Abstract:
:Approximately one in three Americans has some form of cardiovascular disease (CVD), accounting for one of every 2.8 deaths in the United States in 2004. Two of the major risk factors for CVD are advancing age and obesity. An intervention able to positively impact both aging and obesity, such as caloric restriction (CR), may prove extremely useful in the fight against CVD. CR is the only environmental or lifestyle intervention that repeatedly has been shown to increase maximum life span and to retard aging in laboratory rodents. This article reviews evidence that CR in nonhuman primates and people has a positive effect on risk factors for CVD.
journal_name
Clin Geriatr Medjournal_title
Clinics in geriatric medicineauthors
Cruzen C,Colman RJdoi
10.1016/j.cger.2009.07.001subject
Has Abstractpub_date
2009-11-01 00:00:00pages
733-43, ix-xissue
4eissn
0749-0690issn
1879-8853pii
S0749-0690(09)00057-3journal_volume
25pub_type
杂志文章,评审abstract::Lifespans worldwide continue to get progressively longer as we learn more about the science of aging, adopt more healthy lifestyles, and develop better technology to promote successful longevity. Unfortunately, with advanced age comes bone loss and an increased risk for skeletal fractures. Much is known about age-rela...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1994-11-01 00:00:00
abstract::Musculoskeletal changes that are related to osteoporosis can be prevented, challenged, or reduced with implementation of proper rehabilitation programs. The nonpharmacologic interventions recommended here are evidence-based and have resulted from controlled trials and studies. ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(02)00111-8
更新日期:2003-05-01 00:00:00
abstract::A basic medical director function is to help draft and implement policies and procedures. Physicians should not underestimate the knowledge and skills involved in doing it well. Instead of viewing this role as merely unpleasant paper work, they should look beneath the surface for the much broader implications. Effecti...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::Syncope is a common clinical problem accounting for 3% of all emergency room visits and 1% to 6% of all hospital admissions. Both a sign and a symptom, syncope can be caused by a wide variety of conditions. Syncope in the geriatric patient can be a particularly challenging problem because of the coexistence of multipl...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2012.07.002
更新日期:2012-11-01 00:00:00
abstract::The treatment of nonpain symptoms is integral to good palliative care of the terminally ill elder. This article reviews the management of common physical symptoms observed during the dying process, including nausea and vomiting, dyspnea, cough, constipation, diarrhea, bowel obstruction, and xerostomia. Alleviation of ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1996-05-01 00:00:00
abstract::Falls are a major health concern for elderly people and cause substantial health care costs. The authors used meta-analytic findings on the effectiveness of fall prevention interventions to determine cost-effectiveness of a proposed Medicare fall prevention program for people who experience a recent fall. Using publis...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.cger.2010.07.005
更新日期:2010-11-01 00:00:00
abstract::An analysis of the risk factors and clinical presentation of intracerebral hemorrhage in the elderly is provided. Specific pathogenic mechanisms that apply to the elderly, such as cerebral amyloid angiopathy, are discussed in detail. General management of intracerebral hemorrhage is discussed, along with specific issu...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1991-08-01 00:00:00
abstract::"Birth and death are the most singular events we experience and therefore the contemplation of death as of birth should be a thing of beauty." The hospice movement emerged out of an awareness that the needs of the dying patient were not being adequately met by the modern medical establishment. It has brought about a p...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1986-08-01 00:00:00
abstract::Aspirin in a dose of 160 to 325 mg should be administered on day 1 of an acute MI and continued indefinitely on a daily basis. Thrombolytic therapy should be administered within 6 to 12 hours after the onset of an acute MI with ST segment elevation or with left bundle branch block. Primary coronary angioplasty when av...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(05)70113-0
更新日期:2001-02-01 00:00:00
abstract::Quality of life is becoming increasingly important in assessing the impact of therapy for hypertension in elderly persons. Although the concept of quality of life is new and is in need of further definition, good measures already exist to examine the effects of therapy in the major domains of quality of life such as s...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-11-01 00:00:00
abstract::Epidemiological data suggests that the prevalence of musculoskeletal and neuropathic pain increases with age until at least late mid-life, though the pattern is somewhat unclear beyond this point. And though the prevalence of some types of pain may peak in late midlife, pain is still a substantial and common complaint...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2016.06.005
更新日期:2016-11-01 00:00:00
abstract::Although many individuals who have had strokes or other physical problems assume that they can no longer drive, they are often unaware of retraining programs. In addition to formal courses supported by sponsoring agencies, such as the AAA, there are also programs run by occupational therapists. This article addresses ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1993-05-01 00:00:00
abstract::Chest pain is one of the most common and serious chief complaints. Geriatricians must be well versed in evaluating elderly patients who have chest pain. This article discusses the initial diagnostic evaluation of elderly patients with chest pain. Specific emphasis is placed on identifying acute coronary syndromes, aor...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2007.01.005
更新日期:2007-05-01 00:00:00
abstract::Most diseases involving the skin affect all age groups; however, some are more common in old age. The skin of the genital area may be involved as an isolated process or as part of more generalized disease. Clinical features and management of some of the more common dermatologic conditions affecting the genital area in...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1990-02-01 00:00:00
