Abstract:
:Major focuses of geriatric medicine are cardiovascular diseases with increases in prevalence in older people and how aging might modify the risk factors, clinical manifestations, treatment strategies, and prognoses of these diseases. Quantitative information on age-associated alterations in cardiovascular structure and function in health is essential to define and target the specific characteristics of the cardiovascular aging process that render it the major risk factor for cardiovascular diseases. Such information also is required to differentiate among the limitations of elderly individuals that relate to disease and limitations that may fall within expected normal limits. Differences in cardiovascular function between older and younger individuals have been described extensively in the literature, but confusion often arises in the interpretation of these differences because of a failure to acknowledge or to control for interactions among age, disease, and lifestyle. The Baltimore Longitudinal Study on Aging has made an effort to characterize the effects of aging on multiple aspects of cardiovascular structure and function. The concepts that have evolved from this and other studies are discussed.
journal_name
Clin Geriatr Medjournal_title
Clinics in geriatric medicineauthors
Lakatta EGdoi
10.1016/s0749-0690(05)70021-5subject
Has Abstractpub_date
2000-08-01 00:00:00pages
419-44issue
3eissn
0749-0690issn
1879-8853pii
S0749-0690(05)70021-5journal_volume
16pub_type
杂志文章,评审abstract::Normal aging is associated with a multitude of changes in the cardiovascular system, including decreased compliance of blood vessels, mild concentric left ventricular hypertrophy, an increased contribution of atrial contraction to left ventricular filling, and a higher incidence of many cardiac arrhythmias, both brady...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2012.07.003
更新日期:2012-11-01 00:00:00
abstract::Depression is one of the most serious and prevalent neuropsychiatric disorders of old age. Despite its prevalence, depression in the aged is frequently unrecognized or is misdiagnosed. This article reviews the existing knowledge of several sleep-related areas and discusses possible future studies into sleep as a progn...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-05-01 00:00:00
abstract::When the elderly are afflicted by malignancy, chances are good that at some point in the course of their illness the skeleton will be involved. Bone metastases, hypercalcemia, and other paraneoplastic syndromes are commonly encountered and require definitive diagnosis and management. In general, the therapy for the el...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1987-08-01 00:00:00
abstract::Many health care professionals lack knowledge about artificial nutrition and hydration at the end of life or may hold different attitudes about artificial nutrition and hydration compared with other treatments. Consequently, they may convey inaccurate or misleading information to patients or their surrogate decision m...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(05)70058-6
更新日期:2000-05-01 00:00:00
abstract::Half of all lung cancers occur in persons aged 65 years and older. The symptoms of lung cancer in the elderly may be nonspecific and misleading. Age trends in incidence, histologic subtype, and stage suggest that selective screening of older persons for lung cancer should be studied. Recent data reveal that the mortal...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1987-11-01 00:00:00
abstract::Geriatric patients are at a high risk for the development of postoperative delirium. By recognizing predisposing and precipitating risk factors, preventive measures can be undertaken to reduce this risk. Accurate and timely diagnosis is essential, and we offer therapeutic strategies to help reduce the high morbidity a...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2008.06.002
更新日期:2008-11-01 00:00:00
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journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1986-08-01 00:00:00
abstract::Transitions in care are a vulnerable time period for patients during which unintended errors may occur. This article discusses potential risks that could occur during care transitions, suggested improvements, and the transition from hospital to skilled nursing facilities for patients needing rehabilitation after their...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2014.01.017
更新日期:2014-05-01 00:00:00
abstract::Pain is a common problem encountered among elderly people in subacute and long-term care facilities. Pain often is underestimated and undertreated in these settings. Most pain problems can be improved by careful assessment and careful use of analgesic drugs and nondrug strategies. Subacute care and other long-term car...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(05)70048-3
更新日期:2000-11-01 00:00:00
abstract::Older adults receive care from various settings, including acute care hospitals, skilled nursing facilities, nursing homes, group homes, outpatient primary care, specialty clinics, and home. In these various settings, older adults are exposed to pathogens, which makes them "vectors" that transport pathogens from one s...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2007.02.001
更新日期:2007-08-01 00:00:00
abstract::In summary, herbs are commonly used, and it is the physician's responsibility to have better documentation of this practice by encouraging patients to report use of herbs, and to look for any unusual side effects that can occur in terms of herb-drug or herb-herb interactions. ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2004.02.009
更新日期:2004-05-01 00:00:00
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journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1997-11-01 00:00:00
abstract::Gait disorders in elderly individuals are a major cause of falls and their attendant morbidities. Ataxia is one of the neurologic components of fall risk, as are inattention or confusion, visual impairment, vestibular impairment, subcortical white matter disease, parkinsonism, weakness, sensory loss, orthostasis or ar...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2006.06.011
更新日期:2006-11-01 00:00:00
