Disease relapses in multiple sclerosis can be influenced by air pollution and climate seasonal conditions.

Abstract:

BACKGROUND/AIM:Environmental factors may influence the disease activity in patients with relapsing-remitting multiple sclerosis (MS). The aim of this study was to evaluate the in- fluence of air pollution and seasonal climate factors of any on number of relapses in MS patients during a consecutive 5 years of observation. METHODS:We retrospectively analyzed data of MS patients from the town of Niš, hospitalized at the Clinic of Neurology, Clinical Center Niš, Serbia, from 2005 to 2009. Climate data: mean daily sun shining; mean monthly sun shining, mean whole daily cloudiness, daily cloudiness at 7 a.m, 2 p.m. and 9 p.m. and air pollution expressed by NSR (New Source Review) were obtained from the Meteorology Observatory Niš. RESULTS:During a 5-year of observation there were 260 relapses in 101 MS patients. The number of relapses showed a significantly negative correlation with the number of days with NSR < 2 (p = -0.31; p < 0.01) and a positive correlation with the mean whole daily cloudiness (p < 0.05), mean daily cloudiness at 7 a.m. (p < 0.05) and 2 p.m. (p < 0.01). We found a significantlly positive correlation (p < 0.05) between the reduced number of relapses during the period of high vitamin D season, i.e. July-October. There was a statistically significant increase (p < 0.01) of the number of relapses during spring (x = 6.53; SD = 3.98) compared to the other three seasons. The joint presence of lower number of days with NSR < 2 during low vitamin D season (January- April) correlated with a statistically significant increase of the number of relapses in MS patients (F = 5.06, p < 0.01). CON- CLUSION: The obtained results confirmed the influence of air pollution and climate seasonal conditions on disease relapses in MS patients based on a long-term observation. Lower numbers of days with low air pollution during the periods with low vitamin D (January-April), especially with increased cloudiness at 2 p.m, induce a higher risk of MS relapses in southern continental parts of Europe.

journal_name

Vojnosanit Pregl

journal_title

Vojnosanitetski pregled

authors

Vojinović S,Savić D,Lukić S,Savić L,Vojinović J

doi

10.2298/vsp140121030v

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

44-9

issue

1

eissn

0042-8450

issn

2406-0720

journal_volume

72

pub_type

杂志文章
  • [Value of urinary cytology findings in the diagnosis of acute renal graft rejection].

    abstract:BACKGROUND:Acute rejection of allograft is one of the most serious complications of renal transplantation that requires fast and precise diagnostic approach. In this paper our experience in cytologic urinalysis as a diagnostic method of the acute renal allograft rejection was reviewed. METHODS:The study group included...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0301035t

    authors: Tatomirović Z,Bokun R,Dimitrijević J,Ignjatović L,Aleksić A,Hrvacević R

    更新日期:2003-01-01 00:00:00

  • Asymptomatic flow of Rosai-Dorfman disease.

    abstract:INTRODUCTION:Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character of the disease, often presents a diagnostic dilemma requiring immunohistochemical staining of surgically removed tumor to confirm ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1408780p

    authors: Petrović D,Mihailović D,Petrović S,Zivković N,Mijović Z,Bjelaković B,Kostić M,Kesić L,Stanković A,Petrović M,Vucković I

    更新日期:2014-08-01 00:00:00

  • Rapunzel syndrome.

    abstract:INTRODUCTION:Trichobezoars are foreign bodies in gastrointestinal tract, composed of hair. They occur mainly in children and adolescents suffering from trichotillophagia. They commonly occur in the stomach, but as they enlarge over time, they can extend through the pylorus into distal parts of the small intestine resem...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Petrović G,Nagorni A,Bjelaković G,Stojanov DB,Dinić BR,Brzacki V

    更新日期:2012-08-01 00:00:00

  • [Lateral humeral epicondylitis].

    abstract::Incidence of the epicondylitis humeri lateralis in a sample of 48 patients was analyzed according to age groups. The highest incidence was found in the age group of 21-30 that corresponds to the etiologic factor of more intensive work with extended arm and clenched hand, practiced by tennis players, bricklayers, house...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Ivanovski A

    更新日期:1994-03-01 00:00:00

  • Unusual metastasis of esophageal cancer.

    abstract:INTRODUCTION:Carcinoma of the esophagus is in the eighth place by the frequency of malignant diseases and the sixth cause of death from cancer worldwide. It usually metastasizes to regional lymph nodes, liver, lungs, central nervous system, and bones, but metastases can appear to unusual locations such as facial skin a...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Vidović V,Nikolić I,Vukojević J,Samardžija G,Kukić B,Bogdanović B,Petrović N

