The effect of monomer-to-powder ratio on the material properties of cranioplastic.

abstract：:Bone morphogenetic proteins (BMPs) are known to induce new bone formation in vivo but treating trabecular bone defects with a BMP based therapeutic remains controversial. Here, we evaluated the safety and efficacy of a novel Autologous Bone Graft Substitute (ABGS) comprised of recombinant human BMP6 (rhBMP6) dispersed...

journal_title：Bone

authors： Durdevic D,Vlahovic T,Pehar S,Miklic D,Oppermann H,Bordukalo-Niksic T,Gavrankapetanovic I,Jamakosmanovic M,Milosevic M,Martinovic S,Sampath TK,Peric M,Grgurevic L,Vukicevic S

更新日期：2020-11-01 00:00:00

abstract：:Peroxisome proliferator activated receptors (PPARs) are DNA-binding nuclear hormone receptors that are upregulated in response to high fat diets. PPARs are structurally related to the type II nuclear receptors, including the thyroid hormone receptors (TRs). To investigate if PPARs modulate TR-mediated terminal differe...

journal_title：Bone

authors： Wang L,Shao YY,Ballock RT

更新日期：2005-09-01 00:00:00

abstract：:The effects of imaging parameters and special configuration of objects within the reconstruction space on the micro computed tomography (μCT) based mineral density have been explored, and a series of density correction curves have been presented. A manufacturer-provided calibration phantom (0, 100, 200, 400, 800 mg HA...

journal_title：Bone

authors： Entezari V,Vartanians V,Zurakowski D,Patel N,Fajardo RJ,Müller R,Snyder BD,Nazarian A

更新日期：2012-03-01 00:00:00

abstract：:Inflammation is an important part of the fracture repair process which requires osteogenic cells to interact with innate immune cells such as macrophages. All murine macrophages express the F4/80 cell surface marker but they may be further subdivided into two main phenotypes: M1 (proinflammatory) or M2 (anti-inflammat...

journal_title：Bone

authors： Hozain S,Cottrell J

更新日期：2020-09-01 00:00:00

abstract：:Vitamin K may be important in bone metabolism. Notably, high-dose menaquinone-4 (menatetrenone, MK4) has been reported to reduce ovariectomy (ovx)-induced bone loss in rats and to decrease osteoporotic fracture in postmenopausal women. However, it is unclear whether these beneficial effects reflect a physiologic effec...

journal_title：Bone

authors： Binkley N,Krueger D,Engelke J,Crenshaw T,Suttie J

更新日期：2002-06-01 00:00:00

abstract：:The use of combined antiretroviral agents during pregnancy is important to prevent mother-to-child transmission of human immunodeficiency virus (HIV). Antiretroviral treatment (ARV) is associated with reduced bone mass and altered bone metabolism in HIV-infected patients. There are no data regarding the effect of ARV ...

journal_title：Bone

authors： Mora S,Giacomet V,Viganò A,Cafarelli L,Stucchi S,Pivetti V,Manfredini V,Puzzovio M,Zuccotti G

更新日期：2012-01-01 00:00:00

abstract：:Juvenile osteoporosis (JO) is characterized by bone fragility during development, low bone mass and absence of extraskeletal features. Heterozygous loss-of-function mutations in LRP5 have been found in a few patients, but bone tissue and bone material abnormalities associated with such mutations have not been determin...

journal_title：Bone

authors： Fahiminiya S,Majewski J,Roughley P,Roschger P,Klaushofer K,Rauch F

更新日期：2013-11-01 00:00:00

abstract：:Oestrogen deficiency-related bone loss in the ovariectomized (OVX) mouse is a common model for osteoporosis. However, a comprehensive in vivo assessment of intervention-related changes in multiple bone properties, and in multiple mouse strains, is required in order to identify an appropriate model for future evaluatio...

journal_title：Bone

authors： Roberts BC,Giorgi M,Oliviero S,Wang N,Boudiffa M,Dall'Ara E

更新日期：2019-10-01 00:00:00

abstract：:Bisphosphonates (BP), especially alendronate and risedronate, are the drugs most commonly used for osteoporosis treatment, being incorporated into the skeleton where they inhibit bone resorption and are thereafter slowly released during bone turnover. However, there are few data on the release of BP in patients who ha...

journal_title：Bone

authors： Peris P,Torra M,Olivares V,Reyes R,Monegal A,Martínez-Ferrer A,Guañabens N

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Rheumatoid arthritis (RA) is accompanied by potential risk of bone mineral loss. In this study, we developed a screening index for the osteoporosis related level of bone mineral density loss for RA patients as a substitute to the dual-energy X-ray absorptiometry (DXA) method. METHODS:X-ray pictures of both s...

