control of saccadic eye movements and for finger movements using a combined transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) approach. Two participants underwent TMS while performing an endogenous saccade task. The motor hand area was localized by TMS and the region anterior to it was mapped to identify the borders of a region where TMS produced delays in generating contralateral saccades. MRI scans were then obtained with fiducial markers placed over the motor hand area and 2 cm anterior to it, the common cortical region that produced saccadic delays in these two subjects. It was also shown that the structural anatomy of the hand area, physiologically defined by visible contractions of the contralateral hand following TMS, corresponded to the knob-like structure recently reported [18, 19]. These results demonstrate that TMS can be a precise, non-invasive tool for neuroanatomical mapping of cortical structures when combined with structural images of the brain.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Ro T,Cheifet S,Ingle H,Shoup R,Rafal Rdoi
10.1016/s0028-3932(98)00097-9subject
Has Abstractpub_date
1999-02-01 00:00:00pages
225-31issue
2eissn
0028-3932issn
1873-3514pii
S0028393298000979journal_volume
37pub_type
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