Abstract：
OBJECTIVE:Serotonin and norepinephrine systems are involved in the neural control of lower urinary tract function. The aim of this study was to compare the response on striated anal sphincter electromyographic (SAS-EMG) activity and cystometric parameters, when duloxetine and clomipramine were intravenously administrated. METHODS:The effects of intravenous 1 and 2 mg./Kg. duloxetine or clomipramine on lower urinary tract function were studied in a total of 32 male and 32 female rabbits, under nonirritative conditions (intravesical infusion of saline) and in a model of bladder irritation (i.e., transvesical infusion of 0.5% acetic acid). A transurethral double-lumen catheter in male rabbits, and a subcutaneous cystostomy in female rabbits, were used for liquid infusion and recording of intravesical pressure during a cystometrogram. Simultaneously, SAS-EMG was recorded through electromyography electrodes placed in the perianal striated muscle. RESULTS:Cystometric parameters: Under irritative conditions, 2 mg./Kg. clomipramine in male rabbits and 1 or 2 mg./Kg. in female rabbits, depending on the dose, increased bladder capacity (BC), contraction duration (CD) and intercontraction interval (ICI), and decreased baseline pressure (BP). In male and female rabbits, duloxetine dose-dependently increased BC, CD and ICI. Under nonirritative conditions, clomipramine at 2 mg./Kg. and duloxetine dose-dependently solely increased BC in female rabbits. Electromyographic activity: A marked effect on SAS-EMG activity of duloxetine under irritative conditions was revealed in male and female rabbits. Under these conditions, clomipramine increased SAS-EMG activity only in female rabbits. Under nonirritative conditions, 2 mg./Kg. duloxetine increased SAS-EMG activity only in female rabbits. CONCLUSIONS:The stronger effects on the SAS-EMG activity were produced by duloxetine in female rabbits under irritated bladder conditions. Clomipramine, under irritative conditions, had a relaxing effect on intravesical pressure, which is not the case with duloxetine.
journal_name
Arch Esp Uroljournal_title
Archivos espanoles de urologiaauthors
Pérez Martínez FC,Vela Navarrete R,Castilla Reparaz Cdoi
10.4321/s0004-06142006000800019subject
Has Abstractpub_date
2006-10-01 00:00:00pages
839-48issue
8eissn
0004-0614issn
1576-8260journal_volume
59pub_type
杂志文章abstract：OBJECTIVES:The advances of minimally invasive surgery in urology over the last years have enabled a progressive and constant implementation of endourology and laparoscopy in pediatric patients. We perform a review of our experience, as a general hospital, with minimally invasive surgery performed in pediatric patients ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVES:To determine and compare the antioxidant power, cellular damage by lipidic peroxidation, and membrane damage in normal patients and patients with prostate cancer, so determining the antitumoral capacity. METHODS:The study population included 19 patients with elevated total PSA, greater than 4 ng/ml, with a ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142008000500001
更新日期：2008-06-01 00:00:00
abstract：:Holmium laser enucleation of the prostatic adenoma (HoLEP) represents an innovative surgical option for the treatment of bladder outlet obstruction caused by benign prostatic hypertrophy. The results of numerous randomized prospective studies and clinical case series have confirmed that HoLEP is a procedure that attai...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To report two rare cases of persistent müllerian duct syndrome. METHODS/RESULTS:Two patients with normal chromosome studies (46, XY) are presented. The radiological evaluation showed structures compatible with those of the müllerian duct. These structures were completely excised with excellent results. The h...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：:Four hundred and thirty-eight men with histologically confirmed prostatic adenocarcinoma were diagnosed consecutively and followed up closely for up to ten years. The mean age at presentation was 72.5 years and ranged from 45.3 to 91.0 years. Half of the total presented with symptoms of increasing urinary outflow obst...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1989-01-01 00:00:00
abstract：OBJECTIVES:The value of ultrasonography for the study of female urinary incontinence has been redefined over the last years. METHODS:We review the literature about the value of ultrasound in the workup of females with urinary incontinence, mainly transperineal ultrasound for the female stress urinary incontinence (SUI...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142006000400012
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVES:To present a series of four cases of Gartner cysts and their clinical presentation. A bibliographic review was performed. METHODS:The series consisted of 4 women, mean age 39, who complained of a bulge at the anterior vaginal wall, associated with a variety of urinary symptoms. RESULTS:Surgical removal was...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVES:To present one case of paratesticular leiomyosarcoma, a rare tumor which has been reported in 5 cases only in our country. To review the management of this type of tumor. METHODS:A 73-year-old male presenting with a 4 cm mass adjacent to the right testicle underwent excision of the mass, spermatic cord and ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVES:To assess the efficacy of antibiotic prophylaxis for prevention of urinary infections and renal parenchymal damage in children with primary vesicoureteral reflux (VUR). METHODS/RESULTS:A search based on MEDLINE and The Cochrane Library was performed selecting those clinical trials and meta-analysis which co...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000200018
更新日期：2008-03-01 00:00:00
abstract：:23 cases of flexible retrograde nephroscopy system for undiagnosed hematuria or filling defect are reviewed. The introduction was carried out by combining hydraulic dilation, rigid ureterorenoscopy and a working sheath. The indications were merely diagnostic (filling defects and/or haematuria). The success rate was ve...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：OBJECTIVE:Recently, intraoperative floppy-iris syndrome (IFIS) has been related to tamsulosin treatment. This review evaluates the epidemiological evidence of the association of tamsulosin with IFIS and the necessity of a prior ophthalmolo-gic examination in this group of patients. METHOD:Systematic review of the lite...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000800008
更新日期：2008-10-01 00:00:00