journal_title：Bone

authors： Yoshii I,Akita K

更新日期：2020-08-01 00:00:00

abstract：:Alagille syndrome (ALGS) is an autosomal dominant disorder attributed to mutations in the Notch signaling pathway. Children with ALGS are at increased risk for fragility fracture of unknown etiology. Our objective was to characterize bone mass, geometry, and microarchitecture in children with ALGS. This was a cross-se...

journal_title：Bone

authors： Kindler JM,Mitchell EL,Piccoli DA,Grimberg A,Leonard MB,Loomes KM,Zemel BS

更新日期：2020-12-01 00:00:00

abstract：:Inhaled corticosteroids are the cornerstone of the modern therapy for asthma. In recent years, inhaled corticosteroids have been used in higher doses than previously. This has caused concern about possible osteoporotic side-effects. We studied bone mineral densities (BMDs) in 19 non-smoking women (mean age 53 years, r...

journal_title：Bone

authors： Herrala J,Puolijoki H,Impivaara O,Liippo K,Tala E,Nieminen MM

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Evidence of the effect of vitamin K on bone health is conflicting. The aim was to investigate the association between intake of vitamins K1 and K2 and subsequent risk of hip fracture in a general population sample, as well as potential effect modification by apolipoprotein E gene (APOE) status by presence of...

journal_title：Bone

authors： Apalset EM,Gjesdal CG,Eide GE,Tell GS

更新日期：2011-11-01 00:00:00

abstract：:Controversial results were reported on the association of vitamin D receptor (VDR) polymorphisms and bone mineral density (BMD). We studied allelic frequencies of the BsmI, ApaI, and TaqI restriction fragment length polymorphisms (RFLPs) in 144 normal healthy southern Chinese premenopausal women aged between 30 and 40...

journal_title：Bone

authors： Kung AW,Yeung SS,Lau KS

更新日期：1998-04-01 00:00:00

abstract：:CCN2/connective tissue growth factor (CCN2/CTGF) is known to promote both the proliferation and differentiation of chondrocytes, which actions are mediated by ERK and p38 MAPK, respectively. In this study, we first re-evaluated the involvement of multiple MAPKs therein and found that JNK also mediated such CCN2 signal...

journal_title：Bone

authors： Yosimichi G,Kubota S,Nishida T,Kondo S,Yanagita T,Nakao K,Takano-Yamamoto T,Takigawa M

更新日期：2006-06-01 00:00:00

abstract：:GM1 gangliosidosis is a lysosomal storage disorder caused by mutations in GLB1 encoding a lysosomal β-galactosidase. This disease is a continuum from the severe infantile form with rapid neurological decline to the chronic adult form, which is not life-limiting. The intermediate or type 2 form can be further classifie...

journal_title：Bone

authors： Ferreira CR,Regier DS,Yoon R,Pan KS,Johnston JM,Yang S,Spranger JW,Tifft CJ

更新日期：2020-02-01 00:00:00

abstract：:Previous work with cultured primary cells, from our group and from other laboratories, has shown that signals from extracellular matrix, transduced by integrins, play critical roles in regulating gene expression, tissue-specific differentiation, and survival of primary osteoblasts and fibroblasts. This summary will fo...

journal_title：Bone

authors： Damsky CH

更新日期：1999-07-01 00:00:00

abstract：:The striking predilection of temporomandibular disorders (TMD) in women, especially during gonad-intact puberty or reproductive years, indicates that oestrogen plays an important role in the progression of TMD, but the underlying mechanism remains unclear. In this study, unilateral anterior crossbite (UAC) was used to...

journal_title：Bone

authors： Ye T,Sun D,Mu T,Chu Y,Miao H,Zhang M,Yang H,Liu Q,Lu L,Xing X,Yu S

更新日期：2018-06-01 00:00:00

abstract：:During the 40 years since its discovery, calcitonin (CT) has been regarded primarily as an inhibitor of bone resorption and its therapeutic applications have been based on this property. A significant body of literature also indicates additional anabolic effects in animal and in vitro models. In a variety of bone loss...

journal_title：Bone

authors： Wallach S,Rousseau G,Martin L,Azria M

更新日期：1999-11-01 00:00:00

abstract：:Numerous studies have investigated the effects of physical activity on bone health; however, little is known about the effects of isokinetic strength training on bone. While bone mineral density (BMD) is widely used to assess bone health and fracture risk, there are several limitations of this measure that warrant new...

journal_title：Bone

authors： Miller LE,Wootten DF,Nickols-Richardson SM,Ramp WK,Steele CR,Cotton JR,Carneal JP,Herbert WG

