[Neoplasm prevalence in renal transplantation].

Abstract:

OBJECTIVE:To analyze the prevalence of neoplasms in renal transplant patients and the relative risk for each tumor type according to the immunosuppression regimen. METHODS:609 renal transplants were reviewed. The risk index was determined by the ratio of the cases observed and predicted. RESULTS:Tumor prevalence was 4.9% (30/609); 6.3% (25/393) were males and 2.3% (5/216) were females. The most common tumors were cutaneous tumors other than melanoma, accounting for 2.4% (15/609), followed by Kaposi's sarcoma, pulmonary epidermoid carcinoma and genitourinary tumors (0.5%) and non-Hodgkin lymphoma (0.3%). Tumor prevalence was 6.8% for the group treated with azathioprine-prednisone and 3.9% for the cyclosporine A-prednisone-treated group. The estimated relative risk of having a neoplasm was 10-fold higher for the males and 4.2-fold higher for the females vs the general population. The mortality rate was 36.6%; specifically tumor-related in 82%. The mortality rate for those with solid tumors was 77.7%. The long-term survival rate for the group that developed a tumor was significantly lower than that of the general population, 75% vs 53%, respectively (p < 0.05). CONCLUSION:In this series no significant differences were observed relative to tumor prevalence or type according to the immunosuppression regimen. A recipient of a renal graft has a higher risk of developing a tumor. Cutaneous tumors were the most frequent. The long-term survival is lower for recipients of renal grafts who develop a tumor.

journal_name

Arch Esp Urol

authors

Gómez dos Santos V,Burgos Revilla FJ,Pascual Santos J,Orofino Ascunce L,Fernández-Juárez G,Crespo Martínez L,Clemente Ramos L,Carrera Puerta C,Marcen Letosa R,Escudero Barrilero A,Ortuño Mirete J

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

267-73; discussion 273-4

issue

3

eissn

0004-0614

issn

1576-8260

journal_volume

50

pub_type

杂志文章
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    doi:

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  • [Paratesticular leiomyosarcoma. Review and update].

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    pub_type: 杂志文章,评审

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  • [Scholia about the pandemia urbi et orbi et orbe generate by de COVID-19 disease.]

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    doi:

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  • [Usefulness of CAT in retroperitoneal fibrosis].

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    doi:

    authors: Zabala Egurrola JA,Arruza A,Pertusa C,Llarena R,Celio Marín J,Pérez-García A

    更新日期:1989-04-01 00:00:00

  • [Laparoscopic radical cystectomy and orthotopic urinary diversion in the male patient: technique].

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    pub_type: 杂志文章,评审

    doi:

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  • [Incomplete sagittal septum of the bladder].

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    doi:

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  • [Giant bladder hernia associated with bilateral incipient obstructive uropathy].

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  • Role and current situation of TURP in patients with elevated PSA.

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  • [Prognostic factors and radiosensitivity of bladder cancer].

    abstract::In the near future molecular biology will permit selection of patients with bladder cancer who can benefit more from radiotherapy and chemotherapy. There will also be an increase in the response rate due to the possibility of regulating the genes responsible for cellular radiosensitivity. ...

    journal_title:Archivos espanoles de urologia

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  • [Prostate-bladder rhabdomyosarcoma: therapeutic approaches].

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    pub_type: 杂志文章

    doi:

    authors: Vesga Molina F,Albisu Tristan A,Blasco de Villalonga M,Llarena Ibarguren R,Pertusa Peña C

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  • [Evaluation of the maturity of a Urology Department in terms of Quality. Management and Quality improvement operative objectives].

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    pub_type: 杂志文章

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    doi:

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    pub_type: 杂志文章,评审

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    doi:

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    doi:

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