NIH conference. Hepatocellular carcinoma.

abstract：:Medically unexplained functional or somatization symptoms are somatic disorders that are not adequately explained by physical disease processes. The way in which these disorders have been understood and managed has varied over the history of medicine. However, only in the past 100 years has the "mental" explanation pr...

journal_title：Annals of internal medicine

authors： Sharpe M,Carson A

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Noninvasive testing for Helicobacter pylori is widely available and has been considered as an initial management strategy for uninvestigated dyspepsia. However, data to guide clinicians in the management of patients with dyspepsia who are seropositive for H. pylori are lacking. OBJECTIVE:To examine the econ...

journal_title：Annals of internal medicine

authors： Ofman JJ,Etchason J,Fullerton S,Kahn KL,Soll AH

更新日期：1997-02-15 00:00:00

abstract：OBJECTIVE:To determine whether laboratory findings showing antibodies to hepatitis C virus (HCV) in patients with autoimmune hepatitis represent false-positive results and to identify possible explanations for true-positive results in these patients. DESIGN:Cross-sectional. SETTING:University-based hospital. PATIENT...

journal_title：Annals of internal medicine

authors： Nishiguchi S,Kuroki T,Ueda T,Fukuda K,Takeda T,Nakajima S,Shiomi S,Kobayashi K,Otani S,Hayashi N

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Recent guidelines for adult prevention do not recommend a comprehensive annual physical examination, but current public expectations in light of this change are unknown. OBJECTIVE:To determine public belief in the need for and content of an annual physical examination and to examine the effect of financial ...

journal_title：Annals of internal medicine

authors： Oboler SK,Prochazka AV,Gonzales R,Xu S,Anderson RJ

更新日期：2002-05-07 00:00:00

abstract：OBJECTIVE:To determine the effect of a resistance-training program on walking endurance in a healthy, community-dwelling elderly population. DESIGN:12- week randomized, controlled trial comparing a resistance- training group with a nonexercising control group. SETTING:Hospital-affiliated outpatient exercise facility....

journal_title：Annals of internal medicine

authors： Ades PA,Ballor DL,Ashikaga T,Utton JL,Nair KS

更新日期：1996-03-15 00:00:00

abstract：OBJECTIVE:To determine whether low bone density and other risk factors for osteoporosis are associated with stress fractures in athletes. DESIGN:Case-control study. SETTING:Institutional sports injury clinic with primary and secondary care. PARTICIPANTS:Twenty-five athletes (nineteen women) with scintigraphically co...

journal_title：Annals of internal medicine

authors： Myburgh KH,Hutchins J,Fataar AB,Hough SF,Noakes TD

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:Observations that risk for colorectal cancer is elevated in patients with inflammatory bowel disease and that long-term use of anti-inflammatory drugs may reduce colorectal cancer risk have raised the possibility that inflammation may play a role in the development of colorectal cancer. While a recent prospe...

journal_title：Annals of internal medicine

authors： Zhang SM,Buring JE,Lee IM,Cook NR,Ridker PM

更新日期：2005-03-15 00:00:00

abstract：:The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including PIER (Physicians' Information and Education Resource) and MKSAP (Medical Knowledge and Self Assessment Program). Annals of Internal Medicine editors develop In the Clinic f...

journal_title：Annals of internal medicine

authors： McDermott MT

更新日期：2009-12-01 00:00:00

abstract：:Research on assessing or managing medication adherence applies approaches from observational, interventional, and implementation science that spans many disciplines and demands coherent conceptualization, valid methods, appropriate analyses, and complete and accurate reporting. To ensure such reporting, the European S...

journal_title：Annals of internal medicine

authors： De Geest S,Zullig LL,Dunbar-Jacob J,Helmy R,Hughes DA,Wilson IB,Vrijens B

更新日期：2018-07-03 00:00:00

abstract：Background:Little is known about how physician time is allocated in ambulatory care. Objective:To describe how physician time is spent in ambulatory practice. Design:Quantitative direct observational time and motion study (during office hours) and self-reported diary (after hours). Setting:U.S. ambulatory care in 4 ...

journal_title：Annals of internal medicine

authors： Sinsky C,Colligan L,Li L,Prgomet M,Reynolds S,Goeders L,Westbrook J,Tutty M,Blike G

更新日期：2016-12-06 00:00:00

abstract：:Medical technology assessment seeks to improve the care of individual patients (the conventional unit of clinical practice) through evaluation studies conducted in groups of patients (the conventional unit of clinical investigation). This distinction between individuals and groups has practical relevance to the design...

