当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Production of inhibin A and inhibin B in human ovarian sex cord stromal tumors.

Production of inhibin A and inhibin B in human ovarian sex cord stromal tumors.

Abstract：

OBJECTIVE:Our purpose was to examine the cellular localization of inhibin subunits and messenger ribonucleic acid expressions for the inhibin subunits and the serum levels of inhibin A and inhibin B in human ovarian sex cord stromal tumors. STUDY DESIGN:We examined the immunohistochemical localization of the inhibin subunits and the expression of the corresponding messenger ribonucleic acids by Northern blot analysis in a granulosa cell tumor and a Sertoli-Leydig cell tumor. We also measured serum concentrations of dimeric inhibin A and inhibin B by two-site enzyme-linked immunosorbent assay. RESULTS:Immunostaining specific for the inhibin alpha, betaA, and betaB subunits was observed in the granulosa cell tumor. In the Sertoli-Leydig cell tumor we observed immunostaining specific for the alpha subunit in Leydig tumor cells and that specific for the betaA subunit in Sertoli tumor cells and that specific for the betaB subunit in both tumor cells. Northern blot analysis revealed the presence of messenger ribonucleic acids for the alpha, betaA, and betaB subunits in the granulosa cell tumor and the Sertoli-Leydig cell tumor. The serum levels of dimeric inhibin A and inhibin B in patients were elevated preoperatively and decreased progressively after surgery. CONCLUSION:Our results suggest that inhibin A and inhibin B are produced by the human sex cord stromal tumors and that inhibins might be the useful markers of the tumors.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Yamashita K,Yamoto M,Shikone T,Minami S,Imai M,Nishimori K,Nakano R

doi

10.1016/s0002-9378(97)70090-5

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

1450-7

issue

6

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(97)70090-5

journal_volume

177

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • Effect of maternal docosahexaenoic acid supplementation on postpartum depression and information processing.

    abstract：OBJECTIVE:The purpose of this study was to determine the effect of docosahexaenoic acid supplementation on plasma phospholipid docosahexaenoic acid content and indices of depression and information processing for women who breast-feed. STUDY DESIGN:Mothers who planned to breast-feed their infants were assigned randoml...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mob.2003.275

    authors： Llorente AM,Jensen CL,Voigt RG,Fraley JK,Berretta MC,Heird WC

    更新日期：2003-05-01 00:00:00

  • Use of the fetal chest in estimating fetal weight.

    abstract：OBJECTIVE:This study was designed to develop formulas using the chest circumference instead of the abdominal circumference for estimating fetal weight. STUDY DESIGN:Ultrasonographic measurements of the chest circumference, biparietal diameter, abdominal circumference, humeral length, and femoral length were obtained i...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)91427-6

    authors： Winn HN,Rauk PN,Petrie RH

    更新日期：1992-08-01 00:00:00

  • Perinatal observations in a high-risk population managed without intrapartum fetal pH studies.

    abstract：:Intrapartum fetal scalp blood pH studies remain controversial in obstetrics. Electronic fetal monitoring, by contrast, has achieved nearly uniform acceptance. Controlled comparative studies from one institution are unlikely to provide adequate numbers. Intrapartum fetal monitoring is used consistently at our instituti...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(84)90233-3

    authors： Perkins RP

    更新日期：1984-06-01 00:00:00

  • Menstrual cycle-specific inhibition of the proliferation of endometrial stromal cells by interleukin 6 and its soluble receptor.

    abstract：OBJECTIVE:This study investigated the possible roles of interleukin 6 and soluble interleukin 6 receptor in the growth of endometrial and endometriotic cells. STUDY DESIGN:Endometrial and endometriotic stromal cells were collected from the uterus or from ovarian chocolate cysts. We examined the effects of interleukin ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70599-5

    authors： Yoshioka H,Harada T,Iwabe T,Nagano Y,Taniguchi F,Tanikawa M,Terakawa N

    更新日期：1999-05-01 00:00:00

  • Effects of plasma on the platelet antiaggregatory action of prostacyclin in pregnancy.

    abstract：:Platelet-poor plasma from 13 nonpregnant, 33 normally pregnant, and eight preeclamptic women was incubated with prostacyclin. The ability of platelet-poor plasma to diminish the antiaggregatory effect of prostacyclin was assessed by measuring this effect on arachidonic acid-induced platelet aggregation. Platelet aggre...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(87)90370-x

    authors： Baker VV,Kort B,Cefalo RC

    更新日期：1987-04-01 00:00:00

  • No evidence for lipid peroxidation in severe preeclampsia.

