Abstract:
OBJECTIVE:To determine whether abnormalities in the function of the autonomic nervous system are associated with oral and ocular dryness in rheumatoid arthritis. METHODS:Pupillography was done using an infrared light reflection method (IRIS) to measure both parasympathetic function (constriction latency and the latency of maximum constriction velocity (MCV)) and sympathetic function (dilatation latency) in rheumatoid arthritis patients with and without ocular dryness. The Schirmer and Saxon tests were used to measure the tear and saliva production respectively. RESULTS:The Schirmer and Saxon test results in rheumatoid arthritis patients with ocular dryness were reduced (P < 0.05) compared with rheumatoid arthritis patients without ocular dryness and healthy controls. Constriction latency and MCV latency were prolonged in rheumatoid arthritis patients with ocular dryness compared to the other two groups (P < 0.05). A negative correlation was found between the degree of ocular dryness and both constriction latency and MCV latency. No correlation was found between the results of pupillography and saliva production. CONCLUSIONS:Parasympathetic dysfunction may play a role in ocular dryness in patients with rheumatoid arthritis.
journal_name
Ann Rheum Disjournal_title
Annals of the rheumatic diseasesauthors
Barendregt PJ,van der Heijde GL,Breedveld FC,Markusse HMdoi
10.1136/ard.55.9.612subject
Has Abstractpub_date
1996-09-01 00:00:00pages
612-5issue
9eissn
0003-4967issn
1468-2060journal_volume
55pub_type
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2009-03-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2004-09-01 00:00:00
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journal_title:Annals of the rheumatic diseases
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doi:10.1136/annrheumdis-2016-209718
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2018-12-01 00:00:00
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journal_title:Annals of the rheumatic diseases
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doi:10.1136/ard.62.7.607
更新日期:2003-07-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/ard.50.1.55
更新日期:1991-01-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
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更新日期:2002-04-01 00:00:00
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journal_title:Annals of the rheumatic diseases
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pub_type: 杂志文章
doi:10.1136/ard.61.2.137
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/annrheumdis-2013-204851
更新日期:2015-06-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/ard.48.6.455
更新日期:1989-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1136/ard.37.4.366
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pub_type: 杂志文章
doi:10.1136/annrheumdis-2013-204309
更新日期:2015-06-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/ard.2006.062018
更新日期:2007-08-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/ard.2007.072686
更新日期:2008-01-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/ard.40.2.182
更新日期:1981-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1136/ard.2003.018325
更新日期:2004-12-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/ard.2007.075945
更新日期:2007-10-01 00:00:00
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journal_title:Annals of the rheumatic diseases
pub_type: 杂志文章
doi:10.1136/annrheumdis-2014-205779
更新日期:2015-12-01 00:00:00