更新日期：2007-10-01 00:00:00

abstract：:A characteristic sign of zinc deficiency is retarded skeletal growth, but the role of zinc in osteoblasts is not well understood. Two major events for bone formation include osteoblast differentiation by bone marker gene expression, which is mainly regulated by bone-specific transcription factor Runx2 and extracellula...

journal_title：Bone

authors： Kwun IS,Cho YE,Lomeda RA,Shin HI,Choi JY,Kang YH,Beattie JH

更新日期：2010-03-01 00:00:00

abstract：:Osteoclasts (OCs) attach to the extracellular matrix via specialized attachment structures called podosomes, which form a prominent F-actin-rich ring that is thought to correspond to the sealing zone of resorbing OCs. Calcitonin (CT), a 32-amino acid polypeptide, inhibits bone resorption by decreasing motility, induci...

journal_title：Bone

authors： Shyu JF,Shih C,Tseng CY,Lin CH,Sun DT,Liu HT,Tsung HC,Chen TH,Lu RB

更新日期：2007-05-01 00:00:00

abstract：:Impact microindentation (IMI) is a Reference Point Indentation technique measuring tissue-level properties of cortical bone in humans in vivo. The nature, however, of the properties that can affect bone strength is incompletely understood. In the present study we examined bone material properties in transiliac bone bi...

journal_title：Bone

authors： Rokidi S,Bravenboer N,Gamsjaeger S,Misof B,Blouin S,Chavassieux P,Klaushofer K,Paschalis E,Papapoulos S,Appelman-Dijkstra N

更新日期：2020-02-01 00:00:00

abstract：:Fibroblast growth factor 23 (FGF23) circulates as active protein and inactive fragments. Low iron status increases FGF23 gene expression, and iron deficiency is common. We hypothesized that in healthy premenopausal women, serum iron influences C-terminal and intact FGF23 concentrations, and that iron and FGF23 associa...

journal_title：Bone

authors： Imel EA,Liu Z,McQueen AK,Acton D,Acton A,Padgett LR,Peacock M,Econs MJ

更新日期：2016-05-01 00:00:00

abstract：:Fractal analysis is a method for describing complex shapes, including the cancellous structure of bone. It describes the surface texture and form of individual trabecular profiles and the overall cancellous structure. Sixty-four postmenopausal women with symptoms of back pain were referred for investigation for osteop...

journal_title：Bone

authors： Fazzalari NL,Parkinson IH

更新日期：1998-07-01 00:00:00

abstract：:The incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are well known for their insulinotropic effects and they are thought to affect bone homeostasis as mediators in the so-called entero-osseous axis. We examined the contributions of endogenous GIP and GLP-1, resp...

journal_title：Bone

authors： Helsted MM,Gasbjerg LS,Lanng AR,Bergmann NC,Stensen S,Hartmann B,Christensen MB,Holst JJ,Vilsbøll T,Rosenkilde MM,Knop FK

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:There is evidence that the extent of vertebral bone marrow adiposity increases caudally along the vertebral column in children and adolescents. However, no studies have examined the lipid composition of bone marrow along the vertebral column, which may uniquely influence bone acquisition and metabolism durin...

journal_title：Bone

authors： Whitney DG,Devlin MJ,Alford AI,Caird MS

更新日期：2021-01-01 00:00:00

abstract：:Hypertension and osteoporosis are two major chronic diseases affecting the elderly. A cross-sectional study of 3887 Chinese men (n = 1958) and women (n = 1929) was used to explore the association between angiotensin converting enzyme inhibitor (ACEI) use and bone mineral density (BMD). The participants were aged 65 ye...

journal_title：Bone

authors： Lynn H,Kwok T,Wong SY,Woo J,Leung PC

更新日期：2006-04-01 00:00:00

abstract：:The traditional view of osteoporotic fractures is that they result from a reduction in bone mass combined with alterations in the micro-architecture. Apart from the effects of bone remodeling, the material properties of the remaining bone are thought to be unaffected. To test this, we compared the degree of matrix min...

journal_title：Bone

authors： Loveridge N,Power J,Reeve J,Boyde A

更新日期：2004-10-01 00:00:00

abstract：:The lung interfaces with atmospheric oxygen via a large surface area and is perfused by the entire venous return bearing waste products collected from the whole body. It is logical that the lung is endowed with generous anti-oxidative capacity derived both locally and from the circulation. The single-pass pleiotropic ...

journal_title：Bone

authors： Hsia CCW,Ravikumar P,Ye J

更新日期：2017-07-01 00:00:00