abstract::The pathophysiology of stone disorder in older adults, as compared to their younger counterparts, has not been thoroughly investigated. This article examines the differences in serum and urine chemistries between groups that are younger and older than 60 years of age. The principal finding is that stone formation occu...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract::In developing and validating the concept of frailty as a geriatric syndrome, it has been necessary to distinguish the clinical expression of frailty from normal age-related changes and other age-related disease pathologies. A framework for excluding potentially confounding disease and a working clinical tool to diagno...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章
doi:10.1016/j.cger.2010.08.006
更新日期:2011-02-01 00:00:00
abstract::Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Sjögren syndrome is the prototypic disease associat...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2016.08.007
更新日期:2017-02-01 00:00:00
abstract::There is strong evidence supporting the benefit of antihypertensive treatment in older patients. Blood pressure goal and drug selection in the elderly is similar to that in younger populations, but there are a few special considerations in these patients. A number of studies have been conducted to determine the drugs ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2009.03.001
更新日期:2009-05-01 00:00:00
abstract::A comprehensive practical approach to the diagnosis, staging, and treatment of carcinoma of the prostate is presented. Prostatic cancer in the elderly patient is not a benign clinical condition. The approach is designed to minimize the morbidity of the disease process and to allow the patient to live as normal a life ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract::Healthy aging is a process that occurs over the life cycle. Health habits established early and practiced throughout life impact longevity, the ability to reach old age, and the health with which one experiences older adulthood. The new field of lifestyle medicine addresses root causes of disease by targeting nutritio...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2020.06.007
更新日期:2020-11-01 00:00:00
abstract::Efforts toward early detection of Alzheimer disease (AD) have focused on refinement and identification of diagnostic markers, with the goal of preventing or delaying disease progression. Mild cognitive impairment (MCI) has emerged as a potential precursor to dementia. Though not without controversy, MCI has been assoc...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2013.07.008
更新日期:2013-11-01 00:00:00
abstract::The utility of cardiac rehabilitation for elderly cardiac patients is controversial, and cost, logistic barriers, and encumbering comorbidities often seem disproportionate. Many clinicians view the emphasis of cardiac rehabilitation on behavior modification and risk-factor reduction as irrelevant for very old adults a...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(05)70031-8
更新日期:2000-08-01 00:00:00
abstract::Skin ulcers of the lower extremities have a chronic, relapsing course and often are difficult to manage. Leg ulcers remain a significant management challenge to health care professionals. This article focuses on the various causes of leg ulcers, with an emphasis on venous disease. Characteristic clinical findings and ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(03)00035-1
更新日期:2002-02-01 00:00:00
abstract::Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia following Alzheimer disease. It stems from the formation of Lewy bodies, which contain aggregates of the misfolded protein, α-synuclein. These deposit in areas of the nervous system and brain, leading to neuronal cell death and causin...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2018.06.007
更新日期:2018-11-01 00:00:00
abstract::This review focuses on studies that pertain to obesity and aging. The prevalence of obesity in the elderly is discussed, with an emphasis on body-fat distribution as it relates to morbidity and mortality rates. Treatment options, such as physical activity, growth hormones, and drug therapy, are briefly mentioned. A se...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1999-05-01 00:00:00
abstract::Elderly patients with cardiovascular disease require slightly different management strategies compared with younger patients. Diagnosis is more difficult. Procedures, both diagnostic and therapeutic, are more dangerous. Despite higher risks, elderly patients have much to gain from aggressive therapies such as angiopla...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1994-02-01 00:00:00
abstract::Treatment of alcohol dependence among older alcoholic patients should be multidimensional to address as many potential relapse factors as possible. As the literature suggests, alcohol-related disorders often are under diagnosed and under treated. More efforts are needed to identify and improve diagnosis of these disor...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(03)00045-4
更新日期:2003-11-01 00:00:00
abstract::Urinary incontinence (UI) in the older adult is a multisystem health problem that has an impact on the lives of millions of older adults. Advanced practice nurses (APNs) specializing in gerontology,family, and adult practice are equipped educationally with the expertise to prevent, assess, and manage this health probl...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2004.04.015
更新日期:2004-08-01 00:00:00
abstract::Lifespans worldwide continue to get progressively longer as we learn more about the science of aging, adopt more healthy lifestyles, and develop better technology to promote successful longevity. Unfortunately, with advanced age comes bone loss and an increased risk for skeletal fractures. Much is known about age-rela...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1994-11-01 00:00:00
abstract::This article provides a brief overview of the challenges and opportunities of new technologies in the area of geriatric pain management. It also reviews emerging evidence to demonstrate the role technology may play in improving and advancing assessment and management of pain in older adults. ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2016.06.011
更新日期:2016-11-01 00:00:00
abstract::Primary malignant brain tumors present a formidable challenge to surgeons, patients, and families. Although the prognosis in elderly patients approaches only 6 months, aggressive resection and adjuvant treatment may be indicated in a select group of patients who have preserved functional status. Subdural hematomas in ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2006.04.002
更新日期:2006-08-01 00:00:00