Vascular events after spinal cord injury: contribution to secondary pathogenesis.

Abstract:

:Traumatic spinal cord injury results in the disruption of neural and vascular structures (primary injury) and is characterized by an evolution of secondary pathogenic events that collectively define the extent of functional recovery. This article reviews the vascular responses to spinal cord injury, focusing on both early and delayed events, including intraparenchymal hemorrhage, inflammation, disruption of the blood-spinal cord barrier, and angiogenesis. These vascular-related events not only influence the evolution of secondary tissue damage but also define an environment that fosters neural plasticity in the chronically injured spinal cord.

journal_name

Phys Ther

journal_title

Physical therapy

authors

Mautes AE,Weinzierl MR,Donovan F,Noble LJ

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

673-87

issue

7

eissn

0031-9023

issn

1538-6724

journal_volume

80

pub_type

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