Improvement in oxygenation by phenylephrine and nitric oxide in patients with adult respiratory distress syndrome.

abstract：:Changes in hepatic plasma flow (HPF) during sodium nitroprusside (SNP) induced hypotension were studied in 14 patients undergoing intracranial aneurysm surgery under neurolept anesthesia. Patients were monitored with the use of a radial artery catheter and a thermistor-tipped Swan-Ganz catheter. Hypotension was induce...

journal_title：Anesthesiology

authors： Chauvin M,Bonnet F,Montembault C,Lafay M,Curet P,Viars P

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Recent evidences have documented that several pharmacologic actions of alpha2-adrenoceptor agonists are mediated via activation of not only alpha2-adrenoceptors, but also by imidazoline receptors, which are nonadrenergic receptors in the central nervous system. However, the effect of imidazoline receptors on...

journal_title：Anesthesiology

authors： Kagawa K,Mammoto T,Hayashi Y,Kamibayashi T,Mashimo T,Yoshiya I

更新日期：1997-10-01 00:00:00

abstract：:Controversy persists about the cardiac toxicity of bupivacaine if accidentally administered intravenously during regional anesthesia. Using awake, unanesthetized sheep, we evaluated the cardiac effects of low and high equivalent doses of lidocaine and bupivacaine given intravenously over 10 s. All animals convulsed wi...

journal_title：Anesthesiology

authors： Kotelko DM,Shnider SM,Dailey PA,Brizgys RV,Levinson G,Shapiro WA,Koike M,Rosen MA

更新日期：1984-01-01 00:00:00

abstract：:The purpose of this study was to evaluate the analgesic contribution of intravenously administered lidocaine and to correlate it with blood levels of the drug. In a double-blind manner, 14 healthy male volunteers received saline solution or lidocaine, 0.2 per cent, at three increasingly greater rates of infusion on tw...

journal_title：Anesthesiology

authors： Rowlingson JC,DiFazio CA,Foster J,Carron H

更新日期：1980-01-01 00:00:00

abstract：:The effect on measured potassium values of a number of factors involved in sample acquisition and preparation were investigated. Measured potassium values in either plasma or serum were not influenced by the site of sample withdrawal, the presence of a tourniquet, or the time elapsed between blood sampling and analysi...

journal_title：Anesthesiology

authors： Hill AB,Nahrwold ML,Noonan D,Northrop P

更新日期：1980-07-01 00:00:00

abstract：:The effect of liposome encapsulation on the analgesia produced by intrathecally administered alfentanil was examined in the rat. In rats prepared with chronic intrathecal catheters, alfentanil in doses of 1-50 micrograms was administered intrathecally in either saline or in multilamellar liposomes (dipalmitoylphosphat...

journal_title：Anesthesiology

authors： Bernards CM,Luger TJ,Malmberg AB,Hill HF,Yaksh TL

更新日期：1992-09-01 00:00:00

abstract：:Positive pressure ventilation can affect hemodynamic stability by neuroreflex-mediated activity. Inhalational anesthesia is known to attenuate the arterial baroreflex function; however, little information is known about the effect of volatile anesthetics on the lung inflation reflex. The influence of isoflurane on sta...

journal_title：Anesthesiology

authors： Cheng EY,Kay J,Hoka S,Bosnjak ZJ,Coon RL,Kampine JP

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:The impact on the endothelial glycocalyx for the extravasation of colloidal infusion solutions has not been investigated sufficiently. METHODS:Isolated guinea pig hearts were perfused with Krebs-Henseleit buffer in a Langendorff mode. Solutions of 0.9% saline, 5% albumin (70 kd), or 6% hydroxyethyl starch (...

journal_title：Anesthesiology

authors： Rehm M,Zahler S,Lötsch M,Welsch U,Conzen P,Jacob M,Becker BF

更新日期：2004-05-01 00:00:00

abstract：:Isoflurane has protective properties during experimental global brain ischemia or hypoxia. However, this has not been evaluated in the more common case of focal ischemia, e.g., as caused by middle cerebral artery occlusion (MCAO). The authors therefore compared the effects of isoflurane, thiopental, and N2O/fentanyl a...

journal_title：Anesthesiology

authors： Nehls DG,Todd MM,Spetzler RF,Drummond JC,Thompson RA,Johnson PC

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Vasospasm of arterial grafts represents an unpredictable complication of coronary artery surgery and may compromise myocardial revascularization, and treatment is based on empirical therapy with nitroglycerin. Because of the potential for tolerance to nitroglycerin to occur, the authors studied different vas...

