Abstract：
OBJECTIVE:To assess the benefit resulting from the use of abciximab associated with primary angioplasty. The following parameters were analyzed in-hospital, at 30 days, and 6 months: (a) flow in the culprit artery; (b) ventricular function; (c) combined outcome of death, acute myocardial infarction, and additional revascularization. METHODS:From November 1997 to June 1999, a longitudinal nonrandomized study with historical data of 137 patients with acute myocardial infarction within the first 12 hours. Patients undergoing primary angioplasty and were divided into 2 groups: those receiving (A) abciximab (26) or (B) conventional therapy (111). TIMI flow and regional ventricular function estimated by the standard deviation (SD)/chordis index were analyzed. RESULTS:At the end of angioplasty, TIMI 3 flow was observed in 76.9% and 83.8% of the patients in groups A and B, respectively (P=0.58). In the reevaluation, patients with TIMI flow <3 showed a 100% improvement in group A and a 33% in group B (P<0.0001). A significant improvement (P<0.0001) in regional ventricular function, by SD/chordis index, occurred in each group; no significant difference between groups however, was observed (29.9% x 20.2%; P=0.58). A nonsignificant reduction in the combined outcome in the in-hospital phase (3.85% A x 9.0% B; P=0.34) and on the 30th day (4.0% x 12.0%; P=0.22) was observed in group A. CONCLUSION:Abciximab improved blood flow. Primary angioplasty improved regional ventricular function independent of antithrombotic therapy. Abciximab showed a trend toward reducing the combined outcome in the in-hospital phase and on the 30th day.
journal_name
Arq Bras Cardioljournal_title
Arquivos brasileiros de cardiologiaauthors
Brito ML,Souza Filho NF,Moura V AV,Lavalle LA,Darwich RZ,Leal M,Munhoz ECdoi
10.1590/s0066-782x2002000100008subject
Has Abstractpub_date
2002-01-01 00:00:00pages
90-105issue
1eissn
0066-782Xissn
1678-4170pii
S0066-782X2002000100008journal_volume
78pub_type
杂志文章abstract：OBJECTIVE:To assess the relation between the evolution of cognitive performance and the prognosis of elderly patients after compensation of advanced heart failure. METHODS:Thirty-one patients older than 64 (68 +/- 7) years and admitted with New York Heart Association class IV heart failure and ejection fraction = 0.45...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2004000300005
更新日期：2004-03-01 00:00:00
abstract：:A 78-year-old patient presented with shortness of breath after falling down. Transthoracic echocardiogram showed an extensive thrombus in the right atrium (RA), extensive thrombosis of the inferior vena cava (IVC), and abdominal aortic aneurysm (AAA). A magnetic resonance confirmed the thrombosis of the RA extending t...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20160143
更新日期：2016-10-01 00:00:00
abstract：:The case of a 19-year-old young man with clinical picture of congestive heart failure and supraventricular tachycardia is reported. Heart failure got better with conventional treatment, but the tachycardia persisted in spite of antiarrhythmic drugs. Echocardiogram showed dilated cardiomyopathy of important degree and ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：BACKGROUND:The exercise treadmill test can be used in ventricular dysfunction patients for functional capacity or predicting prognosis. The cardiac image with 123I MIBG shows cardiac sympathetic activation. OBJECTIVE:To evaluate the relationship between exercise treadmill test variables and cardiac image changes in 12...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2011005000044
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Chronic heart failure (CHF) is a complex syndrome which comprises structural and functional alterations in the heart in maintaining the adequate blood demand to all tissues. Few investigations sought to evaluate oxidative DNA damage in CHF. OBJECTIVE:To quantify the DNA damage using the comet assay in left ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.36660/abc.20180198
更新日期：2020-02-01 00:00:00
abstract：PURPOSE:To study mononuclear magnesium and serum cations (Na, K and Mg) in elderly hypertensive patients treated with hydrochlorothiazide during 90 days. PATIENTS AND METHODS:15 elderly hypertensive patients treated with hydrochlorothiazide, 25 mg/day or placebo. A method of freezing produced total lysis of the cells;...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：BACKGROUND:Data from over 4 decades have reported a higher incidence of silent infarction among patients with diabetes mellitus (DM), but recent publications have shown conflicting results regarding the correlation between DM and presence of pain in patients with acute coronary syndromes (ACS). OBJECTIVE:Our primary o...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20140106
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:Assess the prevalence of white coat hypertension in the municipality of Dumont, in São Paulo State, and map study participants' demographics, and physiologic and metabolic changes. METHODS:One hundred and nine (109) users of the Municipal Health Service were selected and then divided into three groups: normo...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Stress is defined as a complicated state that related to homeostasis disturbances, over-activity of the sympathetic nervous system and hypothalamus-pituitary-adrenal axis responses. Cardiac preconditioning reduces myocardial damages. OBJECTIVE:This study was designed to assess the cardioprotective effects o...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20190189
更新日期：2019-10-10 00:00:00
abstract：BACKGROUND:Cardiovascular surgery has been undergoing transformations due to the advancement of percutaneous techniques, clinical treatment and primary prevention. OBJECTIVE:Evaluation of incidence and mortality of heart surgeries performed at the Instituto do Coração (InCor-HCFMUSP). METHODS:Using database from the ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2010000200006
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:Radiofrequency ablation (RFA) in children is an increasingly common practice. OBJECTIVE:To evaluate, in our institution, the results of RFA in children younger than 15 years. METHODS:A total of 125 children submitted to RFA between May 1991 and May 2010 were analyzed. RESULTS:Sixty-seven (53.6%) children ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2012005000042
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Chemotherapy with doxorubicin and cyclophosphamide, although efficient for treating breast cancer, is associated with cardiovascular complications. Recent studies seek to identify methods that can early detect cardiological and vascular changes as a strategy to decrease the incidence of cardiovascular comorb...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20180168
更新日期：2018-11-01 00:00:00
abstract：:This is the case of a 42 year-old male with systemic amyloidosis, probably primary, and heart involvement. Physiopathological and clinical aspects are described as well as the rarity of the diagnosis in vivo. The limited aspects of therapy are also described. ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x1998000200010