    更新日期:2014-10-01 00:00:00

  • [Dual chamber pacemaker in the treatment of paroxysmal atrial fibrillation].

    abstract:BACKGROUND:Atrial fibrillation is the most frequent cardiac dysrhythmia. The aim of this study was to show the role and the efficacy of a dual chamber pacemaker with the algorithm of atrial dynamic overdrive, in the suppression of paroxysmal atrial fibrillation. CASE REPORT:A woman with a classical bradycardia-tachyca...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0504329r

    authors: Raden G,Rafajlovski S,Perisic Z,Romanovic R

    更新日期:2005-04-01 00:00:00

  • [Oxidative status evaluation in elite karate athletes during training process].

    abstract:BACKGROUND/AIM:Oxidative stress is a state of disturbed balance between reactive oxygen species (ROS) and reactive nitrogen species (RNS) on the one hand, and antioxidative defense on the other. As a result of oxidative stress we have irreversible changes in cell function leading to pathological tissue changes, develop...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0907551p

    authors: Pesić S,Jakovljević V,Cubrilo D,Zivković V,Jorga V,Mujović V,Stojimirović B

    更新日期:2009-07-01 00:00:00

  • [Rapid simultaneous determination of organophosphorus pesticides in human serum and urine by liquid chromatography-mass spectrometry].

    abstract:BACKGROUND/AIM:Analysis of organophosphosphorus compounds and their metabolites in a biological material includes the use of numerous methods, covering both preparation of samples for analysis and their identification that is considered to be very complex. Low concentrations monitoring requires implementation of highly...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1009717z

    authors: Zlatković M,Jovanović M,Djordjević D,Vucinić S

    更新日期:2010-09-01 00:00:00

  • Estimation of chronic hepatitis C activity based on ultrastructural changes of hepatocytes.

    abstract::Seventy four liver bioptic specimens of 66 patients with chronic hepatitis C were analyzed ultrastructurally and by light microscopy. According to histological activity of the disease, the patients were divided in groups with minimal activity (CPHa), mild activity (CPHb-CAHa), and moderate and severe activity (CAHb,c)...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Nózić D,Skaro-Milić A,Dimitrijević J

    更新日期:1999-07-01 00:00:00

  • The effects of short-term preoperative physical therapy and education on early functional recovery of patients younger than 70 undergoing total hip arthroplasty.

    abstract:BACKGROUND/AIM:Hip arthroplasty is a routine operation which relieves pain in patients with osteoarthritis. The role of physical therapy after hip arthroplasty was recognized, but the importance of preoperative physical therapy and education is still to be judged. The aim of this paper was to investigate the effect of ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章,随机对照试验

    doi:10.2298/vsp0804291v

    authors: Vukomanović A,Popović Z,Durović A,Krstić L

    更新日期:2008-04-01 00:00:00

  • [Assesment of lower extremities ischemic disease by thallium 201 perfusion scintigraphy in patients with diabetic angiopathy].

    abstract:BACKGROUND/AIM:Tibial perfusion in diabetic microangiopathy is considered to be a diagnostic problem. A special place in quantifying muscle microcirculatory perfusion belongs to thallium 201 muscle perfusion scintigraphy (201T1 PS). Thallium, showing the characteristics of potassium (K+), enters a cell by means of acti...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1102161c

    authors: Cizmić M,Pucar D,Zoranović U

    更新日期:2011-02-01 00:00:00

  • [Hormonal status in patients with advanced prostatic cancer on the therapy with androgen blockade].

    abstract:BACKGROUND/AIM:Hormone suppression therapy is used in men with advanced prostate cancer improving chances of longer survival. The aim of this study was to investigate the influence of androgen blockades on testosterone and luteinizing hormone (LH) values in patients with locally advanced and metastatic prostatic cancer...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1104321v

    authors: Vojinov S,Levakov I,Jeremić D,Zivojinov S,Marusić G

    更新日期:2011-04-01 00:00:00

  • Index of lipid peroxidation and glucose utilization in the cerebrospinal fluid in patients with cerebral infarction.

    abstract::Cerebral ischemia could be observed as acute metabolic crisis, when oxygen and glucose supply is compromised and synthesis of energy is insufficient. Apart from the excitotoxicity, increased production of reactive oxygen species with consequent lipid peroxidation is also included in neuronal cell damage. Furthermore, ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Selaković V,Jovanović MD,Jovicić A,Mrsulja BJ,Malicević Z,Ninković M,Mihajlović R,Vasiljević I

    更新日期:2000-07-01 00:00:00

  • Multiple lateral sinus pericranii--A case report.