journal_title：Annals of internal medicine

authors： Diamond GA,Denton TA

更新日期：1993-03-15 00:00:00

abstract：:Deaths and injuries from firearms are significant public health problems, and clinicians are in a unique position to identify risk among their patients and discuss the importance of safe firearm practices. Although clinicians may be ill-prepared to engage in such discussions, an adequate body of evidence is available ...

journal_title：Annals of internal medicine

authors： Pallin R,Spitzer SA,Ranney ML,Betz ME,Wintemute GJ

更新日期：2019-06-04 00:00:00

abstract：:Twenty-three patients with hyperparathyroidism from six families with the multiple endocrine adenomatosis (MEA) I-syndrome were tested by secretin provocation. In nine cases this led to increases in serum gastrin ranging from 298 to 13 300 pg/ml, whereas the maximum rise in gastrin in the other 14 patients was 32 pg/m...

journal_title：Annals of internal medicine

authors： Lamers CB,Buis JT,van Tongeren J

更新日期：1977-06-01 00:00:00

abstract：:The question of whether initial treatment is necessary in relatively asymptomatic patients with stage III and IV non-Hodgkin's lymphomas of favorable histologic types was studied by retrospective analysis. Two groups of patients were studied: [1] 44 nonprotocol patients, followed since 1963, in whom initial treatment ...

journal_title：Annals of internal medicine

authors： Portlock CS,Rosenberg SA

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:To describe the course of rheumatoid arthritis over 5 years in adults and to evaluate the effect of parenterally administered gold salts on that course. DESIGN:A prospective observational study of adults with rheumatoid arthritis. Data derived from annual interviews with patients from 1983 to 1988 and from p...

journal_title：Annals of internal medicine

authors： Epstein WV,Henke CJ,Yelin EH,Katz PP

更新日期：1991-03-15 00:00:00

abstract：BACKGROUND:Short-term aspirin therapy can lower the risk for venous thromboembolism (VTE) in high-risk patients, but whether the long-term use of low-dose aspirin reduces risk in healthy adults is uncertain. OBJECTIVE:To test the efficacy of long-term aspirin therapy for preventing VTE. DESIGN:Secondary analysis of a...

journal_title：Annals of internal medicine

authors： Glynn RJ,Ridker PM,Goldhaber SZ,Buring JE

更新日期：2007-10-16 00:00:00

abstract：:The growing population of older persons in our society will require increased attention. It is contended that the current pattern of third-party reimbursement for hospitalization and technical procedures focuses upon acute care and cure. The philosophy underlying medical education and practice is a barrier to the prov...

journal_title：Annals of internal medicine

authors： Eisdorfer C

更新日期：1981-02-01 00:00:00

abstract：SOURCE CITATION:Cao B, Wang Y, Wen D, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19. N Engl J Med. 2020;382:1787-99. 32187464. ...

journal_title：Annals of internal medicine

authors： Yang P,Tekwani S,Martin GS

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:Thymectomy is standard therapy fornonthymomatousmyasthenia gravis despite the absence of randomized clinical trials (1). Myasthenia gravis is uncommonly reported in monozygous twins; disease concordance occurs in approximately one third of such identical twin pairs; and treatment for myasthenia gravis, when ...

journal_title：Annals of internal medicine

authors： Riggs KR,Gutmann L,Riggs JE

更新日期：2011-10-04 00:00:00

abstract：PURPOSE:Cost-utility analysis is a type of cost-effectiveness analysis in which health effects are measured in terms of quality-adjusted life-years (QALYs) gained. Such analyses have become popular for examining the health and economic consequences of health and medical interventions, and they have been recommended by ...

journal_title：Annals of internal medicine

authors： Neumann PJ,Stone PW,Chapman RH,Sandberg EA,Bell CM

更新日期：2000-06-20 00:00:00

abstract：BACKGROUND:Hypertension often persists after adrenalectomy for primary aldosteronism. OBJECTIVE:To determine factors associated with resolution of hypertension after adrenalectomy for primary aldosteronism. DESIGN:Retrospective cohort study. SETTING:Tertiary care referral center in Rochester, Minnesota. PATIENTS:Al...

journal_title：Annals of internal medicine

authors： Sawka AM,Young WF,Thompson GB,Grant CS,Farley DR,Leibson C,van Heerden JA

