Abstract：
BACKGROUND/AIM:In comparison to standard therapy autologous stem cell transplant (ASCT) with high doses mel-phalane has improved treatment of multiple myeloma (MM) patients. The aim of this study was to evaluate the results of treatment of MM patients in our center with ASCTconditioning with melphalane or combining busulphane, cyclophosphamide and melphalane. METHODS:We performed 62 ASCT procedures in 47 patients from 1998 till 2008. Single ASCT were performed in 32 patients (68%), after 3-6 cycles of (26% patients. RESULTS:Median engraftment was on 12th day. In a 50-month follow-up period 64% patients were alive. The overall response rate (ORR), wich was reached in 38 (80%) patients, was better in the group of patients treated in the early phase of MM. Totally 25 (53%) patients were without progression in a 25-month follow-up period. Twenty patients met criteria for CR + VGPR (very good partial remission), that was 5 patients more than in the period before ASCT. Fourteen (30%) patients died and median time till death was 17 months. CONCLUSION:The ASCT perfomed in early phase of MM after V A D induction had a significant influence onthe treatment of MM patients. Reaching CR + VGPR before and after the ASCT is predictive factor for overall survival (OS) or prolongation of period till recidive appears, progression, therapy withdrowal or death.
journal_name
Vojnosanit Pregljournal_title
Vojnosanitetski pregledauthors
Marjanović S,Stamatović D,Tukić L,Tarabar O,Elez M,Madjaru L,Balint B,Tatomirović Z,Kuljić-Kapulica N,Andjelković Ndoi
10.2298/vsp1105387msubject
Has Abstractpub_date
2011-05-01 00:00:00pages
387-92issue
5eissn
0042-8450issn
2406-0720journal_volume
68pub_type
杂志文章abstract：:The aim of this study was to investigate the influence of the corticosteroid therapy on the development and prognosis of proststreptococcal glomerulonephritis (PSGN) in the period of five years. The investigation included a group of 54 patients who were in the acute phase of poststreptococcal glomerulonephritis (PSGN)...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:Spleen embolization is a method of percutaneous occlusion of instrasplenic vascular network, by which is achieved a partial embolization of arterial branches with the convenience of controlled circulation reduction. Reduction achieved in this way corrects clinical and laboratory symptoms of hypersplenism and improves ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：INTRODUCTION:Metastatic renal cell carcinoma (RCC) frequently spreads not only to neighboring lymph nodes, but also to distant organs, including the lungs, liver, bones and brain. CASE REPORT:We presented three cases of RCC with colon metastasis. In the first, 63-year-old patient, after left nephrectomy followed with ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp120515014m
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND/AIM:Interaction between tumor cells and host's immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years. Myeloid-derived suppressor cells (MIDSCs) are heterogeneous population of immature dendritic cells, macrophages and gr...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp1504342s
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:Central nervous system hemangioblastomas (HBs) are uncommon, highly vascularized tumors that are predominantly found in the cerebellum. They occur sporadically or in association with von Hippel-Lindau (VHL) disease. HBs are of unknown histogenesis, and the origin of stromal cells is still a subject of debate...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0403273t
更新日期：2004-05-01 00:00:00
abstract：:The results obtained by the use of the smear method were analyzed in ex tempore diagnostics of 240 neurosurgical biopsies, done in the period from 1991 to 1993. Thirty three different pathologic lesions were found that had their special morphology on smears, indicating the high specificity of this method. In 226 cases...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：Background/Aim:The mechanism of impaired bone healing in diabetes mellitus includes different tissue and cellular level activities due to micro- and macrovascular changes. As a chronic metabolic disease with vascular complications, diabetes affects a process of bone regeneration as well. The therapeutic approach in bon...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/VSP151125013Z
更新日期：2016-12-01 00:00:00
abstract：:Twenty eight patients (18 men and 10 women) with delayed pressure induced urticaria were analyzed. The average age was 35.5 years, and the illness lasted 1-20 years, 4.07 years on average. The spontaneous cessation of illness came in 8 patients after approximately 5.75 years. In 23 patients there was also a classical ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND/AIM:Identification of patients with arterial hypertension and a possible onset of heart failure by determining the concentration of N-terminal pro-B-type natriuretic peptide (NT-proBNP) enables timely intensification of treatment and allows clinicians to prescribe and implement optimal and appropriate care. ...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp110322048p
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND/AIM:Basal cell carcinoma (BCC) is the most common form of skin cancer in the white population. Increasing incidence of BCC imposes the requirement to indentify the risk factors due to eventual preventive action. The aim of this study was to assess the role of some constitutional characteristics in developmen...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0706375r
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND/AIM:Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. The main physiopatological feature of MS is demyelination. Multiple sclerosis is one of three most common causes of severe disability in youngest people. In patients with MS, apart from complete psychophysical status and...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0908645k
更新日期：2009-08-01 00:00:00
abstract：:The aim of this study was to determine the resistance of Enterococcus faecalis (E. faecalis) and Enterococcus faecium (E. faecium) to penicillin, ampicillin, vancomycin, teicoplanin, gentamicin (high level), streptomycin (high level), oxytetracycline, chloramphenicol, rifampin, erythromycin, ciprofloxacin, norfloxacin...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0205499m
