Abstract:
:Seventy four liver bioptic specimens of 66 patients with chronic hepatitis C were analyzed ultrastructurally and by light microscopy. According to histological activity of the disease, the patients were divided in groups with minimal activity (CPHa), mild activity (CPHb-CAHa), and moderate and severe activity (CAHb,c), respectively. The presence of lamelar, simple and complex lipid inclusions in the cytoplasm, as well as the presence of nuclear bodies and morphology of the nucleolus were analyzed by classic methods of transmission electron microscopy. Cytoplasmic lamelar inclusions were found in 84.6% of patients, and simple and complex lipid inclusions were noted in 85.1% of patients, without the differences related to histological and enzyme activity. Unaltered nucleolus was most frequently observed in patients with minimal disease activity (84.6%), viral changed in patients with mild activity (48.4%) and synthetic active in patients with moderate and severe activity (66%). Serum aminotransferase activity was significantly higher in patients with viral changed and synthetic active nucleolus. These results can indicate that HCV induces cytopathogenic and immunologic damage of hepatocytes. The presence of virus acts as toxic agent that damages hepathocytes' metabolism, thus resulting in occurrence of cytoplasmic lamelar, simple and complex lipid inclusions, respectively. Immunologic damages occur when the virus alters cell membrane of hepatocytes.
journal_name
Vojnosanit Pregljournal_title
Vojnosanitetski pregledauthors
Nózić D,Skaro-Milić A,Dimitrijević Jsubject
Has Abstractpub_date
1999-07-01 00:00:00pages
351-7issue
4eissn
0042-8450issn
2406-0720journal_volume
56pub_type
杂志文章abstract:INTRODUCTION:Otitic complications arise from expansion of the middle ear infection. Subdural empyema is a rare otitic complication, and both retropharyngeal and parapharyngeal abscesses have been described in just a few cases. CASE REPORT:A 30-year-old male was, admitted as an emergency case because of breathing diffi...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND/AIM:Anatomical parameters of the bony components of the hip joint are essential for better understanding of etiopathogenesis of diseases like primary osteoarthrosis of the hip joint. The aim of this reserch was to examine the normal acetabular morphometry in Serbian population and to determine whether there ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND/AIM:Retroperitoneal fibrosis (RPF) repre sents a chronic pathological process characterized by fibro sis which entraps and compresses the ureters and the grea blood vessels in the retroperitoneal space. A specific form of RPF is idiopathic RPF, an uncommon collagen vasculaj disease of unclear etiology. The s...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp140426076h
更新日期:2015-10-01 00:00:00
abstract::Epilepsy is chronic, multietiologic disease of the cerebrum, with different clinical features and with frequent occurrence of emotional and psychic disorders. In this report, we presented the case of female patient, 16 years old, examined in our Clinic twice. The diagnosis of epilepsy was established on the basis of t...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To evaluate how infection of extremity after war wound influenced the possibilities and immediate effects of a physical therapy. METHODS:The retrospective clinical investigation comparing two groups: group A (n = 86) with infection, group B (n = 87) without infection. Main indicators for possibilities of the...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::In the period from January 1st, 1969, to December 31st, 1988, 585 osteosyntheses of the closed bone fractures of lower limbs were performed at the Orthopedic department at the Military Hospital in Nis. At the same period 25 postoperative osteomyelitis were registered, i.e., 4.27%. The average duration of osteosynthesi...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::Stomach cancer mortality in the period 1975-1990 in Belgrade has been analysed. In a sixteen-year period the mean standardised stomach cancer mortality rate was 11.4 per 100,000 inhabitants (males-14.8%000: females-8.6%000). The specific mortality rate by age shows low values before age 34, then it comes to its sudden...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND/AIM:Lichen planus is a chronic, immunologic, mucocutaneous disease with a wide range of clinical manifestations. The aim of this retrospective study was to evaluate the most common forms of oral lichen planus (OLP) and its symptoms and to describe treatment responses in patients during 10-year period. METHO...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:Behcet's disease is multisystemic vasculitis which affects vein and artery blood vessels. Intestinal perforation rarely occurs as clinic manifestation in as little as 1% of patients. The transverse colon is the most infrequent site of perforation. We presented a patient diagnosed with Behcet's disease who ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1111992t
更新日期:2011-11-01 00:00:00
abstract::The investigation was performed on a sample of members of a special parachute unit, aged 25-30 years. During combat activities in the territory of former Yugoslavia, in the period of 1991-92, they were exposed to intensive stress and psychotraumatic events which could have detrimental influence on personality and psyc...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND/AIM:Environmental factors may influence the disease activity in patients with relapsing-remitting multiple sclerosis (MS). The aim of this study was to evaluate the in- fluence of air pollution and seasonal climate factors of any on number of relapses in MS patients during a consecutive 5 years of observatio...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp140121030v
更新日期:2015-01-01 00:00:00
abstract:Background/Aim:Increasing epidemiological studies suggest the association between psoriasis and metabolic syndrome. The aim of this study was to assess the association of metabolic syndrome and its components with psoriasis in a sample of patients from Montenegro, and to predict the factors that determine the metabolic...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/VSP150114138R
更新日期:2016-11-01 00:00:00
abstract::Carbon dioxide (CO2) influence in generation of active oxygen forms (AOF) in human mononuclear cells (blood phagocytes and alveolar macrophages) and animal cells (tissue phagocytes, parenchymal and interstitial cells of liver, kidney, lung, brain and stomach) was investigated. The AOF generation was examined by the me...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND/AIM:The cell line C6 is a continuous cell line of rat glioma and, as a transplantable line, is frequently used for induction into in vivo model of primary brain tumor. It is believed that, pursuant to its histological traits and biological behavior, this experimental tumor corresponds to human anaplastic ast...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2014-09-01 00:00:00
