Ontogeny: the evolution of an oocyte.

Abstract:

:The physiology of oocyte development, maturation, and selection forms the basis for understanding ovarian follicle dynamics, reproductive function and ovulation induction. The number of ovarian follicles with which women are invested from birth and the rate of decline determine their reproductive lifespan. The processes of atresia and apoptosis constantly deplete this finite store. The initiation of follicle growth involves complex chemical signaling and ensures that a cohort of follicles is prepared for recruitment monthly. The effects of gonadotrophins, autocrine signals, and the degree of vascularization further determine dominance and the selection of an oocyte for ovulation.

journal_name

Obstet Gynecol Surv

authors

Yap C

doi

10.1097/00006254-200007000-00024

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

449-54

issue

7

eissn

0029-7828

issn

1533-9866

journal_volume

55

pub_type

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