Abstract:
BACKGROUND:Among patients with pulmonary disease due to Mycobacterium avium complex (MAC) seen recently at our center, a substantial number have had extensive calcified mediastinal, hilar, and peribronchial lymphadenopathy, a finding historically inconsistent with pulmonary MAC disease. METHOD:We retrospectively studied the frequency of calcified lymphadenopathy in the chest and prevalence of known risk factors for MAC infection in 79 patients with pulmonary MAC disease who were referred to our hospital over a 1-year period. RESULTS:Calcified intrathoracic adenopathy was present in 25 of the 79 patients (32%). Residential histories revealed that 20 of the 25 patients (80%) with such calcified chest adenopathy reported living for substantial periods in the regions indigenous for Histoplasma capsulatum. In contrast, the residences of patients without calcified chest adenopathy were more evenly distributed throughout the country. Nineteen of these 25 patients (76%) with calcified chest adenopathy had no known predisposing risk factor for the infection; in contrast, the proportion of patients with no calcified adenopathy who also had no identifiable classic risk factor tended to be lower (32/54, 59%). CONCLUSION:In this retrospective study, we observed that (1) a large number of patients with pulmonary MAC disease had no identifiable risk factor, (2) calcified chest adenopathy was present in one third of the patients, (3) the residential history of those with calcified adenopathy mirrored the endemic region of histoplasmosis, and, (4) conversely, those patients with pulmonary MAC who lived outside the histoplasmosis belt had no such adenopathy. Thus, we hypothesize that previous fungal infection may predispose the lungs of certain patients to subsequent invasion by MAC, presumably by airway distortion and/or parenchymal damage.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Chan ED,Iseman MDdoi
10.1097/00007611-199906000-00005subject
Has Abstractpub_date
1999-06-01 00:00:00pages
572-6issue
6eissn
0038-4348issn
1541-8243journal_volume
92pub_type
杂志文章abstract::The diagnosis of primary subclavian axillary venous thrombosis (SAVT) was evaluated in eight patients to compare the accuracy of clinical diagnosis and noninvasive vascular evaluation with phlebography. Clinical evaluation led to three misdiagnoses: lymphedema (1), and inflammatory breast carcinoma (2). Doppler ultras...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198011000-00025
更新日期:1980-11-01 00:00:00
abstract::A phase II study of doxorubicin (Adriamycin)-based induction chemotherapy followed by cyclophosphamide/BCNU (CyBCNU) intensification and autologous bone marrow transplantation (ABMT) was conducted in 20 consecutive women with hormone-resistant metastatic breast cancer referred to our center. Of these 20 women, aged 24...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-199503000-00015
更新日期:1995-03-01 00:00:00
abstract::Granular cell tumors (GCT) are rare, usually benign neoplasms of Schwann cell origin. Since discovery in 1926, fewer than 80 cases of GCT involving the lung have been reported. This report presents a 45-year-old male who presented with symptoms consistent with chronic pancreatitis associated with night sweats, weight ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000182134.44098.01
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:This study seeks to determine the effect of the Texas motorcycle helmet law on fatalities since the repeal of the universal helmet law in 1997. METHODS:Texas monthly motorcycle accident data between 1994 and 2004 were obtained from the National Highway Transportation Safety Administration's Fatality Analysi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181c35653
更新日期:2010-01-01 00:00:00
abstract::A retrospective review of all admissions to the University of Kentucky Medical Center from 1977 to 1987 revealed six persons in whom splenic vein thrombosis could be documented. The patients had either upper gastrointestinal bleeding from gastroesophageal varices or abdominal pain. Pancreatic disease was present in fi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199004000-00014
更新日期:1990-04-01 00:00:00
abstract::A group of 251 randomly selected physicians completed a survey designed to study their attitudes toward, knowledge about, and use of pneumococcal vaccine. Eighty-five percent of respondents believed the vaccine had been proven effective. For the use of the vaccine, respondents supported broad indications, including ch...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198404000-00010
更新日期:1984-04-01 00:00:00
abstract::Chronic mucocutaneous candidiasis is a heterogeneous group of immunodeficiencies associated with persistent candidal infections. Patients with chronic mucocutaneous candidiasis are rarely associated with systemic infections caused by other fungi, but almost never by Candida. The authors report a case of a 16-year-old ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-200408000-00024