    abstract：OBJECTIVE:This study was undertaken to address the role of oxidative stress in preeclampsia. STUDY DESIGN:We measured urinary 8,12-iso-iPF(2alpha)-VI, a chemically stable, free-radical catalyzed product, in a case control study of severe preeclampsia nested within the trial of Calcium for Preeclampsia Prevention. Case...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.116754

    authors： Regan CL,Levine RJ,Baird DD,Ewell MG,Martz KL,Sibai BM,Rokach J,Lawson JA,Fitzgerald GA

    更新日期：2001-09-01 00:00:00

  • Chorionic villus sampling by rigid forceps: experience with 300 cases at risk for thalassemia major.

    abstract：:In this article we report the results of chorionic villus sampling by a biopsy forceps inserted via the cervix under ultrasonic guidance in 300 pregnancies at risk for thalassemia major. A sufficient amount of chorionic villi for deoxyribonucleic acid analysis by oligonucleotide hybridization was obtained in all cases...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(87)90352-8

    authors： Monni G,Ibba RM,Olla G,Rosatelli C,Cao A

    更新日期：1987-04-01 00:00:00

  • Factors that predict low hematocrit levels in the postpartum patient after vaginal delivery.

    abstract：OBJECTIVE:The purpose of this study was to provide a viable alternative to routine postpartum hematocrit measurement, by a determination of the clinical risk factors that identify patients with anemia and an examination of the resulting cost savings. STUDY DESIGN:In this retrospective review, cases (postpartum hematoc...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.121255

    authors： Petersen LA,Lindner DS,Kleiber CM,Zimmerman MB,Hinton AT,Yankowitz J

    更新日期：2002-04-01 00:00:00

  • The effects of an antihistamine and/or a glucocorticoid on the prolactin response to surgical procedures.

    abstract：:Prolactin (PRL) release in response to surgical stress has been demonstrated in a variety of species. Previous studies in rats indicate this response is blunted or blocked by pretreatment with either glucocorticoids or antihistamines. The present study was designed to investigate this phenomenon in man. Serum PRL leve...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-9378(78)90769-x

    authors： Chapler FK,Sherman BM,Swanson JA

    更新日期：1978-10-15 00:00:00

  • Risk factors for early death among extremely low-birth-weight infants.

    abstract：OBJECTIVE:The purposes of this study were to compare the clinical characteristics of extremely low birth-weight infants (501-1000 g birth weight) who die early (<12 hours of age) with those of infants who die >12 hours after birth and infants who survive to neonatal intensive care unit discharge and to develop a model ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.121652

    authors： Shankaran S,Fanaroff AA,Wright LL,Stevenson DK,Donovan EF,Ehrenkranz RA,Langer JC,Korones SB,Stoll BJ,Tyson JE,Bauer CR,Lemons JA,Oh W,Papile LA

    更新日期：2002-04-01 00:00:00

  • Gallbladder disease in pregnancy.

    abstract：:Cholecystosonography was performed on 338 obstetric patients, and the gallbladder was successfully visualized in 93% of them. Gallbladder volume increased with duration of pregnancy. Three and one-half percent of the patients had obvious cholelithiasis, and a total of 4.2% had abnormalities. These findings suggest tha...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90434-3

    authors： Stauffer RA,Adams A,Wygal J,Lavery JP

    更新日期：1982-11-15 00:00:00

  • Placental prostaglandin levels in pre-eclampsia.

    abstract：:Pre-eclampsia is characterized by uteroplacental ischemia. Prostaglandins can alter systemic blood pressure as well as regulate blood flow to the fetoplacental unit. In the present study, levels of prostaglandin E were significantly decreased in placental tissue from pre-eclamptic patients. Prostaglandin F, a potent v...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(76)90478-6

    authors： Demers LM,Gabbe SG

    更新日期：1976-09-01 00:00:00

  • Expression of a retinol dehydrogenase (hRoDH-4), a member of the retinol/steroid dehydrogenase family implicated in retinoic acid biosynthesis, in normal and neoplastic endometria.

    abstract：OBJECTIVE:Retinoic acid plays an essential role in epithelial differentiation, and retinoid homeostasis is disrupted in cancers of epithelial origin. The goal of this study was to determine whether hRoDH-4, an enzyme that can catalyze the first and rate-limiting step in retinoic acid biosynthesis, is expressed in norma...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.122127

    authors： Cain JM,Zaino R,Shearer D,Bennett RA,Olt G,Weisz J

    更新日期：2002-04-01 00:00:00

  • Uterine prolapse complicated by endometrial cancer.