    abstract:INTRODUCTION:Sinus pericranii is a rare vascular anomaly. It is characterized by abnormal communication between the extracranial and intracranial venous system, usually involving the superior sagittal sinus and occasionally the transverse sinus. Off the midline lesions are extremely rare. Multiplicity, associated venou...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp140416065i

    authors: Ivetić D,Pavlićević G,Antić B,Kostić D

    更新日期:2015-09-01 00:00:00

  • Focal neuroendocrine differentiation in prostatic gland carcinoma with basaloid pattern.

    abstract:INTRODUCTION:Prostatic gland basal cell proliferations exhibit morphological continuum ranging from basal cell hyperplasia to basal cell carcinoma. In the following report, we described clinical features, morphological spectrum, neuroendocrine differentiation and histogenesis of prostatic gland basal cell carcinoma in ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1106515g

    authors: Gligorijević JV,Velicković LV,Jancić SA,Radovanović Z,Krstić MS,Katić VV

    更新日期:2011-06-01 00:00:00

  • [Dopa-responsive dystonia].

    abstract:BACKGROUND/AIM:Dystonia is considered to be a prolonged involuntary contractions of the muscles leading to twisting, repetitive movements or irregular postures. Etiologically, it could be classified as primary and secondary dystonia. Dopa-responsive dystonia (DRD) belongs to a group of primary dystonia. The aim of this...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0901029d

    authors: Durić G,Svetel M,Dzoljić E,Kostić V

    更新日期:2009-01-01 00:00:00

  • [Cytochemical and immunocytochemical characteristics of Meckel's diverticulum with heterotopic rests of pancreatic tissue].

    abstract:BACKGROUND:Meckel's diverticulum (MD) is a congenital anomaly of the small intestine. It results from incomplete obliteration and resorption of the proximal omphaloenteric duct connecting yolk sac with primitive gut in the fetal period. CASE REPORT:A case of 20-year old female with ectopic pancreatic rests in a MD was...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1012021p

    authors: Pavlović S,Janjić D,Mihajlović S,Stefanović N,Pavlović M,Stanojević G,Stojanović V

    更新日期:2010-12-01 00:00:00

  • [Effect of small doses of aspirin on thrombocyte aggregation].

    abstract::Aspirin (acetylsalicylic acid--ASA) inhibits pletlets thromboxane (TXA2) synthesis as well as endothelial prostacycline (PGI2) synthesis. Aiming to prevent PGI2 synthesis attempts have been made to reduce ASA doses. Here are presented results of ASA effects in daily dose of 100 mg given to 26 patients with mean age of...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Ciko Z,Mijić R,Tanasijević M

    更新日期:1991-05-01 00:00:00

  • Forensic-medical expertise of twenty four murdered citizens from Gospić and its surroundings.

    abstract::The forensic-medical expertise of 24 predominantly carbonized bodies, that were found at Kukin Do was reported. The victims were from Gospić and its surroundings, who disappeared between October 16-18, 1991. The expertise involved the identification of bodies, injury classification, determination of tools by which inj...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Stanković Z

    更新日期:1992-03-01 00:00:00

  • Experimental closure of gunshot wounds by fibrin glue with antibiotics in pigs.

    abstract:BACKGROUND/AIM:Gunshot wounds caused by the automatic rifle M70AB2 (AK-47) 7.62 mm, after the primary surgical management, were closed with delayed primary suture during the next four to seven days. This period coincides with the fibroblastic phase of wound healing. Fibrin glue is used as a local hemostatic and as a ma...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp131106050d

    authors: Djenić N,Višnjić M,Dragović S,Bojanić V,Bojanić Z,Djurdjević D,Djindjić B,Kostov M

    更新日期:2015-09-01 00:00:00

  • [Masked depression].

    abstract::The study comprised 25 patients with masked depression and 30 patients with endogenous depression. According to the general characteristics both groups were homogenous and accordingly, comparable. Together with clinical evaluation of depressive syndrome, psychological management was applied. Rorschach test, Thematic A...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Preradović M,Griva D,Eror S

    更新日期:1991-01-01 00:00:00

  • Diagnostic value of combined magnetic resonance imaging examination of brachial plexus and electrophysiological studies in multifocal motor neuropathy.

    abstract:BACKGROUND/AIM:Multifocal motor neuropathy (MMN) is an immune-mediated disorder characterised by slowly progressive asymetrical weakness of limbs without sensory loss. The objective of this study was to investigate the involvement of brachial plexus using combined cervical magnetic stimulation and magnetic resonance im...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1408723b

    authors: Basta I,Nikolić A,Apostolski S,Lavrnić S,Stosić-Opinćal T,Banjalić S,Knezević-Apostolski S,Ilić TV,Marjanović I,Milićev M,Lavrnić D

