A quantitative cytological study of lesional and non-lesional mucosa in oral lichen planus.

Abstract:

:Smears of buccal mucosa, dorsal surface of the tongue and floor of mouth were taken from 10 patients with histologically confirmed oral lichen planus and 12 healthy age- and sex-matched controls. In buccal smears, no significant differences in cytoplasmic and nuclear areas were observed between lesional, adjacent non-lesional and control tissues. However, the cytoplasmic area in smears from lichen planus lesions on the dorsum of the tongue and adjacent clinically normal mucosa was reduced compared with healthy controls. The cytoplasmic: nuclear ratio in smears from clinically normal floor of mouth in oral lichen planus was similarly reduced. Papanicolaou-stained smears from buccal lichen planus showed increased keratinization compared with normal buccal mucosa. These findings demonstrate that quantitative cytology can detect both cytoplasmic and nuclear changes in oral lichen planus.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Sugerman PB,Savage NW,Williams SL,Joynson OB,Daley TJ,Cowpe JG

doi

10.1016/0003-9969(95)00106-9

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

117-20

issue

1

eissn

0003-9969

issn

1879-1506

pii

0003996995001069

journal_volume

41

pub_type

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