journal_title：Anesthesiology

authors： Huraux C,Makita T,Montes F,Szlam F,Levy JH

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:The study evaluated the efficacy of recombinant human antithrombin (rhAT) for restoring heparin responsiveness in heparin resistant patients undergoing cardiac surgery. METHODS:This was a multicenter, randomized, double-blind, placebo-controlled study in heparin-resistant patients undergoing cardiac surgery...

journal_title：Anesthesiology

authors： Avidan MS,Levy JH,Scholz J,Delphin E,Rosseel PM,Howie MB,Gratz I,Bush CR,Skubas N,Aldea GS,Licina M,Bonfiglio LJ,Kajdasz DK,Ott E,Despotis GJ

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Nitric oxide released by inducible nitric oxide synthase (iNOS) plays an important role in immune responses and systemic vasodilation in septic shock. Volatile anesthetics have been reported to interfere with signal transduction and gene expression. We studied the effect of volatile anesthetics on activity a...

journal_title：Anesthesiology

authors： Tschaikowsky K,Ritter J,Schröppel K,Kühn M

更新日期：2000-04-01 00:00:00

abstract：:Neuromuscular blockers may affect cerebral blood flow (CBF) regulation in the newborn. We studied the effects of d-tubocurarine (0.1 mg.kg-1, n = 8), pancuronium (0.1 and 0.4 mg.kg-1, n = 6 and 7), and vecuronium (0.1 and 0.4 mg.kg-1, n = 6 and 7) on CBF measured over the same range of mean systemic blood pressure ([B...

journal_title：Anesthesiology

authors： Chemtob S,Barna T,Beharry K,Aranda JV,Varma DR

更新日期：1992-02-01 00:00:00

abstract：:Thiopental-14C (30 mg and 10 muCi/kg) was injected intravenously into rats 36-48 hours following bilateral nephrectomy and one minute after pretreatment with sulfadimethoxine (30 mg/kg, iv). Control groups of normal and sham-operated animals were used. The distributions of radioactivity in plasma, brain, and heart 1, ...

journal_title：Anesthesiology

authors： Ghoneim MM,Pandya HB,Kelley SE,Fischer LJ,Corry RJ

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Hypotension is a common side effect of general anesthesia induction, and when severe, it is related to adverse outcomes. Ultrasonography of inferior vena cava (IVC) is a reliable indicator of intravascular volume status. This study investigated whether preoperative ultrasound IVC measurements could predict h...

journal_title：Anesthesiology

authors： Zhang J,Critchley LA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Pulmonary function is impaired during pneumoperitoneum mainly as a result of atelectasis formation. We studied the effects of 10 cm H2O of positive end-expiratory pressure (PEEP) and PEEP followed by a recruitment maneuver (PEEP+RM) on end-expiratory lung volume (EELV), oxygenation and respiratory mechanics ...

journal_title：Anesthesiology

authors： Futier E,Constantin JM,Pelosi P,Chanques G,Kwiatkoskwi F,Jaber S,Bazin JE

更新日期：2010-12-01 00:00:00

abstract：:Central and peripheral pulmonary mucociliary clearance was assessed by tantalum bronchography and serial chest roentgenograms in dogs. Thiopental, 25 mg/kg, did not change clearance from awake values. Halothane 1.2 MAC, for six hours, delayed both central and peripheral clearance by at least three hours. After halotha...

journal_title：Anesthesiology

authors： Forbes AR,Gamsu G

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Spinal adenosine receptor agonists exert antinociception in animal models of acute and chronic pain, but adenosine itself has not been examined. The authors tested the antinociceptive and antihypersensitivity interactions of intrathecal adenosine and its interactions with intrathecal clonidine and neostigmin...

journal_title：Anesthesiology

authors： Chiari AI,Eisenach JC

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The authors sought to determine whether subjects with pathophysiological conditions that are characterized by increased concentrations of aldosterone have increased susceptibility to the side effects of neonatal anesthesia with sevoflurane. METHODS:Postnatal day 4-20 (P4-P20) rats were exposed to sevofluran...

journal_title：Anesthesiology

authors： Cao W,Pavlinec C,Gravenstein N,Seubert CN,Martynyuk AE

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:An initial pilot study of 300 sub-Tenon local anesthetic blocks (STBs) for intraocular surgery established the effectiveness and patient acceptability of the technique. Following this, a decision was made in 1995 to change from sharp needle techniques to STB for all eye surgeries performed during local anest...