    更新日期:2014-08-01 00:00:00

  • Caregivers’ attitudes, knowledge and practices of oral care at nursing homes in Serbia.

    abstract:Background/Aim:Within the elderly population, residents in nursing homes, there is a greather risk of caries, periodontal disease and teeth loss. Assistance of caregivers in maintaininig good oral hygiene besides improving oral health can improve of residents general health and the qulity of their lives. The aim of thi...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/VSP141001065S

    authors: Stančić I,Petrović M,Popovac A,Vasović M,Despotović N

    更新日期:2016-07-01 00:00:00

  • 123I-FP-CIT brain SPECT (DaTSCAN) imaging in the diagnosis of patients with movement disorders--first results.

    abstract:BACKGROUND/AIM:123I-FP-CIT brain single-photon emission computed tomography (SPECT), DaTSCAN imaging, offers a possibility to study structural and biochemical integrity of presinaptic dopaminergic neurotransmitter system. The aim of this study was to evaluate the usefulness of 123I-FP-CIT brain SPECT scintigraphy in pa...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Jauković L,Ilić TV,Dopudja M,Ajdinović B

    更新日期:2012-02-01 00:00:00

  • [Sentinel lymph node biopsy in breast neoplasms].

    abstract:BACKGROUND/AIM:Sentinel node (SN) is the first draining node from the malignant tumor site. In the last decade, sentinel node biopsy (SNB) has been introduced as an alternative to axillary dissection in breast cancer. I n patients with negative SNB (sentinel node uninvolved with malignancy) axillary dissection is not r...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0903228v

    authors: Visnjić M,Kovacević P,Dordević G

    更新日期:2009-03-01 00:00:00

  • [Cerebellar hemangioblastomas--a study of the immunoprofile of neoplastic stromal component].

    abstract:BACKGROUND:Central nervous system hemangioblastomas (HBs) are uncommon, highly vascularized tumors that are predominantly found in the cerebellum. They occur sporadically or in association with von Hippel-Lindau (VHL) disease. HBs are of unknown histogenesis, and the origin of stromal cells is still a subject of debate...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0403273t

    authors: Tasić D,Dimov D,Kostov M,Ilić S,Dojcinov D,Jovanović M,Stanojević G,Dimov I

    更新日期:2004-05-01 00:00:00

  • Facial nerve injuries and its treatment.

    abstract::Twenty four patients with traumatic interruption of the conductivity of the facial nerve were treated in the period 1991-1996 at the Clinic for Maxillofacial Surgery. After topographic orientation about the site and level of the injury, the reconstruction of the nerve using nerve grafts was performed in all patients. ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Mirković Z,Jović N,Stosić S,Cvetinović M

    更新日期:1997-07-01 00:00:00

  • Liposarcoma of the paratesticular tissue and spermatic cord: a case report.

    abstract:INTRODUCTION:Liposarcomas are malignant tumors derived from fat tissues. Liposarcoma of the paratesticular tissue is rare. CASE REPORT:We presented a 51-year-old man with liposarcoma of paratesticular tissue and the spermatic cord, mimicking a testicular tumor. Ultrasound examination of this scrotal mass was hyperecho...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp1307695v

    authors: Vukmirović F,Zejnilović N,Ivović J

    更新日期:2013-07-01 00:00:00

  • [Percutaneous transluminal coronary angioplasty in the right ventricle myocardial infarction treatment].

    abstract:BACKGROUND/AIM:To present the results of percutaneous transluminal coronary angioplasty (PTCA) in the treatment of the patients with acute right ventricle myocardial infarction (ARVMI), with adjuvant analyses of the obtained results in the period of five years (2000-2004). METHODS:Thrombolytic therapy and the primary ...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:10.2298/vsp0510731r

    authors: Rafajlovski S,Orozović V,Ristić-Andelkov A,Raden G

    更新日期:2005-10-01 00:00:00

  • [Psychotraumatic reactions in participants and non-participants in warfare--members of a special unit].

    abstract::The investigation was performed on a sample of members of a special parachute unit, aged 25-30 years. During combat activities in the territory of former Yugoslavia, in the period of 1991-92, they were exposed to intensive stress and psychotraumatic events which could have detrimental influence on personality and psyc...

    journal_title:Vojnosanitetski pregled

    pub_type: 杂志文章

    doi:

    authors: Cabarkapa M,Mićović M,Spasojevic V

    更新日期:1994-09-01 00:00:00