更新日期：1998-02-01 00:00:00
abstract：BACKGROUND:In the general population, regular practice of physical exercises is associated with improved physical capacity and reduction of cardiovascular events. Concerning patients with chronic kidney disease, a population with significant impairment of physical capacity and high rates of cardiovascular mortality, fe...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2010005000043
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND:In patients with systemic hypertension, microalbuminuria is a marker of endothelial damage and is associated with an increased risk for cardiovascular disease. OBJECTIVE:To determine the factors that may lead to the occurrence of microalbuminuria in hypertensive patients with serum creatinine lower than 1.5...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20130210
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:The incidence of hyperkalemia related to spironolactone use is low in stable heart failure; however, it has not been studied during decompensation. OBJECTIVE:To evaluate the influence of spironolactone on serum potassium in decompensated heart failure (HF). METHODS:In a cohort study, patients that had been...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2008001500009
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of cardiovascular disease (CVD) and traditional risk factors in patients with chronic renal failure undergoing evaluation for inclusion on the renal transplantation list. METHODS:One hundred ninety-five patients with dialytic chronic renal failure underwent clinical evaluation and...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2005000200012
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:Studies on the impact of HDL-c and the occurrence of cardiovascular disease (CV) in the elderly are scarce. OBJECTIVE:To evaluate the clinical and laboratory variables and the occurrence of CV events in elderly patients stratified according to the behavior of HDL-c during an eight-year follow up. METHODS:W...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2009000900006
更新日期：2009-09-01 00:00:00
abstract：:We report a case of chronic nonspecific constrictive pericarditis with myocardial involvement in a 19-month-old infant. The patient underwent total pericardiectomy and had irreversible hemodynamic instability. Constrictive pericarditis is rare in childhood. It may follow several processes, most frequently an infectiou...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Today, chronic kidney diseases represent a great challenge to public health as regards the acquisition of knowledge to support interventions that can slow the progression of renal function loss. OBJECTIVE:To analyze the magnitude of the renal function deficit in hypertensive adult patients and its relations...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20130102
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:The decrease in mortality due to cardiovascular diseases (CVD) has been achieved in the United States and the same decrease has been happening in developing countries, thanks to favorable changes in lifestyle and risk factors. Despite such consideration, the volume of information available on the distribution...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2005001400005
更新日期：2005-07-01 00:00:00
abstract：:The risk scores used as assistance agents in valve diseases are validated worldwide; however, the data are not homogeneous. The epidemiological characteristics of each population require local validation of these risk tools. The percutaneous valve replacement, which is a reality in valvular diseases (especially aortic...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2012000500018
更新日期：2012-05-01 00:00:00
abstract：:We report the case of a girl with chronic rheumatic valvar heart disease who developed infective endocarditis and two complications, ischemic stroke due to cerebral embolic event and mycotic aneurysm of the superior mesenteric artery. ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2007000100023
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To determine the value of pericardial biopsy as a complementary exam in the etiology of pericardial effusion. METHODS:We analyzed retrospectively (from 1990 to 1997) 38 patients with pericardial effusion. The age ranged between 3 months and 79 years (mean 41.15 +/- 21.78 years). Pericardial biopsy was performe...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x1998000600003
更新日期：1998-06-01 00:00:00
abstract：:A healthy 44 year-old male patient presented a calcified mass in the middle mediastinum on a chest film. During diagnostic investigation cineangiograms showed a rupture of the left sinus of Valsalva forming a large pseudoaneurysm that produced important distortion of the left coronary artery and it's main branches. Th...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：OBJECTIVE:To compare the prevalence of systemic hypertension in two different populations: a representative sample of the adult urban population of Porto Alegre, and individuals who sought blood pressure measurement in a hypertension prevention and control campaign. METHODS:A cross-sectional study was carried out invo...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2001000600002
更新日期：2001-06-01 00:00:00
abstract：:Contrast echocardiography is based on intravenous injection of microbubbles that act as blood flow tracers and increase ultra-sound signal. Contrast agents have shown to improve cardiac cavities opacification and endocardial border delineation in addition to helping perfusion evaluation. Contrast echocardiography has ...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.1590/s0066-782x2008001700015
更新日期：2008-11-01 00:00:00
abstract：PURPOSE:To evaluate the nitroglycerin patches efficacy and tolerability in patients with stable angina pectoris. METHODS:One thousand and five hundred and thirty nine patients with stable angina pectoris, mean age 61.0 +/- 10.3, 891 men and 648 women were prospectively evaluated by five hundred and thirty five special...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章,多中心研究
doi：
更新日期：1992-02-01 00:00:00
abstract：:A case of a 20 year old young man having the permanent form of junctional reciprocating tachycardia complicated by ventricular fibrillation (VF) is reported. A number of antiarrhythmic drugs either as single or combined therapy fail to control tachycardia. Paroxisms of a faster palpitation which never lasted longer th...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:Cardiac tumors are rare, mostly benign with high embolic potential. OBJECTIVES:To correlate the histological type of cardiac masses with their embolic potential, implantation site and long term follow up in patients undergoing surgery. METHODS:Between January 1986 and December 2011, we retrospectively anal...
journal_title：Arquivos brasileiros de cardiologia
pub_type： 杂志文章
doi：10.5935/abc.20140096
更新日期：2014-07-01 00:00:00
