Estrogens, lipids, and heart disease.

Abstract:

:The routine prescription of hormone replacement therapy for elderly women to prevent heart disease is not indicated. Until better data are available, the use of estrogens primarily to prevent heart disease probably should be reserved for women at high risk by virtue of their LDL/HDL ratio or the presence of manifest coronary heart disease. There is no reason to give progestins to the woman without a uterus; unopposed oral estrogen should improve lipoproteins within a few weeks, and this change, if sustained, should reduce risk. The management of a woman with an intact uterus is more problematic given the unknowns about progestin's long-term effects on lipids or the heart and the unwillingness of many elderly women to resume regular (or irregular) bleeding. There are, however, many proven benefits of hormone replacement therapy, including the prevention of osteoporosis and urogenital atrophy. Decisions about when it is too late to start estrogen, or when it is time to stop it, will need to be made on a case-by-case basis.

journal_name

Clin Geriatr Med

authors

Barrett-Connor E,Miller V

subject

Has Abstract

pub_date

1993-02-01 00:00:00

pages

57-67

issue

1

eissn

0749-0690

issn

1879-8853

journal_volume

9

pub_type

杂志文章,评审
  • Malignant skeletal neoplasms in the geriatric patient.

    abstract::Malignant neoplasms of the geriatric skeleton are either primary or metastatic in nature. The vast majority are metastatic to the skeleton from carcinomas. Rarely, a primary skeletal malignancy, usually a chondrosarcoma or a malignant fibrous histiocytoma, develops in the geriatric patient. This article discusses the ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章

    doi:

    authors: McGuire DJ,McGuire MH

    更新日期:1994-11-01 00:00:00

  • Colorectal cancer.

    abstract::Colorectal cancer is one of the leading causes of death in older men and women. Therefore, this age-related cancer is of particular importance to geriatricians. The high incidence of this cancer may be decreased by dietary modifications recommended by the American Cancer Society. Early cancer detection is important to...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Neilan BA

    更新日期:1987-11-01 00:00:00

  • Stroke rehabilitation in nursing homes: how do we measure quality?

    abstract::Over one-third of Medicare stroke patients are admitted to nursing homes for rehabilitation. Patients with stroke who are admitted to nursing homes are extremely heterogeneous, including both those with minimal physical and cognitive impairment and those who are totally physically dependent. Quality measures that are ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Kramer AM,Coleman EA

    更新日期:1999-11-01 00:00:00

  • Lung cancer in the elderly.

    abstract::Half of all lung cancers occur in persons aged 65 years and older. The symptoms of lung cancer in the elderly may be nonspecific and misleading. Age trends in incidence, histologic subtype, and stage suggest that selective screening of older persons for lung cancer should be studied. Recent data reveal that the mortal...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: O'Rourke MA,Crawford J

    更新日期:1987-11-01 00:00:00

  • Herbal therapies.

    abstract::In summary, herbs are commonly used, and it is the physician's responsibility to have better documentation of this practice by encouraging patients to report use of herbs, and to look for any unusual side effects that can occur in terms of herb-drug or herb-herb interactions. ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2004.02.009

    authors: Tariq SH

    更新日期:2004-05-01 00:00:00

  • The effect of type 2 diabetes on body composition of older adults.

    abstract::This review describes the effect of type 2 diabetes on fat mass, fat distribution, and lean mass, and changes in these parameters, in older adults, focusing on observational studies. Studies show that type 2 diabetes is associated with an unfavorable body composition characterized by more visceral fat, less thigh subc...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2014.08.020

    authors: Koster A,Schaap LA

    更新日期:2015-02-01 00:00:00

  • Diet and diabetes in the elderly.

    abstract::This article draws attention to some of the unique aspects of diabetes mellitus in the elderly and outlines the principles of management of diabetes in this age group with emphasis on diet therapy. The implications of the Diabetes Control and Complications Trial for the elderly person with diabetes is also briefly dis...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Fonseca V,Wall J

    更新日期:1995-11-01 00:00:00

  • Effects of caloric restriction on cardiovascular aging in non-human primates and humans.

    abstract::Approximately one in three Americans has some form of cardiovascular disease (CVD), accounting for one of every 2.8 deaths in the United States in 2004. Two of the major risk factors for CVD are advancing age and obesity. An intervention able to positively impact both aging and obesity, such as caloric restriction (CR...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2009.07.001

    authors: Cruzen C,Colman RJ

    更新日期:2009-11-01 00:00:00

  • Cancer of the oldest old. What we have learned from autopsy studies.