更新日期:2004-08-01 00:00:00
abstract::Castleman disease (CD) is a rare lymphoproliferative disorder that occurs in adults and rarely in the pediatric population. The disease is characterized by slowly enlarging masses that can form anywhere within the lymphatic system. It is an uncommon cause of a neck mass in both children and adults that presents insidi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000406
更新日期:2016-02-01 00:00:00
abstract::Human monocytic ehrlichiosis (HME) is a tick-borne disease transmitted during the summer months in the mid-Atlantic, southeastern and south-central United States. A large proportion of patients presenting with ehrlichiosis must be hospitalized because of the severity of their presenting signs, symptoms and lab abnorma...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31804aa1ad
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVES:Inclusion of select orthopedic problems in the orthopedics observation unit (OOU) may reduce hospital admissions. Our system allows OOU status for 24 hours, but the effect on admissions is unknown. Our primary hypothesis was that we could predict which OOU patients required admission based on the presence of...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000181
更新日期:2014-10-01 00:00:00
abstract::A marked increase in the number of cases of shigellosis was reported in Kentucky in 1988. To examine reasons for this increase, we reviewed the 389 cases of shigellosis reported from 1986 through 1989. Ninety-three percent (285/305) of cases due to known species were due to Shigella sonnei. Sixty-two percent (243/389)...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199107000-00002
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVES:Historically, surgical management of empyema was performed predominantly via open thoracotomy; however, during the past decade the use of video-assisted thoracoscopic surgery (VATS) as an alternative has increased. This study retrospectively compared the outcomes and management of patients with empyema at th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000226
更新日期:2015-01-01 00:00:00
abstract::We retrospectively analyzed experience with total gastrectomy (TG) for gastric carcinoma in 23 patients. The TNM stage was I in one patient, II in one patient, III in eight patients, and IV in 13. Linitis plastica was found in ten patients. The operation was considered curative in only eight patients (35%). There were...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00011
更新日期:1989-08-01 00:00:00
abstract::We discuss the cases of four immigrant workers in whom lead intoxication developed via inhalation while they were cutting steel beams removed from a dismantled bridge. They all had toxic lead levels with symptoms and received chelation therapy; the therapy was followed by a decrease in blood lead levels. Rebound incre...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199407000-00003
更新日期:1994-07-01 00:00:00
abstract::Over a period of one year, 1986-1987, 116 strains of Staphylococcus aureus were isolated from patients attending two outpatient dermatology clinics in Houston, Texas. The purpose of this study was to evaluate the adequacy of routine antibiotic sensitivity testing methods for detecting methicillin-resistant Staphylococ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198902000-00005
更新日期:1989-02-01 00:00:00
abstract::We have discussed the pathology of the diverse, numerous neoplasms associated with the central and peripheral types of von Recklinghausen's disease, as exemplified by two case reports. While overlap can occur between these two major types, characteristically this does not occur. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198008000-00036
更新日期:1980-08-01 00:00:00
abstract:BACKGROUND:Recent studies on the impact of rib fractures after blunt trauma have shown a linear relationship between age, increasing number of rib fractures, and complications, including mortality. Others have documented that age-related morbidity increases before age 65 in trauma patients. We hypothesize that patients...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000203815.29757.d3
更新日期:2006-04-01 00:00:00
abstract::We have described a patient with vaccinia necrosum after smallpox vaccination for persistent herpes labialis. The patient eventually recovered after surgical resection of the lesion and multiple courses of vaccinia immune globulin and methisazone. This report emphasizes the needless risks of vaccinating patients with ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198103000-00044
更新日期:1981-03-01 00:00:00
