[Cytochemical and immunocytochemical characteristics of Meckel's diverticulum with heterotopic rests of pancreatic tissue].

Abstract:

BACKGROUND:Meckel's diverticulum (MD) is a congenital anomaly of the small intestine. It results from incomplete obliteration and resorption of the proximal omphaloenteric duct connecting yolk sac with primitive gut in the fetal period. CASE REPORT:A case of 20-year old female with ectopic pancreatic rests in a MD was reported. She was hospitalized with clinical signs of acute appendicitis. During surgery an inflamated Meckel's diverticulum was found and a clinoid resection of the diverticulum was performed. Histologic examination revealed pancreatic tissue in the removed diverticulum. Endocrine cells (EC) were detected with Masson staining and aberrant pancreatic tissue with immunocytochemical LSAB2 method using pan cytokeratin as epithelial marker. CONCLUSION:Most of MD are asymptomatic and accessory finding during laparothomias for different causes, but complications of undiagnozed MD can be serious (diverticulitis, perforation with peritonitis or intestinal obstruction caused by invagination). In unclear cases, additional cytochemical and immunocytochemical diagnostics could be done.

journal_name

Vojnosanit Pregl

journal_title

Vojnosanitetski pregled

authors

Pavlović S,Janjić D,Mihajlović S,Stefanović N,Pavlović M,Stanojević G,Stojanović V

doi

10.2298/vsp1012021p

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1021-4

issue

12

eissn

0042-8450

issn

2406-0720

journal_volume

67

pub_type

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