Abstract:
BACKGROUND:Studies on the impact of HDL-c and the occurrence of cardiovascular disease (CV) in the elderly are scarce. OBJECTIVE:To evaluate the clinical and laboratory variables and the occurrence of CV events in elderly patients stratified according to the behavior of HDL-c during an eight-year follow up. METHODS:We evaluated 81 elderly patients, mean age of 68.51 +/- 6.32 years (38.2% male), in two stages (A1 and A2), with a minimum interval of five years. The subjects were divided into 3 groups according to HDL-c levels: normal HDL-c in both assessments (NG) (n = 31), low HDL-c in both assessments (LG) (n = 21) and variable HDL-c in A1 and A2 (VG) (n = 29). Main CV events were recorded: coronary heart disease (angina, myocardial infarction, percutaneous / surgical myocardial revascularization), stroke, transient ischemic attack, carotid disease, dementia and heart failure. RESULTS:The groups did not differ in gender and age in A1 and A2. Mean triglyceride levels were lower in the NG in A1 (p = 0.027) and A2 (p = 0.016) than in the LG. The distribution of CV events was as follows: 13 events in the NG (41.9%), 16 (76.2%) in the LG, and 12 (41.4%) in the VG (chi2 = 7.149, p = 0.024). The logistic regression analysis showed that the older the patient (OR = 1.187, p = 0.0230) and the lower the HDL-c (OR = 0.9372, p = 0.0102), the greater the occurrence of events CV. CONCLUSION:Permanently low HDL-c during eight years of monitoring is a risk factor for the development of CV events in the elderly.
journal_name
Arq Bras Cardioljournal_title
Arquivos brasileiros de cardiologiaauthors
Freitas EV,Brandão AA,Pozzan R,Magalhães ME,Fonseca F,Pizzi O,Campana E,Brandão APdoi
10.1590/s0066-782x2009000900006subject
Has Abstractpub_date
2009-09-01 00:00:00pages
231-8issue
3eissn
0066-782Xissn
1678-4170pii
S0066-782X2009000900006journal_volume
93pub_type
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journal_title:Arquivos brasileiros de cardiologia
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abstract::A case of pulmonary atresia with intact ventricular septum and a hypoplastic right ventricle, with three wall formed portions, that became naturally well developed until 2 years of age, is related. A Blalock-Taussig shunt had been performed early in life. Z value of tricuspid valve of 0.3 and left ventricular in ECG h...
journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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doi:10.1590/s0066-782x2000000700006
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journal_title:Arquivos brasileiros de cardiologia
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doi:
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pub_type: 杂志文章
doi:10.5935/abc.20170103
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,评审
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journal_title:Arquivos brasileiros de cardiologia
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doi:10.1590/s0066-782x2009000500008
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journal_title:Arquivos brasileiros de cardiologia
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doi:
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journal_title:Arquivos brasileiros de cardiologia
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doi:10.1590/s0066-782x2009000900016
更新日期:2009-09-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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journal_title:Arquivos brasileiros de cardiologia
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doi:10.1590/s0066-782x2012000600017
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2006000400005
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.1590/s0066-782x2002000200013
更新日期:2002-02-01 00:00:00
abstract:PURPOSE:To test the association between diabetes mellitus and ischaemic heart disease (IHD) in males and females, after adjusting for known confounders and/or modifiers of effect. METHODS:The study was designed as a case-control and the period of data collection was one year (March/93 until February/94). The associati...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
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journal_title:Arquivos brasileiros de cardiologia
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doi:
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journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章,评审
doi:10.1590/s0066-782x2007001500009
更新日期:2007-09-01 00:00:00
abstract:Background::Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Brazil, and primary prevention care may be guided by risk stratification tools. The Framingham (FRS) and QRISK-2 (QRS) risk scores estimate 10-year overall cardiovascular risk in asymptomatic individuals, but the instrument of c...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20170057
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) is a cardiac arrhythmia with high risk for thromboembolic events, specially stroke. OBJECTIVE:To assess the safety of left atrial appendage closure (LAAC) with the Amplatzer Cardiac Plug for the prevention of thromboembolic events in patients with nonvalvular AF. METHODS:This study...
journal_title:Arquivos brasileiros de cardiologia
pub_type: 杂志文章
doi:10.5935/abc.20170167
更新日期:2017-12-01 00:00:00