Treatment of angioimmunoblastic lymphadenopathy with dysproteinemia using 2-chlorodeoxyadenosine.

abstract：:African Americans have two- to three-fold higher incidence of multiple myeloma and MGUS compared to other ethnic groups in the USA. Some physicians often perform diagnostic evaluations for plasma cell disorders (PCD) in African American patients on the basis of hematological abnormalities (thrombocytopenia, leucopenia...

journal_title：Annals of hematology

authors： Tun NM,Joseph G,Soe AM,Ford JG

更新日期：2014-06-01 00:00:00

abstract：:Extranodal natural killer/T cell lymphoma, nasal type (ENKTL) is an aggressive disease with a poor prognosis, requiring risk stratification in affected patients. We designed a new prognostic model specifically for ENKTL to identify high-risk patients who need more aggressive therapy. We retrospectively reviewed 158 pa...

journal_title：Annals of hematology

authors： Cai Q,Luo X,Zhang G,Huang H,Huang H,Lin T,Jiang W,Xia Z,Young KH

更新日期：2014-09-01 00:00:00

abstract：:We retrospectively evaluated the role of rituximab (R) in maintenance treatment after autologous stem cell transplantation performed in patients with relapsed follicular lymphoma. We compared the outcome of 67 follicular lymphoma (FL) patients according to the use of rituximab maintenance (RM) or not. All patients rec...

journal_title：Annals of hematology

authors： Bourcier J,Gastinne T,Leux C,Moreau A,Bossard C,Mahé B,Blin N,Dubruille V,Touzeau C,Voldoire M,Guillaume T,Peterlin P,Gallas P,Garnier A,Maisonneuve H,Moreau P,Juge-Morineau N,Jardel H,Chevallier P,Moreau P,Le Gou

更新日期：2016-08-01 00:00:00

abstract：:Thrombotic thrombocytopenia purpura (TTP) and atypical hemolytic uremic syndromes (aHUS) are distinct clinical disorders characterized by hemolytic anemia, thrombocytopenia, microthrombi, and end organ damage. TTP is characterized by a low ADAMTS13 activity level at diagnosis of <10 % ADAMTS13 activity, while aHUS is ...

journal_title：Annals of hematology

authors： Saultz JN,Wu HM,Cataland S

更新日期：2015-09-01 00:00:00

abstract：:Recent developments in the field of targeted therapy have led to the discovery of a new drug, plerixafor, that is a specific inhibitor of the CXCR4 receptor. Plerixafor acts in concert with granulocyte colony-stimulating factor (G-CSF) to increase the number of stem cells circulating in the peripheral blood (PB). Ther...

journal_title：Annals of hematology

authors： Basak GW,Knopinska-Posluszny W,Matuszak M,Kisiel E,Hawrylecka D,Szmigielska-Kaplon A,Urbaniak-Kujda D,Dybko J,Zielinska P,Dabrowska-Iwanicka A,Werkun J,Rzepecki P,Wroblewska W,Wiktor-Jedrzejczak W

更新日期：2011-05-01 00:00:00

abstract：:The Infectious Diseases Working Party of the German Society of Haematology and Oncology presents their guidelines for the treatment of fungal infections in patients with hematological and oncological malignancies. These guidelines are evidence-based, considering study results, case reports and expert opinions, using t...

journal_title：Annals of hematology

authors： Böhme A,Ruhnke M,Buchheidt D,Karthaus M,Einsele H,Guth S,Heussel G,Heussel CP,Junghanss C,Kern WK,Kubin T,Maschmeyer G,Sezer O,Silling G,Südhoff T,Szelényi Dagger H,Ullmann AJ,Infectious Diseases Working Party (AGIHO) o

更新日期：2003-10-01 00:00:00

abstract：:The purpose of this report is to provide long-term follow-up of 38 patients diagnosed of post-transplant lymphoproliferative disease (PTLD) included in a phase 2 clinical trial of first line therapy with rituximab and to evaluate the same therapy in a real world cohort of 21 consecutive patients treated once the trial...

journal_title：Annals of hematology

authors： González-Barca E,Capote FJ,Gómez-Codina J,Panizo C,Salar A,Sancho JM,López A,Briones J,Muñoz A,Encuentra M,Mercadal S,Domingo-Domenech E,de Sevilla AF,GELTAMO (Spanish Lymphoma Group) and GOTEL (Group of Oncology for Therapy an