abstract::The importance of education in preventing and treating patients with pressure ulcers is evident by the inclusion of recommendations for educational objectives in the clinical guidelines by the Agency for Health Care Policy and Research. Both caregiver and client should be assessed for knowledge of pressure ulcers. Phy...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1997-08-01 00:00:00
abstract::Cancer screening of the elderly is warranted for those cancers for which early detection and treatment improve life expectancy. There is excellent evidence to include screening for breast cancer with clinical examination and mammography for elderly women. There is also reasonable evidence to screen for cervical cancer...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract::The number of people in nursing homes is growing at a rapid rate as the population includes greater numbers of elderly Americans. Psychiatric disorders, including depression, anxiety, and paranoia, are commonly seen among this group. Recognition and treatment of these disorders by health care professionals can improve...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1988-08-01 00:00:00
abstract::Research has conclusively established that normal diploid cells in culture have a limited replicative life span, and that cells from adult organisms have a shorter life span than cells from young organisms or embryos. Although it is unlikely that death of the organism is caused by failure in cellular proliferative cap...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-02-01 00:00:00
abstract::Hip surgery is the most common major orthopedic procedure performed in the elderly. The indications are fracture and pain secondary to degenerative arthritis. Patients undergoing hip replacement for arthritis have excellent outcomes with decreased pain, increased mobility, and a low mortality. Age should not be a cont...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1990-08-01 00:00:00
abstract::Colorectal cancer is one of the leading causes of death in older men and women. Therefore, this age-related cancer is of particular importance to geriatricians. The high incidence of this cancer may be decreased by dietary modifications recommended by the American Cancer Society. Early cancer detection is important to...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1987-11-01 00:00:00
abstract::Approximately 35% to 37% of older emergency department (ED) patients will have delirium or dementia, which can negatively affect safe and appropriate clinical care. This article describes the epidemiology of delirium and dementia in the ED and how it affects clinical care and patient outcomes. Screening for delirium a...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2018.05.001
更新日期:2018-08-01 00:00:00
abstract::Behavioral signs and symptoms in dementia are common, morbid, classifiable, and treatable. The current state-of-the-art approach is to evaluate carefully for social or environmental causes, intercurrent medical conditions, or other triggers of the behavior and attempt to deal with those directly. When these conservati...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(05)70073-2
更新日期:2001-05-01 00:00:00
abstract::Osteoarthritis (OA) is the most common cause of chronic disability in older adults. Although classically considered a "wear and tear" degenerative condition of articular joints, recent studies have demonstrated an inflammatory component to OA that includes increased activity of several cytokines and chemokines in join...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2010.03.002
更新日期:2010-08-01 00:00:00
abstract::Geriatric hip fracture is a common event associated with high costs of care and often with suboptimal outcomes for the patients. Ideally, a new care model to manage geriatric hip fractures would address both quality and safety of patient care as well as the need for reduced costs of care. The geriatric fracture center...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2014.01.002
更新日期:2014-05-01 00:00:00
abstract::Both primary and secondary cancer prevention may improve cancer control among older persons. Although chemoprevention of cancer is feasible, the agents currently used for chemoprevention have several complications. As a result, the use of these substances should be individualized based on risk-benefit ratio. It is rea...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/s0749-0690(02)00028-9
更新日期:2002-08-01 00:00:00
abstract::Elderly individuals not only live longer but are also more active than in the past. Accompanying this increase in activity is the number of older trauma victims. The effect of aging on response to injury is reviewed, and the initial evaluation and treatment of geriatric trauma are delineated in this article. Specific ...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1993-08-01 00:00:00
abstract::Urinary incontinence (UI) in the older adult is a multisystem health problem that has an impact on the lives of millions of older adults. Advanced practice nurses (APNs) specializing in gerontology,family, and adult practice are equipped educationally with the expertise to prevent, assess, and manage this health probl...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2004.04.015
更新日期:2004-08-01 00:00:00
abstract::Patients often present for evaluation of a suspicious cancer symptom after a delay. They appear to tolerate cancer treatment as well as younger patients, and, in studies comparing them on psychosocial parameters of adaptation, they appear to adjust better than younger patients. Attention to pre-existing social problem...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:
更新日期:1987-08-01 00:00:00
abstract::Healthy aging is a process that occurs over the life cycle. Health habits established early and practiced throughout life impact longevity, the ability to reach old age, and the health with which one experiences older adulthood. The new field of lifestyle medicine addresses root causes of disease by targeting nutritio...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cger.2020.06.007
更新日期:2020-11-01 00:00:00
abstract::The definition of sarcopenia continues to evolve, from an observational phenomenon to a differential diagnostic approach. Clinical relevance for sarcopenia is defined by a loss in lean muscle mass and impairment of functional status. A therapeutic approach to the loss of skeletal muscle mass and strength in older pers...
journal_title:Clinics in geriatric medicine
pub_type: 杂志文章
doi:10.1016/j.cger.2010.02.012
更新日期:2010-05-01 00:00:00