journal_title：Anesthesiology

authors： Guise PA

更新日期：2003-04-01 00:00:00

abstract：:Inorganic fluoride (F-) production and renal function were assessed in six groups of Fischer 344 rats administered either methoxyflurane (MOF) or deuterated methoxyflurane (d4-MOF). One untreated and one phenobarbital (PB)-treated group were exposed for two hours to either air, 0.5 per cent (V/v) MOF, or 0.5 per cent ...

journal_title：Anesthesiology

authors： Baden JM,Rice SA,Mazze RI

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Results from previous studies on the effect of nitrous oxide (N2O) on the cerebral circulation are conflicting. Early reports claim N2O to have no effect whereas recent findings demonstrate a cerebral cortical vasodilatation during N2O inhalation, but the regional cerebral blood flow (CBF) in the subcortical...

journal_title：Anesthesiology

authors： Reinstrup P,Ryding E,Algotsson L,Berntman L,Uski T

更新日期：1994-08-01 00:00:00

abstract：:Chloroprocaine, 0.5 per cent, with physiologic saline solution, has a specific gravity of 1.007 and a osmolarity of 283 mOsm/l, which increase to a specific gravity of 1.025 and an osmolarity of 542 mOsm/l when chloroprocaine is prepared in dextrose, 5 per cent. Chloroprocaine, 2.7 per cent, shows similar increases in...

journal_title：Anesthesiology

authors： Park YR,Eastwood DW

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Studies have shown that permissive hypotension for uncontrolled hemorrhagic shock can result in good resuscitation outcome. The ideal target mean arterial pressure (MAP) and the tolerance time for permissive hypotension have not been determined. METHODS:To elucidate the ideal target MAP and tolerance time f...

journal_title：Anesthesiology

authors： Li T,Zhu Y,Hu Y,Li L,Diao Y,Tang J,Liu L

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Spinal alpha2-adrenoceptor stimulation produces analgesia in neuropathic pain states, and this effect in animals is blocked by the inhibitors of brain-derived neurotrophic factor (BDNF) function. In rats, alpha2-adrenoceptor stimulation normally inhibits acetylcholine release, but it excites release after ...

journal_title：Anesthesiology

authors： Hayashida K,Eisenach JC

更新日期：2010-08-01 00:00:00

abstract：:In order to determine whether or not irritation of the nasal passage with commonly used volatile anesthetics can elicit airway reflexes, we investigated respiratory, laryngeal, and tracheal responses to nasal insufflation of three volatile anesthetics (enflurane, isoflurane, and halothane) in 13 patients anesthetized ...

journal_title：Anesthesiology

authors： Nishino T,Tanaka A,Ishikawa T,Hiraga K

更新日期：1991-09-01 00:00:00

abstract：:The relationship between neuroleptic malignant syndrome (NMS) and malignant hyperthermia (MH) was investigated using the in vitro skeletal muscle contracture test to screen for MH-susceptibility in NMS patients. The maximum contracture tension which developed following exposure to halothane (1-3%), and incremental dos...

journal_title：Anesthesiology

authors： Caroff SN,Rosenberg H,Fletcher JE,Heiman-Patterson TD,Mann SC

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Xenon is a general anesthetic with neuroprotective properties. Xenon inhibition at the glycine-binding site of the N-Methyl-D-aspartate (NMDA) receptor mediates xenon neuroprotection against ischemic injury in vitro. Here we identify specific amino acids important for xenon binding to the NMDA receptor, with...

journal_title：Anesthesiology

authors： Armstrong SP,Banks PJ,McKitrick TJ,Geldart CH,Edge CJ,Babla R,Simillis C,Franks NP,Dickinson R

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Chronic use of μ-opioid receptor agonists paradoxically causes both hyperalgesia and the loss of analgesic efficacy. Opioid treatment increases presynaptic N-methyl-D-aspartate receptor activity to potentiate nociceptive input to spinal dorsal horn neurons. However, the mechanism responsible for this opioid-...

journal_title：Anesthesiology

authors： Deng M,Chen SR,Chen H,Pan HL

更新日期：2019-05-01 00:00:00

abstract：:The authors have previously attributed the mechanism for the 50-67% decrease in the required dose of thiopental for induction of anesthesia in aged human patients to a decrease in the initial distribution volume for thiopental. Using a larger group of patients and volunteers studied in the laboratory, the authors have...

journal_title：Anesthesiology

authors： Stanski DR,Maitre PO

更新日期：1990-03-01 00:00:00