更新日期：2020-05-04 00:00:00

abstract：:We recently reported that IgM antibody-related microparticles exist in some patients with idiopathic thrombocytopenic purpura (ITP) [14]. In this study, we investigated the relationship between antiphospholipid (cardiolipin and phosphatidylinositol) antibodies and microparticles in 56 ITP patients. We used an ELISA to...

journal_title：Annals of hematology

authors： Nomura S,Yanabu M,Fukuroi T,Kido H,Kawakatsu T,Yamaguchi K,Suzuki M,Kokawa T,Yasunaga K

更新日期：1992-07-01 00:00:00

abstract：:Spontaneous splenic rupture is a rare, though life-threatening complication of some hematological malignancies and is even more infrequent as the initial symptom of acute lymphoblastic leukemia. We describe the fourth case, to our knowledge, of acute lymphoblastic leukemia presenting as splenic rupture, and for the fi...

journal_title：Annals of hematology

authors： Altès A,Brunet S,Martinez C,Soler J,Ayats R,Sureda A,López R,Domingo A

更新日期：1994-03-01 00:00:00

abstract：:The general objective of this study was to evaluate the risks of agranulocytosis and aplastic anemia in relation to drug use. Other potential risk factors, including history of infectious mononucleosis, were also evaluated. In an international population-based case-control study, cases of agranulocytosis and aplastic ...

journal_title：Annals of hematology

authors： Levy M,Kelly JP,Kaufman DW,Shapiro S

更新日期：1993-10-01 00:00:00

abstract：:Since July 2017, different generic imatinib formulations have been introduced in Italy for the treatment of patients with chronic myeloid leukemia (CML). We analyzed 168 chronic phase CML patients treated with branded imatinib for a median of 12 years (range 1-16) at a single institution who switched to a single gener...

journal_title：Annals of hematology

authors： Scalzulli E,Colafigli G,Latagliata R,Pepe S,Diverio D,Stocchi F,Di Prima A,Efficace F,Martelli M,Foà R,Breccia M

更新日期：2020-12-01 00:00:00

abstract：:To assess the survival outcomes and adverse events (AEs) of high-intermediate- or high-risk patients with diffuse large B cell lymphoma (DLBCL) who underwent conventional chemotherapy plus rituximab with or without first-line autologous stem cell transplantation (ASCT). Related studies published on Medline, Embase, Co...

journal_title：Annals of hematology

authors： Ma SY,Tian XP,Cai J,Zhong GZ,Chen X,Huang HQ,Lin TY,Li ZM,Cai QQ

更新日期：2020-06-01 00:00:00

abstract：:Haplo-identical transplants (Haplo-Tx) are an important alternative for patients with hematological malignancies who lack a HLA-identical donor. Seventy-one T-replete Haplo-Tx were performed in 70 high-risk patients at our center; 22/70 (31%) patients with refractory/relapsed leukemia received sequential salvage thera...

journal_title：Annals of hematology

authors： Brunello L,Passera R,Dellacasa CM,Giaccone L,Audisio E,Ferrero D,D'Ardia S,Allione B,Aydin S,Festuccia M,Lia G,Crisà E,Maffini E,Butera S,Busca A,Bruno B

更新日期：2018-11-01 00:00:00

abstract：:Expression of long non-coding RNA KIAA0125 has been incorporated in various gene expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients, yet its functions and clinical significance remain unclear. This study aimed to investigate the clinical and biological characteristics of AML beari...

journal_title：Annals of hematology

authors： Wang YH,Lin CC,Hsu CL,Hung SY,Yao CY,Lee SH,Tsai CH,Hou HA,Chou WC,Tien HF

更新日期：2021-02-01 00:00:00

abstract：:Acquired aplastic anemia (AA) and paroxysmal nocturnal hemoglobinuria (PNH) are interrelated ultra-rare diseases. Quality of life (QoL) evaluation tools used in studies for AA and PNH are unspecific and designed for cancer patients (e.g., the European Organization for Research and Treatment of Cancer Quality of Life Q...