更新日期：2001-08-21 00:00:00

abstract：OBJECTIVE:To evaluate the relation between weight variability and death in high-risk, middle-aged men participating in the Multiple Risk Factor Intervention Trial (MRFIT). DESIGN:Cohort study with 3.8 years of follow-up. SETTING:Multicenter, collaborative, primary prevention trial conducted at 22 clinical centers in ...

journal_title：Annals of internal medicine

authors： Blair SN,Shaten J,Brownell K,Collins G,Lissner L

更新日期：1993-10-01 00:00:00

abstract：:In an effort to prevent cytomegalovirus infection among seronegative patients having marrow transplants, a globulin with high antibody levels against cytomegalovirus was given before and for 11 weeks after transplantation in a randomized trial. Among 36 patients who received no prophylactic granulocyte transfusions, g...

journal_title：Annals of internal medicine

authors： Meyers JD,Leszczynski J,Zaia JA,Flournoy N,Newton B,Snydman DR,Wright GG,Levin MJ,Thomas ED

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Hospice providers contend that enrollment reduces the cost of the Medicare programs, but estimates of effects are dated, methodologically limited, and focused on persons with cancer. OBJECTIVE:To estimate the effects of hospice care on Medicare program payments during the last year of life from 1996 to 1999...

journal_title：Annals of internal medicine

authors： Campbell DE,Lynn J,Louis TA,Shugarman LR

更新日期：2004-02-17 00:00:00

abstract：BACKGROUND:In AIDS, nodular skin disease can result from various causes. OBJECTIVE:To report a new manifestation of microsporidial infection presenting as nodular skin disease with underlying osteomyelitis. DESIGN:Case report. SETTING:Tertiary-care military medical center in Washington, D.C. PATIENT:A 36-year-old w...

journal_title：Annals of internal medicine

authors： Kester KE,Turiansky GW,McEvoy PL

更新日期：1998-06-01 00:00:00

abstract：Background:Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). Objective:To determine the safety and efficacy of Triplex. Design:First-in-patient, phase 2 trial. (ClinicalTrials.gov: NCT02506933). Setting:3...

journal_title：Annals of internal medicine

authors： Aldoss I,La Rosa C,Baden LR,Longmate J,Ariza-Heredia EJ,Rida WN,Lingaraju CR,Zhou Q,Martinez J,Kaltcheva T,Dagis A,Hardwick N,Issa NC,Farol L,Nademanee A,Al Malki MM,Forman S,Nakamura R,Diamond DJ,TRIPLEX VACCINE St

更新日期：2020-03-03 00:00:00

abstract：:We tested the relative efficacy of bronchodilators delivered in aerosol and in oral form in 17 patients with asthma in a double-blind randomized sequence. Treatment consisted of a 20-mg tablet of metaproterenol sulfate, five puffs of metaproterenol aerosol (0.65 mg in each puff for a total of 3.25 mg) administered 20 ...

journal_title：Annals of internal medicine

authors： Shim C,Williams MH Jr

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:Exercise stress testing in patients with abdominal aortic aneurysms may cause enlargement or rupture of aneurysms. OBJECTIVE:To evaluate the safety of treadmill exercise stress testing in patients with abdominal aortic aneurysms. DESIGN:Retrospective descriptive study. SETTING:Tertiary care center. PATIE...

journal_title：Annals of internal medicine

authors： Best PJ,Tajik AJ,Gibbons RJ,Pellikka PA

更新日期：1998-10-15 00:00:00

abstract：BACKGROUND:Experts consider health information technology key to improving efficiency and quality of health care. PURPOSE:To systematically review evidence on the effect of health information technology on quality, efficiency, and costs of health care. DATA SOURCES:The authors systematically searched the English-lang...

journal_title：Annals of internal medicine

authors： Chaudhry B,Wang J,Wu S,Maglione M,Mojica W,Roth E,Morton SC,Shekelle PG

更新日期：2006-05-16 00:00:00

abstract：OBJECTIVE:To determine whether the detection of tuberculostearic acid (TBSA) in bronchial aspirate and bronchoalveolar lavage specimens is useful for the rapid diagnosis of active pulmonary tuberculosis in patients suspected of having the disease. SETTING:A pulmonary clinic in a teaching hospital. PATIENTS:Forty pati...

journal_title：Annals of internal medicine

authors： Pang JA,Chan HS,Chan CY,Cheung SW,French GL

更新日期：1989-10-15 00:00:00