abstract::The aim of this case-control study, conducted in Serbia during the period 1998-2000, was to investigate whether diet was associated with the development of gastric cancer. The case group consisted of 131 patients with histologically confirmed gastric cancer, and the control group of 131 patients with orthopedics disea...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp0306697s
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:Dental injuries in immature permanent teeth often result in endodontic complications. Apexification technique using calcium hydroxide is associated with certain flaws, such as long treatment time, the possibility of tooth fracture and incomplete calcification. The use of an apical plug employing mineral tr...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1308781c
更新日期:2013-08-01 00:00:00
abstract::Esophageal stapler transection was performed in 15 patients with bleeding from the dilated esophageal veins in the period 1984-1988. In 7 patients operated on as urgent cases due to prolonged uncontrolled bleeding, the mortality was high--71.4%, contrary to the group of electively operated patients in whom the mortali...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Prostatic gland basal cell proliferations exhibit morphological continuum ranging from basal cell hyperplasia to basal cell carcinoma. In the following report, we described clinical features, morphological spectrum, neuroendocrine differentiation and histogenesis of prostatic gland basal cell carcinoma in ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1106515g
更新日期:2011-06-01 00:00:00
abstract::During the last twenty-year period therapeutic plasma exchange (TPE) was used in the treatment of 68 patients with myasthenia gravis and 61 patients with multiple sclerosis. The therapeutic effects were evaluated on the basis of neurologic deficit changes, electrophysiological findings, necessary laboratory analyses a...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND/AIM:Reperfusion of previously ischemic tissue leads to injuries mediated by reactive oxygen species. The aim of the study was to investigate the effects of different anesthesia techniques on oxidative stress caused by tourniquet-induced ischemia-reperfusion (IR) injury during extremity operations at children...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章,随机对照试验
doi:10.2298/vsp1008659b
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND/AIM:Gunshot wounds caused by the automatic rifle M70AB2 (AK-47) 7.62 mm, after the primary surgical management, were closed with delayed primary suture during the next four to seven days. This period coincides with the fibroblastic phase of wound healing. Fibrin glue is used as a local hemostatic and as a ma...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp131106050d
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION:The number of humans infected by Fasciola hepatica is increasing worldwide. Humans can become accidental hosts by ingesting drinking water or plants contaminated with metacercariae. CASE REPORT:We reported a case of a 68-year-old Serbian woman, in which the diagnosis of acute fasciolosis had been establis...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1402202p
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND/AIM:Tibial perfusion in diabetic microangiopathy is considered to be a diagnostic problem. A special place in quantifying muscle microcirculatory perfusion belongs to thallium 201 muscle perfusion scintigraphy (201T1 PS). Thallium, showing the characteristics of potassium (K+), enters a cell by means of acti...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1102161c
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND/AIM:In modern training technology, assessment of aerobic bioenergetic potential in athletes is commonly performed by standard laboratory procedures to determine basic or specific functional abilities for specific sport activity or discipline. The aim of study was to assess the aerobic bioenergetic potential ...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp110208043m
更新日期:2013-07-01 00:00:00
abstract::Fahr's syndrome is a rare clinical entity consisting of certain metabolic, biochemical, neuroradiologic and neuropsychologic phenomena in which extrapyramidal phenomenology clinically dominates. In this report, primarily from educational reasons, we have presented a female patient, who was before admittance to our cli...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract:INTRODUCTION:Myxomas arising from the right ventricle are extremely rare. CASE REPORT:We presented a 71-year-old patient with worsening symptoms of the exertional dyspnea and atypical chest pains lasting 6 months. A transthoracic and transesophageal echocardiogram revealed a large, 2.6 x 2.2 cm, ovoid, well-circumscri...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1306609o
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND/AIM:Acute low back pain (ALBP) is one of the most frequent painful conditions in the human population. The objective of the paper was to compare the efficacy of the low power laser (LPL) in the pain and the muscular spasm reduction with conservative methods of physical medicine. METHOD:The prospective cohor...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp1101057m
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/AIM:Urinary tract infections are still the most frequent complications in patients with spinal cord injury (SCI). The aim of this study was to analyze the factors influencing development of urinary tract infections during rehabilitation in patients with SCI. METHODS:This retrospective case/control study inc...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:10.2298/vsp140725116s
更新日期:2015-12-01 00:00:00
abstract::In order to detect biochemical parameters in the peripheral blood which would serve as an indicator of severity of blast injuries, the enzyme dynamics (creatine kinase, aspartat transaminase, alanin transaminase, lactic dehydrogenase, alkaline phosphatase, angiotensin convertase) has been followed up in the serum of s...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::The frequency of alcohol abuse in the soldiers of Herzegovinian corps of the Republic of Srpska Army during the 1992-1994 war, who took part in combat action was investigated by retrospective analysis of medical documentation. The same procedure was performed in the members of Yugoslav Army for the same period who did...
journal_title:Vojnosanitetski pregled
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00