    abstract::Cancer in the oldest old is a novel problem, due to the recent burgeoning of the population aged 85 and older. This article addresses three critical questions related to cancer in the oldest old: Does the incidence of cancer increase after age 95? Is cancer a common cause of death for the oldest old? Is cancer accurat...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Stanta G,Campagner L,Cavallieri F,Giarelli L

    更新日期:1997-02-01 00:00:00

  • Falls, Footwear, and Podiatric Interventions in Older Adults.

    abstract::Footwear is a modifiable risk factor for falls in older adults, including populations with metabolic disease, inflammatory arthritis, and neurodegenerative disease. Ill-fitting footwear, and specific design features, such as elevated heels and backless styles, can impair balance control and heighten the risk of fallin...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2018.12.001

    authors: Hatton AL,Rome K

    更新日期:2019-05-01 00:00:00

  • Neurosurgery in the elderly: brain tumors and subdural hematomas.

    abstract::Primary malignant brain tumors present a formidable challenge to surgeons, patients, and families. Although the prognosis in elderly patients approaches only 6 months, aggressive resection and adjuvant treatment may be indicated in a select group of patients who have preserved functional status. Subdural hematomas in ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2006.04.002

    authors: Roger EP,Butler J,Benzel EC

    更新日期:2006-08-01 00:00:00

  • Rapid Depression Assessment in Geriatric Patients.

    abstract::Depression is common in geriatric patients, especially in those with multiple comorbidities and polypharmacy. Depression in older adults is often underdiagnosed and undertreated. Initial screening for depression can easily be accomplished in the waiting room. Yet the clinical interview still remains the gold standard ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2017.03.007

    authors: Grossberg GT,Beck D,Zaidi SNY

    更新日期:2017-08-01 00:00:00

  • Sarcopenia.

    abstract::The definition of sarcopenia continues to evolve, from an observational phenomenon to a differential diagnostic approach. Clinical relevance for sarcopenia is defined by a loss in lean muscle mass and impairment of functional status. A therapeutic approach to the loss of skeletal muscle mass and strength in older pers...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章

    doi:10.1016/j.cger.2010.02.012

    authors: Thomas DR

    更新日期:2010-05-01 00:00:00

  • Carotid endarterectomy for stroke prevention in older people.

    abstract::The efficacy of endarterectomy for patients with symptomatic high-grade stenosis of the extracranial carotid artery has been firmly established. Those with asymptomatic carotid disease may also be candidates for the operation. A thorough understanding of the benefits and risks of the operation for the individual patie...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Goldstein LB

    更新日期:1999-11-01 00:00:00

  • Diagnosis and management of intracerebral hemorrhage in elderly patients.

    abstract::An analysis of the risk factors and clinical presentation of intracerebral hemorrhage in the elderly is provided. Specific pathogenic mechanisms that apply to the elderly, such as cerebral amyloid angiopathy, are discussed in detail. General management of intracerebral hemorrhage is discussed, along with specific issu...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Kase CS

    更新日期:1991-08-01 00:00:00

  • Infection control issues in older adults.

    abstract::Older adults receive care from various settings, including acute care hospitals, skilled nursing facilities, nursing homes, group homes, outpatient primary care, specialty clinics, and home. In these various settings, older adults are exposed to pathogens, which makes them "vectors" that transport pathogens from one s...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2007.02.001

    authors: Mody L

    更新日期:2007-08-01 00:00:00

  • Urinary tract infections in the elderly.

    abstract::Urinary infection is the most common infection in elderly populations. There is a high prevalence of asymptomatic bacteriuria, but this is benign and does not require treatment. A urine specimen for culture should be obtained before initiating antimicrobial therapy for symptomatic infection. Antimicrobial treatment re...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2009.04.005

    authors: Nicolle LE

    更新日期:2009-08-01 00:00:00

  • Peritonitis.

    abstract::Intraperitoneal infections or inflammatory disease in elderly patients are a diagnostic challenge that will be encountered with increasing frequency in the aging population of the United States. Diagnostic clues are not overt and frequently appear late in the course of the disease. Confusion and subtle changes in clin...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Hill AB,Meakins JL

    更新日期:1992-11-01 00:00:00

  • Hispanic-American elders. Implications for health-care providers.

    abstract::American health-care practitioners are faced with a rapidly growing, geriatric, Hispanic-American population. This group shares certain cultural links but is largely heterogeneous and comprised of many subgroups, the largest of which are Mexican Americans, Puerto Ricans, and Cuban Americans. Health-care practitioners ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Pousada L

    更新日期:1995-02-01 00:00:00

  • Radioisotopes and their use in the diagnosis and management of thyroid disease.

