Cystic fibrosis diagnosed after age 13. Twenty-five teenage and adult patients including three asymptomatic men.

abstract：STUDY OBJECTIVE:To determine the usefulness of the continuous intravenous dexamethasone suppression test in the differential diagnosis of patients with the Cushing syndrome. DESIGN:Comparison of the results of this test with those of other tests in the study population and with data from the literature. SETTING:Refer...

journal_title：Annals of internal medicine

authors： Biemond P,de Jong FH,Lamberts SW

更新日期：1990-05-15 00:00:00

abstract：PURPOSE:To develop a clinical perspective on bilateral massive adrenal hemorrhage and an algorithm for its diagnosis and treatment. DATA IDENTIFICATION:Case reports were identified through a computer search using MEDLIN (1976 to 1987), and from bibliographies in review articles (up to 1978). STUDY SELECTION:Twelve re...

journal_title：Annals of internal medicine

authors： Rao RH,Vagnucci AH,Amico JA

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Soon, half of all physicians may be married to other physicians (that is, in dual-doctor families). Little is known about how marriage to another physician affects physicians themselves. OBJECTIVE:To learn how physicians in dual-doctor families differ from other physicians in their professional and family l...

journal_title：Annals of internal medicine

authors： Sobecks NW,Justice AC,Hinze S,Chirayath HT,Lasek RJ,Chren MM,Aucott J,Juknialis B,Fortinsky R,Youngner S,Landefeld CS

更新日期：1999-02-16 00:00:00

abstract：:Large-scale, epidemic transmission of tuberculosis to patients, nonprofessional staff, nurses, and physicians has been documented recently in hospitals, clinics, acquired immunodeficiency syndrome (AIDS) residencies, and correctional facilities. Prominent factors in these outbreaks have included human immunodeficiency...

journal_title：Annals of internal medicine

authors： Iseman MD

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors slow renal disease progression and reduce cardiac morbidity and mortality in patients with diabetes. Patients' out-of-pocket costs pose a barrier to using this effective therapy. OBJECTIVE:To estimate the cost-effectiveness to Medicare of first-dollar coverage ...

journal_title：Annals of internal medicine

authors： Rosen AB,Hamel MB,Weinstein MC,Cutler DM,Fendrick AM,Vijan S

更新日期：2005-07-19 00:00:00

abstract：BACKGROUND:In previous open-label noncomparative clinical trials, both fluconazole and itraconazole were effective therapy for progressive forms of coccidioidomycosis. OBJECTIVE:To determine whether fluconazole or itraconazole is superior for treatment of nonmeningeal progressive coccidioidal infections. DESIGN:Rando...

journal_title：Annals of internal medicine

authors： Galgiani JN,Catanzaro A,Cloud GA,Johnson RH,Williams PL,Mirels LF,Nassar F,Lutz JE,Stevens DA,Sharkey PK,Singh VR,Larsen RA,Delgado KL,Flanigan C,Rinaldi MG

更新日期：2000-11-07 00:00:00

abstract：:Clinicians can use data to improve daily clinical practice. This paper offers eight principles for using data to support improvement in busy clinical settings: 1) seek usefulness, not perfection, in the measurement; 2) use a balanced set of process, outcome, and cost measures; 3) keep measurement simple (think big, bu...

journal_title：Annals of internal medicine

authors： Nelson EC,Splaine ME,Batalden PB,Plume SK

更新日期：1998-03-15 00:00:00

abstract：:The second National Health and Nutrition Examination Survey found that 26% of U.S. adults, or about 34 million people aged 20 to 75 years, are overweight. The survey used a body mass index of 27.8 kg/m2 or greater for men and 27.3 or greater for women to define overweight. Prevalence of overweight increases with advan...

journal_title：Annals of internal medicine

authors： Van Itallie TB

更新日期：1985-12-01 00:00:00

abstract：:A group of 44 homosexual patients with immune thrombocytopenia and serologic evidence of infection with the human immunodeficiency virus (HIV) was observed for a total of 844 person-months. The risk of developing the acquired immunodeficiency syndrome (AIDS), an actuarial incidence of 36.5% in 37 months, was no differ...

journal_title：Annals of internal medicine

authors： Holzman RS,Walsh CM,Karpatkin S

更新日期：1987-03-01 00:00:00

abstract：:Impairment of penicillin G excretion in renal failure may result in life-threatening, dose-related toxicity. We report a method for achieving a desired mean serum penicillin G concentration in patients with renal failure, with minimal risk of both undertreatment and drug toxicity. The method is based on the linear rel...

