Fibroids and infertility: a systematic review of the evidence.

Abstract:

UNLABELLED:A systematic literature review was performed to determine whether leiomyomata are associated with decreased fertility rates, and whether surgical removal increases fertility rates postoperatively. Meta-analysis was conducted when multiple studies addressed a single issue and were sufficiently homogeneous. Data were analyzed for effect of any fibroid upon fertility, as well as specific fibroid location. Results of studies comparing women with infertility and fibroids versus infertile controls showed widely disparate results. Subgroup analysis failed to indicate any effect on fertility of fibroids that did not have a submucous component. Conversely, women with submucous myomas demonstrated lower pregnancy rates (RR 0.30; 95% confidence interval [CI] 0.13--0.70) and implantation rates (RR 0.28; 95% CI 0.10--0.72) than infertile controls. Results of surgical intervention were similar. When all fibroid locations were considered together, myomectomy results were again widely disparate. However, when women with submucous myomas were considered separately, pregnancy was increased after myomectomy compared with infertile controls (RR 1.72; 95% CI 1.13--2.58) and delivery rates were now equivalent to infertile women without fibroids (RR 0.98; 95% CI 0.45--2.41). The current data suggest that only those fibroids with a submucosal or an intracavitary component are associated with decreased reproductive outcomes, and that hysteroscopic myomectomy may be of benefit. TARGET AUDIENCE:Obstetricians & Gynecologists, Family Physicians LEARNING OBJECTIVES:After completion of this article, the reader will be able to summarize the data on the role of fibroids and infertility, describe the effect of myomectomy on fertility, and list the methods used to evaluate intracavitary fibroids.

journal_name

Obstet Gynecol Surv

authors

Pritts EA

doi

10.1097/00006254-200108000-00022

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

483-91

issue

8

eissn

0029-7828

issn

1533-9866

journal_volume

56

pub_type

杂志文章,评审
  • Intracytoplasmic sperm injection: what are the risks?

    abstract:UNLABELLED:Intracytoplasmic sperm injection, a relatively new technique used at the time of in vitro fertilization to fertilize human oocytes, has provided couples with very severe male factor infertility the ability to conceive their own biologic children. Many men with severe oligospermia or azoospermia can now pass ...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/00006254-200001000-00024

    authors: Givens CR

    更新日期:2000-01-01 00:00:00

  • Metformin in obstetric and gynecologic practice: a review.

    abstract::Metformin is a common treatment for women who have insulin resistance manifesting as type 2 diabetes or polycystic ovarian syndrome (PCOS). With an increasing number of these patients conceiving, it is expected that the use of metformin in and around the time of pregnancy will increase. This article reassesses the mec...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/01.OGX.0000109224.52893.B8

    authors: McCarthy EA,Walker SP,McLachlan K,Boyle J,Permezel M

    更新日期:2004-02-01 00:00:00

  • Association of eclampsia and hydatidiform mole: case report and review of the literature.

    abstract::A patient with a hydatidiform mole complicated by eclampsia is presented. The findings from 57 other cases discovered in a review of the literature since 1866 are summarized to define the clinical characteristics of women experiencing eclampsia as a manifestation of their hydatidiform mole. Eclampsia complicating a mo...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:

    authors: Newman RB,Eddy GL

    更新日期:1988-04-01 00:00:00

  • Infectious disease and reproductive health: a review.

    abstract:UNLABELLED:Human reproduction provides unique opportunities for the transmission of infectious agents. Furthermore, the mother and her offspring have distinct susceptibilities to infection at each stage of reproduction, from conception and gestation to parturition and the neonatal period. The impact of pathogens on rep...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0b013e3181c9e7a1

    authors: Baecher-Lind LE,Miller WC,Wilcox AJ

    更新日期:2010-01-01 00:00:00

  • Multitasking human endometrium: a review of endometrial biopsy as a diagnostic tool, therapeutic applications, and a source of adult stem cells.

