The biology of aging and frailty.

abstract：:Falling is often a multifactorial syndrome that can be viewed from several perspectives, including pathophysiologic, biomedical, functional, and ecologic models. The history, physical examination, and performance testing are the cornerstones of evaluation. Diagnostic testing in selected cases and environmental evaluat...

journal_title：Clinics in geriatric medicine

authors： Studenski S,Rigler SK

更新日期：1996-11-01 00:00:00

abstract：:Early Parkinson disease is the approximate time period between initial diagnosis and the onset of motor fluctuations. Treatment requires an integrative approach, including identification of motor and nonmotor symptoms, choice of pharmacologic treatment, and emphasis on exercise. Patients should be treated for motor sy...

journal_title：Clinics in geriatric medicine

authors： Zesiewicz TA,Bezchlibnyk Y,Dohse N,Ghanekar SD

更新日期：2020-02-01 00:00:00

abstract：:Bone is a complex organ which contains an organic matrix which serves as scaffolding, includes mineral as calcium distributed in a pattern providing structure and serves as an ion reservoir for the body. Throughout life it dynamically changes in response to changes in activity, body mass, and weight bearing. It is imp...

journal_title：Clinics in geriatric medicine

authors： Simon LS

更新日期：2005-08-01 00:00:00

abstract：:Approximately one in three Americans has some form of cardiovascular disease (CVD), accounting for one of every 2.8 deaths in the United States in 2004. Two of the major risk factors for CVD are advancing age and obesity. An intervention able to positively impact both aging and obesity, such as caloric restriction (CR...

journal_title：Clinics in geriatric medicine

authors： Cruzen C,Colman RJ

更新日期：2009-11-01 00:00:00

abstract：:Urinary incontinence (UI) in the older adult is a multisystem health problem that has an impact on the lives of millions of older adults. Advanced practice nurses (APNs) specializing in gerontology,family, and adult practice are equipped educationally with the expertise to prevent, assess, and manage this health probl...

journal_title：Clinics in geriatric medicine

authors： Cacchione PZ,Decker SA

更新日期：2004-08-01 00:00:00

abstract：:This article summarizes the common, superficial, cutaneous, fungal infections that are found in older adults. The epidemiology, classic appearance, and current treatments of these fungal infections are discussed. These common skin pathogens occur in many older adults. ...

journal_title：Clinics in geriatric medicine

authors： Varade RS,Burkemper NM

更新日期：2013-05-01 00:00:00

abstract：:Urinary incontinence is a prevalent condition in elderly women with significant associated morbidity. Incontinence can by grouped into several types: stress incontinence, urgency incontinence, overflow incontinence, functional incontinence, and mixed urinary incontinence. Careful evaluation, including history and phys...

journal_title：Clinics in geriatric medicine

authors： Parker WP,Griebling TL

更新日期：2015-11-01 00:00:00

abstract：:Epidemiological data suggests that the prevalence of musculoskeletal and neuropathic pain increases with age until at least late mid-life, though the pattern is somewhat unclear beyond this point. And though the prevalence of some types of pain may peak in late midlife, pain is still a substantial and common complaint...

journal_title：Clinics in geriatric medicine

authors： Savvas SM,Gibson SJ

更新日期：2016-11-01 00:00:00

abstract：:Although exercise capacity declines with age, the decline appears to be slight when measured in healthy, physically active subjects. There is growing evidence that exercise has a positive influence on increasing healthy function and decreasing the impact of diseases common in the elderly. While the dose-response relat...

journal_title：Clinics in geriatric medicine

authors： Gorman KM,Posner JD

更新日期：1988-02-01 00:00:00

abstract：:Pain is a common problem encountered among elderly people in subacute and long-term care facilities. Pain often is underestimated and undertreated in these settings. Most pain problems can be improved by careful assessment and careful use of analgesic drugs and nondrug strategies. Subacute care and other long-term car...