journal_title：Annals of internal medicine

authors： Bryan CS,Stone WJ

更新日期：1975-02-01 00:00:00

abstract：:Tissues from guinea pigs inoculated intraperitoneally with the Legionnaires' disease (LD) bacterium were studied with light, immunofluorescent, and electron microscopy. The principal gross lesion was diffuse peritonitis of varying severity. Microscopically, the peritonitis of covered by a mixed inflammatory infiltrate...

journal_title：Annals of internal medicine

authors： Chandler FW,McDade JE,Hicklin MD,Blackmon JA,Thomason BM,Ewing EP Jr

更新日期：1979-04-01 00:00:00

abstract：:This following statement updates all previous recommendations on use of immune globulins for protection against viral hepatitis and use of hepatitis B vaccine and hepatitis B immune globulin for prophylaxis of hepatitis B. Recommendations cover hepatitis A; hepatitis B; non-A, non-B hepatitis; and delta hepatitis. Spe...

journal_title：Annals of internal medicine

authors：

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Four months of rifampin treatment for latent tuberculosis infection is safer, has superior treatment completion rates, and is as effective as 9 months of isoniazid. However, daily medication costs are higher for a 4-month rifampin regimen than a 9-month isoniazid regimen. OBJECTIVE:To compare health care us...

journal_title：Annals of internal medicine

authors： Bastos ML,Campbell JR,Oxlade O,Adjobimey M,Trajman A,Ruslami R,Kim HJ,Baah JO,Toelle BG,Long R,Hoeppner V,Elwood K,Al-Jahdali H,Apriani L,Benedetti A,Schwartzman K,Menzies D

更新日期：2020-08-04 00:00:00

abstract：:Five patients with chronic renal failure who were undergoing maintenance hemodialysis developed a self-limited bullous dermatosis restricted to light exposed areas, primarily involving the dorsa of the hands. Porphyrin levels and phototesting were normal, but histologic sections of the bullae showed thickening of venu...

journal_title：Annals of internal medicine

authors： Gilchrest B,Rowe JW,Mihm MC Jr

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Risk for transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to close contacts of infected persons has not been well estimated. OBJECTIVE:To evaluate the risk for transmission of SARS-CoV-2 to close contacts in different settings. DESIGN:Prospective cohort study. SETTING:Close con...

journal_title：Annals of internal medicine

authors： Luo L,Liu D,Liao X,Wu X,Jing Q,Zheng J,Liu F,Yang S,Bi H,Li Z,Liu J,Song W,Zhu W,Wang Z,Zhang X,Huang Q,Chen P,Liu H,Cheng X,Cai M,Yang P,Yang X,Han Z,Tang J,Ma Y,Mao C

更新日期：2020-12-01 00:00:00

abstract：:Nine of 81 members of two families were found to have renal problems. Three patients in one family had renal-retinal dysplasia with probable recessive inheritance. Of the 6 patients in the second family, one received a kidney transplant from his brother who initially had no detectable renal abnormality but later devel...

journal_title：Annals of internal medicine

authors： Avasthi PS,Erickson DG,Gardner KD

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Health care-associated infections from invasive medical devices in the intensive care unit (ICU) are a major threat to patient safety. Most published studies of ICU-acquired infections have come from industrialized western countries. In a Centers for Disease Control and Prevention (CDC) National Nosocomial I...

journal_title：Annals of internal medicine

authors： Rosenthal VD,Maki DG,Salomao R,Moreno CA,Mehta Y,Higuera F,Cuellar LE,Arikan OA,Abouqal R,Leblebicioglu H,International Nosocomial Infection Control Consortium.

更新日期：2006-10-17 00:00:00

abstract：:Hepatocellular carcinoma is the most frequent cancer worldwide, responsible for approximately 1,000,000 deaths annually, most of them in the Far East and in sub-Saharan Africa. It usually presents at an advanced stage and has a poor prognosis. There is evidence of an etiologic role for hepatitis B virus infection in t...

journal_title：Annals of internal medicine

authors： Di Bisceglie AM,Rustgi VK,Hoofnagle JH,Dusheiko GM,Lotze MT

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the amount of variation in in-hospital mortality and length of intensive care unit (ICU) stay that can be accounted for by clinical data available at ICU admission. DESIGN:Inception cohort study. SETTING:Forty-two ICUs in 40 hospitals, including 26 hospitals that were randomly selected and 14 la...

journal_title：Annals of internal medicine

authors： Knaus WA,Wagner DP,Zimmerman JE,Draper EA

更新日期：1993-05-15 00:00:00

abstract：:The youthful habits and family attitudes of medical students who later developed or died from one of five disease states were different from those of healthy classmate controls to begin with. In medical school, the total disorder group had significantly more nervous tension, anxiety, and anger under stress, had more i...