    abstract:UNLABELLED:The endometrium is one of the most fascinating tissues in the human body. Its sole purpose is to enable implantation of an embryo during a very short window of opportunity in the menstrual cycle. When implantation does not take place, the endometrial cells are shed, enabling growth of a new endometrial layer...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0b013e318195136f

    authors: Revel A

    更新日期:2009-04-01 00:00:00

  • Current First-line Therapy for Ovarian Cancer: A Comprehensive Review.

    abstract:Importance:Ovarian, fallopian tube, and primary peritoneal cancers constitute the deadliest gynecologic malignancies. After primary cytoreductive surgery, there are several standard first-line cytotoxic treatments for providers to consider. Newer molecular targeted therapies are becoming more common and may have a role...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0000000000000613

    authors: Pierce SR,Clark LH

    更新日期:2018-11-01 00:00:00

  • Menstrual Hygiene Management in Resource-Poor Countries.

    abstract:Importance:Adequate management of menstrual hygiene is taken for granted in affluent countries; however, inadequate menstrual hygiene is a major problem for girls and women in resource-poor countries, which adversely affects the health and development of adolescent girls. Objective:The aim of this article is to review...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0000000000000443

    authors: Kuhlmann AS,Henry K,Wall LL

    更新日期:2017-06-01 00:00:00

  • Late postpartum eclampsia: examples and review.

    abstract::Eclampsia, defined as the occurrence of seizures in pregnant women, usually in the setting of preeclampsia and in the absence of other neurologic disorders, occurs mainly before, during , or within 48 hours after delivery. When convulsions occur later postpartum, diagnosis is difficult and treatment disputed. We revie...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/01.ogx.0000219564.65999.0d

    authors: Hirshfeld-Cytron J,Lam C,Karumanchi SA,Lindheimer M

    更新日期:2006-07-01 00:00:00

  • Ectopic pregnancy: incidence and review of determinant factors.

    abstract::The incidence of ectopic pregnancies has been expressed in various ways that are not comparable and provide widely differing estimates due to individual definitions of the denominator. Population-based data are presented based on a count of all ectopic pregnancies reported in short stay hospitals in Maine, Rhode Islan...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:

    authors: Barnes AB,Wennberg CN,Barnes BA

    更新日期:1983-06-01 00:00:00

  • Genetic factors in preterm delivery.

    abstract::Tens of thousands of children deliver before they are full term each year. Although many social, environmental, and medical risk factors have been suggested, the etiology of a large percentage of preterm labor cases is still unknown. It has been noted for many years that preterm delivery is a condition that runs in fa...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/00006254-199903000-00025

    authors: Hoffman JD,Ward K

    更新日期:1999-03-01 00:00:00

  • Why Do Women Not Use Preconception Care? A Systematic Review On Barriers And Facilitators.

    abstract:Importance:Preconception care (PCC) has the potential to optimize pregnancy outcomes. However, awareness of PCC among the target population is generally limited, and the use of PCC remains low. Importance:The objective of this study was to review the literature on women's perceptions regarding barriers and facilitator...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0000000000000360

    authors: Poels M,Koster MP,Boeije HR,Franx A,van Stel HF

    更新日期:2016-10-01 00:00:00

  • U.S. women's perceptions of and attitudes about the IUD.

    abstract::Two recent surveys provide insights into U.S. women's attitudes toward and perceptions of the IUD. The first study was based on in-depth interviews conducted with 300 women 21-54 years of age in 6 cities; the second was based on telephone interviews with 1852 low-income, predominantly Black and Hispanic women 18-34 y...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/00006254-199612000-00012

    authors: Forrest JD

    更新日期:1996-12-01 00:00:00

  • Diagnosis of vaginal discharge by wet mount microscopy: a simple and underrated method.

    abstract:UNLABELLED:Vaginal discharge is highly variable in quality and quantity among different individuals, and even in the same individual during different periods of life. Vaginal discharge is most commonly caused by infection with sexually transmitted organisms or increased colonization by different facultative pathogenic ...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0b013e31822bdf31

    authors: Mylonas I,Bergauer F

    更新日期:2011-06-01 00:00:00

  • Paternal Preferences, Perspectives, and Involvement in Perinatal Decision Making.