    abstract：OBJECTIVE:An infrequent clinical dilemma arises when a patient with uterine prolapse that is best treated vaginally is discovered to have coexisting endometrial cancer. Often the underlying cancer is only discovered intraoperatively or postoperatively. We have reviewed our experience in this situation in an effort to e...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/0002-9378(95)91399-8

    authors： Cliby WA,Dodson MK,Podratz KC

    更新日期：1995-06-01 00:00:00

  • Impaired KATP channel function in the fetoplacental circulation of patients with type 1 diabetes mellitus.

    abstract：OBJECTIVE:The increased perinatal morbidity in diabetes may be partly related to vascular dysfunction. Because potassium channels play an important role in the regulation of vascular tone, this study explores the impact of diabetes on potassium channel function in the fetoplacental vascular bed. STUDY DESIGN:Vascular ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.09.031

    authors： Bisseling TM,Versteegen MG,van der Wal S,Copius Peereboom-Stegeman JJ,Borggreven JM,Steegers EA,van der Laak JA,Russel FG,Smits P

    更新日期：2005-03-01 00:00:00

  • Severity of pelvic inflammatory disease as a predictor of the probability of live birth.

    abstract：OBJECTIVE:Our aim was to study the association between severity of pelvic inflammatory disease at laparoscopy and the probability of achieving a live birth, while accounting for subsequent episodes of pelvic inflammatory disease. STUDY DESIGN:Beginning in 1960 a cohort of 1288 women in Lund, Sweden, who had clinical s...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(98)70534-4

    authors： Lepine LA,Hillis SD,Marchbanks PA,Joesoef MR,Peterson HB,Westrom L

    更新日期：1998-05-01 00:00:00

  • Three-millennium antiquity of the lithokelyphos variety of lithopedion.

    abstract：:Identification of a 3100-year-old lithopedion in the Archaic Southwest antedates its first clinical notation by 2100 years. It was only the "autopsy" of time (excavation of the site) that allowed its presence to be brought to light. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 历史文章,杂志文章

    doi：10.1016/0002-9378(93)90148-c

    authors： Rothschild BM,Rothschild C,Bement LC

    更新日期：1993-07-01 00:00:00

  • Use of Norplant contraceptive implants in the immediate postpartum period: safety and tolerance.

    abstract：OBJECTIVE:Our purpose was to determine the safety and tolerance of levonorgestrel contraceptive implants (Norplant, Wyeth-Ayerst, Philadelphia) when inserted immediately post partum, to document the effects on weight and blood pressure, and to determine the side effects. STUDY DESIGN:After vaginal delivery, 250 women ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-9378(95)90109-4

    authors： Phemister DA,Laurent S,Harrison FN Jr

    更新日期：1995-01-01 00:00:00

  • Transient umbilical cord occlusion causes hippocampal damage in the fetal sheep.

    abstract：OBJECTIVE:The purpose of our study was to examine the neuronal outcome after a standardized period of umbilical cord occlusion. STUDY DESIGN:The umbilical cord was clamped for 10 minutes in nine experimental and four control chronically instrumented fetal sheep. Three days later the animals were killed for histologic ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)91728-1

    authors： Mallard EC,Gunn AJ,Williams CE,Johnston BM,Gluckman PD

    更新日期：1992-11-01 00:00:00

  • Burnout in chairs of obstetrics and gynecology: diagnosis, treatment, and prevention.

    abstract：OBJECTIVE:The purpose of this study was to determine the prevalence of burnout in chairs of academic departments of obstetrics and gynecology, identify important stressors, and develop strategies to treat and prevent burnout. STUDY DESIGN:We performed a cross-sectional study of 131 chairs in the United States and Puer...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.122391

    authors： Gabbe SG,Melville J,Mandel L,Walker E

    更新日期：2002-04-01 00:00:00

  • Who returns for postpartum glucose screening following gestational diabetes mellitus?

    abstract：OBJECTIVE:The objective of the study was to determine the prevalence of postpartum impaired glucose regulation (IGR) and factors associated with glucose screening following gestational diabetes mellitus (GDM). STUDY DESIGN:This was a prospective cohort study of 707 women with GDM who delivered at the University Hospit...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2007.09.015

    authors： Hunt KJ,Conway DL

    更新日期：2008-04-01 00:00:00

  • Unrecognized small vesicovaginal fistula as a cause of persistent urinary incontinence.

    abstract：:Three cases of persistent urinary incontinence from unrecognized small vesicovaginal fistula after abdominal hysterectomy for benign gynecologic disease are presented. Visualization of urine in the posterior fornix was suggestive; diagnosis was confirmed by methylene blue test and cystoscopy. Two patients had undergon...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90129-9

    authors： Drutz HP,Mainprize TC

    更新日期：1988-02-01 00:00:00

  • Oxygenation in fetal lambs supported by extrauterine right atrium to artery extracorporeal membrane oxygenation.

