Abstract:
:A monoclonal antibody raised by immunization of BALB/c mice with erythrocytic stages of Plasmodium vivax was shown to react with asexual erythrocytic stages of P. chabaudi. The cross-reactivity molecules are antigens of 200 and 148 kDa in P. vivax and of 190 and 70 kDa in P. chabaudi. Immunofluorescence studies of the erythrocytic stages of P. vivax and P. chabaudi indicated that expression of these antigens increased as the parasites' developed from the ring stage to the schizont stage. In the mature trophozoites of P. chabaudi, immunoelectron microscopy revealed clusters of antigen distributed in the cytoplasm of the parasitized erythrocyte. In the schizont, packets of antigen were found associated with the parasitophorous vacuole and the cytoplasm of the infected host cell.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Perez HA,Bracho C,Romano M,De la Rosa Mdoi
10.1007/s004360050241subject
Has Abstractpub_date
1997-01-01 00:00:00pages
246-51issue
3eissn
0932-0113issn
1432-1955journal_volume
83pub_type
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