abstract：:El nuevo coronavirus tipo 2 (SARS-CoV-2)del síndrome respiratorio agudo grave y la enfermedadque produce, enfermedad por coronavirus2019 (COVID-19) fueron descritos por primera vezen la ciudad China de Wuhan en Diciembre de2019 (1). En Marzo de 2020, la dispersión mundialde este nuevo patógeno, condujo a la declaració...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:To report a case of infected urachal cyst, with special reference to the difficulty in making the diagnosis due to the low incidence of this condition. METHODS/RESULTS:The embryologic origin of the urachus, its anomalies, clinical features, diagnosis and treatment are discussed. CONCLUSION:A high index of s...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVE:Seminal vesicle cysts are rare diseases and frequently cause no symptoms. An acquired giant seminal vesicle cyst in a 73-year-old man is presented. Bladder outlet obstruction was the main complaint, mimicking that arising from the prostate. METHODS:Ultrasonography and computed tomography revealed a well-defi...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:Radical prostatectomy is an excellent salvage method for patients with prostatic cancer when radical radiotherapy or brachytherapy fail. To define local failure is not always reliable; nevertheless, performing a prostatic biopsy two years after treatment could reach an early diagnosis. Another accepted attitude is to...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Patients on anticoagulant therapy may develop urologic complications, the most common being hematuria. Other less common but more severe complications are spontaneous hemorrhage arising from urological structures, as spontaneous perirenal hematoma, or from extra-urological structures, such as the iliac psoas muscle or...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-01 00:00:00
abstract：:Erectile dysfunction is not the only cause of impotence in the male; impotencia coeundi may result from various disorders, although cavernosal erectile function is normal. The present study reviews the congenital and acquired penile disorders, as well as the cutaneous disorders that may cause penile morphological chan...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:The recto-vesical fistula (FRV) that follows a radical prostatectomy is an unusual complication and involves a difficult management. A wide variety of surgical aggressive repair techniques are described in literature, including end-colostomy. Furthermore, non-invasive procedures are barely documented. We pres...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2020-11-01 00:00:00
abstract：:Prostate Cancer (PCa) remains an exception among solid cancers since organ-sparing procedures are not considered as a standard option. Despite most men harbour low to intermediate risk disease at diagnosis, the vast majority are advised towards radical treatment. We performed a literature review to highlight and discu...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2016-07-01 00:00:00
abstract：:In the near future molecular biology will permit selection of patients with bladder cancer who can benefit more from radiotherapy and chemotherapy. There will also be an increase in the response rate due to the possibility of regulating the genes responsible for cellular radiosensitivity. ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：OBJECTIVES:Currently there are instruments to evaluate the different features of the impact on quality of life in those patients with prostate cancer undergoing any type of treatment, but most of them have 50 or more questions and they are difficult to apply in clinical practice. An English validation of a shortened ve...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVES:The objective of this article is to show the current situation regarding two surgical techniques for the treatment of renal lithiasis, RIRS (Retrograde intrarenal surgery) and PCNL (Percutaneous nephrolithotomy), specially concerning the larger size stones. We perform a literature review on the topic and add...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2017-01-01 00:00:00
abstract：:There is currently no existing methodology for evaluating normal exocrine function in the healthy rat. Consequently, most of the experimental studies that have been conducted are incomplete. For this reason, we developed an experimental model to investigate the testicular exocrine function using spermatozoa obtained f...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVES:To present a new case of adenomatoid tumor of the epididymis, the first report in our hospital since 1962. METHODS:We report a clinical case with a brief bibliographic review about adenomatoid tumor of the epididymis. The diagnostic and therapeutic implications are discussed focusing on the role of ultrasou...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142009000800009
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:To report our experience with the management of arterial priapism by embolization. METHODS:Two patients with arterial priapism secondary to perineal trauma are described. Diagnostic evaluation included intracorporal blood gas, echo Doppler and selective pudendal arteriographic assessment. Treatment was by se...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:Renal adenocarcinoma can present with a wide range of symptoms and clinical signs and among them pain is the more frequent. As a matter of fact, it can also assume the features of a reno-ureteral colic. This kind of symptom, however, is more frequently combined with macro-hematuria and seldom presents alone, even in t...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1990-09-01 00:00:00
abstract：:Endometriosis is relatively frequent in females of menstrual age and consists in the appearance of active endometrial tissue at sites other than the uterine cavity (genital system or adjacent organs). Endometrial tissue has been described to colonize the urinary system, particularly the urinary bladder. The most commo...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:Robotic radical prostatectomy is fast getting popular as an alternative to the open and laparoscopic radical prostatectomy. Planning for port placement and the assistant's role are the two crucial yardsticks for the success of this procedure. Ideal port placement for radical robotic prostatectomy is not only crucial f...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142007000400008
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:We report one case of gonadal stromal testicular tumor and perform a bibliographic review. METHODS/RESULTS:We present the case of a 42 year-old male patient consulting for a painless right testicular mass. Orchiectomy was performed and the patient underwent follow-up. CONCLUSIONS:Nonspecific sexual cord tum...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000700011
更新日期：2008-09-01 00:00:00
abstract：:Although the laparoscopic ureteral reimplantation (LUR) has a history of over 20 years, its presence in the literature is relatively sparse, almost always in the form of small case series with low statistical power, which has prevented consistent results. It has proven to be a safe and effective technique, improving t...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2017-05-01 00:00:00