    abstract:Importance:Despite increasing attention to the importance of father involvement during pregnancy, the literature on fathers' roles in perinatal decision making is scant. Objective:The aim of this study was to conduct a narrative review of the literature exploring fathers' preferences, perspectives, and involvement in ...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0000000000000650

    authors: Cheng ER,McGough H,Tucker Edmonds B

    更新日期:2019-03-01 00:00:00

  • Toxemia of pregnancy and eclampsia.

    abstract::The various phenomena of toxemia of pregnancy both in primiparous and multiparous women may be explained by postulating a defect in the calcium transport mechanism, both in the smooth muscle of the uterus and vascular smooth muscle as well as a similar defect in platelets. The involvement of prostaglandin E has not be...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/00006254-198005000-00028

    authors: Mendlowitz M

    更新日期:1980-05-01 00:00:00

  • Ontogeny: the evolution of an oocyte.

    abstract::The physiology of oocyte development, maturation, and selection forms the basis for understanding ovarian follicle dynamics, reproductive function and ovulation induction. The number of ovarian follicles with which women are invested from birth and the rate of decline determine their reproductive lifespan. The process...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-200007000-00024

    authors: Yap C

    更新日期:2000-07-01 00:00:00

  • Preembryo research: medical aspects and ethical considerations.

    abstract::Recent advances in the field of reproduction have made it possible to obtain preembryos and to use them in many research applications. These include research into improving methods of IVF treatment, contraceptive research, preimplantation diagnosis, gene therapy, the study of malignant disease, and others. The benefit...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-199709000-00022

    authors: Eisenberg VH,Schenker JG

    更新日期:1997-09-01 00:00:00

  • Bacterial vaginosis in pregnancy.

    abstract::Bacterial vaginosis is a clinical condition caused by replacement of the normal hydrogen peroxide producing Lactobacillus sp. in the vagina with high concentrations of characteristic sets of aerobic and anaerobic bacteria. Bacterial vaginosis is the most prevalent cause of vaginal discharge or malodor, although 50 per...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-200005001-00001

    authors: McGregor JA,French JI

    更新日期:2000-05-01 00:00:00

  • The Marshall-Marchetti-Krantz procedure: a critical review.

    abstract::The success of the Marshall-Marchetti-Krantz procedure is reviewed in 56 articles that were predominantly retrospective analyses. The overall success rate was 86.1 per cent in 2712 cases, with 92.1 per cent in primary and 84.5 per cent in repeat procedures. An overall complication rate of 21.1 per cent was calculated....

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-198812000-00003

    authors: Mainprize TC,Drutz HP

    更新日期:1988-12-01 00:00:00

  • Public health implications of cesarean on demand.

    abstract::Cesarean rates have been rising in the United States. Recently, there has been an upsurge of interest in "cesarean on maternal request" in the absence of any medical indication, a phenomenon that will further increase the cesarean rate. This trend may not be benign on a population basis, and reliable data are lacking....

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/01.ogx.0000248826.44123.73

    authors: Plante LA

    更新日期:2006-12-01 00:00:00

  • The safety of quinolones in pregnancy.

    abstract::Quinolones and fluoroquinolones are highly efficient antibiotics. However, concerns regarding possible harmful effects have limited their use during pregnancy. Nevertheless, accumulating clinical data suggest that they may be safe during pregnancy. This review aimed to explore the mechanisms of action of the quinolone...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0000000000000122

    authors: Yefet E,Salim R,Chazan B,Akel H,Romano S,Nachum Z

    更新日期:2014-11-01 00:00:00

  • Thrombophilia screening in pregnancy.

    abstract:UNLABELLED:Thromboembolism in pregnancy is a major contributor to pregnancy morbidity and mortality with potentially serious adverse effects for both mother and fetus. The purposes of this article are to explore the impact of heritable and acquired thrombophilias on pregnancy and to determine the appropriateness of scr...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/01.ogx.0000165116.96026.4e

    authors: Jordaan DJ,Schoon MG,Badenhorst PN

    更新日期:2005-06-01 00:00:00

  • Pregnancy in patients with idiopathic thrombocytopenic purpura: assessing the risks for the infant at delivery.

    abstract::The objective of this review is to estimate the risk of severe thrombocytopenia at birth and minor or major morbidity for the infant of a pregnancy complicated by immune thrombocytopenic purpura. English language publications on immune thrombocytopenic purpura in pregnancy from January 1980 to December 1990 were used....