journal_title：Clinics in geriatric medicine

authors： Ferrell BA

更新日期：2000-11-01 00:00:00

abstract：:Many health care professionals lack knowledge about artificial nutrition and hydration at the end of life or may hold different attitudes about artificial nutrition and hydration compared with other treatments. Consequently, they may convey inaccurate or misleading information to patients or their surrogate decision m...

journal_title：Clinics in geriatric medicine

authors： Huang ZB,Ahronheim JC

更新日期：2000-05-01 00:00:00

abstract：:Aging implies changes in joint components over a continuum of time that contribute later in life to an increasing frequency of clinical complaints and impairments in function and mobility. This article considers how aging appears to modify the articular cartilage, subchondral bone, muscle, the soft tissues, synovial m...

journal_title：Clinics in geriatric medicine

authors： Hamerman D

更新日期：1998-08-01 00:00:00

abstract：:Gait disorders in elderly individuals are a major cause of falls and their attendant morbidities. Ataxia is one of the neurologic components of fall risk, as are inattention or confusion, visual impairment, vestibular impairment, subcortical white matter disease, parkinsonism, weakness, sensory loss, orthostasis or ar...

journal_title：Clinics in geriatric medicine

authors： Perlman SL

更新日期：2006-11-01 00:00:00

abstract：:By most clinical and economic measures, our health care system is not providing effective or affordable care to Medicare beneficiaries with severe chronic illness. Two million elders, constituting most of the 5% who account for nearly half of Medicare costs, have multiple chronic conditions, functional disability, and...

journal_title：Clinics in geriatric medicine

authors： DeJonge KE,Taler G,Boling PA

更新日期：2009-02-01 00:00:00

abstract：:The routine prescription of hormone replacement therapy for elderly women to prevent heart disease is not indicated. Until better data are available, the use of estrogens primarily to prevent heart disease probably should be reserved for women at high risk by virtue of their LDL/HDL ratio or the presence of manifest c...

journal_title：Clinics in geriatric medicine

authors： Barrett-Connor E,Miller V

更新日期：1993-02-01 00:00:00

abstract：:The elderly have more organic sleep problems disturbing sleep and contributing to insomnia than younger individuals. The most common disorders afflicting the elderly are obstructive sleep apnea, restless legs syndrome, and nocturnal myoclonus. Poor sleep habits often aggravate or contribute to the ongoing difficulty w...

journal_title：Clinics in geriatric medicine

authors： Wooten V

更新日期：1992-05-01 00:00:00

abstract：:Postprandial hypotension is a prevalent condition in the elderly population and seems to be more common in frail elderly individuals who may be more susceptible to complications such as syncope and falls. Diagnosis is relatively easy and may be reversible in many cases. The epidemiology and pathophysiology of postpran...

journal_title：Clinics in geriatric medicine

authors： O'Mara G,Lyons D

更新日期：2002-05-01 00:00:00

abstract：:Footwear is a modifiable risk factor for falls in older adults, including populations with metabolic disease, inflammatory arthritis, and neurodegenerative disease. Ill-fitting footwear, and specific design features, such as elevated heels and backless styles, can impair balance control and heighten the risk of fallin...

journal_title：Clinics in geriatric medicine

authors： Hatton AL,Rome K

更新日期：2019-05-01 00:00:00

abstract：:Although the increased need for studies assessing the influence of age on the pharmacokinetics and pharmacodynamics of all drugs has been emphasized, relatively little is known about NSAIDs in the elderly. The pharmacokinetics of some NSAIDs have been examined in elderly subjects; unfortunately, recent data indicate t...

journal_title：Clinics in geriatric medicine

authors： Murray MD,Brater DC

更新日期：1990-05-01 00:00:00

abstract：:This review focuses on studies that pertain to obesity and aging. The prevalence of obesity in the elderly is discussed, with an emphasis on body-fat distribution as it relates to morbidity and mortality rates. Treatment options, such as physical activity, growth hormones, and drug therapy, are briefly mentioned. A se...

