Abstract：
BACKGROUND:In this study of laparoscopic splenectomy (LS), we evaluate prospectively gathered perioperative patient data and review lessons learned in the evolution of this procedure. METHODS:At 2 university medical centers between November 1993 and March 2000, there were 203 patients (122 female patients and 81 male patients) who underwent LS after preoperative evaluation. RESULTS:LS was successfully completed in 197 patients (97%). The mean operative time was 145.5 minutes and the length of stay averaged 2.7 days with 143 (70.4%) staying less than 48 hours. The most common indication was idiopathic thrombocytopenic purpura (ITP). Six patients required conversion to open splenectomy (OS), with only 2 conversions in the last 163 cases. No deaths were attributed to the procedure. Complications occurred in 19 patients (9.3%). Thirty accessory spleens were identified in 25 patients (12.3%). Seventeen patients (8.4%) underwent concomitant procedures, most commonly cholecystectomy. CONCLUSIONS:LS by the lateral approach is both safe and feasible in patients of all ages.
journal_name
Surgeryjournal_title
Surgeryauthors
Park AE,Birgisson G,Mastrangelo MJ,Marcaccio MJ,Witzke DBdoi
10.1067/msy.2000.109065subject
Has Abstractpub_date
2000-10-01 00:00:00pages
660-7issue
4eissn
0039-6060issn
1532-7361pii
S0039-6060(00)67915-1journal_volume
128pub_type
临床试验,杂志文章,多中心研究相关文献
SURGERY文献大全abstract：BACKGROUND:With tighter constraints on health care spending, many recognize the need to identify and restrict clinical interventions that are not cost-effective. As a result, cost-effectiveness analysis is being used increasingly to assess the relative value of surgical interventions. METHODS AND RESULTS:We first pres...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:We determined whether hepatic intra-arterial infusion of 5-fluorouracil (5-FU) in patients with synchronous hepatic metastases from colorectal cancer, in whom the primary lesion was resectable but hepatic metastatic lesions were non-resectable helped improve survival time when administered on the basis of the...
journal_title：Surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.surg.2006.03.001
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Gender differences have been noted in acute ischemia/reperfusion injury. Estrogen and the estrogen receptors (ER) appear to play a critical role in cardiovascular gender differences, given that females have improved myocardial functional recovery associated with decreased tissue inflammation. It has been sug...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.03.009
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:The recent development of stereoscopic images using 3-dimensional monitors is expected to improve techniques for laparoscopic operation. Several studies have reported technical advantages in using 3-dimensional monitors with regard to operative accuracy and working speed, but there are few reports that analy...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.08.060
更新日期：2017-05-01 00:00:00
abstract：:The immune response to an intravenous bolus of sheep erythrocytes, a large particulate antigen, was examined in weanling Sprague-Dawley rats after varying reduction in spleen size by splenic artery ligation (SAL) or partial amputation (pSx), and the results were compared with splenectomized (Sx) and sham-operated cont...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：BACKGROUND:Longitudinal, risk-adjusted measurement of outcomes of carotid artery (CA) surgery is necessary for the evaluation of quality performance and for the assessment of strategies of quality improvement. METHODS:Patients from quality coding hospitals who underwent CA surgery and met procedural and diagnostic cod...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2015.06.005
更新日期：2015-10-01 00:00:00
abstract：:Two patients were treated for asymptomatic aneurysms of the inferior mesenteric artery during reconstructive operation for infrarenal aortic disease. These lesions were discovered incidentally during arteriographic study in one case and during operation in the second case. Including these two patients, the number of r...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1985-02-01 00:00:00
abstract：:Hypothermia to less than 30 degrees C is associated with significant harmful effects, including ventricular fibrillation. None of the currently used techniques for core rewarming is entirely satisfactory. Continuous perfusion of the pleural space with warm saline solution has been studied as a method of core rewarming...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：BACKGROUND:Our aim was to examine the outcomes of patients with tertiary hyperparathyroidism (3-HPT) who had limited resection of 1 or 2 parathyroids. METHODS:We reviewed 140 patients with 3-HPT who underwent parathyroidectomy (PTX) at a single institution. Patients were analyzed according to their operation-limited P...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2009.09.026
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Previously we demonstrated that optimal doses of tumor-infiltrating lymphocytes (TIL) concomitant with recombinant interleukin-2 (rIL-2) effectively mediated complete tumor regression of murine 3-day pulmonary metastases. METHODS:In the present study we have investigated the contribution of the host immune ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(05)80209-0
更新日期：1995-03-01 00:00:00
abstract：:Aspiration devices can persistently malfunction if moderate (not just high) suction causes mucosal occlusion of every opening. The standard pattern of uniformly large orifices was modified by supplementing half the nasal tubes with smaller (one tenth of the area) openings. Ten pairs of postoperative patients sipped wa...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:Clinical investigations in patients who have undergone transplantation and patients with cancer and infection suggest that blood transfusions have an immunosuppressive effect. To investigate the impact on responses to infection, an experimental transfusion model was developed in the rat with allogeneic or syngeneic tr...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
abstract：BACKGROUND:Vascular endothelial growth factor-D (VEGF-D), the activating ligand for vascular endothelial growth factor receptor-3 (VEGFR-3), has been identified as an important endogenic tumor-associated lymphangiogenic factors which can promote lymphatic metastasis from primary tumor. Lymphatic metastasis, which is th...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2009.04.025
更新日期：2009-11-01 00:00:00