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-199312000-00003

    authors: Burrows RF,Kelton JG

    更新日期:1993-12-01 00:00:00

  • Contemporary clinical issues in outpatient obstetrics and gynecology: findings of the Collaborative Ambulatory Research Network, 2001-2004: part I.

    abstract::Obstetrician/gynecologists are taking on more primary care responsibilities and thus are expected to have a wider base of medical knowledge on a variety of women's health issues. The Collaborative Ambulatory Research Network (CARN) was created in 1990 to investigate issues pertinent to women's health and to the practi...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/01.ogx.0000143775.07827.bb

    authors: Coleman VH,Power ML,Zinberg S,Schulkin J

    更新日期:2004-11-01 00:00:00

  • Torsion in the Gravid and Nongravid Uterus: A Review of the Literature of an Uncommon Diagnosis.

    abstract:Importance:Uterine torsion is an uncommon but life-threatening clinical situation that requires a high index of suspicion for diagnosis. Objective:The aim of this study was to review literature and determine the etiology, presentation, diagnosis, and management of uterine torsion in the gravid and nongravid patients. ...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0000000000000767

    authors: Ramseyer AM,Whittington JR,Resendez VA,Whitcombe DD,Magann EF

    更新日期:2020-04-01 00:00:00

  • Relevance of molecular medicine to clinical obstetrics and gynecology.

    abstract::Understanding molecular biology can improve the clinical acumen of the practicing obstetrician/gynecologist. An area of basic research now becoming clinically relevant involves the G proteins and G protein-coupled receptors. Clinicians already manipulate G protein-coupled receptors in their daily practice. Examples in...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-199701000-00025

    authors: Cohen DP,Layman LC

    更新日期:1997-01-01 00:00:00

  • Role of complementary and alternative medicine to achieve fertility in uninsured patients.

    abstract:UNLABELLED:Among those facing infertility in the United States, underinsured and uninsured women are at the greatest disadvantage. Women who receive medical care under Medicaid are rarely covered for infertility testing; only 4 states will cover infertility treatment as an element of family planning and preconception c...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/OGX.0b013e318286f780

    authors: Perry TE,Hirshfeld-Cytron J

    更新日期:2013-04-01 00:00:00

  • Massive transfusion: a current review.

    abstract::The use of blood products has come under closer scrutiny over the past decade because of the autoimmune deficiency syndrome. Newer technology has led to the use of component therapy in most situations. The use of fresh-frozen plasma has been overstated in the older literature, and fresh-frozen plasma should be used in...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-199105000-00015

    authors: Nolan TE,Gallup DG

    更新日期:1991-05-01 00:00:00

  • Polycystic Ovary Syndrome: Impact of Lipotoxicity on Metabolic and Reproductive Health.

    abstract:Importance:Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-aged women. Women with PCOS are at increased risk of developing several metabolic and reproductive abnormalities, including metabolic syndrome. Underlying the combined metabolic and reproductive dysfunction is lipotoxicity, de...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章

    doi:10.1097/OGX.0000000000000661

    authors: Brennan KM,Kroener LL,Chazenbalk GD,Dumesic DA

    更新日期:2019-04-01 00:00:00

  • Scleroderma in pregnancy.

    abstract::We conducted a detailed literature search for the rare combination of scleroderma and pregnancy. Ninety-four patients were reported, 14 of whom died during the course of the pregnancy, mainly due to secondary renal and cardiopulmonary involvement. Out of the 95 fetuses, 19 were lost. Thus, when complications arise, th...

    journal_title:Obstetrical & gynecological survey

    pub_type: 杂志文章,评审

    doi:10.1097/00006254-198907000-00007

    authors: Maymon R,Fejgin M

    更新日期:1989-07-01 00:00:00