journal_title：Clinics in geriatric medicine

authors： Kotz CM,Billington CJ,Levine AS

更新日期：1999-05-01 00:00:00

abstract：:Older patients with cancer are best served by a multidisciplinary approach with palliative care (PC) playing an integral role. PC focuses on symptom control irrespective of its cause and should not be associated only with terminal care. It provides an additional layer of support in the care of patients with cancer wit...

journal_title：Clinics in geriatric medicine

authors： Alexander K,Goldberg J,Korc-Grodzicki B

更新日期：2016-02-01 00:00:00

abstract：:Nighttime sleep disruption is characteristic of long-term care residents, is typically accompanied by daytime sleepiness, and may be caused by a multitude of factors. Causal factors include medical and psychiatric illness, medications, circadian rhythm abnormalities, sleep disordered breathing and other primary sleep ...

journal_title：Clinics in geriatric medicine

authors： Martin JL,Ancoli-Israel S

更新日期：2008-02-01 00:00:00

abstract：:Balance disorders are common in the elderly and can lead to falls, with resultant severe morbidity and even mortality. Progressive loss of vestibular function begins in middle age and is affected by multiple disease processes. Polypharmacy impacts many disease processes in the elderly, with balance function being one ...

journal_title：Clinics in geriatric medicine

authors： Eibling D

更新日期：2018-05-01 00:00:00

abstract：:Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Sjögren syndrome is the prototypic disease associat...

journal_title：Clinics in geriatric medicine

authors： Baer AN,Walitt B

更新日期：2017-02-01 00:00:00

abstract：:In attempting to understand the role of visual perception in falls and their prevention, the relationship between the locomoting individual and the surrounding environment must be considered. Falls will occur when necessary properties of the environment and visual sources of information about them are inadequate, or w...

journal_title：Clinics in geriatric medicine

authors： Owen DH

更新日期：1985-08-01 00:00:00

abstract：:Cardiovascular disorders are a common cause of falls and syncope in older adults. The most common cardiac disorders linked to falls and syncope are carotid sinus syndrome, postprandial hypotension, orthostatic hypotension, vasovagal syncope, and bradyarrhythmias. It is important to recognize these conditions, because ...

journal_title：Clinics in geriatric medicine

authors： Cronin H,Kenny RA

更新日期：2010-11-01 00:00:00

abstract：:Elderly individuals, worldwide, are on the rise, posing new challenges to care providers. Hypertension is highly prevalent in elderly individuals, and multiple challenges face care providers while managing it. In addition to treating hypertension, the physician must treat other modifiable cardiovascular risk factors i...

journal_title：Clinics in geriatric medicine

authors： Turgut F,Yesil Y,Balogun RA,Abdel-Rahman EM

更新日期：2013-08-01 00:00:00

abstract：:Parkinson disease is a complex, age-related, neurodegenerative disease associated with dopamine deficiency and both motor and nonmotor deficits. Many environmental and genetic factors influence Parkinson disease risk, with different factors predominating in different patients. These factors converge on specific pathwa...

journal_title：Clinics in geriatric medicine

authors： Simon DK,Tanner CM,Brundin P

更新日期：2020-02-01 00:00:00

abstract：:This article reviews the clinical manifestations, diagnostic criteria, and treatment strategies for the acute leukemias, the myelodysplastic syndrome, Hodgkin's disease, and the non-Hodgkin's lymphomas in the elderly. These are relatively common diseases in the elderly, and age is traditionally thought to be a bad pro...

journal_title：Clinics in geriatric medicine

authors： Antin JH,Rosenthal DS

更新日期：1985-11-01 00:00:00

abstract：:Aspirin in a dose of 160 to 325 mg should be administered on day 1 of an acute MI and continued indefinitely on a daily basis. Thrombolytic therapy should be administered within 6 to 12 hours after the onset of an acute MI with ST segment elevation or with left bundle branch block. Primary coronary angioplasty when av...

journal_title：Clinics in geriatric medicine

authors： Aronow WS

更新日期：2001-02-01 00:00:00