journal_title：Annals of hematology

authors： Groth M,Singer S,Niedeggen C,Petermann-Meyer A,Röth A,Schrezenmeier H,Höchsmann B,Brümmendorf TH,Panse J

更新日期：2017-02-01 00:00:00

abstract：:Somatic mutations in the SF3B1 gene, a gene encoding the splicing factor 3B subunit 1, were recently reported in myelodysplastic syndromes (MDS), particularly in the presence of ring sideroblasts (RS). The authors investigated the prevalence and clinical significance of SF3B1 mutations in Korean patients with myeloid ...

journal_title：Annals of hematology

authors： Seo JY,Lee KO,Kim SH,Kim K,Jung CW,Jang JH,Kim HJ

更新日期：2014-04-01 00:00:00

abstract：:To explore the clinicopathological characteristics and outcomes of light chain deposition disease (LCDD) in a Chinese population, we retrospectively studied the clinicopathological data, treatment, and outcomes of 48 patients with biopsy-proven LCDD from a single center. Among the patients, there were 29 males and 19 ...

journal_title：Annals of hematology

authors： Li XM,Rui HC,Liang DD,Xu F,Liang SS,Zhu XD,Huang XH,Liu ZH,Zeng CH

更新日期：2016-05-01 00:00:00

abstract：:We retrospectively analyzed overall survival and survival after progression in 91 patients with low-grade follicular lymphoma (LGFL). Histological subtype was B in 75 patients and C in 16 patients. Twelve patients with localized disease received involved-field radiotherapy; seven patients without bulky disease had no ...

journal_title：Annals of hematology

authors： Morel P,Dupriez B,Plantier-Colcher I,Gosselin B,Declercq C,Pollet JP,Bauters F

更新日期：1993-06-01 00:00:00

abstract：:Eight patients who were carriers of beta-thalassemia induced by the cd121 (G-->T) mutation are described in four nonrelated Dutch families. This mutant, which is considered rare and inherited in a dominant manner, is expressed in a different way among each of the four families and even among carriers of the same famil...

journal_title：Annals of hematology

authors： Giordano PC,Harteveld CL,Michiels JJ,Terpstra W,Schelfhout LJ,Appel IM,Batelaan D,van Delft P,Plug RJ,Bernini LF

更新日期：1998-12-01 00:00:00

abstract：:Follicular lymphoma (FL) is an indolent non-Hodgkin's lymphoma with heterogeneous outcomes. Progression or relapse of FL within 2 years (so-called POD24) after diagnosis is associated with a poor outcome for patients treated with R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, prednisone) in clinica...

journal_title：Annals of hematology

authors： Sortais C,Lok A,Tessoulin B,Gastinne T,Mahé B,Dubruille V,Blin N,Touzeau C,Moreau A,Bossard C,Peterlin P,Garnier A,Guillaume T,Le Bourgeois A,Chevallier P,Moreau P,Leux C,Le Gouill S

更新日期：2020-07-01 00:00:00

abstract：:A 4-day colorimetric tetrazolium dye (MTT) assay was used to assess the cytotoxicity of adriamycin (ADM), vincristine (VCR), and idarubicin (IDA) in blasts isolated from 37 patients with newly diagnosed and pretreated acute myeloid leukemia (AML). The effect of verapamil (VRP) as a chemosensitizer was studied in relat...

journal_title：Annals of hematology

authors： Müller MR,Lennartz K,Boogen C,Nowrousian MR,Rajewsky MF,Seeber S

更新日期：1992-11-01 00:00:00

abstract：:Rituximab was recently described also as first-line therapy of chronic graft-versus-host disease (cGvHD). We retrospectively analyzed the efficacy and safety of all patients receiving rituximab for treatment of cGvHD between 2005 and 2016 at the Regensburg University transplant center with a median follow-up after rit...

journal_title：Annals of hematology

authors： Klobuch S,Weber D,Holler B,Edinger M,Herr W,Holler E,Wolff D

更新日期：2019-10-01 00:00:00

abstract：:Burkitt lymphoma (BL) is an aggressive B-cell lymphoma more common in children comprising one third of pediatric non-Hodgkin lymphoma cases. The recent discovery in BL pathogenesis highlighted the activation of PI3K pathway in cooperation with Myc in the development of BL. In this study, we demonstrated that PI3K/Akt ...

