Plasmodium vivax and P. chabaudi: inter-species cross-reacting antigens.

Abstract:

:A monoclonal antibody raised by immunization of BALB/c mice with erythrocytic stages of Plasmodium vivax was shown to react with asexual erythrocytic stages of P. chabaudi. The cross-reactivity molecules are antigens of 200 and 148 kDa in P. vivax and of 190 and 70 kDa in P. chabaudi. Immunofluorescence studies of the erythrocytic stages of P. vivax and P. chabaudi indicated that expression of these antigens increased as the parasites' developed from the ring stage to the schizont stage. In the mature trophozoites of P. chabaudi, immunoelectron microscopy revealed clusters of antigen distributed in the cytoplasm of the parasitized erythrocyte. In the schizont, packets of antigen were found associated with the parasitophorous vacuole and the cytoplasm of the infected host cell.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Perez HA,Bracho C,Romano M,De la Rosa M

doi

10.1007/s004360050241

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

246-51

issue

3

eissn

0932-0113

issn

1432-1955

journal_volume

83

pub_type

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