Abstract：
OBJECTIVE:To assess the efficacy of 60 MU intravesical alpha-2b interferon (IFN) in preventing recurrence of transitional cell carcinoma of the bladder. METHODS:A prospective, randomized double-blind study was conducted to assess the efficacy of 60 MU intravesical alpha-2b IFN compared to a control group. T1G2-G3 and the G1 recurrent tumors were included in the study (30 in each group). Instillation was started 2-3 weeks after complete TUR and administered once weekly for 12 weeks and once monthly thereafter for one year. RESULTS:The distribution according to sex and age of the patient, tumor size, grade and classification as primary or secondary was the same for both groups. Multiple tumors were prevalent in the IFN-treated group. During the first year of follow up, the tumor recurrence rate was 23.3% for the IFN-treated group and 36.6% for the control group. At 22.4 months mean follow up, the rate of recurrence was 40% for the IFN-treated group and 46.6% for the control group. Of these recurrences, 8.3% of tumors in the IFN group showed progression in grade and/or stage versus 35.7% for the control group. The disease-free interval averaged 8.5 months; 10.5 for the treated group and 6.9 months for the control group. Local or systemic toxicity was negligible. CONCLUSIONS:Alpha-2b IFN is well-tolerated at a dose of 60 MU. It prolongs the disease-free interval and while throughout the follow up period the recurrence rate is similar to that of the control group, it does seem to markedly slow progression in the grade and/or stage of the tumor.
journal_name
Arch Esp Uroljournal_title
Archivos espanoles de urologiaauthors
Portillo Martín JA,Martín García B,Hernández Rodríguez R,Correas Gómez MA,Gutiérrez Baños JL,del Valle Schaan JI,Monge Mirallas JM,Roca Edreira Asubject
Has Abstractpub_date
1995-06-01 00:00:00pages
479-88issue
5eissn
0004-0614issn
1576-8260journal_volume
48pub_type
临床试验,杂志文章,随机对照试验,评审abstract：:The present study was conducted to determine the reversibility of the seminal alterations following experimental unilateral cryptorchidism in relation to the time orchiopexy is performed. Two groups of 45 Wistar rats were subjected to mechanical unilateral cryptorchidism followed by prepubertal, early and late orchiop...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：OBJECTIVES:To describe a method to obtain images of open surgery at the lowest possible cost. The images provide useful information for patient records and teaching. METHODS:We have utilized a submersible endoscopic camera with no special features, close up lenses or automatic focussing device and a color printer. RE...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVES:To review the pathological criteria used to select patients for active surveillance, the optimization of biopsies and the role of confirmatory biopsy and of the transperineal approach. METHODS:A bibliographic revision of the last years about active surveillance in prostate cancer as well as prostate biopsy,...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVES:To assess the feasibility and a validity of the Spanish version of the FACT-P and its relation to urinary symptoms. METHODS:The Spanish version of the FACT-P was self-administered to 60 Prostate Cancer patients (pts) waiting to undergo radical treatment and 20 age-matched controls (con) with a negative biop...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVES:To study patient satisfaction and complications appeared in a series of patients with erectile dysfunction undergoing implant of penile prosthesis. METHODS:Retrospective study of all patients undergoing surgical treatment for erectile dysfunction by penile prosthesis implant between 1993 and 2003. Collected...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142005000900009
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:Benign tumors account for less than 1% of testicular tumors and the incidence is even lower in children. A rare case of epidermoid cyst of the testis in a child is described. The differential diagnosis and treatment options are discussed. METHODS/RESULTS:A case of unilateral epidermoid cyst of the testis in ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:Urinary unidiversion permits the possibility of enhancing the quality of life and probably the survivorship of previously diverted patients. A modification of this technique is described which utilizes Brickne's loop and a segment of the sigmoid to create a low pressure bladder, thus sparing more intestine. The good r...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：OBJECTIVE:To report a case of infected urachal cyst, with special reference to the difficulty in making the diagnosis due to the low incidence of this condition. METHODS/RESULTS:The embryologic origin of the urachus, its anomalies, clinical features, diagnosis and treatment are discussed. CONCLUSION:A high index of s...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVES:To report one case of primary adenocarcinoma of the seminal vesicles. METHODS/RESULTS:We report the case of a 69-year-old man with obstructive voiding symptoms. Digital rectal examination reveals a marked enlargement of posterior area of the prostate and surrounding tissues. Transrectal needle biopsy shows ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142009000800013
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVES:Testicular cancer affects young and fertile patients. Half of them are non seminomatous tumors. The management of this cancer in stage I includes: watchful waiting, chemotherapy and retroperitoneal lymph node dissection (RPLND). In the past, classic RPLND produced a high rate of anejaculation with the subseq...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：10.4321/s0004-06142008000400008
更新日期：2008-05-01 00:00:00