abstract：:Nelson's syndrome--progressive cutaneous hyperpigmentation with x-ray film evidence of an expanding pituitary tumor--is now a well-recognized sequela of bilateral adrenalectomy for Cushing's disease. It is estimated to occur in 8% to 38% of adults. Because Cushing's disease is rare in children, a higher incidence of N...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-12-01 00:00:00
abstract：:To evaluate its clinical benefit in adults, herniography was used in 73 patients with clinically unexplained groin pain. Hernias were demonstrated on the side with symptoms in 26 patients (36%). Relief of groin pain was registered in 16 of 17 patients who subsequently underwent operation. We consider herniography to b...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:Eleven parathyroid cysts were found in 325 patients who underwent parathyroid operations. Ten cysts were located in the neck and one was located in the mediastinum. The cysts ranged in size from 1.6 to 10 cm with a mean of 3.9 cm. The patients who had cysts included six women and five men, and their ages ranged from 2...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to elucidate the mechanism of reduced intestinal transit rate in the ileum as compared with the jejunum. METHODS:Twenty-one dogs were each instrumented with 12 strain gauge transducers, 2 collection cannulas, and an infusion catheter defining a 100 cm study in the midjejunum (n...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(97)90288-9
更新日期：1997-02-01 00:00:00
abstract：:The multiple endocrine neoplasia (MEN) IIb syndrome has been differentiated from MEN IIa by the presence of various phenotypic characteristics such as mucosal neuromas, marfanoid habitus, congenital skeletal anomalies, and prominent corneal nerves, as well as the lack of parathyroid involvement. Analysis of a kindred ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：BACKGROUND:The presence or absence of lymph node metastases is known to be an important prognostic factor for patients with pancreatic cancer. Few studies have investigated the ratio of the number of lymph nodes harboring metastatic cancer to the total number of lymph nodes examined (lymph node ratio [LNR]) with regard...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2006.12.013
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:In sepsis red blood cells (RBCs) have been shown to be less deformable (i.e., more rigid) and have been implicated in decreasing nutrient blood supply and possibly leading to organ dysfunction. However, no studies have demonstrated an association between organ dysfunction and rigid RBCs. This study examined ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:Ischemia and reperfusion lead to eicosanoid- and neutrophil (PMN)-dependent injury. This study tests the role of ischemia-induced lipoxygenase activity in mediating PMN activation and diapedesis. Anesthetized rabbits (n = 8) underwent 3 hours of bilateral hindlimb ischemia. At 10 minutes of reperfusion, leukotriene B4...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:Corticosteroid use continues to rise nationally. Studies have evaluated the impact of chronic steroid use on surgical outcomes in smaller populations. This study investigated the impact of chronic steroid use on perioperative surgical outcomes in a surgical cohort of more than 5 million surgical patients, us...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2018.12.016
更新日期：2019-05-01 00:00:00
abstract：:Serial determinations of human thymus-dependent (T) and bone marrow-dependent (B) peripheral blood lymphocytes were performed to detect changes in activity of these rosette-forming cells in five groups of patients: controls; chronic renal failure (CRF) patients; dialysis patients receiving pretransplant splenectomy; 5...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-04-01 00:00:00
abstract：BACKGROUND:The aims of the present study were to confirm the consumption coagulopathy of disseminated intravascular coagulation with the fibrinolytic phenotype at an early phase of trauma and to test the hypothesis that thrombin-activatable fibrinolysis inhibitor, neutrophil elastase, and plasmin contribute to the incr...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2010.06.010
更新日期：2011-02-01 00:00:00
abstract：INTRODUCTION:Laparoscopic adrenalectomy (LA) is a safe minimally invasive approach for treatment of pheochromocytoma (PHEO). Posterior retroperitoneoscopic adrenalectomy (PRA) is an alternative minimally invasive technique; however, there is a lack of data regarding the appropriateness of this approach in patients with...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2011.07.004
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:We hypothesized that acetylation of the Stat1 regulates interferon-gamma (IFN-gamma) mediated macrophage expression of inducible nitric oxide synthase (iNOS). METHODS:RAW 264.7 iNOS expression was induced with IFN-gamma. Deacetylase inhibitors trichostatin A (TSA) or valproic acid (VPA) were added. Stat1 an...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2007.02.016
更新日期：2007-08-01 00:00:00
abstract：INTRODUCTION:We hypothesized that most contralateral breast cancers (CBCs) develop ≥5 years after the primary breast cancer (PBC) and that CBCs have more favorable tumor characteristics. METHODS:This is a single-institution retrospective review of 323 patients who were diagnosed with CBC from 1990 to 2014. CBCs were d...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2015.03.059
更新日期：2015-09-01 00:00:00
abstract：:In this study a smooth muscle cell seeding technique was developed and evaluated in biodegradable vascular grafts in rats. Cultured smooth muscle cells (3.5 to 5 X 10(6) in 0.1 ml whole blood) were seeded by means of a one-step preclotting technique in microporous, compliant, biodegradable vascular grafts (internal di...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：BACKGROUND:Although fine-needle aspiration (FNA) is 90% sensitive in the detection of papillary carcinoma (PC) of the thyroid, its specificity has been reported as low as 52%. Consequently, patients who have an FNA suspicious for PC may undergo operation for a benign process. The ribonucleoprotein telomerase has been n...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(97)90219-1
更新日期：1997-12-01 00:00:00
abstract：:Dr McCarthy is a fellow in cardiothoracic surgery at the University of Washington. During his general surgery training at Northwestern University, he completed a research fellowship in surgical innovation and obtained masters' degrees with a focus on health enterprise management, entrepreneurship, and innovation. ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.08.035
更新日期：2017-04-01 00:00:00