journal_title：Annals of hematology

authors： Ferreira AC,Robaina MC,Rezende LM,Severino P,Klumb CE

更新日期：2014-06-01 00:00:00

abstract：:We integrated molecular data with available prognostic factors in patients undergoing allogeneic hematopoietic cell transplantation (alloHCT) for myelodysplastic syndrome (MDS) or secondary acute myeloid leukemia (sAML) from MDS to evaluate their impact on prognosis. Three hundred four patients were sequenced for muta...

journal_title：Annals of hematology

authors： Heuser M,Gabdoulline R,Löffeld P,Dobbernack V,Kreimeyer H,Pankratz M,Flintrop M,Liebich A,Klesse S,Panagiota V,Stadler M,Wichmann M,Shahswar R,Platzbecker U,Thiede C,Schroeder T,Kobbe G,Geffers R,Schlegelberger B,Gö

更新日期：2017-08-01 00:00:00

abstract：:Rituximab induces B-cell depletion; therefore, it has been used in the treatment of immune thrombocytopenic purpura (ITP). The aim of this retrospective study was to evaluate the effectiveness of rituximab in the treatment of 89 patients with chronic ITP refractory to several treatments. All the patients had platelet ...

journal_title：Annals of hematology

authors： Peñalver FJ,Jiménez-Yuste V,Almagro M,Alvarez-Larrán A,Rodríguez L,Casado M,Gallur L,Giraldo P,Hernández R,Menor D,Rodríguez MJ,Caballero D,González R,Mayans J,Millán I,Cabrera JR,Multi-institutional Retrospective Spanish

更新日期：2006-06-01 00:00:00

abstract：:2-Chlorodeoxyadenosine (2-CdA) is a purine analogue which has proved to be active in acute myeloid leukemia (AML), especially in children. In adults, results yielded by 2-CdA alone or with ara-C were less encouraging. Here we report on the efficacy of 2-CdA with or without daunorubicin (DNR) in 19 relapsing or refract...

journal_title：Annals of hematology

authors： Van Den Neste E,Martiat P,Mineur P,Delannoy A,Doyen C,Zenebergh A,Michaux JL,Ferrant A

更新日期：1998-01-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a hematologic disorder which is clinically characterized by thrombocytopenia, microangiopathic hemolytic anemia, fever, neurologic symptoms, and cardiac and renal involvement. The pathogenic mechanisms of this disease are poorly understood. It is well known that TTP is asso...

journal_title：Annals of hematology

authors： Rozdzinski E,Hertenstein B,Schmeiser T,Seifried E,Kurrle E,Heimpel H

更新日期：1992-05-01 00:00:00

abstract：:Chronic idiopathic neutropenia of adults (CINA) is a granulocytic disorder characterised by the "unexplained" decrease in the number of circulating neutrophils. Serum inflammatory cytokines and chemokines are increased in CINA. In addition, cytokines gene polymorphisms are associated with increased levels of respectiv...

journal_title：Annals of hematology

authors： Addas-Carvalho M,de Paula EV,Lima CS,Saad ST

更新日期：2005-10-01 00:00:00

abstract：:Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPN) comprise a heterogeneous group of chronic hematologic malignancies. The quality of life, morbidity, and mortality of patients with MPN are primarily affected by disease-related symptoms, thromboembolic and hemorrhagic complications, and progression t...

journal_title：Annals of hematology

authors： Appelmann I,Kreher S,Parmentier S,Wolf HH,Bisping G,Kirschner M,Bergmann F,Schilling K,Brümmendorf TH,Petrides PE,Tiede A,Matzdorff A,Griesshammer M,Riess H,Koschmieder S

更新日期：2016-04-01 00:00:00

abstract：:Pre-engraftment syndrome (PES) is a condition occurring after umbilical cord blood transplantation (UCBT) characterized by fever and erythematous skin rash prior to neutrophil engraftment. We sought to determine the incidence and characterize the pulmonary manifestations of PES. A retrospective review of patients who ...

journal_title：Annals of hematology

authors： Brownback KR,Simpson SQ,McGuirk JP,Lin TL,Abhyankar S,Ganguly S,Aljitawi OS

更新日期：2014-05-01 00:00:00