Background levels of non-ortho-substituted (coplanar) polychlorinated biphenyls in human serum of Missouri residents.

Abstract:

:This study characterizes the levels of polychlorinated biphenyls (PCB) congeners PCB 77, PCB 81, PCB 126, and PCB 169, in a group of 150 men and women with no documented exposure to PCBs. Its purpose is to provide current referent levels of coplanar PCBs in Missouri residents and to compare those levels to levels reported in the literature from the United States and other countries. Although this study used an extensive questionnaire assessing potential sources of exposure, no positive relations were found between these exposure sources and participants' PCB levels. The PCB levels for the four congeners measured were lower than any reported in the literature. PCBs 126 and 169 are only two of the dioxin-like congeners; however, their contribution makes up 11% of the total TEQ. Age was significantly related to PCB 126 and PCB 169. For every one-year increase in age, both PCB congeners increased by approximately 0.4 parts per trillion (ppt). There was no gender difference for PCB 126; however, PCB 169 levels were 3 ppt higher in males than females.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Shadel BN,Evans RG,Roberts D,Clardy S,Jordan-Izaguirre D,Patterson DG Jr,Needham LL

doi

10.1016/s0045-6535(00)00457-4

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

967-76

issue

4-7

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(00)00457-4

journal_volume

43

pub_type

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