abstract::A 64-year-old female patient presented with acute cerebellar ataxia. After ruling out vascular, infectious, metastatic, demyelinating, and medication etiologies, a paraneoplastic origin for her illness was determined. A renal mass was discovered and found to be renal cell carcinoma. Her symptoms resolved after a radic...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31816bea80
更新日期:2008-05-01 00:00:00
abstract::The ability of Clonorchis sinensis to cause severe hepatobiliary disease is illustrated by the case we have reported, in which biliary obstruction and hepatic fibrosis resulted from the pathologic process associated with chronic clonorchiasis. Immunodiagnostic tests are currently limited, and diagnosis, as illustrated...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198707000-00030
更新日期:1987-07-01 00:00:00
abstract::Insomnia disorder is present in as much as 30% of the general adult population. Given the significant adverse effects of pharmacotherapy, cognitive behavioral therapy (CBT) has been found to be an effective alternative in individuals with insomnia. CBT for insomnia (CBTi) encompasses sleep hygiene, stimulus control, s...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000769
更新日期:2018-02-01 00:00:00
abstract::This descriptive study prospectively examined the performance and supervision of interpretive and procedural skills during an internal medicine clerkship. Students (N = 150) documented having done 7 required and 12 elective skills. Preceptors of required skills were interns (44%), residents (29%), attending physicians...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199606000-00009
更新日期:1996-06-01 00:00:00
abstract::Because household surveys are expensive and time consuming, determination of state or local family planning needs is based on national household survey estimates of contraceptive use rather than state-specific estimates. In June 1982, the University of Georgia Survey Research Center invited the Georgia Department of H...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198503000-00022
更新日期:1985-03-01 00:00:00
abstract::Anorexia nervosa has been associated with various hematologic and immunologic abnormalities, including characteristic bone marrow changes, red cell acanthocytosis, leukopenia, complement deficiencies, and defective bactericidal activity of granulocytes. Dietary and psychogenic factors may play a role in these abnormal...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198308000-00018
更新日期:1983-08-01 00:00:00
abstract:OBJECTIVES:Pulmonary arterial hypertension (PAH) is a progressive disease that can be treated with several medications. Macitentan, an endothelin receptor antagonist (ERA), has received approval as a PAH therapy. We report our data regarding the tolerability in patients with PAH who were switched from bosentan to macit...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000607
更新日期:2017-03-01 00:00:00
abstract::We retrospectively reviewed the charts of 190 hospitalized patients who had human immunodeficiency virus (HIV) antibody testing at our medical center in 1986 and 1987. From 1986 to 1987, HIV antibody testing increased fourfold based on total hospital discharges. Nine patients (5%) tested positive by enzyme immunoassay...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199001000-00008
更新日期:1990-01-01 00:00:00
abstract::We performed a retrospective study to determine the sensitivity of mammography in detecting breast cancer arising in women with augmented breasts. Of eight women with breast implants in whom breast cancer developed, six had mammograms before biopsy. Only two of the six cancers were identified mammographically (sensiti...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199101000-00013
更新日期:1991-01-01 00:00:00
abstract::It is difficult for some alcoholics to admit their illness and recognize their need for help. From experience a process called intervention has evolved. Basically it consists of a well planned and rehearsed scenario, devoid of coercion and criticism, in which the alcoholic can find no acceptable alternative to treatme...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198511000-00016
更新日期:1985-11-01 00:00:00
abstract::Transient synovitis of the hip is an acute and self-limited disease commonly seen in children. It is the most common cause of acute hip pain in children ages 3 to 10. It is not considered a disease of adults. It usually only affects one hip. The child may complain of pain that is much worse with walking and may actual...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000199746.29009.4c
更新日期:2006-02-01 00:00:00
abstract::We report a case of perforated solitary jejunal diverticulum in an 80-year-old woman. Jejunal diverticulosis occurs in 0.07% to 2.0% of the population. Jejunal diverticulitis with perforation is rare and is associated with high mortality. Treatment is surgical resection of the involved segment. Several theories to exp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199505000-00013
更新日期:1995-05-01 00:00:00