    abstract::The use of radioactive isotopes in thyroid evaluation and therapy gives important information in the endocrine assessment of the aged. Thyroid uptake imaging can be used to establish a hypothyroid or hyperthyroid state and can determine the functional status of a palpable nodule. Investigational agents, such as T1 201...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Freeman SJ,Girolamo RF

    更新日期:1995-05-01 00:00:00

  • Diagnosis and treatment of alcohol dependence in older alcoholics.

    abstract::Treatment of alcohol dependence among older alcoholic patients should be multidimensional to address as many potential relapse factors as possible. As the literature suggests, alcohol-related disorders often are under diagnosed and under treated. More efforts are needed to identify and improve diagnosis of these disor...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-0690(03)00045-4

    authors: Sattar SP,Petty F,Burke WJ

    更新日期:2003-11-01 00:00:00

  • Surgical management of complicated diverticulitis.

    abstract::The majority of patients with acute diverticulitis can be managed medically. Some will have a complication of diverticulitis such as free perforation with peritonitis, abscess formation, obstruction, or fistula formation. Perhaps even a larger number will develop recurrent diverticulitis, which is associated with an i...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章

    doi:

    authors: Symmonds RE Jr

    更新日期:1985-05-01 00:00:00

  • End-of-life care: an agenda for policy improvement.

    abstract::Current arrangements for health care in the United States do not adequately address the needs of a growing population that has serious, eventually fatal chronic illness. New programs and policies are necessary to encourage coordination of care; better match services to the needs of patients; better provide education a...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章

    doi:10.1016/j.cger.2004.08.008

    authors: Shugarman LR,Lorenz K,Lynn J

    更新日期:2005-02-01 00:00:00

  • Reflux and acid peptic diseases in the elderly.

    abstract::Gastroesophageal reflux disease (GERD) is a common disorder among elderly patients seeking medical care. Diagnosis and management of GERD in the older patient is a unique challenge for both the primary care provider and the gastroenterologist. Such patients may have atypical symptoms, more severe disease, and a higher...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2013.10.006

    authors: Soumekh A,Schnoll-Sussman FH,Katz PO

    更新日期:2014-02-01 00:00:00

  • Nonsurgical Treatment of Urinary Incontinence in Elderly Women.

    abstract::Urinary incontinence is a prevalent condition in elderly women with significant associated morbidity. Incontinence can by grouped into several types: stress incontinence, urgency incontinence, overflow incontinence, functional incontinence, and mixed urinary incontinence. Careful evaluation, including history and phys...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2015.07.003

    authors: Parker WP,Griebling TL

    更新日期:2015-11-01 00:00:00

  • Nutrition and hydration in terminally ill patients: an update.

    abstract::Many health care professionals lack knowledge about artificial nutrition and hydration at the end of life or may hold different attitudes about artificial nutrition and hydration compared with other treatments. Consequently, they may convey inaccurate or misleading information to patients or their surrogate decision m...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-0690(05)70058-6

    authors: Huang ZB,Ahronheim JC

    更新日期:2000-05-01 00:00:00

  • Psychomotor assessment of the older patient.

    abstract::Psychomotor assessment is a collaborative effort between the neurologic and the neuropsychologic evaluation. Changes associated with normal aging must be differentiated from signs and symptoms that indicate abnormal functioning. Recent developments in computer-based technology should add to the precision and accuracy ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Mahurin RK,Inbody SB

    更新日期:1989-08-01 00:00:00

  • Nonpharmacologic interventions. Exercise, fall prevention, and role of physical medicine.

    abstract::Musculoskeletal changes that are related to osteoporosis can be prevented, challenged, or reduced with implementation of proper rehabilitation programs. The nonpharmacologic interventions recommended here are evidence-based and have resulted from controlled trials and studies. ...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0749-0690(02)00111-8

    authors: Sinaki M

    更新日期:2003-05-01 00:00:00

  • Benefits of exercise in old age.

    abstract::Although exercise capacity declines with age, the decline appears to be slight when measured in healthy, physically active subjects. There is growing evidence that exercise has a positive influence on increasing healthy function and decreasing the impact of diseases common in the elderly. While the dose-response relat...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Gorman KM,Posner JD

    更新日期:1988-02-01 00:00:00

  • Gastroesophageal Reflux Disease and Barrett Esophagus in the Elderly.

    abstract::As our population continues to age, the early diagnosis and optimal management of patients with gastroesophageal reflux disease becomes paramount. Maintaining a low threshold for evaluating atypical symptoms in this population is key to improving outcomes. Should patients develop complications including severe esophag...

    journal_title:Clinics in geriatric medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.cger.2020.08.003

    authors: Otaki F,Iyer PG

    更新日期:2021-02-01 00:00:00