    abstract：OBJECTIVE:Our purpose was to determine the adequacy of oxygenation, particularly cranial and cardiac oxygenation, in exteriorized fetal lambs on right atrium to artery extracorporeal membrane oxygenation. STUDY DESIGN:Thirteen fetal lambs were placed on right atrium to artery extracorporeal membrane oxygenation betwee...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(96)70423-4

    authors： Kamimura T,Murata Y,Quilligan EJ,Ibara S,Fujimori K,Nakamura Y,Sakamoto H

    更新日期：1996-02-01 00:00:00

  • Use of alcohol-free antimicrobial mouth rinse is associated with decreased incidence of preterm birth in a high-risk population.

    abstract：OBJECTIVE:We sought to determine if treatment of periodontal disease during pregnancy with an alcohol-free antimicrobial mouth rinse containing cetylpyridinium chloride impacts the incidence of preterm birth (PTB) in a high-risk population. STUDY DESIGN:This single-blind clinical trial studied pregnant women (6-20 wee...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2011.07.016

    authors： Jeffcoat M,Parry S,Gerlach RW,Doyle MJ

    更新日期：2011-10-01 00:00:00

  • Influence of ionizing radiation on fetoplacental growth in mice.

    abstract：:The effects of single doses of 60Co whole-body irradiation were studied in about 600 inbred primiparous Swiss-Webster mice on gestational day 9, 10, 11, or 12. The embryos and their placentas were weighted from day 13 to 18. A reference model surveyed the response of the conceptus to varying doses. A significant reduc...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(75)90889-3

    authors： Philippe JV

    更新日期：1975-11-15 00:00:00

  • The effect of donor and recipient race on outcomes of assisted reproduction.

    abstract：BACKGROUND:A growing literature suggests that minority races, particularly Black women, have a lower probability of live birth and higher risk of perinatal complications after autologous assisted reproductive technology. However, questions still remain as to whether these racial disparities have arisen because of assoc...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2020.09.013

    authors： Liu Y,Hipp HS,Nagy ZP,Capelouto SM,Shapiro DB,Spencer JB,Gaskins AJ

    更新日期：2020-09-12 00:00:00

  • Unsuspected subclinical pregnancies in patients with luteal phase defects.

    abstract：:Patients with different types of luteal phase defects were studied with the use of the radioimmunoassay for the beta subunit of human chorionic gonadotropin (hCG) to determine if unsuspected subclinical pregnancies were more common in a particular type of defect. A type I luteal phase defect is always characterized by...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(16)33086-1

    authors： Cline DL

    更新日期：1979-06-15 00:00:00

  • Ultrasonic ratio of fetal thoracic to abdominal circumference: an association with fetal pulmonary hypoplasia.

    abstract：:Real time ultrasound was used in pregnant women who were considered to be at risk for development of pulmonary hypoplasia (n = 26). The population consisted of women who had either premature rupture of membranes (n = 16) or oligohydramnios (n = 10). The ratio calculated by comparing the fetal thoracic circumference to...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(87)80046-7

    authors： Johnson A,Callan NA,Bhutani VK,Colmorgen GH,Weiner S,Bolognese RJ

    更新日期：1987-09-01 00:00:00

  • Nitrous oxide amniodistention compared with fluid amniodistention reduces operation time while inducing no changes in fetal acid-base status in a sheep model for endoscopic fetal surgery.

    abstract：OBJECTIVE:Our purpose was to evaluate in a sheep model for endoscopic fetal surgery the impact of nitrous oxide-gas amniodistention compared with fluid amniodistention on duration of surgery, hemorrhagic events, and fetomaternal acid-base status. STUDY DESIGN:Pregnant ewes (n = 16) at 92 to 104 days of gestation (term...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.120482

    authors： Gratacós E,Wu J,Devlieger R,Bonati F,Lerut T,Vanamo K,Deprest JA

    更新日期：2002-03-01 00:00:00

  • The management of acardiac twins: a conservative approach.

    abstract：OBJECTIVE:Optimal management of acardiac twin pregnancies is controversial. Data suggest a 50% mortality rate in the "pump" twin when the pregnancy is managed expectantly. Because of increased antenatal diagnosis, outcomes in expectantly managed cases may be better than reported. Our objective was to determine the outc...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/s0002-9378(03)00597-0

    authors： Sullivan AE,Varner MW,Ball RH,Jackson M,Silver RM

    更新日期：2003-11-01 00:00:00