abstract：:Stone formation in the double J ureteral catheter is an uncommon complication that generally appears in patients that are predisposed to stone formation and persistent infection of the urinary tract. We report on a 29-year-old female patient in whom stone formation was observed in both ends of the catheter, less than ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Holmium laser enucleation of the prostatic adenoma (HoLEP) represents an innovative surgical option for the treatment of bladder outlet obstruction caused by benign prostatic hypertrophy. The results of numerous randomized prospective studies and clinical case series have confirmed that HoLEP is a procedure that attai...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:The management of stone disease in renal abnormalities is a challenge for urologist due to its rarity. The aim of the current manuscript is to report our experience in Retrograde Intrarenal Surgery (RIRS) in 4 complex-abdnormal cases using the flexible videoureterorrenoscopy. MATERIAL AND METHODS:Data was pr...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVE:Mondor's disease is a superficial thrombophlebitis and usually occurs in the anterior and lateral chest. The scrotal vein thrombosis is a fairly rare disease. METHODS:Thirty-four year old male who consulted for inguinal tumor and pain in the postoperative period of an umbilical hernia repair, which resulted ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:To report an uncommon clinical case of spontaneous rupture of the superficial dorsal vein of penis. METHOD:A 27-year-old male patient attended the emergency room following spontaneous occurrence of a large hematoma and deformity in the penis. Rupture of cavernous bodies was initially suspected. RESULTS:Surg...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：:We describe a case of recurrent urinary tract infection in a male patient that had been repeatedly associated with sporadic sexual intercourse with his partner. The timing of the episodes and the bacteriological findings indicate this to be another uncommon case of urinary tract infection sexually transmitted by the f...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVES:Laparoscopic surgery in general is handicapped by the reduction of the range of motion from six to four degrees of freedom. This has a major impact on technically difficult procedures such as laparoscopic radical prostatectomy. Solutions for this problems include the understanding of the geometry of laparosc...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the presence of urinary symptoms in 77 patients with multiple sclerosis. METHODS:The neurological compromise and the degree of functional disability were evaluated through the Minimum Dossier of Disability for Multiple Sclerosis. The pertinent data for the urinary symptoms were collected through ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：:The author carries out a sonographic study on 200 expansive kidney processes, in which he assess the possibilities of this method of diagnosis at the same time offering the echographic semiology of the different disorders being studied. Finally, he explains the limitations and drawbacks of this technique. ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1979-07-01 00:00:00
abstract：OBJECTIVE:To determine the correlation between two methods of measurement of total PSA (PSA-T) and free PSA (PSA-F) and the utility of the PSA-F/PSA-T ratio in patients with PSA-T between 4 and 10 ng/ml suspected as having prostate cancer. METHODS:Determinations of both PSA-T and PSA-F were performed using two differe...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To determine the more useful parameters of urethral resistance and bladder contractile power to explain the values of maximum flow and postvoid residual urine observed in free uroflowmetry and appropriately assess the voiding dynamics in childhood. METHODS:A cross-sectional study was carried out in 68 childr...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：INTRODUCTION:Prostate cryotherapy has been consolidated as an alternative minimally invasive treatment. OBJECTIVE:To exposed its historical development, its action mechanism and the surgical technique. Regarding its indications, we expose the different option of treatment- primary cryotherapy, salvage and focal- empha...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVES:An unusual case of malacoplakia is described and the literature reviewed. METHODS/RESULTS:We report on a patient on immunosuppression due to heart transplantation who developed malacoplakia of the epididymis. Patient history and treatment are discussed, with special reference to the differential diagnosis b...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1996-03-01 00:00:00
abstract：:Surgical repair of uretero-enteric strictures in patients with enteric conduit urinary diversion (incidence rate 4-8%) is difficult and has a high morbidity. With the development of endo-urologic techniques and ureteral catheters, long-term insertion of stents in the treatment of strictures has become possible and saf...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the current role of PSA as a diagnostic method for prostate cancer, as well as to analyze possible new markers. METHODS:We perform a bibliographic review for PSA, and its molecular forms, as a marker to define the presence of prostate cancer. We review the factors related to PSA modifications, p...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142006001000014
更新日期：2006-12-01 00:00:00
abstract：:We report 16 cases of priapism in 13 of 404 patients who received intracavernous injection of vasoactive drugs to induce erection. In 10 patients the complication presented following injection of papaverine and phentolamine in combination. Despite reducing the dose of both agents, one patient had another episode of pr...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：OBJECTIVE:Recently, intraoperative floppy-iris syndrome (IFIS) has been related to tamsulosin treatment. This review evaluates the epidemiological evidence of the association of tamsulosin with IFIS and the necessity of a prior ophthalmolo-gic examination in this group of patients. METHOD:Systematic review of the lite...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：10.4321/s0004-06142008000800008
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVE:To analyze the information provided by computed tomography (CT) in Fournier's gangrene, particularly in regard to the early diagnosis of the disease, and its utility as a complementary diagnostic imaging technique. METHODS:A retrospective study identified five cases of Fournier's gangrene. These patients had...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVES:The epidermoid cyst of the testis is a rare benign tumor. It accounts for approximately 1% of all testicular tumors. Generally, the testis has a palpable, painless mass with tumor markers (AFP, BHCG, and LDH) within normal ranges. Pathology reveals a cavity consisting of squamous epithelial cells containing ...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：2004-07-01 00:00:00
abstract：:A case of polyorchism is described and the literature reviewed, highlighting the rarity of this pathological condition. To our knowledge, only 70 cases have been reported in the world literature. Similarly, Nocks' embryological development theory is discussed herein. The present case was diagnosed intraoperatively. No...
journal_title：Archivos espanoles de urologia
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-01 00:00:00