journal_title：Annals of internal medicine

authors： Thomas CB

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Women treated with therapeutic chest radiation may develop breast cancer. PURPOSE:To summarize breast cancer risk and breast cancer surveillance in women after chest radiation for pediatric or young adult cancer. DATA SOURCES:Studies from MEDLINE, EMBASE, the Cochrane Library, and CINAHL (1966 to December ...

journal_title：Annals of internal medicine

authors： Henderson TO,Amsterdam A,Bhatia S,Hudson MM,Meadows AT,Neglia JP,Diller LR,Constine LS,Smith RA,Mahoney MC,Morris EA,Montgomery LL,Landier W,Smith SM,Robison LL,Oeffinger KC

更新日期：2010-04-06 00:00:00

abstract：:Increased adrenocorticotropic hormone (ACTH) levels after bilateral adrenalectomy could be secondary to a pituitary tumor, under replacement with cortisol, or an abnormality in the hypothalamic-pituitary-adrenal feedback loop. To distinguish between these possibilities, ACTH levels were measured before and after corti...

journal_title：Annals of internal medicine

authors： Koletsky RJ,Dluhy RG,Crantz FR,Williams GH

更新日期：1982-03-01 00:00:00

abstract：SOURCE CITATION:Liu J, Li L, Li S, et al. Sodium-glucose co-transporter-2 inhibitors and the risk of diabetic ketoacidosis in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Diabetes Obes Metab. 2020;22:1619-27. 32364674. ...

journal_title：Annals of internal medicine

authors： Griffin TP,Dinneen SF

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:The risk for hypertension after kidney donation remains uncertain. PURPOSE:To see whether normotensive adults who donate a kidney develop higher blood pressure and risk for hypertension compared with nondonor adults acting as control participants. DATA SOURCES:MEDLINE, EMBASE, and Science Citation Index we...

journal_title：Annals of internal medicine

authors： Boudville N,Prasad GV,Knoll G,Muirhead N,Thiessen-Philbrook H,Yang RC,Rosas-Arellano MP,Housawi A,Garg AX,Donor Nephrectomy Outcomes Research (DONOR) Network.

更新日期：2006-08-01 00:00:00

abstract：:Behavioral economics provides insights about the development of effective incentives for physicians to deliver high-value care. It suggests that the structure and delivery of incentives can shape behavior, as can thoughtful design of the decision-making environment. This article discusses several principles of behavio...

journal_title：Annals of internal medicine

authors： Emanuel EJ,Ubel PA,Kessler JB,Meyer G,Muller RW,Navathe AS,Patel P,Pearl R,Rosenthal MB,Sacks L,Sen AP,Sherman P,Volpp KG

更新日期：2016-01-19 00:00:00

abstract：OBJECTIVE:To compare trimethoprim-sulfamethoxazole (TMP-SMZ) and vancomycin regarding efficacy and safety in the therapy of serious Staphylococcus aureus infections. DESIGN:Randomized, double-blind comparative trial. SETTING:A tertiary-care hospital. PATIENTS:One hundred and one intravenous drug users hospitalized w...

journal_title：Annals of internal medicine

authors： Markowitz N,Quinn EL,Saravolatz LD

更新日期：1992-09-01 00:00:00

abstract：:All practicing physicians should be prepared to respond to requests from patients for advice about participating in clinical trials research. Even physicians who choose not to conduct clinical trials but rather devote their practice to clinical care may have patients who consider volunteering for research. In advising...

journal_title：Annals of internal medicine

authors： Chen DT,Miller FG,Rosenstein DL

更新日期：2003-04-15 00:00:00

abstract：PURPOSE:To review clinical scenarios in which nonelectrophysiologist physicians may interact with patients who have implantable defibrillators. DATA SOURCES:Peer-reviewed original articles and reviews addressing aspects of implantable defibrillator therapy that are relevant to the clinician. DATA SYNTHESIS:The capaci...

journal_title：Annals of internal medicine

authors： Pinski SL,Trohman RG

更新日期：1995-05-15 00:00:00

abstract：:Treatment selection markers, sometimes called predictive markers, are factors that help clinicians select therapies that maximize good outcomes and minimize adverse outcomes for patients. Existing statistical methods for evaluating a treatment selection marker include assessing its prognostic value, evaluating treatme...

journal_title：Annals of internal medicine

authors： Janes H,Pepe MS,Bossuyt PM,Barlow WE

更新日期：2011-02-15 00:00:00

abstract：:The causes, therapy for, and consequences of hypernatremia in elderly patients are not well understood. We found that in 15,187 consecutive hospital admissions, 162 (1.1%) patients who were at least 60 years of age had serum sodium levels that measured greater than 148 meq/L. Of that 162, 57% had become hypernatremic ...

journal_title：Annals of internal medicine

authors： Snyder NA,Feigal DW,Arieff AI

更新日期：1987-09-01 00:00:00