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND/AIM:123I-FP-CIT brain single-photon emission computed tomography (SPECT), DaTSCAN imaging, offers a possibility to study structural and biochemical integrity of presinaptic dopaminergic neurotransmitter system. The aim of this study was to evaluate the usefulness of 123I-FP-CIT brain SPECT scintigraphy in pa...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND/AIM:[corrected] Increased values of thyroid hormones in the clinical syndrome of hyperthyreosis affect blood pres sure values and its circadial variation. The aim of this study was to define the influence of hyperthyreosis on the values and circadial variations of arterial blood pressure, as well as to inves...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0802135i
更新日期：2008-02-01 00:00:00
abstract：:The controversy of data about the role of free radicals in the pathogenesis of bronchial asthma (BA) and lack of clear recommendations for the use of medicaments with antioxidant characteristics in the treatment of patients with BA has challenged us to undertake this study. The aim was to explain characteristics of ge...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND/AIM:Lichen planus is a chronic, immunologic, mucocutaneous disease with a wide range of clinical manifestations. The aim of this retrospective study was to evaluate the most common forms of oral lichen planus (OLP) and its symptoms and to describe treatment responses in patients during 10-year period. METHO...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND/AIM:Gunshot wounds caused by the automatic rifle M70AB2 (AK-47) 7.62 mm, after the primary surgical management, were closed with delayed primary suture during the next four to seven days. This period coincides with the fibroblastic phase of wound healing. Fibrin glue is used as a local hemostatic and as a ma...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp131106050d
更新日期：2015-09-01 00:00:00
abstract：:The aim of this case-control study, conducted in Serbia during the period 1998-2000, was to investigate whether diet was associated with the development of gastric cancer. The case group consisted of 131 patients with histologically confirmed gastric cancer, and the control group of 131 patients with orthopedics disea...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0306697s
更新日期：2003-11-01 00:00:00
abstract：:Nutritional status represents the satisfaction of the human body with nutritive and protective substances and is the reflection of these physical and physiological characteristics, bio-chemical composition, functional capability and the health status. The aim of the examinations and nutritional status monitoring was t...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：:The effect of gamaphos (0.6 mmol kg-1 im, 20 min before irradiation) was investigated upon the course and outcome of the surgical management of combined radiation-gunshot injury in pigs. The hypothesis was tested that the infliction of perforating gunshot injury (LD0/30 days) in pigs in the latent phase of the acute r...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：BACKGROUND:Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), is a synthetic compound increasingly popular as a recreational drug. Tablets known as ecstasy contain MDMA, but may also contain caffeine, ephedrine, paramethoxyamphetamine, 3,4-methylenedioxyamphetamine (MDA), amphetamine, methamphetamine, and ketamine. Aft...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0709635d
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND/AIM:The aim of this study was to apply computer-assisted methodology in assessment of Ki-67 positivity in "adenoma-like" dysplasia associated lesions or masses (DALMs), and carcinoma in ulcerative colitis (UC), and to determine a new approach to grading of Ki-67 staining intensity. METHODS:Immunohistochemic...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0711753z
更新日期：2007-11-01 00:00:00
abstract：INTRODUCTION:Epidemiological studies suggest that a high prevalence of alcohol addiction exists in female patients diagnosed with eating disorder in comparison to general population. For the purpose of explanation of the relationship of these disorders many conceptual models have been proposed. CASE REPORT:We presente...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp0703223v
更新日期：2007-03-01 00:00:00
abstract：:In the period from January 1st, 1969, to December 31st, 1988, 585 osteosyntheses of the closed bone fractures of lower limbs were performed at the Orthopedic department at the Military Hospital in Nis. At the same period 25 postoperative osteomyelitis were registered, i.e., 4.27%. The average duration of osteosynthesi...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：:Comparative clinical investigation was performed in 80 ASA I/II patients undergoing cataract surgery on one eye. Patients were randomly divided in to four groups, according to the method of anesthesia. Intraoperatively (T0-T6), decreasing of intraocular pressure (IOP) to the optimal values at the start of the operatio...
journal_title：Vojnosanitetski pregled
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND/AIM:Primary open-angle glaucoma is a multifactorial and progressive neuropathy, characterised by the acquired loss of ganglion cells of the retina and their axons. One of the risk factors for primary open-angle glaucoma is myopia over 5 diopters (D). The aim of our work was to investigate two groups of patie...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp111229024g
更新日期：2013-01-01 00:00:00
abstract：:Stomach cancer mortality in the period 1975-1990 in Belgrade has been analysed. In a sixteen-year period the mean standardised stomach cancer mortality rate was 11.4 per 100,000 inhabitants (males-14.8%000: females-8.6%000). The specific mortality rate by age shows low values before age 34, then it comes to its sudden...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：BACKGROUND/AIM:Proper nutrition and regular physical activity are essential parts of a adolescent's overall health. The aim of this research was to evaluated eating and physical activity behaviours and habits, nutritional and food knowledge, beliefs and self-efficacy related to diet and health of the adolescents of the...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：10.2298/vsp1306548d
更新日期：2013-06-01 00:00:00
abstract：:This paper deals with the experimental results of the effect of 1% dopamine on intraocular pressure, pupillary diameter and hemodynamic parameters after its local application in the rabbit eye. Our results show that locally applied dopamine caused an initial increase of intraocular pressure (IOP) (1 h), followed by it...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:Trichobezoars are foreign bodies in gastrointestinal tract, composed of hair. They occur mainly in children and adolescents suffering from trichotillophagia. They commonly occur in the stomach, but as they enlarge over time, they can extend through the pylorus into distal parts of the small intestine resem...
journal_title：Vojnosanitetski pregled
pub_type： 杂志文章
doi：
更新日期：2012-08-01 00:00:00
